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Journal of Gastroenterology, ISSN 0944-1174, 05/2018, Volume 53, Issue 5, pp. 618 - 630
Curcumin, a pleiotropic substance used for centuries in traditional medicine, exhibits antioxidant, anti-inflammatory and antiproliferative efficacy against... 
Transient potential vanilloid receptor | Prostaglandin | Nitric oxide | Gastrin | Afferent sensory fibres | Gastric blood flow | Calcitonin gene related peptide | Curcumin | ULCERS | AFFERENT NEURONS | GENE-RELATED PEPTIDE | CYCLOOXYGENASE-2 | RAT | INJURY | REACTIVE-OXYGEN | PROSTAGLANDINS | NITRIC-OXIDE | SENSORY NERVES | GASTROENTEROLOGY & HEPATOLOGY | Superoxide Dismutase - genetics | Gene Expression - drug effects | Rats, Wistar | Capsaicin - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Stomach Diseases - chemically induced | Gastric Mucosa - pathology | Male | Gastric Mucosa - metabolism | RNA, Messenger - metabolism | Sulfones - pharmacology | CDX2 Transcription Factor - genetics | Lactones - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Regional Blood Flow - drug effects | TRPV Cation Channels - antagonists & inhibitors | Female | Stomach Diseases - prevention & control | Calcitonin Gene-Related Peptide - metabolism | Heme Oxygenase (Decyclizing) - genetics | Gastric Mucosa - blood supply | Pyrazoles - pharmacology | Gastrins - blood | Curcumin - therapeutic use | Cyclooxygenase 2 Inhibitors - pharmacology | Ethanol | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Curcumin - pharmacology | Rats | Capsaicin - analogs & derivatives | Down-Regulation - drug effects | Indomethacin - pharmacology | Up-Regulation - drug effects | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Nitric Oxide - metabolism | Denervation | Prostaglandins - metabolism | Antioxidants | COX-2 inhibitors | Prostaglandins | Alcohol, Denatured | RNA | Alcohol | Substance abuse | Rofecoxib | Capsaicin | Mucosa | Capsaicin receptors | Inflammation | Gene expression | Capsazepine | Blood flow | Prostaglandin endoperoxide synthase | Polymerase chain reaction | Calcitonin gene-related peptide | Cyclooxygenase-1 | Arginine | Radioimmunoassay | Rodents | Sensory neurons | Indomethacin | Cyclooxygenase-2 | Tumors | Original —Alimentary Tract
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0140493
The physiological gaseous molecule, carbon monoxide (CO) becomes a subject of extensive investigation due to its vasoactive activity throughout the body but... 
GUANYLATE-CYCLASE ACTIVATION | INHIBITION | OXIDATIVE DAMAGE | PATHWAY | MULTIDISCIPLINARY SCIENCES | NITRIC-OXIDE | MUCOSAL DEFENSE | RATS | HEME OXYGENASE-1/CARBON MONOXIDE | STRESS | EXPRESSION | Heme Oxygenase-1 - metabolism | Rats, Wistar | Protoporphyrins - pharmacology | Gastric Mucosa - pathology | Male | Chromatography, Gas | Interleukin-1beta - genetics | Carbon Monoxide - metabolism | Gastric Mucosa - metabolism | RNA, Messenger - metabolism | Heme Oxygenase-1 - genetics | Carboxyhemoglobin - metabolism | Interleukin-1beta - metabolism | Protective Agents - pharmacology | Gastric Mucosa - drug effects | Heme Oxygenase (Decyclizing) - metabolism | Stomach - drug effects | Stomach - pathology | Ethanol | RNA, Messenger - genetics | Stomach - blood supply | Regional Blood Flow | Animals | Nitric Oxide Synthase Type II - genetics | NF-E2-Related Factor 2 - metabolism | Stomach - enzymology | Cyclooxygenase 2 - metabolism | Organometallic Compounds - pharmacology | Nitric Oxide Synthase Type II - metabolism | COX-2 inhibitors | Oxidative stress | Mucosa | Gastric mucosa | Carboxyhemoglobin | Kinases | Guanylate cyclase | Blood | Prostaglandin endoperoxide synthase | Proteins | Interleukin 4 | Prostaglandins | Ischemia | Vasoactive agents | Rodents | Cyclic GMP | Heme | Physiology | Pretreatment | Carbon monoxide | Lesions | NRF2 protein | Antiinflammatory agents | Cytokines | Inflammation | Celecoxib | Gene expression | Nitric-oxide synthase | Zinc | Blood flow | Gas chromatography | Hemin | Cyclooxygenase-1 | Nitric oxide | Hypoxia | Indomethacin | Diabetes | Cyclooxygenase-2 | Endoplasmic reticulum
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0118972
Hydrogen sulfide (H2S) plays an important role in human physiology, exerting vasodilatory, neuromodulatory and anti-inflammatory effects. H2S has been... 
PATHOGENESIS | MUCOSA | INHIBITION | LIPID-PEROXIDATION | ULCERATION | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | RESOLUTION | INJURY | DAMAGE | NEUROPEPTIDES | Stomach - physiopathology | Glycine - analogs & derivatives | Sensory Receptor Cells - pathology | Rats, Wistar | Stomach - immunology | Sensory Receptor Cells - immunology | Stomach - blood supply | Stress, Physiological | Gastric Mucosa - innervation | Male | Gastric Mucosa - immunology | Glycine - immunology | Animals | Prostaglandins - immunology | Calcitonin Gene-Related Peptide - immunology | Gastric Mucosa - physiopathology | Stomach - innervation | Cyclooxygenase 2 - immunology | Hydrogen Sulfide - immunology | Cyclooxygenase 1 - immunology | Alkynes - immunology | Cysteine - immunology | Gastric Mucosa - blood supply | Hydrogen sulfide | COX-2 inhibitors | Enzymes | Cysteine | Prostaglandins | RNA | Analysis | Physiological aspects | Indomethacin | Sulfide | Rofecoxib | Capsaicin | Hydrogen | Mucosa | Gastric mucosa | Capsaicin receptors | Hemorrhage | Neuromodulation | Prostaglandin endoperoxide synthase | Proteins | Receptors | Ischemia | Rodents | Calcitonin | Gastroenterology | Nerves | Sensory neurons | Tumor necrosis factor-TNF | Physiology | Pretreatment | Nonsteroidal anti-inflammatory drugs | Lesions | Drug dosages | Hydrogen ion concentration | Stresses | Medical research | Water immersion | Rats | Inflammation | Gene expression | Capsazepine | Stress | Blood flow | Calcitonin gene-related peptide | Cyclooxygenase-1 | Ulcers | Hyperemia | Cyclooxygenase-2 | Denervation
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 11/2016, Volume 61, Issue 11, pp. 3176 - 3189
Alendronate is an inhibitor of osteoclast-mediated bone resorption, but its clinical utility is limited due to gastrointestinal complications including... 
Biochemistry, general | Hydrogen sulfide | Gastroprotection | Hypoxia-inducible factor-1α | Medicine & Public Health | Alendronate | Hepatology | Gastroenterology | Oncology | Gastric blood flow | Carbon monoxide | Transplant Surgery | PHYSIOLOGY | NITROGEN-CONTAINING BISPHOSPHONATE | INDUCIBLE FACTOR-I | LIPID-PEROXIDATION | MECHANISM | RAT | Hypoxia-inducible factor-1 alpha | NITRIC-OXIDE SYNTHASE | HYPOXIA | DAMAGE | ISCHEMIA-REPERFUSION INJURY | GASTROENTEROLOGY & HEPATOLOGY | Hypoxia-Inducible Factor 1, alpha Subunit - drug effects | Interleukin-1beta - drug effects | Superoxide Dismutase - genetics | Rats, Wistar | Gastric Mucosa - pathology | Male | Interleukin-1beta - genetics | Gastric Mucosa - metabolism | RNA, Messenger - metabolism | Gasotransmitters - pharmacology | Carbon Monoxide - pharmacology | Cyclooxygenase 2 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Protective Agents - pharmacology | Gastric Mucosa - drug effects | Glutathione Peroxidase - drug effects | Heme Oxygenase (Decyclizing) - drug effects | Heme Oxygenase (Decyclizing) - genetics | Real-Time Polymerase Chain Reaction | RNA, Messenger - drug effects | Sulfides - pharmacology | Hydrogen Sulfide - pharmacology | Vasodilator Agents - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Nitric Oxide Synthase Type II - drug effects | Rats | Cyclooxygenase 2 - drug effects | Superoxide Dismutase - drug effects | Blotting, Western | Glutathione Peroxidase - genetics | Bone Density Conservation Agents - pharmacology | Animals | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Alendronate - pharmacology | Stress, Psychological | Organometallic Compounds - pharmacology | NF-kappa B - drug effects | Vasodilators | Analysis | Gastrointestinal diseases
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 03/2016, Volume 17, Issue 4, pp. 442 - 442
Carbon monoxide (CO) produced by heme oxygenase (HO)-1 and HO-2 or released from the CO-donor, tricarbonyldichlororuthenium (II) dimer (CORM-2) causes... 
Gastroprotection | Nitric oxide | Soluble guanylyl cyclase | Heme oxygenase-1 | Cyclooxygenases | Gastric blood flow | Hypoxia inducible factor 1α | Carbon monoxide | Stress | stress | hypoxia inducible factor 1 alpha | nitric oxide | ISCHEMIA/REPERFUSION INJURY | OXIDATIVE STRESS | GUANYLATE-CYCLASE ACTIVATION | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | carbon monoxide | heme oxygenase-1 | HYDROGEN-SULFIDE | CHEMISTRY, MULTIDISCIPLINARY | DAMAGE | INHIBITION | soluble guanylyl cyclase | gastric blood flow | PATHWAY | cyclooxygenases | gastroprotection | EXPRESSION | PROSTAGLANDIN E-2 | Rats, Wistar | Protoporphyrins - pharmacology | Stress, Physiological | Male | Carbon Monoxide - metabolism | Gastric Mucosa - metabolism | RNA, Messenger - metabolism | Cyclooxygenase 2 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Gastric Mucosa - drug effects | Hemin - pharmacology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Heme Oxygenase (Decyclizing) - genetics | Pyrazoles - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Rats | Celecoxib - pharmacology | Indomethacin - pharmacology | Nitroarginine - pharmacology | Animals | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Carbon Monoxide - blood | Organometallic Compounds - chemistry | Nitric Oxide - metabolism | Organometallic Compounds - pharmacology | Nitric Oxide Synthase Type II - metabolism | Molecules | Oxygen therapy | Pathogenesis | Gastrointestinal diseases | hypoxia inducible factor 1α
Journal Article
Nutrients, ISSN 2072-6643, 04/2017, Volume 9, Issue 4, p. 410
Inflammatory bowel diseases (IBDs) are a heterogeneous group of disorders exhibited by two major phenotypic forms: Crohn's disease and ulcerative colitis.... 
Myokines | Irisin | Diet-induced obesity | Colonic blood flow | Inflammation | Voluntary exercise | Colitis | Tumour necrosis factor-alpha | Adiponectin | Interleukin-6 | colonic blood flow | adiponectin | colitis | CROHNS-DISEASE | voluntary exercise | ULCERATIVE-COLITIS | CREEPING FAT | myokines | CYTOKINE EXPRESSION | diet-induced obesity | interleukin-6 | NUTRITION & DIETETICS | INFLAMMATORY-BOWEL-DISEASE | inflammation | AUTOIMMUNE-DISEASES | INSULIN-RESISTANCE | MOUSE MODEL | MESENTERIC ADIPOSE-TISSUE | PHYSICAL-ACTIVITY | irisin | tumour necrosis factor-alpha | Mice, Inbred C57BL | Tumor Necrosis Factor-alpha - blood | Male | Biomarkers - blood | Chemokine CCL2 - blood | Fibronectins - blood | Colon - metabolism | Interleukin-1beta - blood | Adiponectin - blood | Animals | Leptin - blood | Adiposity | Colitis - therapy | Colitis - blood | Interleukin-6 - blood | Colitis - chemically induced | Diet, High-Fat | Mice | Interleukin-13 - blood | Physical Conditioning, Animal | Disease Models, Animal | Wheel running | Inflammatory bowel diseases | Adipose tissue | Physical training | Physical activity | Pathogenesis | Disorders | High fat diet | Interleukin 6 | Exercise | Restoration | Intestine | Cerebral blood flow | Rodents | Tumor necrosis factor-TNF | Colon | Lesions | Cytokines | Muscles | Interleukin 13 | Skeletal muscle | Blood flow | Inflammatory bowel disease | Polymerase chain reaction | Physical fitness | Tumor necrosis factor | Leptin | Biomarkers | Plasma levels | Monocyte chemoattractant protein 1 | Plasmas (physics) | Ulcerative colitis | Tumors
Journal Article
NUTRIENTS, ISSN 2072-6643, 05/2019, Volume 11, Issue 5, p. 1127
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 03/2014, Volume 15, Issue 3, pp. 4946 - 4964
Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide (NO) synthesis inhibitor and pro-inflammatory factor. We investigated the role of ADMA in rat... 
Asymmetric dimethyl arginine | Calcitonin gene-related peptide | Farnesoid X receptor | Capsaicin | Gastric mucosa | Gastric damage | Sensory neurons | Ischemia/reperfusion | gastric mucosa | ISCHEMIA/REPERFUSION INJURY | farnesoid X receptor | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | RATS | calcitonin gene-related peptide | sensory neurons | CHEMISTRY, MULTIDISCIPLINARY | DAMAGE | asymmetric dimethyl arginine | ischemia | SYNTHASE INHIBITOR | PROSTAGLANDINS | MUCOSAL INJURY | capsaicin | L-ARGININE | SENSORY NERVES | ENDOGENOUS METHYLARGININES | reperfusion | gastric damage | Enzyme-Linked Immunosorbent Assay | Rats, Wistar | Calcitonin Gene-Related Peptide - pharmacology | Capsaicin - pharmacology | Tumor Necrosis Factor-alpha - blood | Interleukin-10 - blood | Male | Stomach Diseases - etiology | Stomach Diseases - metabolism | Gastric Mucosa - metabolism | Arginine - analogs & derivatives | Isoxazoles - pharmacology | Animals | Drug Interactions | Arginine - blood | Arginine - pharmacology | Malondialdehyde - blood | Gastric Mucosa - drug effects | Calcitonin Gene-Related Peptide - blood | Reperfusion Injury - complications | Stomach Diseases - prevention & control | Nitric Oxide - metabolism | Blood Flow Velocity - drug effects | Gastric Mucosa - blood supply | Plasma | Biosynthesis | Peptides | Pathogenesis | Neurons | Nitric oxide | ischemia/reperfusion
Journal Article