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by Yamamoto, Seiichiro and Hinoi, Takao and Niitsu, Hiroaki and Okajima, Masazumi and Ide, Yoshihito and Murata, Kohei and Akamoto, Shintaro and Kanazawa, Akiyoshi and Nakanishi, Masayoshi and Naitoh, Takeshi and Kanehira, Eiji and Shimamura, Tsukasa and Suzuka, Ichio and Fukunaga, Yosuke and Yamaguchi, Takashi and Watanabe, Masahiko and Shiozawa, Kunihisa and Bando, Hiroyuki and Yamamoto, Daisuke and Kitano, Seigo and Inomata, Masafumi and Akagi, Tomonori and Okuda, Junji and Tanaka, Keitaro and Yasui, Masayoshi and Hirakawa, Kosei and Maeda, Kiyoshi and Hasegawa, Junichi and Nishimura, Junichi and Kuroyanagi, Hiroya and Horie, Hisanaga and Naito, Masaki and Ueki, Takashi and Sakai, Yoshiharu and Hida, Koya and Kinjo, Yousuke and Kokuba, Yukihito and Hamada, Madoka and Saito, Norio and Ito, Masaaki and Yatsuoka, Toshimasa and Tashiro, Jo and Yamaguchi, Shigeki and Furuhata, Tomohisa and Okita, Kenji and Kubo, Yoshiro and Saito, Shuji and Kinugasa, Yusuke and Konishi, Fumio and Sakamoto, Kazuhiro and Goto, Michitoshi and Tanaka, Junichi and Endo, Shungo and Miyajima, Nobuyoshi and Suda, Tadashi and Saida, Yoshihisa and Enomoto, Toshiyuki and Munakata, Yasuhiro and Hayashi, Ken and Tagami, Souichi and Takii, Yasumasa and Maruyama, Satoshi and Ichihara, Takao and Idani, Hitoshi and Kurose, Kohei and Miyake, Yasuhiro and Hazama, Shoichi and Fujii, Shoichi and Yamagishi, Shigeru and Watanabe, Kazuteru and Sugihara, Kenichi and Fujita, Shin and Japan Soc Laparoscopic Colorectal and Japan Society of Laparoscopic Colorectal Surgery and for the Japan Society of Laparoscopic Colorectal Surgery
Journal of Gastroenterology, ISSN 0944-1174, 06/2017, Volume 52, Issue 6, pp. 695 - 704
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Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2015, Volume 85, pp. 183 - 198
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Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A11323 - A11323
IntroductionHeart failure has become one of the most concerned issues providing huge social and economic burdens as aging population grows. There is evidence... 
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Journal of the American College of Cardiology, ISSN 0735-1097, 01/2018, Volume 71, Issue 1, pp. 102 - 104
The mechanisms underlying the lower risk of hemorrhagic complications during treatment with direct oral anticoagulants (DOAC) have not been well clarified.... 
CARDIAC & CARDIOVASCULAR SYSTEMS | Anticoagulants | Cardiac arrhythmia | Catheters | Coagulation | Index Medicus | Abridged Index Medicus
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PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, pp. e0182422 - e0182422
Dipeptidyl peptidase 4 inhibitors are used worldwide in the management of diabetes, but their role in the prevention or treatment of cardiovascular disorders... 
VENTRICULAR FUNCTION | GEL DIGESTION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | L-ARGININE | MOUSE MODEL | ENERGY-METABOLISM | L-CITRULLINE | BLOOD-PRESSURE | ORAL SUPPLEMENTATION | Linagliptin - pharmacology | Amino Acid Sequence | Myocardial Ischemia - metabolism | Dipeptidyl Peptidase 4 - metabolism | Heart Diseases - metabolism | Rats, Wistar | Obesity - complications | Dipeptidyl Peptidase 4 - chemistry | Mice, Inbred C57BL | Cells, Cultured | Myocardial Ischemia - prevention & control | Rats | Systole - drug effects | Heart Diseases - prevention & control | Male | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Gene Expression Regulation - drug effects | Sequence Homology | Heart Diseases - etiology | Animals | Myocardial Ischemia - etiology | Fibroblast Growth Factor 2 - metabolism | Mice | Early Growth Response Protein 1 - metabolism | Care and treatment | Ischemia | Proteases | Physiological aspects | Genetic aspects | Linagliptin | Research | Risk factors | Heart | Neonates | Fibroblast growth factor | Peptides | Cardiomyopathy | Disorders | Biology | Rarefaction | Kinases | Creatine | Remodeling | Angiogenesis | Metabolites | Rodents | Inhibition | Vascular endothelial growth factor | Growth factors | Heart diseases | Deoxyribonucleic acid--DNA | University graduates | Recombinant | Heart failure | Fibroblast growth factor 2 | Obesity | Peptidase | EGR-1 protein | Incubation | Capillary electrophoresis | Diabetes mellitus | Cardiomyocytes | Mass spectroscopy | Pharmacology | Citrulline | Metabolism | Medicine | Studies | Pathology | DNA microarrays | Diet | Insulin resistance | Scientific imaging | Diabetes | Mass spectrometry | Metabolic disorders | Index Medicus | Deoxyribonucleic acid | DNA
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Journal of Cardiac Failure, ISSN 1071-9164, 10/2017, Volume 23, Issue 10, pp. S55 - S55
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SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3858 - 7
We previously demonstrated that cellular aging signals upregulated a secreted class 3 semaphorin E (Sema3E) and its receptor plexinD1 in the adipose tissue of... 
SENESCENT CELLS | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | P53 | Glucose tolerance | Obesity | Intolerance | Animal models | Adipose tissue | Peptides | Diabetes mellitus | Aging | Inflammation | Vaccines | Macrophages | Enzyme-linked immunosorbent assay
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PLoS ONE, ISSN 1932-6203, 02/2019, Volume 14, Issue 2, pp. e0212889 - e0212889
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Japanese Journal of Thrombosis and Hemostasis, ISSN 0915-7441, 2019, Volume 30, Issue 3, pp. 521 - 528
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Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A15231 - A15231
Brown adipose tissue (BAT) is a metabolically active organ that contributes to the maintenance of healthy metabolism. Adrenergic signaling is well described as... 
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Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A11299 - A11299
Accumulating evidence has revealed that cellular senescence plays a pivotal role in aging and age-related cardiometabolic disorders including atherosclerosis,... 
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PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e100359 - e100359
Evolutionarily conserved Notch signaling controls cell fate determination and differentiation during development, and is also essential for neovascularization... 
TELOMERE | ANGIOGENESIS | REPRESSION | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | MUSCLE | DIFFERENTIATION | P16(INK4A) | STRESS | CELLULAR SENESCENCE | EXPRESSION | Human Umbilical Vein Endothelial Cells - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Membrane Proteins - genetics | Humans | Intercellular Signaling Peptides and Proteins - genetics | Cellular Senescence - drug effects | Receptor, Notch1 - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Up-Regulation - drug effects | Proteolysis - drug effects | Phenotype | Animals | Signal Transduction - drug effects | Serrate-Jagged Proteins | Human Umbilical Vein Endothelial Cells - cytology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Dual Specificity Phosphatase 1 - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Calcium-Binding Proteins - genetics | Jagged-1 Protein | Senescence | Id1 protein | Infections | Biology | Vascularization | MAP kinase phosphatase | Proteins | Angiogenesis | Signal transduction | Vascular diseases | Cell fate | Rodents | Atherosclerosis | Aging | Inhibition | Jagged1 protein | Telomerase | Deoxyribonucleic acid--DNA | University graduates | MAP kinase | Gene expression | Endothelial cells | Medicine | Signaling | Overexpression | Life span | Ligands | Adults | Notch protein | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
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