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中国科学:化学英文版, ISSN 1674-7291, 2017, Volume 60, Issue 2, pp. 201 - 213
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2011, Volume 133, Issue 28, pp. 10784 - 10786
Native chemical ligation (NCL) is widely applicable for building proteins in the laboratory. Since the discovery of this method, many strategies have been... 
RECOGNITION | NATIVE CHEMICAL LIGATION | THIYL RADICALS | CYSTEINE | DESULFURIZATION | GLYCOPEPTIDE SYNTHESIS | PROTEIN-SYNTHESIS | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | INSIGHTS | Proteins - chemistry | Proteins - chemical synthesis | Stereoisomerism | Proline - chemistry | Sulfur - chemistry | Proline | Thiols | Chemical properties | Research | Structure | Protein binding
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2016, Volume 138, Issue 14, pp. 4890 - 4899
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2012, Volume 134, Issue 8, pp. 3912 - 3916
Application of native chemical ligation logic to the case of an N-terminal proline is described. Two approaches were studied. One involved incorporation of a... 
PEPTIDES | SELENOCARBOXYLATES | NATIVE CHEMICAL LIGATION | VALINE | SITES | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | Erythropoietin - chemical synthesis | Erythropoietin - chemistry | Molecular Structure | Proline - analogs & derivatives | Stereoisomerism | Proline - chemistry | Proline | Chemical properties | Structure | Analysis | Peptide bonds
Journal Article
Science China Chemistry, ISSN 1674-7291, 12/2018, Volume 61, Issue 12, pp. 1477 - 1478
Journal Article
Chemical Science, ISSN 2041-6520, 01/2018, Volume 9, Issue 7, pp. 1940 - 1946
Peptidyl thioesters or their surrogates with C-terminal β-branched hydrophobic amino acid residues usually exhibit poor reactivities in ligation reactions.... 
Additives | Activation | Thioesters | Orthogonality | Valine | Desulfurizing
Journal Article
Organic Letters, ISSN 1523-7060, 12/2018, Volume 20, Issue 23, pp. 7670 - 7673
The cypemycin decarboxylase CypD is investigated by using a synthetic oligopeptide, which contains the to-be-cyclized dehydroalanine (Dha) residue. It was... 
OXIDATIVE DECARBOXYLATION | SUBSTRATE-SPECIFICITY | DEHYDROALANINE | PEPTIDES | GENE-CLUSTER | THIOCARBONYL COMPOUNDS | NATURAL-PRODUCTS | BIOSYNTHESIS | CHEMISTRY, ORGANIC | HETEROLOGOUS EXPRESSION | THIOVIRIDAMIDE
Journal Article
Chinese Chemical Letters, ISSN 1001-8417, 07/2018, Volume 29, Issue 7, pp. 1131 - 1134
Journal Article
Journal of Alloys and Compounds, ISSN 0925-8388, 02/2017, Volume 694, pp. 549 - 555
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2008, Volume 130, Issue 9, pp. 2738 - 2739
An enantioselective approach to bicyclo[2.2.2]octenone structures utilizing a copper-mediated asymmetric oxidative dearomatization/[4 + 2] dimerization cascade... 
COMPLEX | TYROSINASE | HYDROXYLATION | REACTIVITY | LIGAND | MODEL | CLEAVAGE | CHEMISTRY, MULTIDISCIPLINARY | 3,10-DIHYDROXYDIELMENTHA-5,11-DIENE-4,9-DIONE | DEAROMATIZATION | SKELETON
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 12/2017, Volume 17, Issue 1, pp. 884 - 13
Background: The primary aim of this study was to evaluate the safety of a novel dendritic cell (DC) vaccine pulsed with survivin and MUC1, silenced with... 
Phase I clinical trial | Modified-DCvaccine | Non-small cell lung cancer (NSCLC) | DENDRITIC CELLS | SURVIVIN | INNATE IMMUNE-RESPONSE | MUC1 EXPRESSION | PROGNOSTIC VALUE | CELL LUNG-CANCER | SOCS1 | ONCOLOGY | IMMUNOTHERAPY | REGULATORY T-CELLS | ANTITUMOR IMMUNITY | Prognosis | Follow-Up Studies | Carcinoma, Large Cell - prevention & control | Dendritic Cells - immunology | Humans | Middle Aged | Vaccination | Lung Neoplasms - pathology | Male | Young Adult | Carcinoma, Large Cell - secondary | Carcinoma, Large Cell - immunology | Adult | Female | Carcinoma, Non-Small-Cell Lung - pathology | Adenocarcinoma - immunology | Cancer Vaccines - administration & dosage | Autoantigens | Survival Rate | Lymphatic Metastasis | Carcinoma, Squamous Cell - prevention & control | Carcinoma, Squamous Cell - immunology | Adenocarcinoma - secondary | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Adenocarcinoma - prevention & control | Lung Neoplasms - prevention & control | Adolescent | Quality of Life | Carcinoma, Squamous Cell - secondary | Aged | Carcinoma, Non-Small-Cell Lung - prevention & control | Complications and side effects | Antigens | Medical research | Cytokines | Dendritic cells | Mucins | Clinical trials | Medicine, Experimental | Product development | Vaccines | Lung cancer, Non-small cell
Journal Article
Cell Reports, ISSN 2211-1247, 04/2019, Volume 27, Issue 5, pp. 1567 - 1578.e5
In vertebrates, hematopoiesis occurring in different niches is orchestrated by intrinsic and extrinsic regulators. Previous studies have revealed numerous... 
hematopoietic stem and progenitor cell | 3D atlas | multi-dimensional RNA-seq | signaling | zebrafish | MIGRATION | TRANSCRIPTOME | VASCULAR NICHE | SELF-RENEWAL | DIFFERENTIATION | AORTIC ENDOTHELIUM | CELL BIOLOGY
Journal Article