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Nature Reviews Cancer, ISSN 1474-175X, 04/2016, Volume 16, Issue 5, pp. 275 - 287
Journal Article
JAMA, ISSN 0098-7484, 11/2017, Volume 318, Issue 17, pp. 1647 - 1648
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2018, Volume 378, Issue 21, pp. 1976 - 1986
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2011, Volume 29, Issue 36, pp. 4828 - 4836
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2010, Volume 28, Issue 19, pp. 3167 - 3175
Journal Article
Science, ISSN 0036-8075, 10/2006, Volume 314, Issue 5796, pp. 126 - 129
Journal Article
Immunity, ISSN 1074-7613, 11/2014, Volume 41, Issue 5, pp. 682 - 684
CTLA-4 is a key immune checkpoint in maintaining self-tolerance, which can be co-opted by cancer to evade immune attack. In , describe clinical manifestations... 
T-CELL FUNCTION | CTLA-4 | IMMUNOLOGY | Animals | Immune System Diseases - genetics | Humans | Germ-Line Mutation | CTLA-4 Antigen - genetics | Female | Male | Immunity - genetics | Haploinsufficiency | Medical research | T cell receptors | Kinases | Immune system
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2003, Volume 349, Issue 5, pp. 427 - 434
In this randomized trial, an antibody against vascular endothelial growth factor, bevacizumab, prolonged the time to progression of disease in patients with... 
MEDICINE, GENERAL & INTERNAL | INHIBITION | PROTEIN | THERAPY | ANGIOGENESIS | PRODUCT | TUMOR-SUPPRESSOR GENE | EMBRYONIC LETHALITY | CARCINOMA | EXPRESSION | HYPOXIA-INDUCIBLE FACTORS | Vascular Endothelial Growth Factor A | Kidney Neoplasms - genetics | Vascular Endothelial Growth Factors | Humans | Ligases - genetics | Middle Aged | Antibodies, Monoclonal - adverse effects | Carcinoma, Renal Cell - genetics | Antibodies, Monoclonal - therapeutic use | Male | Bevacizumab | Endothelial Growth Factors - immunology | Antibodies, Monoclonal, Humanized | Lymphokines - antagonists & inhibitors | Female | Carcinoma, Renal Cell - drug therapy | Genes, Tumor Suppressor | Double-Blind Method | Lymphatic Metastasis | Disease Progression | Endothelial Growth Factors - antagonists & inhibitors | Ubiquitin-Protein Ligases | Adenocarcinoma, Clear Cell - secondary | Neovascularization, Pathologic - drug therapy | Carcinoma, Renal Cell - secondary | Lymphokines - immunology | Kidney Neoplasms - pathology | Von Hippel-Lindau Tumor Suppressor Protein | Kidney Neoplasms - drug therapy | Adenocarcinoma, Clear Cell - genetics | Intercellular Signaling Peptides and Proteins - immunology | Tumor Suppressor Proteins | Adenocarcinoma, Clear Cell - drug therapy | Monoclonal antibodies | Drug therapy | Carcinoma, Renal cell | Proteins | Studies | Angiogenesis | Cytokines | Rodents | Mutation | Vascular endothelial growth factor | Cancer
Journal Article
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 06/2016, Volume 4, Issue 1, p. 37
The Common Rule is a set of ethical principles that provide guidance on the management of human subjects taking part in biomedical and behavioral research in... 
CELL LUNG-CANCER | PEMBROLIZUMAB | MELANOMA | ONCOLOGY | SAFETY | ANTIBODY | IMMUNOLOGY | NIVOLUMAB | IPILIMUMAB | Care and treatment | Research | Health aspects | Immunotherapy | Cancer | Medical research | Regulatory agencies | Participation | Clinical trials | Patients | Cancer therapies | Ethics | Biomarkers | Informed consent | Regulation | Society | Pharmaceutical industry
Journal Article
Cancer Research, ISSN 0008-5472, 07/2015, Volume 75, Issue 14 Supplement, pp. IA19 - IA19
Journal Article
Journal Article
Journal Article