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Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 08/2019, Volume 136, p. 104939
The liver is a well-known immunotolerogenic environment, which provides the adequate setting for liver infectious pathogens persistence such as the hepatitis B... 
Systems pharmacology | Topological model | Liver immunology | Hepatitis B | Immune system | DENDRITIC CELLS | LYMPHOCYTE ACTIVATION | INNATE | MEMORY B | GERMINAL CENTER SELECTION | VIRUS INFECTION | REGULATORY T-CELLS | HUMORAL IMMUNITY | PHARMACOLOGY & PHARMACY | GENERATION | EXPRESSION
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2018, Volume 36, Issue 6_suppl, pp. 411 - 411
411 Background: Although immune checkpoint inhibitors (ICI) have improved outcomes in some pts with platinum-resistant mUC, many pts (eg, pts with TCGA luminal... 
Journal Article
Applied Physiology, Nutrition and Metabolism, ISSN 1715-5312, 2014, Volume 39, Issue 6, pp. 693 - 698
Journal Article
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 6/2008, Volume 62, Issue 1, pp. 135 - 147
Reversible transient elevations in transaminases have been observed after trabectedin administration. A semimechanistic pharmacokinetic and pharmacodynamic... 
Biomedicine | Dexamethasone | Tolerance | Oncology | Cancer Research | Pharmacology/Toxicology | Population Pharmacokinetics/pharmacodynamics | Trabectedin | Liver toxicity | Transaminitis | Dose reduction | NONMEM | dexamethasone | ADVANCED BREAST-CANCER | SOFT-TISSUE SARCOMAS | ONCOLOGY-GROUP | RAT HEPATOCYTES | SOLID TUMORS | pharmacodynamics | dose reduction | MARINE COMPOUND | population Pharmacokinetics | CONTINUOUS INTRAVENOUS-INFUSION | liver toxicity | ONCOLOGY | trabectedin | LIVER | PHARMACOLOGY & PHARMACY | transaminitis | ANTICANCER AGENT ECTEINASCIDIN-743 | PHASE-I | tolerance | Dioxoles - adverse effects | Humans | Middle Aged | Male | Alanine Transaminase - blood | Dexamethasone - pharmacology | Antineoplastic Agents - adverse effects | Computer Simulation | Aged, 80 and over | Adult | Anti-Inflammatory Agents - pharmacokinetics | Female | Finite Element Analysis | Chemical and Drug Induced Liver Injury - enzymology | Chemical and Drug Induced Liver Injury - prevention & control | Data Interpretation, Statistical | Anti-Inflammatory Agents - pharmacology | Drug Tolerance | Tetrahydroisoquinolines - adverse effects | Models, Statistical | Dexamethasone - pharmacokinetics | Algorithms | Analysis of Variance | Intercalating Agents - adverse effects | Transaminases - blood | Aged | Software | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic | Models | Drug interactions | Analysis | Steroids
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 4_suppl, pp. 39 - 39
39 Background: Abiraterone, the active metabolite of abiraterone acetate (AA), is an effective androgen biosynthesis inhibitor for patients with metastatic... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 4_suppl, pp. 58 - 58
58 Background: Abiraterone acetate (AA) is an effective therapy for patients with metastatic castration-resistant prostate cancer (mCRPC). AA is metabolized to... 
Journal Article