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1. Systems biology
: understanding the biological mosaic
by Russell, Robert and Superti-Furga, Giulio and Federation of European Biochemical Societies
2005, FEBS letters, Volume 579, no. 8 (Special issue), [1772]-1895.
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2. Le vicende politiche dal dominio straniero all'Italia unita
by Bonomi, Dino and Superti-Furga, Isabella
1979, Storia di Monza e della Brianza, Volume 2, 410 p., [20] leaves of plates
Monza (Italy) History | Brianza (Italy) History
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3. Molecular machines
by Feldmann, Horst and Superti-Furga, Giulio and Marlovits, Thomas C and Federation of European Biochemical Societies
2007, FEBS letters, Volume 581, no. 15 (Special issue), 2749-2876.
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4. Full Text Target profiling of small molecules by chemical proteomics
by Rix, Uwe and Superti-Furga, Giulio
Nature Chemical Biology, ISSN 1552-4450, 09/2009, Volume 5, Issue 9, pp. 616 - 624
The medical and pharmaceutical communities are facing a dire need for new druggable targets, while, paradoxically, the targets of some drugs that are in... 
PATEAMINE-A | EUKARYOTIC TRANSLATION INITIATION | BCR-ABL INHIBITORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | SPECTROMETRY-BASED PROTEOMICS | CODED AFFINITY TAGS | CELLULAR TARGETS | PROTEIN-KINASE INHIBITORS | MASS-SPECTROMETRY | ACTIVITY-BASED PROBES | Small Molecule Libraries - chemistry | Small Molecule Libraries - pharmacology | Biological Products - chemistry | Protein Kinase Inhibitors - chemistry | Drug Design | Protein Binding | Ligands | Biological Products - pharmacology | Protein Kinase Inhibitors - pharmacology | Proteomics - methods | Proteins | Prescription drugs | Biochemistry | Research | Molecular biology | Proteomics
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5. Full Text The authors reply
by Gori, Francesca and Superti-Furga, Andrea and Baron, Roland
New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 19, pp. 1902 - 1903
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6. Full Text Bone Formation and the Wnt Signaling Pathway REPLY
by Gori, F and Superti-Furga, A and Baron, R
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 11/2016, Volume 375, Issue 19, pp. 1902 - 1903
MEDICINE, GENERAL & INTERNAL
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7. Full Text Functional Dissection of Dynamic Molecular Networks in Innate Immunity
by Superti-Furga, Giulio
Biophysical Journal, ISSN 0006-3495, 01/2012, Volume 102, Issue 3, pp. 9a - 9a
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8. Full Text Cell biology: A key driver of therapeutic innovation
by Hantschel, O and Superti-Furga, G
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 2013, pp. 79 - 83
All processes associated with cellular function are likely to contribute to disease. Particularly in the cancer field, most major therapeutic innovations have... 
DRUG | SELECTIVE INHIBITOR | POLYCYTHEMIA-VERA | CHEMICAL PROTEOMICS | PHILADELPHIA-CHROMOSOME | BCR-ABL | TYROSINE KINASE JAK2 | MYELOPROLIFERATIVE NEOPLASMS | CLINICAL RESISTANCE | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY
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9. Full Text Genetic disorders of bone – An historical perspective
by Superti-Furga, Andrea and Unger, Sheila
Bone, ISSN 8756-3282, 09/2017, Volume 102, pp. 1 - 4
ACHONDROPLASIA | COLLAGEN GENE | LETHAL OSTEOGENESIS IMPERFECTA | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | GROWTH-FACTOR RECEPTOR-3 | CLASSIFICATION | MUTATIONS | DWARFISM | CONSTITUTIONAL DISORDERS | SKELETAL DISORDERS | Genetic Diseases, Inborn - diagnostic imaging | Bone Diseases - therapy | History, 21st Century | History, 20th Century | Humans | History, 19th Century | Bone Diseases - diagnostic imaging | Genetic Diseases, Inborn - pathology | Genetic Diseases, Inborn - therapy | Bone Diseases - pathology | Bone Diseases - history | Genetic Diseases, Inborn - history
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10. Full Text SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1
by Rebsamen, Manuele and Superti-Furga, Giulio
Autophagy, ISSN 1554-8627, 06/2016, Volume 12, Issue 6, pp. 1061 - 1062
The mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) acts as a crucial regulator of cellular metabolism by integrating growth... 
cancer | metabolism | solute carrier proteins | amino acid transport | MTOR | nutrient sensing | CELL BIOLOGY | Amino Acids - metabolism | Multiprotein Complexes - metabolism | Animals | Lysosomes - metabolism | TOR Serine-Threonine Kinases - metabolism | Models, Biological | Humans | Amino Acid Transport Systems - metabolism | Mechanistic Target of Rapamycin Complex 1
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11. Full Text After the grape rush: Sirtuins as epigenetic drug targets in neurodegenerative disorders
by Huber, Kilian and Superti-Furga, Giulio
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2011, Volume 19, Issue 12, pp. 3616 - 3624
Class III histone deacetylases (sirtuins) are becoming increasingly recognized as important epigenetic drug targets in cancer and metabolic disorders. As key... 
Sirtuins | Resveratrol | Huntington’s disease | Histone deacetylases | Alzheimer | Neurodegenerative disorders | Parkinson’s disease | Parkinson's disease | Huntington's disease | CHEMISTRY, MEDICINAL | DISEASE TRANSGENIC MICE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | NAD(+)-DEPENDENT HISTONE DEACETYLASES | DEPENDENT PROTEIN DEACETYLASES | PHOSPHATE SYNTHETASE 1 | CEREVISIAE LIFE-SPAN | FATTY-ACID OXIDATION | HUNTINGTONS-DISEASE | SMALL-MOLECULE ACTIVATORS | CALORIE RESTRICTION | Up-Regulation - drug effects | Stilbenes - therapeutic use | Epigenesis, Genetic | Humans | Enzyme Inhibitors - pharmacology | Alzheimer Disease - drug therapy | Parkinson Disease - drug therapy | Stilbenes - pharmacology | Neurodegenerative Diseases - drug therapy | Sirtuins - genetics | Enzyme Inhibitors - therapeutic use | Sirtuins - metabolism | Wine | Histone deacetylase | Neuroprotection | Neurodegenerative diseases | Data processing | SIRT1 protein | epigenetics | Signal transduction | Skin | Alzheimer's disease | Metabolic disorders | Movement disorders | Cancer
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12. Full Text Regulation of the c-Abl and Bcr-Abl tyrosine kinases
by Superti-Furga, Giulio and Hantschel, Oliver
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 01/2004, Volume 5, Issue 1, pp. 33 - 44
The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr-Abl fusion protein, causes... 
TRANSFORMING ABILITY | F-ACTIN | OLIGOMERIZATION DOMAIN | FUNCTIONAL INTERACTION | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | IN-VIVO | SRC FAMILY | PHOSPHORYLATION PATHWAYS | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY | Amino Acid Sequence | Phosphorylation | Proto-Oncogene Proteins c-abl - genetics | src-Family Kinases | Gene Expression Regulation - genetics | Protein-Tyrosine Kinases - metabolism | Humans | Proto-Oncogene Proteins c-abl - chemistry | Molecular Sequence Data | src Homology Domains | Sequence Homology, Amino Acid | Point Mutation | Fusion Proteins, bcr-abl - genetics | Protein-Tyrosine Kinases - genetics | Sequence Alignment | Animals | Protein-Tyrosine Kinases - chemistry | Proto-Oncogene Proteins c-abl - metabolism | Protein Conformation | Catalysis | Binding Sites | Fusion Proteins, bcr-abl - metabolism | Leukemia - genetics
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13. Full Text The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL
by Hantschel, Oliver and Grebien, Florian and Superti-Furga, Giulio
Cancer Research, ISSN 0008-5472, 10/2012, Volume 72, Issue 19, pp. 4890 - 4895
The BCR-ABL fusion kinase is the driving mutation of chronic myelogenous leukemias and is also expressed in a subset of acute lymphoblastic leukemias. Recent... 
KINASE-INHIBITOR | ACTIVE CONFORMATION | IMATINIB-RESISTANT | IN-VITRO | C-ABL | ONCOLOGY | TYROSINE KINASE | PHILADELPHIA-CHROMOSOME | CRYSTAL-STRUCTURE | CHRONIC MYELOID-LEUKEMIA | T315I MUTANT | Allosteric Site - genetics | Fusion Proteins, bcr-abl - chemistry | Protein Structure, Tertiary | Allosteric Site - drug effects | Humans | Models, Molecular | Binding, Competitive - drug effects | Fusion Proteins, bcr-abl - genetics | Adenosine Triphosphate - metabolism | Protein Binding - drug effects | Protein Kinase Inhibitors - pharmacology | Mutation | Fusion Proteins, bcr-abl - metabolism | Protein Kinase Inhibitors - metabolism
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14. Full Text Mass spectrometry-based functional proteomics: From molecular machines to protein networks
by Köcher, Thomas and Superti-Furga, Giulio
Nature Methods, ISSN 1548-7091, 10/2007, Volume 4, Issue 10, pp. 807 - 815
The study of protein-protein interactions by mass spectrometry is an increasingly important part of post-genomics strategies to understand protein function. A... 
TANDEM AFFINITY PURIFICATION | QUANTITATIVE PROTEOMICS | MINIMUM INFORMATION | BIOCHEMICAL RESEARCH METHODS | SMALL NUCLEAR RIBONUCLEOPROTEIN | POSTTRANSLATIONAL MODIFICATIONS | COMPLEX PURIFICATION | ABSOLUTE QUANTIFICATION | MAMMALIAN-CELLS | SACCHAROMYCES-CEREVISIAE | SYSTEMS BIOLOGY | Protein Interaction Mapping - methods | Validation Studies as Topic | Computers, Molecular | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Proteomics - methods | Proteins - isolation & purification | Mass Spectrometry - methods | Molecular biology | Mass spectrometry | Bioinformatics | Research methodology | Proteomics
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15. Full Text Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib
by Hantschel, Oliver and Rix, Uwe and Superti-Furga, Giulio
Leukemia & Lymphoma, ISSN 1042-8194, 2008, Volume 49, Issue 4, pp. 615 - 619
Following the initial success of imatinib as frontline therapy for chronic myeloid leukemia (CML), several second-generation therapeutics have been developed... 
drug targets | imatinib | chemical proteomics | BCR-ABL | Imatinib | Drug targets | Chemical proteomics | PHASE | ONCOLOGY | TYROSINE KINASE | RESISTANCE | KINASE INHIBITORS | MECHANISMS | HEMATOLOGY | CHRONIC MYELOID-LEUKEMIA | Dasatinib | Pyrimidines | Piperazines | Protein Kinase Inhibitors - therapeutic use | Humans | Fusion Proteins, bcr-abl - antagonists & inhibitors | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Thiazoles | Benzamides | Drug Delivery Systems - methods | Imatinib Mesylate
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16. Full Text A Call for Systematic Research on Solute Carriers
by César-Razquin, Adrián and Snijder, Berend and Frappier-Brinton, Tristan and Isserlin, Ruth and Gyimesi, Gergely and Bai, Xiaoyun and Reithmeier, Reinhart A and Hepworth, David and Hediger, Matthias A and Edwards, Aled M and Superti-Furga, Giulio
Cell, ISSN 0092-8674, 07/2015, Volume 162, Issue 3, pp. 478 - 487
Solute carrier (SLC) membrane transport proteins control essential physiological functions, including nutrient uptake, ion transport, and waste removal. SLCs... 
HUMAN PROTEOME | TRANSPORTER | HUMAN-CELLS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | BLOOD METABOLITES | MEMBRANE-PROTEINS | GENE-COEXPRESSION NETWORK | CRYO-EM STRUCTURE | MASS-SPECTROMETRY | CELL BIOLOGY | Gene Expression | Genetic Predisposition to Disease | Genome-Wide Association Study | Animals | Membrane Transport Proteins - genetics | Humans | Biomedical Research | Membrane Transport Proteins - metabolism | Drug Discovery | Membrane Transport Proteins - chemistry | Carrier proteins | Physiological aspects
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17. Full Text The Btk tyrosine kinase is a major target of the Bcr-Abi inhibitor dasatinib
by Hantschel, O and Rix, U and Schmidt, U and Burckstummer, T and Kneidinger, M and Schutze, G and Colinge, J and Bennett, KL and Ellmeier, WR and Valent, P and Superti-Furga, G
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2007, Volume 104, Issue 33, pp. 13283 - 13288
Dasatinib is a small-molecule kinase inhibitor used for the treatment of imatinib-resistant chronic myelogenous leukemia (CML). We have analyzed the kinases... 
leukemia | C-ABL | CHRONIC-PHASE | Tec kinases | MULTIDISCIPLINARY SCIENCES | X-LINKED AGAMMAGLOBULINEMIA | CRYSTAL-STRUCTURES | CHRONIC MYELOID-LEUKEMIA | kinase inhibitor | IN-VITRO | STRUCTURAL BASIS | IMATINIB | SELECTIVE INHIBITORS | STI-571 INHIBITION
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18. Differenzialdiagnose bei Kleinwuchs
by Zabel, B and Superti-Furga, A
Tagliche Praxis, ISSN 0494-464X, 09/2010, Volume 51, Issue 3, p. 598
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19. Full Text Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
by Klampfl, Thorsten and Gisslinger, Heinz and Gisslinger, Bettina and Harutyunyan, Ashot S and Nivarthi, Harini and Rumi, Elisa and Milosevic, Jelena D and Them, Nicole C.C and Berg, Tiina and Pietra, Daniela and Chen, Doris and Vladimer, Gregory I and Bagienski, Klaudia and Milanesi, Chiara and Casetti, Ilaria Carola and Sant'Antonio, Emanuela and Ferretti, Virginia and Elena, Chiara and Schischlik, Fiorella and Cleary, Ciara and Six, Melanie and Schalling, Martin and Schönegger, Andreas and Bock, Christoph and Malcovati, Luca and Pascutto, Cristiana and Superti-Furga, Giulio and Cazzola, Mario and Kralovics, Robert
The New England Journal of Medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 25, pp. 2379 - 2390
The authors identified calreticulin mutations in the majority of patients with essential thrombocythemia and myelofibrosis who did not have JAK2 mutations. The... 
MEDICINE, GENERAL & INTERNAL | POLYCYTHEMIA-VERA | GAIN-OF-FUNCTION | DISORDERS | COMPETING RISKS | PRIMARY MYELOFIBROSIS | ESSENTIAL THROMBOCYTHEMIA | JAK2 | PROGNOSTIC MODEL | PREDICT SURVIVAL | INTERNATIONAL WORKING GROUP | Primary Myelofibrosis - mortality | Exons | Humans | Leukemia, Myeloid - genetics | Janus Kinase 2 - genetics | Proportional Hazards Models | Thrombocythemia, Essential - genetics | Calreticulin - genetics | Sequence Analysis, DNA | Bone Marrow Diseases - genetics | Receptors, Thrombopoietin - genetics | Primary Myelofibrosis - genetics | Thrombosis - etiology | Thrombocythemia, Essential - mortality | Polymerase Chain Reaction | Mutation | Thrombocythemia, Essential - complications | Antibody diversity | Research | Health aspects | Myeloproliferative disorders | Myelofibrosis | Transcription | Medical treatment | Genes | Polycythemia vera | Stat5 protein | Thrombosis | Blood | Thrombopoietin | Calreticulin | Clonal deletion | Polycythemia | Janus kinase 2 | Janus kinase
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