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Nature reviews. Drug discovery, ISSN 1474-1784, 02/2008, Volume 7, Issue 2, pp. 168 - 181
Journal Article
Journal of enzyme inhibition and medicinal chemistry, ISSN 1475-6374, 04/2012, Volume 27, Issue 6, pp. 759 - 772
Inhibition of the metalloenzyme carbonic anhydrase (CA; EC 4.2.1.1) has pharmacologic applications in the field of anti-glaucoma, anti-convulsant and... 
sulphonamide | x-ray crystallography | imaging of hypoxic tumours | Carbonic anhydrase | glaucoma | anti-cancer agent | dithiocarbamate | Glaucoma | X-ray crystallography | Anti-cancer agent | Dithiocarbamate | Sulphonamide | Imaging of hypoxic tumours | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Fungal Proteins - chemistry | Anti-Infective Agents - pharmacology | Humans | Bacteria - drug effects | Bacterial Proteins - chemistry | Crystallography, X-Ray | Fungal Proteins - antagonists & inhibitors | Isoenzymes - chemistry | Structure-Activity Relationship | Carbonic Anhydrases - chemistry | Carbonic Anhydrases - metabolism | Bacteria - growth & development | Thiocarbamates - pharmacology | Isoenzymes - metabolism | Fungi - growth & development | Bacterial Proteins - antagonists & inhibitors | Catalytic Domain | Fungi - drug effects | Carbonic Anhydrase Inhibitors - chemical synthesis | Carbonic Anhydrase Inhibitors - pharmacology | Sulfonamides - pharmacology | Drug Discovery | Anti-Infective Agents - chemical synthesis | Sulfonamides - chemical synthesis | Thiocarbamates - chemical synthesis | Bacterial Proteins - metabolism | Molecular Docking Simulation | Isoenzymes - antagonists & inhibitors | Fungal Proteins - metabolism | Index Medicus
Journal Article
Journal of enzyme inhibition and medicinal chemistry, ISSN 1475-6374, 02/2018, Volume 33, Issue 1, pp. 485 - 495
A set of compounds incorporating carbon-based zinc-binding groups (ZBGs), of the type PhX (X = COOH, CONH 2 , CONHNH 2 , CONHOH, CONHOMe), and the... 
zinc binder | inhibitors | sulphonamide | inhibition mechanism | Carbonic anhydrase | anchoring to zinc-coordinated water | hydroxamate | carboxylate | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Index Medicus
Journal Article