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British Journal of Ophthalmology, ISSN 0007-1161, 09/2019, Volume 103, Issue 9, pp. 1223 - 1227
BackgroundCataract is a major health burden in many countries and a significant problem in India. While observational studies show lower cataract risk with... 
ascorbate | epidemiology | genetics | lens and zonules | SLC23A1 | RISK | ASCORBIC-ACID | PLASMA | POLYMORPHISMS | EPITHELIAL-CELLS | ANTIOXIDANT | OPHTHALMOLOGY | RETINOL | LENS | ASSOCIATION | Index Medicus | Clinical Science | 1507 | 1506
Journal Article
Human molecular genetics, ISSN 0964-6906, 04/2019, Volume 28, Issue 15, pp. 2531 - 2548
LOXL1 (lysyl oxidase-like 1) has been identified as the major effect locus in pseudoexfoliation (PEX) syndrome, a fibrotic disorder of the extracellular matrix... 
General
Journal Article
Genetics in medicine : official journal of the American College of Medical Genetics, ISSN 1098-3600, 04/2019
Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide and mutations in known genes can only explain 5-6% of POAG. This... 
Journal Article
Ophthalmic Genetics, ISSN 1381-6810, 03/2019, Volume 40, Issue 2, pp. 185 - 187
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 07/2018, Volume 27, Issue 14, pp. 2563 - 2572
Abstract Retinitis pigmentosa (RP) refers to a group of retinal degenerative diseases, which often lead to vision loss. Although 70 genes have been identified... 
CRB1 | LIGAND-BINDING | GENE | INHERITED RETINAL DYSTROPHIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | AH-RECEPTOR | GENETICS & HEREDITY | MICE | PREVALENCE | POLYMORPHISM | IDENTIFICATION | DEGENERATION | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 07/2018, Volume 27, Issue 14, pp. 2587 - 2587
Journal Article
Journal Article
Journal of Clinical Neonatology, ISSN 2249-4847, 2018, Volume 7, Issue 1, p. 59
Journal Article
Current Eye Research, ISSN 0271-3683, 12/2017, Volume 42, Issue 12, pp. 1608 - 1613
Purpose: To compare the levels of cytokines and growth factor in aqueous humor of the patients with chronic primary angle closure glaucoma (PACG) and cataract.... 
cytokines | Aqueous humor | chemokines | chronic PACG | multiplex assay | EYES | NEURODEGENERATION | NECROSIS-FACTOR-ALPHA | CLONING | OPHTHALMOLOGY | INFLAMMATORY CYTOKINES | EXPRESSION | EOTAXIN | Aqueous Humor - metabolism | Cytokines - metabolism | Humans | Middle Aged | Glaucoma, Angle-Closure - metabolism | Immunoassay - methods | Female | Male | Aged | Cataract - metabolism | Chronic Disease | Index Medicus
Journal Article
Molecular Genetics & Genomic Medicine, 07/2017, Volume 5, Issue 4, pp. 323 - 335
Background Primary open‐angle glaucoma (POAG) is a complex disease of multigenic inheritance and the most common subtype of glaucoma. SIX6 encodes a... 
Glaucoma | Optic nerve | Pathogenesis | Zebrafish | Retina | Heredity | Single-nucleotide polymorphism | Gene deletion | Risk analysis | Assaying | Minority & ethnic groups | Population genetics | Risk factors | Haploinsufficiency | Thickness | Optical Coherence Tomography | Clonal deletion | Pituitary | Alleles | Deletion | Diagnostic systems
Journal Article
MOLECULAR GENETICS & GENOMIC MEDICINE, ISSN 2324-9269, 07/2017, Volume 5, Issue 4, pp. 323 - 335
Background Primary open-angle glaucoma (POAG) is a complex disease of multigenic inheritance and the most common subtype of glaucoma. SIX6 encodes a... 
TRANSCRIPTION FACTORS | COMMON VARIANTS | SUSCEPTIBILITY LOCI | Gene expression regulation | XENOPUS-LAEVIS | SIX6 | primary open-angle glaucoma | GENETICS & HEREDITY | zebrafish | TO-DISC RATIO | DIFFERENTIATION | 6 FAMILY | HOMEOBOX GENE | EXPRESSION | vertical cup to disc ratio | GENOME-WIDE ASSOCIATION
Journal Article
Molecular Genetics & Genomic Medicine, ISSN 2324-9269, 07/2017, Volume 5, Issue 4, pp. 323 - 335
We sequenced the SIX6 locus in a cohort of south Indian POAG patients and matched controls. We identified two known rare and two common variants in the SIX6... 
primary open‐angle glaucoma | Gene expression regulation | SIX | zebrafish | vertical cup to disc ratio | SIX6 | primary open-angle glaucoma
Journal Article