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1. Full Text Emerging roles of Notch signaling in liver disease
by Geisler, Fabian and Strazzabosco, Mario
Hepatology, ISSN 0270-9139, 01/2015, Volume 61, Issue 1, pp. 382 - 392
This review critically discusses the most recent advances in the role of Notch signaling in liver development, homeostasis, and disease. It is now clear that... 
INACTIVATION | HEPATOCYTES | ALAGILLE-SYNDROME | PATHWAY | REGENERATION | INTRAHEPATIC BILE-DUCTS | HEPATIC PROGENITOR CELLS | MICE | HUMAN HEPATOCELLULAR-CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | HUMAN JAGGED1 | Liver Regeneration | Animals | Signal Transduction | Receptors, Notch - metabolism | Humans | Liver - metabolism | Liver Neoplasms - metabolism | Liver - growth & development | Homeostasis | Signal transduction | Medical research | Liver | hepatic progenitor cells | liver fibrosis | liver disease | Notch signaling | liver repair | liver development | liver regeneration | hepatocellular carcinoma | intrahepatic cholangiocarcinoma
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2. Full Text EASL Recognition Award 2013: Professor Jesus Prieto
by Strazzabosco, Mario
Journal of Hepatology, ISSN 0168-8278, 09/2013, Volume 59, Issue 3, pp. 408 - 410
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3. Toward a rational management of very early hepatocellular carcinoma
by Mario Strazzabosco
Hepatology, ISSN 0270-9139, 04/2013, Volume 57, Issue 4, p. 1300
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4. Full Text EASL Recognition Awardee 2013: Professor Jesus Prieto
by Strazzabosco, Mario
Journal of Hepatology, ISSN 0168-8278, 09/2013, Volume 59, Issue 3, pp. 408 - 410
CELLS | ANION-EXCHANGER | HEPATOCELLULAR-CARCINOMA | LIVER-REGENERATION | PRIMARY BILIARY-CIRRHOSIS | RATS | INTRATUMORAL INJECTION | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | GROWTH-FACTOR-I | CARDIOTROPHIN-1 | Cytokines - history | Growth Substances - history | History, 21st Century | Europe | History, 20th Century | Humans | Awards and Prizes | Genetic Therapy - history | Liver - physiopathology | Cytokines - physiology | Spain | Animals | Societies, Medical | Growth Substances - physiology | Gastroenterology - history | Liver Cirrhosis, Biliary - etiology | Liver Cirrhosis, Biliary - history
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5. Full Text Toward a rational management of very early hepatocellular carcinoma
by Strazzabosco, Mario
Hepatology, ISSN 0270-9139, 04/2013, Volume 57, Issue 4, pp. 1300 - 1302
SURVIVAL | CIRRHOSIS | RECURRENCE | SURGICAL RESECTION | GASTROENTEROLOGY & HEPATOLOGY | RADIOFREQUENCY ABLATION | TRANSPLANTATION | Humans | Carcinoma, Hepatocellular - pathology | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - pathology | Liver Neoplasms - surgery | Male | Hepatectomy
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6. Full Text Development of the bile ducts: Essentials for the clinical hepatologist
by Strazzabosco, Mario and Fabris, Luca
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 56, Issue 5, pp. 1159 - 1170
Summary Several cholangiopathies result from a perturbation of developmental processes. Most of these cholangiopathies are characterised by the persistence of... 
Gastroenterology and Hepatology | PLATE MALFORMATIONS | INTRAHEPATIC BILIARY EPITHELIUM | ALAGILLE-SYNDROME | ADHESION MOLECULE | POLYCYSTIC KIDNEY-DISEASE | LIVER PROGENITOR CELLS | CONGENITAL DISORDERS | VON-MEYENBURG COMPLEXES | GASTROENTEROLOGY & HEPATOLOGY | ENDOTHELIAL GROWTH-FACTOR | GATA TRANSCRIPTION FACTORS | Epithelium - pathology | Liver - pathology | Bile Duct Diseases - etiology | Humans | Epithelium - physiopathology | Liver Diseases - pathology | Bile Ducts - physiopathology | Liver - physiopathology | Liver - embryology | Epithelium - embryology | Bile Duct Diseases - physiopathology | Liver Diseases - etiology | Liver Diseases - physiopathology | Bile Duct Diseases - pathology | Bile Ducts - pathology | Morphogenesis - physiology | Bile Ducts - embryology | Keratin | Immunoglobulins | Genetic disorders | Endothelial growth factors | Kidney diseases | Transforming growth factors | Intermediate filament proteins | Vascular endothelial growth factor | Endothelium | Protein binding
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7. Full Text EASL Recognition Awardee 2013
by Strazzabosco, Mario
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 59, Issue 3, pp. 408 - 410
Gastroenterology and Hepatology
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8. Full Text Src kinase inhibition reduces inflammatory and cytoskeletal changes in ΔF508 human cholangiocytes and improves cystic fibrosis transmembrane conductance regulator correctors efficacy
by Fiorotto, Romina and Amenduni, Mariangela and Mariotti, Valeria and Fabris, Luca and Spirli, Carlo and Strazzabosco, Mario
Hepatology, ISSN 0270-9139, 03/2018, Volume 67, Issue 3, pp. 972 - 988
Cystic fibrosis transmembrane conductance regulator (CFTR), the channel mutated in cystic fibrosis (CF), is expressed by the biliary epithelium (i.e.,... 
Biliary Tract - cytology | Epithelial Cells - metabolism | Cystic Fibrosis - physiopathology | Humans | Quinolones - pharmacology | Aminophenols - pharmacology | Cystic Fibrosis Transmembrane Conductance Regulator - drug effects | Inflammation - metabolism | src-Family Kinases - metabolism | Cell Culture Techniques | Induced Pluripotent Stem Cells - metabolism | Cytokines - metabolism | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Signal Transduction | Chloride Channel Agonists - pharmacology | src-Family Kinases - antagonists & inhibitors | Pyrimidines - pharmacology | Biliary Tract - pathology | Microscopy, Confocal | Animals | Aminopyridines - pharmacology | Fluorescent Antibody Technique | Cytoskeleton - metabolism | Mice | Benzodioxoles - pharmacology | Biliary Tract - drug effects | Cystic Fibrosis - drug therapy | Protein kinase A | Phosphorylation | Liver diseases | Secretion | Cystic fibrosis | Inflammation | Src protein | Epithelium | Kinases | Cell activation | Lymphocytes B | Actin | Stem cells | Toll-like receptors | Cytoskeleton | Polarity | Conductance | Chemokines | Monocyte chemoattractant protein 1 | Pluripotency | Inhibitory postsynaptic potentials
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9. Full Text Forecasting Hepatitis C liver disease burden on real‐life data. Does the hidden iceberg matter to reach the elimination goals?
by Kondili, Loreta A and Robbins, Sarah and Blach, Sarah and Gamkrelidze, Ivane and Zignego, Anna L and Brunetto, Maurizia R and Raimondo, Giovanni and Taliani, Gloria and Iannone, Andrea and Russo, Francesco P and Santantonio, Teresa A and Zuin, Massimo and Chessa, Luchino and Blanc, Pierluigi and Puoti, Massimo and Vinci, Maria and Erne, Elke M and Strazzabosco, Mario and Massari, Marco and Lampertico, Pietro and Rumi, Maria G and Federico, Alessandro and Orlandini, Alessandra and Ciancio, Alessia and Borgia, Guglielmo and Andreone, Pietro and Caporaso, Nicola and Persico, Marcello and Ieluzzi, Donatella and Madonia, Salvatore and Gori, Andrea and Gasbarrini, Antonio and Coppola, Carmine and Brancaccio, Giuseppina and Andriulli, Angelo and Quaranta, Maria G and Montilla, Simona and Razavi, Homie and Melazzini, Mario and Vella, Stefano and Craxì, Antonio and PITER Collaborating Grp and PITER Collaborating Group
Liver International, ISSN 1478-3223, 12/2018, Volume 38, Issue 12, pp. 2190 - 2198
Background & Aims Advances in direct-acting antiviral treatment of HCV have reinvigorated public health initiatives aimed at identifying affected individuals.... 
HCV | chronic infection | linkage to care | WHO | VIRUS-INFECTION | RISK-FACTORS | NATIONAL PROGRESS | UNIVERSAL | PREVALENCE | GENERAL-POPULATION | INJECT DRUGS | PEOPLE | GASTROENTEROLOGY & HEPATOLOGY | EPIDEMIOLOGY | HCV-INFECTION | Antiviral agents | Evaluation | Hepatitis C virus | Hepatitis C | Analysis | Hepatitis | Screening | Liver diseases | Liver | Strategy | Birth | Icebergs | Patients | Public health | Viral Hepatitis
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10. Full Text Neural cell adhesion molecule and polysialic acid in ductular reaction: The puzzle is far from completed, but the picture is becoming more clear
by Strazzabosco, Mario and Fabris, Luca
Hepatology, ISSN 0270-9139, 11/2014, Volume 60, Issue 5, pp. 1469 - 1472
FIBROSIS | GASTROENTEROLOGY & HEPATOLOGY | NCAM | LIVER | PLASTICITY | Male | Liver Regeneration | Animals | Neural Cell Adhesion Molecules - metabolism | Sialic Acids - metabolism
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11. Full Text Foxa1 and Foxa2 regulate bile duct development in mice
by Strazzabosco, Mario
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 52, Issue 5, pp. 765 - 767
COMMENTARY ON: Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest 2009;119:1537–45. Journal of Clinical Investigation. Online by Li Z. et... 
Gastroenterology and Hepatology | DISORDERS | MECHANISMS | GASTROENTEROLOGY & HEPATOLOGY | CHOLANGIOPATHIES | LIVER
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12. Full Text Osteopontin: a new player in regulating hepatic ductular reaction and hepatic progenitor cell responses during chronic liver injury
by Strazzabosco, Mario and Fabris, Luca and Albano, Emanuele
Gut, ISSN 0017-5749, 11/2014, Volume 63, Issue 11, pp. 1693 - 1694
  Several studies indicate that the extent of DR closely correlates with the amount of collagen deposition, ultimately leading to tissue scarring and lobular... 
LIVER REGENERATION | BILIARY EPITHELIUM | CHRONIC LIVER DISEASE | FIBROSIS | GASTROENTEROLOGY & HEPATOLOGY | Hepatic Duct, Common - pathology | Liver Cirrhosis - pathology | Animals | Liver Cirrhosis - physiopathology | Transforming Growth Factor beta - metabolism | Osteopontin - physiology | Motility | Liver diseases | Cytokines | Liver cirrhosis | Rodents | Collagen
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13. Full Text Value‐based care in hepatology
by Strazzabosco, Mario and Allen, John I and Teisberg, Elizabeth O
Hepatology, ISSN 0270-9139, 05/2017, Volume 65, Issue 5, pp. 1749 - 1755
The migration from legacy fee‐for‐service reimbursement to payments linked to high‐value health care is accelerating in the United States because of new... 
QUALITY-OF-CARE | MANAGEMENT | INDICATORS | CIRRHOSIS | CHRONIC HEPATITIS-C | IMPROVEMENT | HEALTH-CARE | LIVER-DISEASE | PATIENT OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | LIFE | Gastroenterology - economics | Value-Based Insurance | Outcome Assessment (Health Care) | Delivery of Health Care | Gastroenterology - standards | Humans | Liver diseases | Patients | Hepatology | Chronic illnesses | Transformation | Decision making | Legislation | Migration | Cognitive ability
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14. Full Text Notch signaling and new therapeutic options in liver disease
by Morell, Carola Maria and Strazzabosco, Mario
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 4, pp. 885 - 890
Summary Notch signaling is a crucial determinant of cell fate decision during development and disease in several organs. Notch effects are strictly dependent... 
Gastroenterology and Hepatology | Notch inhibitors | Liver cancer | Liver repair | Notch signaling | CHOLANGIOCARCINOMA | INTRAHEPATIC BILE-DUCTS | CELL FATE | HUMAN JAGGED1 | ALAGILLE-SYNDROME | PATHWAY | MICE | MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | TUMOR-GROWTH | EXPRESSION | Liver Regeneration | Receptors, Notch - metabolism | Humans | Liver - metabolism | Translational Medical Research | Liver Diseases - therapy | Liver - growth & development | Liver Neoplasms - etiology | Receptors, Notch - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Models, Biological | Liver Neoplasms - metabolism | Adult | Liver Diseases - metabolism | Health aspects | Care and treatment | Liver diseases
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15. Full Text Notch Signaling in Hepatocellular Carcinoma: Guilty in Association
by Strazzabosco, Mario and Fabris, Luca
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 6, pp. 1430 - 1434
Gastroenterology and Hepatology | CELLS | ACTIVATION | ALAGILLE-SYNDROME | GENE | GROWTH | ALPHA | MECHANISMS | GASTROENTEROLOGY & HEPATOLOGY | Animals | Carcinoma, Hepatocellular - physiopathology | Humans | Liver Neoplasms - physiopathology | Receptors, Notch - physiology | Signal Transduction - physiology | Gene Expression Regulation, Neoplastic - physiology
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16. Full Text Effective but costly: How to tackle difficult trade‐offs in evaluating health improving technologies in liver diseases
by Mantovani, Lorenzo Giovanni and Cortesi, Paolo Angelo and Strazzabosco, Mario
Hepatology, ISSN 0270-9139, 10/2016, Volume 64, Issue 4, pp. 1331 - 1342
In the current context of rising health care costs and decreasing sustainability, it is becoming increasingly common to resort to decision analytical modeling... 
DYNAMIC SIMULATION | A VACCINATION | HEPATOCELLULAR-CARCINOMA | DECISION-ANALYSIS | ECONOMIC-EVALUATION | VIRUS | SOFOSBUVIR | CHRONIC HEPATITIS-C | DIRECT-ACTING ANTIVIRALS | GASTROENTEROLOGY & HEPATOLOGY | REGIMENS | Health Care Costs | Cost-Benefit Analysis | Humans | Liver Diseases - economics | Decision Support Techniques | Models, Economic | Biomedical Technology - economics | Sustainability | Health economics | Liver diseases
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