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PLoS Biology, ISSN 1544-9173, 04/2018, Volume 16, Issue 4, pp. e2004399 - e2004399
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) respond to numerous hormonal and neural signals, resulting in changes in... 
TRPV CHANNEL SUBUNITS | ALPHA-MSH | ENERGY HOMEOSTASIS | PAIN PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROOPIOMELANOCORTIN NEURONS | BIOLOGY | ION-CHANNEL | VANILLOID RECEPTOR | DIET-INDUCED OBESITY | LEPTIN RESISTANCE | EXPRESSION | Temperature | Capsaicin - pharmacology | Arcuate Nucleus of Hypothalamus - cytology | Male | Neurons - cytology | Optogenetics | Channelrhodopsins - metabolism | TRPV Cation Channels - deficiency | Arcuate Nucleus of Hypothalamus - drug effects | Receptors, Melanocortin - metabolism | Female | Neurons - metabolism | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Single-Cell Analysis | Genes, Reporter | Physical Conditioning, Animal | Signal Transduction | Arcuate Nucleus of Hypothalamus - metabolism | TRPV Cation Channels - agonists | Bacterial Proteins - genetics | Gene Expression Regulation | Mice, Transgenic | Channelrhodopsins - genetics | Gene Knockout Techniques | Eating - genetics | Receptors, Melanocortin - genetics | TRPV Cation Channels - genetics | Gene Knock-In Techniques | Pro-Opiomelanocortin - metabolism | Eating - drug effects | Animals | Enhancer Elements, Genetic | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Luminescent Proteins - metabolism | Immunohistochemistry | Capsaicin | Arcuate nucleus | Fluorescence | Electrophysiology | Reverse transcription | Capsaicin receptors | Viruses | Proopiomelanocortin | Activation | Hypothalamus | Proteins | Depolarization | Transient receptor potential proteins | Receptors | Elevation | Temperature effects | Rodents | Physiology | Food | Appetite | CRISPR | Yellow fluorescent protein | Neurons | Fitness equipment | Body temperature | Melanocortin | Gene expression | Medicine | Polymerase chain reaction | Enhancers | Weight control | Food intake | Running | Data collection | Endocrinology | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2006, Volume 12, Issue 5, pp. 534 - 540
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, pp. e0162839 - e0162839
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, pp. 355 - 368
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 05/2009, Volume 101, Issue 5, pp. 2305 - 2316
Journal Article
Neuron, ISSN 0896-6273, 2004, Volume 42, Issue 6, pp. 983 - 991
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 04/2010, Volume 298, Issue 4, pp. 787 - 798
Both insulin and leptin signaling converge on phosphatidylinositol 3-OH kinase [PI(3)K]/3-phosphoinositide-dependent protein kinase-1 (PDK-1)/protein kinase B... 
Phosphoinositide-dependent protein kinase-1 | Pomc | Proopiomelanocortin neurons | Food intake | Forkhead box-containing protein O1 | phosphoinositide-dependent protein kinase-1 | DNA-BINDING | PHYSIOLOGY | BETA-CELLS | ARCUATE NUCLEUS | NEUROPEPTIDE-Y | ENERGY-BALANCE | NERVOUS-SYSTEM CONTROL | BODY-WEIGHT | proopiomelanocortin neurons | TRANSCRIPTION FACTOR FOXO1 | ENDOCRINOLOGY & METABOLISM | INSULIN-RECEPTOR SUBSTRATE-2 | HEPATIC GLUCOSE-PRODUCTION | forkhead box-containing protein O1 | food intake | Chromatin - metabolism | Motor Activity - physiology | Immunoprecipitation | Forkhead Transcription Factors - physiology | Obesity - genetics | Oxygen Consumption - physiology | Pro-Opiomelanocortin - physiology | Eating - physiology | RNA - genetics | TRPP Cation Channels - physiology | Forkhead Transcription Factors - metabolism | Neurons - physiology | Plasmids - genetics | 3-Phosphoinositide-Dependent Protein Kinases | Protein-Serine-Threonine Kinases - metabolism | Adrenocorticotropic Hormone - metabolism | TRPP Cation Channels - metabolism | Glucose Tolerance Test | Gene Expression Regulation - physiology | Mice, Transgenic | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Eating - genetics | TRPP Cation Channels - genetics | Mice, Knockout | RNA - biosynthesis | Animals | Fluorescent Antibody Technique | Pro-Opiomelanocortin - biosynthesis | Forkhead Box Protein O1 | Mice | Physiological aspects | Properties | Insulin | Leptin | Genotype & phenotype | Biochemistry | Kinases | Neurons | Genes | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 49, Issue 2, pp. 191 - 203
Leptin, an adipocyte-derived hormone, acts directly on the brain to control food intake and energy expenditure. An important question is the identity of... 
HUMDISEASE | MOLNEURO | LATERAL HYPOTHALAMIC AREA | GREEN FLUORESCENT PROTEIN | VENTROMEDIAL NUCLEUS | ENERGY HOMEOSTASIS | STEROIDOGENIC FACTOR-1 | NEUROTROPHIC FACTOR | RECEPTOR MESSENGER-RNA | CENTRAL-NERVOUS-SYSTEM | ARCUATE NUCLEUS | NEUROSCIENCES | MELANOCORTIN-4 RECEPTOR | Immunohistochemistry | Ventromedial Hypothalamic Nucleus - drug effects | Steroidogenic Factor 1 | Adipose Tissue - physiology | Electrophysiology | Male | RNA Probes | Body Composition - drug effects | Body Composition - genetics | Leptin - pharmacology | Receptors, Cell Surface - physiology | Homeostasis - drug effects | Energy Metabolism - genetics | Energy Metabolism - physiology | Neurons - drug effects | STAT3 Transcription Factor - metabolism | Body Composition - physiology | Receptors, Leptin | Green Fluorescent Proteins - metabolism | Transcription Factors - physiology | Mice, Transgenic | Obesity - physiopathology | Receptors, Cytoplasmic and Nuclear - physiology | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | Homeodomain Proteins - genetics | Patch-Clamp Techniques | Phenotype | Animals | Diet | Signal Transduction - drug effects | Homeostasis - physiology | Signal Transduction - physiology | Mice | Ventromedial Hypothalamic Nucleus - cytology | Body Weight - physiology | Homeodomain Proteins - physiology | In Vitro Techniques | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Receptors, Cell Surface - genetics | Neurosciences | Peptide hormones | Neurons | Leptin | Proteins | Nutrition research | Data analysis | Brain research | Rodents | Homeostasis | Neuropeptides |