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by Devereaux, P.J and Devereaux, P J and Duceppe, Emmanuelle and Guyatt, Gordon and Tandon, Vikas and Rodseth, Reitze and Biccard, Bruce M and Xavier, Denis and Szczeklik, Wojciech and Meyhoff, Christian S and Vincent, Jessica and Franzosi, Maria Grazia and Srinathan, Sadeesh K and Erb, Jason and Magloire, Patrick and Neary, John and Rao, Mangala and Rahate, Prashant V and Rahate, Prashant and Chaudhry, Navneet and Chaudhry, Navneet K and Mayosi, Bongani and Mayosi, Bogani and de Nadal, Miriam and Iglesias, Pilar Paniagua and Berwanger, Otavio and Villar, Juan Carlos and Botto, Fernando and Eikelboom, John and Eikelboom, John W and Sessler, Daniel I and Kearon, Clive and Pettit, Shirley and Sharma, Mukul and Sharma, Ambika and Sharma, Mike and Connolly, Stuart and Connolly, Stuart J and Bangdiwala, Shrikant I and Rao-Melacini, Purnima and Hoeft, Andreas and Yusuf, Salim and Pogue, Janice and Di Diodato, Sara and Gasic, Zora and Mastrangelo, Louise J and Molnar, Sarah H and Swanson, Jennifer L and Tosh, Makayla L and Wells, Jennifer R and Wells, George A and Diaz, Rafael and Chow, Clara K and Gonzales, Beatriz and Vásquez, Skarlet and Jansky, Petr and Dušek, Radovan and Coriat, Pierre and Wittmann, Maria and Yonga, Gerald and Mathur, Nandini and Seletti, Elena and Malaga, German and Tumanan-Mendoza, Bernadette A and Tagle, Maria Pamela A and Alonso-Coello, Pablo and Popova, Ekaterine and Shields, Martin O and Shields, Martin and Le Manach, Yannick and Moayyedi, Paul and van Zanten, Sander and Fleischmann, Edith and Garg, Amit and Karaye, Kamilu and McFalls, Edward and Sigamani, Alben and Belley-Côté, Emilie and Biedroń, Grzegorz and Borges, Flavia and Frosi Stella, Steffan and Haarmark Nielsen, Christian and Leong, Darryl P and Spence, Jessica and Tran, Allen and Wawrzycka-Adamczyk, Katarzyna and Yang, Stephen S and Yung, Terence and Wyse, D. George and Cheng, Davy and Johnstone, David E and Joseph, Philip and Patel, Ameen and Gregus, Krysten and Lawrence, Kelly and Doharris, Lindsay and Conen, David and Cheung, Jason and Douketis, Jim and Wright, Douglas and ... and MANAGE Investigators
The Lancet, ISSN 0140-6736, 06/2018, Volume 391, Issue 10137, pp. 2325 - 2334
Myocardial injury after non-cardiac surgery (MINS) increases the risk of cardiovascular events and deaths, which anticoagulation therapy could prevent.... 
DEFINITION | MORTALITY | MEDICINE, GENERAL & INTERNAL | THERAPY | EVENTS | RIVAROXABAN | DOUBLE-BLIND | ELEVATION | ACUTE CORONARY SYNDROMES | ASPIRIN | Troponin - drug effects | Dabigatran - adverse effects | Myocardial Infarction - epidemiology | Myocardial Infarction - mortality | Dabigatran - administration & dosage | Humans | Stroke - complications | Male | Hemorrhage - prevention & control | Peripheral Arterial Disease - complications | Venous Thromboembolism - drug therapy | Antithrombins - pharmacology | Venous Thromboembolism - prevention & control | Aged, 80 and over | Female | Dabigatran - pharmacology | Troponin - metabolism | Omeprazole - therapeutic use | Stroke - prevention & control | Placebo Effect | Omeprazole - administration & dosage | Perioperative Period - mortality | Hemorrhage - complications | Peripheral Arterial Disease - drug therapy | Treatment Outcome | Stroke - drug therapy | Proton Pump Inhibitors - therapeutic use | Peripheral Arterial Disease - prevention & control | Thrombosis - pathology | Hemorrhage - drug therapy | Myocardial Infarction - drug therapy | Aged | Clinical trials | Anesthesia | Care and treatment | Analysis | Cardiac patients | Heart | Myocardial infarction | Cardiac arrhythmia | Heart attacks | Embolisms | Heart surgery | Risk | Cardiovascular disease | Family medical history | Bleeding | Randomization | Motivation | Safety engineering | Surgery | Amputation | Safety | Thromboembolism | Heart diseases | Anticoagulants | Cerebral infarction | Stroke | Aspirin | Complications | Mortality | Health risks | Patients | Thrombosis | Omeprazole | Sepsis | Infarction | Adults | Cardiovascular diseases | Health risk assessment | Factorial design
Journal Article
European Journal of Anaesthesiology, ISSN 0265-0215, 08/2019, Volume 36, Issue 8, pp. 617 - 618
Journal Article
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, ISSN 0832-610X, 11/2019, Volume 66, Issue 11, pp. 1338 - 1346
We performed a retrospective cohort study in patients who underwent endovascular aneurysm repair (EVAR) to determine the incidence and predictors of myocardial... 
Pediatrics | Pain Medicine | Pneumology/Respiratory System | Medicine & Public Health | Intensive / Critical Care Medicine | Anesthesiology | Cardiology
Journal Article
Artery Research, ISSN 1872-9312, 2015, Volume 12, pp. 30 - 30
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0122831
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0169420
Intracellular Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA (dsRNA) and activates antiviral immune responses through the production of type... 
TOLL-LIKE RECEPTOR-3 | PLASMACYTOID DENDRITIC CELLS | NATURAL-RESISTANCE | IMMUNE-RESPONSE | DOUBLE-STRANDED-RNA | INNATE ANTIVIRAL RESPONSES | LIVER-TRANSPLANTATION | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | CHRONIC HEPATITIS-C | RIG-I | Haplotypes | Humans | Child, Preschool | Infant | Male | Cytomegalovirus Infections - genetics | Case-Control Studies | Endosomes - metabolism | Female | Toll-Like Receptor 3 - genetics | Child | Toll-Like Receptor 7 - genetics | Cytomegalovirus | Genetic Predisposition to Disease | Genotype | Antiviral Agents | DNA, Viral - urine | Gene Dosage | Models, Statistical | Linkage Disequilibrium | DNA, Viral - blood | Polymorphism, Restriction Fragment Length | Alleles | Heterozygote | Polymorphism, Single Nucleotide | Cytomegalovirus infections | Genetic aspects | Children | Single nucleotide polymorphisms | Research | Health aspects | Risk factors | Pediatrics | Laboratories | Copy number | Genes | Linkage disequilibrium | Viruses | Biology | Infections | Single-nucleotide polymorphism | Gene polymorphism | Proteins | Hepatitis | Newborn babies | Toll-like receptors | Deoxyribonucleic acid--DNA | Immune system | Urine | Immunoglobulins | Immune response | TLR7 protein | Congenital diseases | Cytokines | Dendritic cells | Capillary electrophoresis | Gynecology | Double-stranded RNA | Health risks | Inflammation | Ribonucleic acid--RNA | TLR3 protein | Virology | Studies | Polymerase chain reaction | Restriction fragment length polymorphism | Genotyping | Interferon | Viral infections | Endosomes | Polymorphism | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0154100
Toll-like receptor 9 (TLR9) recognizes non-methylated viral CpG-containing DNA and serves as a pattern recognition receptor that signals the presence of human... 
PLASMACYTOID DENDRITIC CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | TLR9 GENE | LIVER-TRANSPLANTATION | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE RECEPTOR | SINGLE-NUCLEOTIDE POLYMORPHISM | CMV INFECTION | ADAPTER PROTEIN | GLYCOPROTEIN-B | VIRUS TYPE-1 | Cytomegalovirus - genetics | Genetic Predisposition to Disease - genetics | Gene Frequency | Humans | Risk Factors | Toll-Like Receptor 9 - genetics | Genotype | Infant | Logistic Models | Male | Gene Dosage | Cytomegalovirus Infections - genetics | Host-Pathogen Interactions | Polymorphism, Restriction Fragment Length | Alleles | Polymerase Chain Reaction | Cytomegalovirus Infections - virology | Female | Polymorphism, Single Nucleotide | DNA, Viral - genetics | Odds Ratio | Cytomegalovirus - physiology | Physiological aspects | Toll-like receptors | Cytomegalovirus infections | Development and progression | Genetic aspects | Single nucleotide polymorphisms | Research | Risk factors | Copy number | Linkage disequilibrium | Infants | Infections | Single-nucleotide polymorphism | Gene polymorphism | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Electrophoresis | Children | Genotypes | Deoxyribonucleic acid--DNA | CpG islands | Cytomegalovirus | Capillary electrophoresis | Health risks | Pattern recognition | TLR9 protein | Polymerase chain reaction | Restriction fragment length polymorphism | Genotyping | Viral infections | Polymorphism | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | DNA | Human immunodeficiency virus
Journal Article
Canadian Journal of Anesthesia / Journal canadien d'anesthesie, ISSN 0832-610X, 11/2019, Volume 66, Issue 11, p. 1338
We performed a retrospective cohort study in patients who underwent endovascular aneurysm repair (EVAR) to determine the incidence and predictors of myocardial... 
Journal Article
Intensive Care Medicine, ISSN 0342-4642, 7/2018, Volume 44, Issue 7, pp. 1027 - 1038
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 10/2015, Volume 87, Issue 10, pp. 1737 - 1748
Cytomegalovirus (CMV) is the most common cause of congenital infection. This pathogen exhibits extensive genetic variability in the genes that encode... 
glycoprotein B (gB) | gene polymorphism | US28 | UL144 | cytomegalovirus (CMV) | congenital and postnatal infection | Congenital and postnatal infection | Glycoprotein B (gB) | Gene polymorphism | Cytomegalovirus (CMV) | SEQUENCE-ANALYSIS | NECROSIS-FACTOR RECEPTOR | GLYCOPROTEIN-B GENOTYPE | TRANSPLANT RECIPIENTS | JAPANESE CHILDREN | DRIED BLOOD SPOTS | MIXED INFECTION | MATERNAL INFECTION | VIROLOGY | CLINICAL-MANIFESTATIONS | CMV INFECTION | Membrane Glycoproteins - urine | Viral Proteins - urine | Biomarkers - urine | Receptors, Chemokine - blood | Asymptomatic Infections - epidemiology | Cytomegalovirus Infections - epidemiology | Humans | Viral Envelope Proteins | Infant | Phylogeny | Viral Load | Membrane Glycoproteins - cerebrospinal fluid | Time Factors | Cytomegalovirus Infections - virology | Cytomegalovirus Infections - congenital | Receptors, Chemokine - genetics | Real-Time Polymerase Chain Reaction | Infant, Newborn | Amino Acid Sequence | Cytomegalovirus - genetics | Membrane Glycoproteins - blood | Viral Proteins - blood | Viral Proteins - genetics | Genotype | Biomarkers - blood | Membrane Glycoproteins - genetics | Polymorphism, Genetic | Sequence Alignment | Viral Proteins - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Sequence Analysis | Biomarkers - chemistry | Infants (Newborn) | Cytomegalovirus infections | Genetic aspects | Glycoproteins | Analysis | Babies | Cytomegalovirus | Genotype & phenotype | Viral infections
Journal Article