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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2015, Volume 112, Issue 31, pp. E4288 - E4297
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 07/2017, Volume 25, Issue 7, pp. 1544 - 1555
Targeted inhibition of oncogenic miRNA-21 has been proposed to treat glioblastoma by rescuing tumor suppressors, PTEN and PDCD4. However, systemic delivery of... 
microRNA | apoptosis | glioblastoma | RNA nanoparticle | 3WJ | THERAPEUTICS | MEDICINE, RESEARCH & EXPERIMENTAL | DOWN-REGULATION | CANCER | CELL-DEATH | DELIVERY | PRNA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GENETICS & HEREDITY | C-ELEGANS | NANOTECHNOLOGY | FOLATE | Oligonucleotides - chemistry | RNA-Binding Proteins - genetics | MicroRNAs - antagonists & inhibitors | Nanoparticles - chemistry | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Drug Carriers | Glioblastoma - genetics | Apoptosis Regulatory Proteins - genetics | Folate Receptors, GPI-Anchored - genetics | Antagomirs - pharmacology | Female | Brain Neoplasms - mortality | PTEN Phosphohydrolase - genetics | Folic Acid - chemistry | Brain Neoplasms - genetics | PTEN Phosphohydrolase - metabolism | Folate Receptors, GPI-Anchored - metabolism | Antagomirs - chemistry | Apoptosis Regulatory Proteins - metabolism | Glioblastoma - therapy | Xenograft Model Antitumor Assays | Oligonucleotides - metabolism | Animals | Mice, Nude | Glioblastoma - pathology | Brain Neoplasms - therapy | Survival Analysis | Cell Line, Tumor | Folic Acid - metabolism | Mice | MicroRNAs - genetics | Nanoparticles - administration & dosage | Antagomirs - metabolism | Glioblastoma - mortality | RNA-Binding Proteins - metabolism | Cell survival | Brain cancer | Genes | Glioblastoma | Cancer therapies | Folic acid | Nanoparticles | MicroRNAs | Cell cycle | miRNA | Glioblastoma cells | Gene therapy | PTEN protein | Evacuations & rescues | Nanotechnology | Deoxyribonucleic acid--DNA | Apoptosis | Original
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 11, pp. 4173 - 4178
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2013, Volume 110, Issue 37, pp. 15043 - 15048
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 09/2018, Volume 25, Issue 9, pp. 1612 - 1624
... change of XPO5 in hepatocellular carcinoma Jiao Li1 ● Wenchen Pu 1 ● Hui-Lung Sun2 ● Jian-Kang Zhou1 ● Xin Fan3 ● Yuanyuan Zheng1 ● Juan He1 ● Xuesha Liu1 ● Zhichu... 
PROLYL-ISOMERASE PIN1 | OVEREXPRESSION | ACTIVATION | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR EXPORT | MIRNAS | BETA-CATENIN | CANCER | EXPRESSION | CELL BIOLOGY | Post-transcription | Phosphorylation | Serine | Isomerization | Extracellular signal-regulated kinase | Proline | Hepatocellular carcinoma | Biosynthesis | Pin1 protein | Liver cancer | MicroRNAs | miRNA | Tumorigenesis | Cytoplasm | Conformation
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2018, Volume 128, Issue 2, pp. 625 - 643
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 400 - 410.e7
MicroRNA-122, an abundant and conserved liver-specific miRNA, regulates hepatic metabolism and functions as a tumor suppressor, yet systematic and direct... 
BCL9 | gene regulation | miR-122 | Argonaute | HCC | Wnt | hepatocellular carcinoma | CLIP | HITS-CLIP | METASTASIS | GENE | MIRNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | HEPATOCELLULAR CARCINOMAS | IDENTIFICATION | EXPRESSION | MICRORNA TARGET SITES | RNA-BINDING PROTEIN | CELL BIOLOGY | Carcinoma, Hepatocellular - mortality | Cell Proliferation | Species Specificity | Exons | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Databases, Genetic | MicroRNAs - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Liver Neoplasms - mortality | Neoplasm Proteins - metabolism | Case-Control Studies | Transfection | RNA Interference | Time Factors | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Transcription, Genetic | 3' Untranslated Regions | Neoplasm Proteins - genetics | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Wnt Signaling Pathway | Argonaute Proteins - metabolism | Genome-Wide Association Study | Argonaute Proteins - genetics | Immunoprecipitation - methods | Liver Neoplasms - genetics | Down-Regulation | Computational Biology | Genotype | Mice, Knockout | Phenotype | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Mice | MicroRNAs - genetics | Transcription Factors | Carcinoma, Hepatocellular - metabolism | Medical research | Liver cancer | Cancer patients | Deregulation | Crosslinked polymers | Patient outcomes | Analysis | Genomics | Physiological aspects | Medicine, Experimental | Hepatitis C
Journal Article
Journal of Molecular Diagnostics, ISSN 1525-1578, 05/2018, Volume 20, Issue 3, pp. 277 - 278
This commentary highlights the article by Huang et al that reports a highly sensitive assay for detection of closed circular DNA of hepatitis B virus. 
INFECTION | PATHOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42192
..., Taipei, Taiwan Hui-Lung Sun Affiliation: Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan Ya-Ling Chang Affiliation... 
WILD-TYPE P53 | ACTIVATION | ONCOGENE | PROTEIN | THERAPY | PATHWAY | P73 FUNCTION | DNA | MULTIDISCIPLINARY SCIENCES | FLAVONOIDS | EXPRESSION | Transcription, Genetic - drug effects | Proto-Oncogene Proteins c-mdm2 - genetics | Apoptosis - drug effects | HCT116 Cells | Humans | Proto-Oncogene Proteins c-mdm2 - deficiency | Tumor Suppressor Protein p53 - metabolism | Male | Xenograft Model Antitumor Assays | Proteolysis - drug effects | Animals | Caspases - metabolism | Cell Cycle Checkpoints - drug effects | Caspases - biosynthesis | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Enzyme Induction - drug effects | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Flavonoids - pharmacology | Mice | Gene Expression Regulation, Neoplastic - drug effects | Proteasome Endopeptidase Complex - metabolism | Proto-Oncogene Proteins c-mdm2 - metabolism | Medicinal plants | Care and treatment | DNA damage | Medicine, Botanic | Cancer cells | Medicine, Herbal | Tumor proteins | Cancer | Apoptosis | Biotechnology | GTP-binding protein | Animal models | Toxicity | p53 Protein | Xenotransplantation | Lung cancer | Colorectal cancer | Genomes | Dephosphorylation | Kinases | Caspase-3 | Cancer therapies | Accumulation | Anticancer properties | Rodents | Penicillin | Xenografts | Cell cycle | Biocompatibility | Damage accumulation | Deoxyribonucleic acid--DNA | Medical research | MDM2 protein | Poly(ADP-ribose) polymerase | Retinoblastoma protein | Caspase | siRNA | Gene expression | Medicine | Herbal medicine | Flavonoids | Cell death | Caspase-9 | Hypoxia | Pharmaceuticals | Deoxyribonucleic acid
Journal Article
Carcinogenesis, ISSN 0143-3334, 01/2015, Volume 36, Issue 1, pp. 104 - 114
Journal Article
Journal Article