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Journal of Neuroscience, ISSN 0270-6474, 07/2012, Volume 32, Issue 28, pp. 9457 - 9468
Acute stress reduces pain sensitivity by engaging an endocannabinoid signaling circuit in the midbrain. The neural mechanisms governing this process and... 
CANNABINOID RECEPTORS | PAIN MODULATION | DORSOLATERAL PERIAQUEDUCTAL GRAY | RAT | SYNAPSES | SYNAPTIC-TRANSMISSION | STIMULATION-PRODUCED ANALGESIA | ROSTRAL VENTROMEDIAL MEDULLA | STRESS-INDUCED ANALGESIA | NEUROSCIENCES | CB1 RECEPTORS | Cannabinoid Receptor Modulators - pharmacology | Analgesia - methods | Periaqueductal Gray - drug effects | Male | Receptors, Metabotropic Glutamate - metabolism | Pain - metabolism | RNA, Messenger - metabolism | Microscopy, Immunoelectron | Dose-Response Relationship, Drug | Protease Inhibitors - pharmacology | Tandem Mass Spectrometry | Arachidonic Acids - metabolism | Electroconvulsive Therapy - methods | Synapses - metabolism | Piperidines - pharmacology | Pain - drug therapy | Receptor, Metabotropic Glutamate 5 | Lipoprotein Lipase - metabolism | Endocannabinoids | Pyrazoles - pharmacology | Cannabinoid Receptor Modulators - agonists | Rats | Synapses - ultrastructure | Excitatory Amino Acid Antagonists - pharmacology | Cyclohexanones - pharmacology | Glycerides - metabolism | Pain - pathology | Rats, Sprague-Dawley | Periaqueductal Gray - metabolism | Methoxyhydroxyphenylglycol - analogs & derivatives | Receptor, Cannabinoid, CB1 - metabolism | Animals | Analysis of Variance | RNA, Small Interfering - therapeutic use | Cannabinoid Receptor Modulators - antagonists & inhibitors | Mice | Pyridines - pharmacology | Methoxyhydroxyphenylglycol - administration & dosage
Journal Article
Neuropharmacology, ISSN 0028-3908, 2005, Volume 49, Issue 8, pp. 1201 - 1209
Recent research in our laboratory has demonstrated that stress activates an endogenous cannabinoid mechanism that suppresses sensitivity to pain [Nature 435... 
Fatty acid amide hydrolase | Periaqueductal gray | Rostral ventromedial medulla | Cannabinoid | Stress-induced analgesia | Anandamide | RAT | NEURONS IN-VITRO | cannabinoid | ENDOCANNABINOID SYSTEM | NON-OPIOID MECHANISMS | rostral ventromedial medulla | NEUROSCIENCES | stress-induced analgesia | fatty acid amide hydrolase | PAIN | CROSS-TOLERANCE | PHARMACOLOGY & PHARMACY | RECEPTOR AGONIST | anandamide | periaqueductal gray | MODULATION | INDUCED ANTINOCICEPTION | Capsaicin - pharmacology | Cannabinoids - antagonists & inhibitors | Cytosol - drug effects | Periaqueductal Gray - drug effects | Male | TRPV Cation Channels - drug effects | Phospholipases A - metabolism | Phospholipases A2 | Stress, Psychological - psychology | Polyunsaturated Alkamides | Cytosol - enzymology | Arachidonic Acids - metabolism | Piperidines - pharmacology | Medulla Oblongata - physiology | Endocannabinoids | Carrier Proteins | Pyrazoles - pharmacology | Microinjections | Medulla Oblongata - drug effects | Receptor, Cannabinoid, CB2 - drug effects | Rats | Amidohydrolases - antagonists & inhibitors | Capsaicin - analogs & derivatives | Pain Measurement - drug effects | Rats, Sprague-Dawley | Cannabinoids - pharmacology | Analgesia | Animals | Receptor, Cannabinoid, CB1 - drug effects | Periaqueductal Gray - physiology | Mice | Hydrolysis | Enzymes | Hydrolases | Neurosciences | Analysis
Journal Article
Neuropharmacology, ISSN 0028-3908, 2006, Volume 50, Issue 3, pp. 372 - 379
Recent work in our laboratories has demonstrated that an opioid-independent form of stress-induced analgesia (SIA) is mediated by endogenous cannabinoids... 
Fatty-acid amide hydrolase | Periaqueductal gray | Monoacylglycerol lipase | Endocannabinoid | Stress antinociception | 2-Arachidonoylglycerol | Rostral ventromedial medulla | Anandamide | Dorsal horn | monoacylglycerol lipase | endocannabinoid | dorsal horn | NON-OPIOID MECHANISMS | rostral ventromedial medulla | fatty-acid amide hydrolase | DYNAMIC-RANGE NEURONS | NEUROSCIENCES | 2-arachidonoylglycerol | CB1 RECEPTOR | stress antinociception | LUMBAR DORSAL-HORN | ACID AMIDE HYDROLASE | IN-VIVO | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | anandamide | CANNABINOID-INDUCED ANTINOCICEPTION | ANANDAMIDE AMIDOHYDROLASE | periaqueductal gray | Spinal Cord - drug effects | Spinal Cord - metabolism | Male | Serotonin - pharmacology | Stress, Psychological - psychology | Behavior, Animal | Dose-Response Relationship, Drug | Polyunsaturated Alkamides | Arachidonic Acids - metabolism | Drug Interactions | Piperidines - pharmacology | Time Factors | Reaction Time - drug effects | Stress, Psychological - metabolism | Benzamides - pharmacology | Endocannabinoids | Carbamates - pharmacology | Pyrazoles - pharmacology | Rats | Glycerides - metabolism | Rats, Sprague-Dawley | Arachidonic Acids - pharmacology | Analgesia | Pain Measurement - methods | Animals | Analysis of Variance | Serotonin - analogs & derivatives | Mass Spectrometry - methods | Hydrolysis | Lipase
Journal Article
Journal Article
2008, ISBN 9780387766775
Cannabinoids are antinociceptive in animal models of acute, tissue injury—, and nerve injury—induced nociception. This review examines the biology of... 
Pharmacology/Toxicology | Biomedicine | monoacylglycerol lipase | CB1 | fatty acid amide hydrolase | rostral ventromedial medulla | anandamide | 2-arachidonoylglycerol | periaqueductal gray
Book Chapter
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