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International Journal of Nanomedicine, ISSN 1176-9114, 12/2016, Volume 11, pp. 6547 - 6559
Sustainable and safe delivery of brain-targeted drugs is highly important for successful therapy in Parkinson’s disease (PD). This study was designed to... 
Rotigotine | Brain targeting | Intranasal delivery | Lactoferrin-modified PEG-PLGA nanoparticles | Parkinson’s disease | Drugs | Nanoparticles | Proteins | Biomedical materials | Drug delivery systems | Dopamine | Brain research | Acids | Nervous system | Laboratory animals | Alzheimers disease
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 02/2018, Volume 13, pp. 705 - 718
Background: Safe and effective delivery of therapeutic drugs to the brain is important for successful therapy of Alzheimer’s disease (AD). Purpose: To develop... 
Nanoparticles | N-trimethyl chitosan | Lactoferrin | Alzheimer’s disease | Huperzine A | Nose-to-brain | Drug delivery systems | Laboratory animals | Alzheimers disease | Nose | Molecular weight
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2016, Volume 232, pp. 161 - 174
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 10/2017, Volume 34, Issue 10, pp. 2172 - 2184
To investigate the potential of a reduction-sensitive and fusogenic liposomes, enabled by surface-coating with chotooligosaccharides (COS) via a disulfide... 
Biochemistry, general | Biomedical Engineering | Biomedicine | Chotooligosaccharides (COS) | Cationic liposomes | Reduction-sensitivity | Pharmacy | Medical Law | Tumor-suppression | Cytoplasmic delivery | Survival rate | Pharmacology/Toxicology | RETENTION | CHITOSAN | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | CARRIER | NANOPARTICLES | IN-VITRO | THERAPEUTIC-EFFICACY | VASCULATURE | PHARMACOLOGY & PHARMACY | Osteosarcoma - drug therapy | Doxorubicin - therapeutic use | Humans | Male | Antineoplastic Agents - therapeutic use | Doxorubicin - chemistry | Drug Carriers | Drug Delivery Systems | Cholesterol - chemistry | Chitin - analogs & derivatives | Surface Properties | Doxorubicin - analogs & derivatives | Bone Neoplasms - drug therapy | Cell Survival | Drug Stability | Rats | Chitin - chemistry | Antineoplastic Agents - chemistry | Rats, Sprague-Dawley | Particle Size | Liposomes - chemistry | Animals | Mice, Nude | Cell Line, Tumor | Drug Liberation | Mice | Cytoplasm | Drugs | Drug delivery systems | Anthracyclines | Analysis | Physiological aspects | Drug therapy | Tumors | Vehicles | Flow cytometry | Animal models | Toxicity | Liver | Cytotoxicity | Confocal microscopy | Drug delivery | Confocal | Doxorubicin | Anticancer properties | Biomedical materials | Reduction | Antitumor agents | Osteosarcoma | Rodents | Biocompatibility | Dithiothreitol | Glutathione | Cell survival | Radioactive half-life | Reducing agents | Pharmacology | Osteosarcoma cells | Survival | Cholesterol | Cytometry | Microscopy | Hepatocytes | Zeta potential | Antitumor activity | Liposomes | Conjugation | Pharmacokinetics | Cancer
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 01/2017, Volume 34, Issue 1, p. 121
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s11095-016-2045-7 A... 
Drugs | Chemotherapy | Drug delivery systems | Peptides | Fluorescence | Methotrexate | Fluorescence microscopy | Vehicles | Cancer | Tumors | Pharmacology
Journal Article
NANOMEDICINE, ISSN 1743-5889, 04/2019, Volume 14, Issue 8, pp. 989 - 1009
Aim: This study aimed to explore the effect of nanoparticles loaded with exenatide in overcoming the mucus barrier and improving intestinal targeting... 
exenatide-Zn2 | NANOSCIENCE & NANOTECHNOLOGY | NANOCAPSULES | PEPTIDE | LMWP-DEX-PLGA | mucus penetration | INSULIN | targeted nanoparticle | IN-VITRO | TRANSPORT | PROTAMINE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | oral delivery | ENHANCEMENT | LOADED NANOPARTICLES | intestinal absorption | ABSORPTION | PROTEIN DELIVERY
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 3/2015, Volume 32, Issue 3, pp. 1017 - 1027
Exenatide, a potent insulinotropic agent, can be used for the treatment of non-insulin-dependent diabetes mellitus. However, the need for frequent injections... 
Biochemistry, general | Biomedical Engineering | goblet cell-targeting nanoparticles | Biomedicine | Pharmacy | in vivo image system | Medical Law | CSK peptide-modified chitosan | oral delivery system | Pharmacology/Toxicology | exenatide | DB/DB MICE | CHITOSAN | RECEPTOR | PHARMACODYNAMICS | CHEMISTRY, MULTIDISCIPLINARY | TRANSPORT | PHARMACOKINETICS | EXENDIN-4 | DRUGS | PHARMACOLOGY & PHARMACY | MUCUS | AGONIST | Humans | Peptides - pharmacokinetics | Male | Intestinal Absorption | Peptides - administration & dosage | Drug Carriers | Nanoparticles | Tissue Distribution | Hypoglycemic Agents - administration & dosage | Biotransformation | Venoms - administration & dosage | Nanomedicine | Oligopeptides - chemistry | Caco-2 Cells | Cell Survival - drug effects | Hypoglycemic Agents - pharmacokinetics | Peptides - chemistry | Administration, Oral | Technology, Pharmaceutical - methods | Hypoglycemic Agents - chemistry | Oligopeptides - metabolism | Oligopeptides - toxicity | Permeability | Goblet Cells - metabolism | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Blood Glucose - drug effects | HT29 Cells | Animals | Chitosan - chemistry | Venoms - chemistry | Blood Glucose - metabolism | Venoms - pharmacokinetics | Type 2 diabetes | Peptides | Therapeutics | Fluorescence | Hypoglycemic agents | Glucose | Dextrose | Homeopathy | Materia medica and therapeutics | Drug delivery systems | Diabetes | Pharmaceutical sciences | Index Medicus
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2018, Volume 25, Issue 1, pp. 900 - 908
An estrogen (ES)-functionalized cationic liposomal system was developed and exploited for targeted delivery to osteosarcoma. Natural biocompatible... 
targeting | chotooligosaccharides | Estrogen-functionalized | reduction-sensitivity | osteosarcoma | cationic liposomes | CELLS | OLIGOSACCHARIDES | DRUG-DELIVERY | CHITOSAN | NANOMEDICINE | TUMOR VASCULATURE | CANCER-THERAPY | REDUCTION | SENSITIVE LIPOSOMES | PHARMACOLOGY & PHARMACY | Polyethylene glycol | Cytotoxicity | Bone cancer | Index Medicus
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 02/2017, Volume 12, pp. 1353 - 1368
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 03/2018, Volume 13, pp. 1831 - 1840
Introduction: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted... 
Breast cancer | Fab’-modified curcumin nanoparticles | Pharmacokinetics | Trastuzumab-modified curcumin nanoparticles | Biodistribution | Tumour targeting | CANCER-CELLS | ANTI-HER2 IMMUNOLIPOSOMES | biodistribution | DESIGN | STRATEGY | DOXORUBICIN | tumour targeting | breast cancer | NANOSCIENCE & NANOTECHNOLOGY | ANTIBODY FRAGMENTS | pharmacokinetics | Fab'-modified curcumin nanoparticles | SINGLE-CHAIN FV | PHARMACOLOGY & PHARMACY | trastuzumab-modified curcumin nanoparticles | LIPOSOMES | TARGETED DELIVERY | Injections, Intravenous | Trastuzumab - therapeutic use | Curcumin - therapeutic use | Nanoparticles - chemistry | Trastuzumab - pharmacokinetics | Humans | Curcumin - pharmacokinetics | Nanoparticles - ultrastructure | Coumarins - chemistry | Polyethylene Glycols - chemistry | Curcumin - chemical synthesis | Rats, Sprague-Dawley | Tissue Distribution | Polyesters - chemistry | Endocytosis | Animals | Flow Cytometry | Immunoglobulin Fab Fragments - chemistry | Cell Death | Cell Line, Tumor | Female | Thiazoles - chemistry | Mice, Inbred BALB C | Microscopy, Fluorescence | Nanoparticles | Drugs | Antigens | Drug delivery systems | Epidermal growth factor | Liquid chromatography | Comparative analysis | Mass spectrometry | Fluorescence microscopy | Vehicles | Particle size | Immunoglobulins | Medical imaging | Proteins | Polyethylene glycol | Efficiency | Chemical bonds | Ligands | Polyvinyl alcohol | Laboratory animals | Tumors | Curcumin | Fab′-modified nanoparticles | Trastuzumab
Journal Article
Zhongguo fei ai za zhi = Chinese journal of lung cancer, ISSN 1009-3419, 09/2018, Volume 21, Issue 9, pp. 663 - 669
Afatinib, a second-generation irreversible epidermal growth factor inhibitor receptor for the development of non-small cell lung cancer and secondary drug... 
Particle size | Lung cancer | Mutation | Ultraviolet spectrophotometry | Ammonium sulfate gradient method | Liposomes | Afatinib | Determination of entrapment efficiency
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2012, Volume 29, Issue 9, pp. 2367 - 2376
Journal Article
Pharmaceutical development and technology, ISSN 1083-7450, 08/2019, pp. 1 - 7
Exenatide (EX), a glucagon-like peptide-1 receptor agonist, is used to treat diabetes mellitus. However, its short half-life necessitates frequent... 
Index Medicus
Journal Article