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index medicus (9) 9
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Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2018, Volume 18, Issue 12, pp. 1702 - 1710
Background: The anti-mitotic activity of podophyllotoxin derivative targeting tubulin enzyme proved them as strong polymerization inhibitors. The introduction... 
Tubulin inhibitor | One-pot synthesis | Heterolignan | Anti-proliferative | Cycloaddition | Molecular docking | CHEMISTRY, MEDICINAL | anti-proliferative | cycloaddition | molecular docking | STEGANACIN | tubulin inhibitor | ONCOLOGY | PROPARGYLIC ALCOHOLS | PODOPHYLLOTOXIN | one-pot synthesis | DERIVATIVES | ACCESS
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2019, Volume 29, Issue 20, p. 126671
[Display omitted] Towards a quest for establishing new antitubercular agents, we have designed new quinoline–triazole hybrid analogs in a six-step reaction... 
Quinoline | Single crystal X-ray diffraction | 1,2,3-Triazole | Mycobacterium tuberculosis | Antimycobacterial activity | Cytotoxicity studies | DESIGN | CHEMISTRY, MEDICINAL | CLICK CHEMISTRY | CHEMISTRY, ORGANIC | BEDAQUILINE | LEADS | HYBRIDS
Journal Article
Biochimica et biophysica acta. Molecular cell research, ISSN 0167-4889, 2019, Volume 1866, Issue 8, pp. 1298 - 1309
Tumor protein D52 (TPD52) is overexpressed in multiple cancers including prostate cancer due to gene amplification and investigations to understand its role in... 
Peroxiredoxin 1 (PRDX1) | Tumor protein D52 (TPD52) | Prostate cancer | Proto-oncogene | Protein-protein interactions | TPD52 | ANDROGEN RECEPTOR | APOPTOSIS | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | FAMILY | CELL BIOLOGY | REGULATOR | OVEREXPRESSION | GENE | HYDROGEN-PEROXIDE
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 92, pp. 501 - 513
Journal Article
The FEBS journal, ISSN 1742-464X, 09/2014, Volume 281, Issue 18, pp. 4240 - 4248
Journal Article
ACS combinatorial science, ISSN 2156-8952, 04/2019, Volume 21, Issue 4, pp. 241 - 256
Dimethylarginine dimethylaminohydrolase1 (DDAH1) inhibitors are important therapeutics by virtue of their ability to control nitric oxide (NO) production by... 
dimethylarginine dimethylaminohydrolase-1 | tumor growth inhibition | angiogenesis | asymmetric dimethylarginine | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE | CHEMISTRY, MEDICINAL | ASSAY | METASTASIS | NITRIC-OXIDE SYNTHASE | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | THERAPY | ANTI-ANGIOGENESIS | CHEMISTRY, APPLIED | CANCER PROGRESSION | EXPRESSION | Prostatic Neoplasms - metabolism | Pyridines - chemistry | Humans | Male | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Arginine - analogs & derivatives | Antineoplastic Agents - metabolism | DNA-Binding Proteins - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Enzyme Inhibitors - chemistry | Prostatic Neoplasms - drug therapy | Pyridines - therapeutic use | Prostatic Neoplasms - blood supply | Cell Survival - drug effects | Prostatic Neoplasms - pathology | Enzyme Inhibitors - metabolism | Signal Transduction | Amidohydrolases - antagonists & inhibitors | Antineoplastic Agents - chemistry | Enzyme Inhibitors - therapeutic use | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Pyridines - metabolism | Mice, Nude | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Chemokines - metabolism | Molecular Docking Simulation | Nitric Oxide - metabolism | Arginine - metabolism | Drug Screening Assays, Antitumor | Nitric Oxide Synthase Type II - metabolism
Journal Article
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