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1. Full Text Minimal residual disease monitoring: a new era for childhood ALL
by Schnittger, Susanne
The lancet oncology, ISSN 1470-2045, 2015, Volume 16, Issue 4, pp. 362 - 364
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Neoplasm, Residual - drug therapy | Neoplasm Recurrence, Local - drug therapy | Female | Male | Index Medicus
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2. Full Text Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A European LeukemiaNet Study
by Daniela Cilloni and Aline Renneville and Fabienne Hermitte and Robert K. Hills and Sarah Daly and Jelena V. Jovanovic and Enrico Gottardi and Milena Fava and Susanne Schnittger and Tamara Weiss and Barbara Izzo and Josep Nomdedeu and Adrian van der Heijden and Bert A. van der Reijden and Joop H. Jansen and Vincent H.J. van der Velden and Hans Ommen and Claude Preudhomme and Giuseppe Saglio and David Grimwade
Journal of clinical oncology, ISSN 0732-183X, 11/2009, Volume 27, Issue 31, pp. 5195 - 5201
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Prognosis | Gene Expression - drug effects | Humans | Middle Aged | Risk Factors | Child, Preschool | Neoplasm, Residual - genetics | Young Adult | Leukemia, Myeloid, Acute - diagnosis | Genes, Wilms Tumor | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | DNA Mutational Analysis | Reverse Transcriptase Polymerase Chain Reaction - methods | Adolescent | Leukemia, Myeloid, Acute - drug therapy | Adult | Aged | Biomarkers, Tumor - genetics | Child | Leukemia, Myeloid, Acute - genetics | Index Medicus
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3. Full Text Prognostic relevance of FLT3-TKD mutations in AML: The combination matters an analysis of 3082 patients
by Bacher, Ulrike and Haferlach, Claudia and Kern, Wolfgang and Haferlach, Torsten and Schnittger, Susanne
Blood, ISSN 0006-4971, 03/2008, Volume 111, Issue 5, pp. 2527 - 2537
Life Sciences & Biomedicine | Hematology | Science & Technology | Protein Structure, Tertiary | Recurrence | Prognosis | Leukemia, Myeloid, Acute - pathology | Humans | Middle Aged | Survival Rate | Genetic Markers | Mutation - genetics | fms-Like Tyrosine Kinase 3 - chemistry | Leukemia, Myeloid, Acute - mortality | fms-Like Tyrosine Kinase 3 - genetics | Thermodynamics | Leukemia, Myeloid, Acute - diagnosis | DNA Mutational Analysis | Karyotyping | Adolescent | Aged, 80 and over | Adult | Aged | Neoplasm Proteins - genetics | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
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4. Full Text Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
by Schnittger, Susanne and Schoch, Claudia and Kern, Wolfgang and Mecucci, Cristina and Tschulik, Claudia and Martelli, Massimo F and Haferlach, Torsten and Hiddemann, Wolfgang and Falini, Brunangelo
Blood, ISSN 0006-4971, 12/2005, Volume 106, Issue 12, pp. 3733 - 3739
Life Sciences & Biomedicine | Hematology | Science & Technology | Prognosis | Humans | Middle Aged | Male | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | DNA Mutational Analysis | Adolescent | Survival Analysis | Aged, 80 and over | Adult | Female | Aged | Mutation | Nuclear Proteins - genetics | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
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5. Full Text Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia
by Raphaël Itzykson and Olivier Kosmider and Aline Renneville and Véronique Gelsi-Boyer and Manja Meggendorfer and Margot Morabito and Céline Berthon and Lionel Adès and Pierre Fenaux and Odile Beyne-Rauzy and Norbert Vey and Thorsten Braun and Torsten Haferlach and François Dreyfus and Nicholas C.P. Cross and Claude Preudhomme and Olivier A. Bernard and Michaela Fontenay and William Vainchenker and Susanne Schnittger and Daniel Birnbaum and Nathalie Droin and Eric Solary
Journal of clinical oncology, ISSN 0732-183X, 07/2013, Volume 31, Issue 19, pp. 2428 - 2436
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Leukemia, Myelomonocytic, Chronic - diagnosis | Predictive Value of Tests | Prognosis | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Protein Splicing - genetics | Gene Expression Profiling | Adult | Female | Neoplasm Proteins - genetics | Risk Assessment | Leukemia, Myelomonocytic, Chronic - mortality | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Repressor Proteins - genetics | Genotype | Signal Transduction - genetics | Phenotype | Analysis of Variance | Epigenesis, Genetic - genetics | Aged | Mutation | Index Medicus
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6. Full Text BRAF Mutations in Hairy-Cell Leukemia
by Tiacci, Enrico and Trifonov, Vladimir and Schiavoni, Gianluca and Holmes, Antony and Kern, Wolfgang and Martelli, Maria Paola and Pucciarini, Alessandra and Bigerna, Barbara and Pacini, Roberta and Wells, Victoria A and Sportoletti, Paolo and Pettirossi, Valentina and Mannucci, Roberta and Elliott, Oliver and Liso, Arcangelo and Ambrosetti, Achille and Pulsoni, Alessandro and Forconi, Francesco and Trentin, Livio and Semenzato, Gianpietro and Inghirami, Giorgio and Capponi, Monia and Di Raimondo, Francesco and Patti, Caterina and Arcaini, Luca and Musto, Pellegrino and Pileri, Stefano and Haferlach, Claudia and Haferlach, Torsten and Schnittger, Susanne and Pizzolo, Giovanni and Foà, Robin and Farinelli, Laurent and Pasqualucci, Laura and Rabadan, Raul and Falini, Brunangelo
The New England journal of medicine, ISSN 0028-4793, 06/2011, Volume 364, Issue 24, pp. 2305 - 2315
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | General aspects | Medical sciences | Humans | Middle Aged | Leukemia, Hairy Cell - genetics | Male | MAP Kinase Kinase Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Lymphoma, B-Cell - genetics | Sequence Analysis, DNA | Leukemia, Hairy Cell - metabolism | Proto-Oncogene Proteins B-raf - genetics | Lymphoma, B-Cell - pathology | Adult | Female | Aged | Mutation | Leukemia, Hairy Cell - pathology | Care and treatment | Genetic aspects | Research | Diagnosis | Gene mutations | Leukemia, Hairy cell | Spleen | Flow cytometry | Hematology | Hairy cells | Leukemia | Extracellular signal-regulated kinase | MAP kinase | Genomes | Kinases | Medical diagnosis | Patients | Lymphoma | Studies | Lymphocytes B | Protein kinase | Genetic analysis | Peripheral blood | Bone marrow | Deoxyribonucleic acid--DNA | Tumors | B-cell lymphoma | Index Medicus | Abridged Index Medicus
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7. Full Text Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1
by Alexander Kohlmann and Vera Grossmann and Hans-Ulrich Klein and Sonja Schindela and Tamara Weiss and Beray Kazak and Frank Dicker and Susanne Schnittger and Martin Dugas and Wolfgang Kern and Claudia Haferlach and Torsten Haferlach
Journal of clinical oncology, ISSN 0732-183X, 08/2010, Volume 28, Issue 24, pp. 3858 - 3865
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Proto-Oncogene Proteins c-cbl - genetics | Predictive Value of Tests | ras Proteins - genetics | Prognosis | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Middle Aged | Kaplan-Meier Estimate | Male | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Adult | Female | Aged | Mutation | Genes, ras | Core Binding Factor Alpha 2 Subunit - genetics | Sequence Analysis, DNA - methods | Index Medicus
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8. Full Text Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia
by Meggendorfer, Manja and Haferlach, Torsten and Alpermann, Tamara and Jeromin, Sabine and Haferlach, Claudia and Kern, Wolfgang and Schnittger, Susanne
Haematologica (Roma), ISSN 0390-6078, 12/2014, Volume 99, Issue 12, pp. e244 - e246
Molecular pattern | aCML | Chronic myelomonocytic leukemia | Chronic neutrophilic leukemia | Life Sciences & Biomedicine | Hematology | Science & Technology | Leukemia, Neutrophilic, Chronic - diagnosis | Leukemia, Myelomonocytic, Chronic - diagnosis | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - diagnosis | Prognosis | Humans | Leukemia, Myelomonocytic, Chronic - genetics | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Female | Male | Biomarkers, Tumor - genetics | Leukemia, Neutrophilic, Chronic - genetics | Mutation - genetics | Index Medicus | Online Only | chronic neutrophilic leukemia | molecular pattern | chronic myelomonocytic leukemia
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9. Full Text Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA
by Susanne Schnittger and Ulrike Bacher and Claudia Haferlach and Wolfgang Kern and Tamara Alpermann and Torsten Haferlach
Haematologica (Roma), ISSN 0390-6078, 12/2011, Volume 96, Issue 12, pp. 1799 - 1807
Additional chromosomal alterations | Acute promyelocytic leukemia | FLT3 mutations | Prognosis | FLT3-ITD/wt ratio | Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Chromosome aberrations | Medical genetics | Translocation, Genetic | Tretinoin - administration & dosage | Humans | Middle Aged | Male | Survival Rate | Antineoplastic Agents - administration & dosage | Chromosomes, Human, Pair 15 - genetics | Chromosomes, Human, Pair 17 - genetics | fms-Like Tyrosine Kinase 3 - genetics | Disease-Free Survival | Oncogene Proteins, Fusion - genetics | Leukemia, Promyelocytic, Acute - mortality | Adult | Female | Aged | Leukemia, Promyelocytic, Acute - genetics | Leukemia, Promyelocytic, Acute - drug therapy | Index Medicus | acute promyelocytic leukemia | FLT3-ITD | wt ratio | additional chromosomal alterations | Original | prognosis
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10. Full Text Deep Molecular Response Is Reached by the Majority of Patients Treated With Imatinib, Predicts Survival, and Is Achieved More Quickly by Optimized High-Dose Imatinib: Results From the Randomized CML-Study IV
by Rüdiger Hehlmann and Martin C. Müller and Michael Lauseker and Benjamin Hanfstein and Alice Fabarius and Annette Schreiber and Ulrike Proetel and Nadine Pletsch and Markus Pfirrmann and Claudia Haferlach and Susanne Schnittger and Hermann Einsele and Jolanta Dengler and Christiane Falge and Lothar Kanz and Andreas Neubauer and Michael Kneba and Frank Stegelmann and Michael Pfreundschuh and Cornelius F. Waller and Karsten Spiekermann and Gabriela M. Baerlocher and Gerhard Ehninger and Dominik Heim and Hermann Heimpel and Christoph Nerl and Stefan W. Krause and Dieter K. Hossfeld and Hans-Jochem Kolb and Joerg Hasford and Susanne Saußele and Andreas Hochhaus
Journal of clinical oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 5, pp. 415 - 423
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Piperazines - administration & dosage | Humans | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Male | Protein Kinase Inhibitors - adverse effects | Molecular Targeted Therapy | Young Adult | Benzamides - administration & dosage | Time Factors | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Aged, 80 and over | Adult | Female | Benzamides - adverse effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - mortality | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Pyrimidines - administration & dosage | Risk Factors | Proportional Hazards Models | Treatment Outcome | Imatinib Mesylate | Piperazines - adverse effects | Remission Induction | Cytarabine - administration & dosage | Disease Progression | Interferon-alpha - administration & dosage | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Fusion Proteins, bcr-abl - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Fusion Proteins, bcr-abl - antagonists & inhibitors | Pyrimidines - adverse effects | Aged | Fusion Proteins, bcr-abl - metabolism | Index Medicus
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11. Full Text Dominant-negative mutations of CEBPA , encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia
by Pabst, Thomas and Radomska, Hanna S and Tenen, Daniel G and Hiddemann, Wolfgang and Schnittger, Susanne and Narravula, Sailaja and Zhang, Pu and Mueller, Beatrice U and Behre, Gerhard
Nature genetics, ISSN 1061-4036, 03/2001, Volume 27, Issue 3, pp. 263 - 270
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Sequence Deletion | DNA, Neoplasm - metabolism | Leukemia, Myeloid, Acute - pathology | Humans | Leukemia, Myeloid, Acute - metabolism | Transcriptional Activation | DNA Primers - genetics | CCAAT-Enhancer-Binding Protein-alpha - chemistry | Cell Differentiation - genetics | CCAAT-Enhancer-Binding Protein-alpha - biosynthesis | Cell Nucleus - metabolism | Genes, Dominant | Base Sequence | CCAAT-Enhancer-Binding Protein-alpha - genetics | Granulocytes - pathology | Heterozygote | Mutation | In Vitro Techniques | Leukemia, Myeloid, Acute - genetics | Neutrophils - pathology | CCAAT/enhancer binding protein-^a | CEBPA gene | Index Medicus
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12. Full Text Recurrent SETBP1 mutations in atypical chronic myeloid leukemia
by Piazza, Rocco and Valletta, Simona and Winkelmann, Nils and Redaelli, Sara and Spinelli, Roberta and Pirola, Alessandra and Antolini, Laura and Mologni, Luca and Donadoni, Carla and Papaemmanuil, Elli and Schnittger, Susanne and Kim, Dong-Wook and Boultwood, Jacqueline and Rossi, Fabio and Gaipa, Giuseppe and De Martini, Greta P and Di Celle, Paola Francia and Jang, Hyun Gyung and Fantin, Valeria and Bignell, Graham R and Magistroni, Vera and Haferlach, Torsten and Pogliani, Enrico Maria and Campbell, Peter J and Chase, Andrew J and Tapper, William J and Cross, Nicholas C.P and Gambacorti-Passerini, Carlo
Nature genetics, ISSN 1061-4036, 01/2013, Volume 45, Issue 1, pp. 18 - 24
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Amino Acid Sequence | Prognosis | Histone Chaperones - genetics | Humans | Histone Chaperones - metabolism | Molecular Sequence Data | Nuclear Proteins - metabolism | Transcription Factors - genetics | Sequence Analysis, DNA | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - mortality | Amino Acid Motifs | Exome | Transcription Factors - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Protein Phosphatase 2 - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Protein Binding | Protein Interaction Domains and Motifs | Mutation | Nuclear Proteins - genetics | Amino Acid Substitution | Gene mutations | Genetic aspects | Chronic myeloid leukemia | Research | Health aspects | Oncogenes | Cancer | Proteins | Databases | Pathogenesis | Genetic testing | Deoxyribonucleic acid--DNA | Index Medicus
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