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Trends in genetics : TIG, ISSN 0168-9525, 6/2015, Volume 31, Issue 6, pp. 290 - 299
Insulin-producing β-cells within the pancreatic islet of Langerhans are responsible for maintaining glucose homeostasis; the loss or malfunction of β-cells... 
long noncoding RNAs | Pancreas | islet | β-cells | epigenetic
Journal Article
Trends in Genetics, ISSN 0168-9525, 06/2015, Volume 31, Issue 6, pp. 290 - 299
Insulin-producing beta cells within the pancreatic islet of Langerhans are responsible for maintaining glucose homeostasis; the loss or malfunction of beta... 
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 08/2012, Volume 23, Issue 6, pp. 655 - 655
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2019, Volume 129, Issue 1, pp. 268 - 280
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2019, Volume 129, Issue 1, p. 268
Notch signaling regulates differentiation of the pancreatic endocrine lineage during embryogenesis, but the role of Notch in mature [beta] cells is unclear. We... 
Cell proliferation | Obesity | Rats as laboratory animals | Cellular signal transduction | Research | Health aspects | Risk factors
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2019, Volume 48, Issue 1, p. 7
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3516 - 3528
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2004, Volume 101, Issue 9, pp. 2924 - 2929
Journal Article
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 2015, Volume 309, Issue 12, pp. G975 - G987
There are two major stem cell populations in the intestinal crypt region that express either Bmi1 or Lgr5; however, it has been shown that other populations in... 
Lgr5 | Bmi1 | Enteroendocrine cells | Nkx2.2 | Stem cells | PROGENITOR CELLS | stem cells | TRANSCRIPTION FACTOR NKX2.2 | PHYSIOLOGY | POPULATIONS | enteroendocrine cells | RENEWAL | ENDOCRINE CELL | MOUSE SMALL INTESTINE | EPITHELIAL-CELLS | STEM-CELL | MICE | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | Intestinal Mucosa - radiation effects | Whole-Body Irradiation | Intestinal Mucosa - metabolism | Cell Proliferation | Receptors, G-Protein-Coupled - metabolism | Polycomb Repressive Complex 1 - metabolism | Homeodomain Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Differentiation | Enteroendocrine Cells - metabolism | Biomarkers - metabolism | Proto-Oncogene Proteins - metabolism | Enteroendocrine Cells - pathology | Mice, Inbred C57BL | Cells, Cultured | Enteroendocrine Cells - radiation effects | Genotype | Mice, Transgenic | Transcription Factors - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Lineage | Phenotype | Animals | Luminescent Proteins - genetics | Intestinal Mucosa - pathology | Luminescent Proteins - metabolism | Physiological aspects | Homeostasis | Physiological research | Research | Rodents | Gastroenterology | Biomarkers | Genetics | Gene expression | Index Medicus | Call for Papers
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2019, Volume 48, Issue 1, pp. 7 - 8
β cell heterogeneity has emerged as an important contributor to islet function, with potential implications for diabetes. Using an optimized smFISH technique... 
HETEROGENEITY | DEVELOPMENTAL BIOLOGY | ISLETS | CELL BIOLOGY
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2013, Volume 9, Issue 2, pp. e1003278 - e1003278
During pancreatic development, transcription factor cascades gradually commit precursor populations to the different endocrine cell fate pathways. Although... 
PROGENITORS | DETERMINANTS | BETA-CELLS | ARX | GENETICS & HEREDITY | NKX2.2 | PAX4 | ALPHA-CELL | DIFFERENTIATION | SPECIFICATION | EXPRESSION | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction |