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Cancer Science, ISSN 1347-9032, 04/2016, Volume 107, Issue 4, pp. 491 - 498
Recently, research into the development of new targeted therapies has focused on specific genetic alterations to create advanced, more personalized treatment.... 
Biomarker | HER | 2‐negative | breast cancer | fibroblast growth factor receptor‐1 | positive | protein expression | Fibroblast growth factor receptor-1 | Protein expression | Breast cancer | ER-positive/HER2-negative | INTERNATIONAL EXPERT CONSENSUS | SURVIVAL | TARGET | PRIMARY THERAPY | HIGHLIGHTS | PROLIFERATION | CHEMOTHERAPY | fibroblast growth factor receptor-1 | RELAPSE | AMPLIFICATION | ONCOLOGY | FGFR1 | Gene Dosage - genetics | Prognosis | Receptors, Estrogen - genetics | Receptor, ErbB-2 - genetics | Humans | Middle Aged | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Neoplasm Recurrence, Local - pathology | RNA, Messenger - biosynthesis | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Adult | Female | Neoplasm Recurrence, Local - genetics | Aged | Biomarkers, Tumor - genetics | Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis | Epidermal growth factor | RNA | Analysis | Estrogen | Genetic research | Phenols | Fibroblast growth factors | Fibroblast growth factor | Transcription | Copy number | Invasiveness | Genomics | Menopause | Estrogen receptors | Kinases | Gene expression | ErbB-2 protein | Patients | Proteins | Studies | Gene amplification | Medical prognosis | Fibroblasts | Fibroblast growth factor receptor 1 | Thermal cycling | Deoxyribonucleic acid--DNA | Fibroblast growth factor receptors | Index Medicus | ER‐positive | HER2‐negative | Original
Journal Article
by Michailidou, Kyriaki and Hall, Per and Gonzalez-Neira, Anna and Ghoussaini, Maya and Dennis, Joe and Milne, Roger L and Schmidt, Marjanka K and Chang-Claude, Jenny and Bojesen, Stig E and Bolla, Manjeet K and Wang, Qin and Dicks, Ed and Lee, Anew and Turnbull, Clare and Rahman, Nazneen and Fletcher, Olivia and Peto, Julian and Gibson, Lorna and dos Santos Silva, Isabel and Nevanlinna, Heli and Muranen, Taru A and Aittomäki, Kristiina and Blomqvist, Carl and Czene, Kamila and Irwanto, Astrid and Liu, Jianjun and Waisfisz, Quinten and Meijers-Heijboer, Hanne and Adank, Muriel and van der Luijt, Rob B and Hein, Rebecca and Dahmen, Norbert and Beckman, Lars and Meindl, Alfons and Schmutzler, Rita K and Müller-Myhsok, Bertram and Lichtner, Peter and Hopper, John L and Southey, Melissa C and Makalic, Enes and Schmidt, Daniel F and Uitterlinden, Ane G and Hofman, Albert and Hunter, David J and Chanock, Stephen J and Vincent, Daniel and Bacot, François and Tessier, Daniel C and Canisius, Sander and Wessels, Lodewyk F. A and Haiman, Christopher A and Shah, Mitul and Luben, Robert and Brown, Judith and Luccarini, Craig and Schoof, Nils and Humphreys, Keith and Li, Jingmei and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Couch, Fergus J and Wang, Xianshu and Vachon, Celine and Stevens, Kristen N and Lambrechts, Diether and Moisse, Matthieu and Paridaens, Robert and Christiaens, Marie-Rose and Rudolph, Anja and Nickels, Stefan and Flesch-Janys, Dieter and Johnson, Nichola and Aitken, Zoe and Aaltonen, Kirsimari and Heikkinen, Tuomas and Broeks, Annegien and van 't Veer, Laura J and van der Schoot, C. Ellen and Guénel, Pascal and Truong, Thérèse and Laurent-Puig, Pierre and Menegaux, Florence and Marme, Frederik and Schneeweiss, Aneas and Sohn, Christof and Burwinkel, Barbara and Zamora, M. Pilar and Perez, Jose Ignacio Arias and Pita, Guillermo and Alonso, M. Rosario and Cox, Angela and Brock, Ian W and Cross, Simon S and Reed, Malcolm W. R and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Henderson, Brian E and ... and kConFab Investigators and GENICA Gene Environm Interaction B and Hereditary Breast Ovarian Canc Res and Australian Ovarian Can Study Grp and Breast Ovarian Canc Susceptibility and Australian Ovarian Cancer Study Group and GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network and Breast and Ovarian Cancer Susceptibility Collaboration and Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and The Breast and Ovarian Cancer Susceptibility Collaboration and The GENICA (Gene Environment Interaction and Breast Cancer in Germany) Network
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 353 - 361
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e116054 - e116054
The phosphoinositide-3-kinase (PI3K) pathway is commonly deregulated in breast cancer through several mechanisms, including PIK3CA mutation and loss of... 
DIGITAL PCR | ACTIVATION | PI3K PATHWAY | MULTIDISCIPLINARY SCIENCES | COPY NUMBER | RESISTANCE | TUMOR-SUPPRESSOR | FOLLOW-UP | SOMATIC MUTATION | PLUS ADJUVANT CHEMOTHERAPY | IMMUNOHISTOCHEMISTRY | PTEN Phosphohydrolase - genetics | Phosphoric Monoester Hydrolases - genetics | Phosphoric Monoester Hydrolases - analysis | Trastuzumab - therapeutic use | Receptor, ErbB-2 - genetics | Humans | Middle Aged | PTEN Phosphohydrolase - analysis | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Breast - metabolism | Breast Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast - drug effects | Breast Neoplasms - pathology | Adult | Female | Aged | Mutation | Receptor, ErbB-2 - analysis | Immunohistochemistry | Inositol | Care and treatment | Gene mutations | Analysis | Breast cancer | Genetic aspects | Deregulation | Copy number | Science | Inositol polyphosphate | Homology | Metastasis | Multivariate analysis | Kinases | Phosphatase | Tissues | Gene sequencing | Epidermal growth factor | Surgery | Bioindicators | Pretreatment | Deoxyribonucleic acid--DNA | University graduates | Tensin | Effectiveness | Gene expression | Patients | ErbB-2 protein | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Studies | Biomarkers | Breast | PTEN protein | Trastuzumab | DNA sequencing | Cancer | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2018, Volume 172, Issue 2, pp. 353 - 362
Journal Article
by French, Juliet D and Ghoussaini, Maya and Edwards, Stacey L and Meyer, Kerstin B and Michailidou, Kyriaki and Ahmed, Shahana and Khan, Sofia and Maranian, Mel J and O’Reilly, Martin and Hillman, Kristine M and Betts, Joshua A and Carroll, Thomas and Bailey, Peter J and Dicks, Ed and Beesley, Jonathan and Tyrer, Jonathan and Maia, Ana-Teresa and Beck, Andrew and Knoblauch, Nicholas W and Chen, Shou-Tung and Chen, Constance and Kraft, Peter and Barnes, Daniel and González-Neira, Anna and Alonso, M. Rosario and Herrero, Daniel and Tessier, Daniel C and Vincent, Daniel and Bacot, Francois and Luccarini, Craig and Baynes, Caroline and Conroy, Don and Dennis, Joe and Bolla, Manjeet K and Wang, Xianshu and Wang, Qin and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Verhoef, Senno and Cornelissen, Sten and Muir, Kenneth and Lophatananon, Artitaya and Stewart-Brown, Sarah and Siriwanarangsan, Pornthep and Fasching, Peter A and Loehberg, Christian R and Ekici, Arif B and Beckmann, Matthias W and Peto, Julian and dos Santos Silva, Isabel and Johnson, Nichola and Aitken, Zoe and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Frederik and Schneeweiss, Andreas and Sohn, Christof and Burwinkel, Barbara and Guénel, Pascal and Truong, Thérèse and Laurent-Puig, Pierre and Menegaux, Florence and Bojesen, Stig E and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Milne, Roger L and Zamora, M. Pilar and Arias Perez, Jose Ignacio and Benitez, Javier and Anton-Culver, Hoda and Brenner, Hermann and Müller, Heiko and Arndt, Volker and Stegmaier, Christa and Meindl, Alfons and Lichtner, Peter and Schmutzler, Rita K and Engel, Christoph and Brauch, Hiltrud and Hamann, Ute and Justenhoven, Christina and Aaltonen, Kirsimari and Heikkilä, Päivi and Aittomäki, Kristiina and Blomqvist, Carl and Matsuo, Keitaro and Ito, Hidemi and Iwata, Hiroji and Sueta, Aiko and Bogdanova, Natalia V and Antonenkova, Natalia N and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and ... and KConFab Investigators and GENICA Network and kConFab Investigators
The American Journal of Human Genetics, ISSN 0002-9297, 04/2013, Volume 92, Issue 4, pp. 489 - 503
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1583 - 1583
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 11/2017, Volume 17, Issue 1, pp. 786 - 786
Background: ESR1 mutations have attracted attention as a potentially important marker and treatment target in endocrine therapy-resistant breast cancer... 
ESR1 mutations | Cell-free DNA | Metastatic breast cancer | E380Q mutation | Acquired endocrine therapy resistance | HETEROGENEITY | THERAPY | ONCOLOGY | DNA | ESTROGEN-RECEPTOR-ALPHA | BINDING DOMAIN | CLINICAL-SIGNIFICANCE | Medical colleges | Care and treatment | Cancer patients | Analysis | Breast cancer | Genetic aspects | Health aspects | Estradiol | Cancer | Index Medicus
Journal Article