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humans (7) 7
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glycemia (1) 1
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1. Full Text Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
by Olldashi, Fatos and Kerçi, Mihal and Zhurda, Tefik and Ruçi, Klotilda and Banushi, Arben and Traverso, Mario Sardón and Jiménez, Juan and Balbi, Jorge and Dellera, Christian and Svampa, Silvana and Quintana, Gustavo and Piñero, Gustavo and Teves, Jorge and Seppelt, Ian and Mountain, David and Hunter, John and Balogh, Zsolt and Zaman, Maniruz and Druwé, Patrick and Rutsaert, Robert and Mazairac, Guy and Pascal, Fogang and Yvette, Zognou and Chancellin, Djeuchon and Okwen, Patrick and Djokam-Liapoe, Jules and Jangwa, Ernest and Mbuagbaw, Lawrence and Fointama, Ninying and Pascal, Nguemo and Baillie, Frank and Jiang, Ji-Yao and Gao, Guo-Yi and Bao, Yin-Hui and Morales, Carlos and Sierra, Juan and Naranjo, Santiago and Correa, Camilo and Gómez, Carolina and Herrera, Jorge and Caicedo, Liliana and Rojas, Alexei and Pastas, Henry and Miranda, Hugo and Constaín, Alfredo and Perdomo, Mayla and Muñoz, Diego and Duarte, Álvaro and Vásquez, Edwin and Ortiz, Camilo and Ayala, Bernardo and Delgado, Hernán and Benavides, Gloria and Rosero, Lorena and Mejía-Mantilla, Jorge and Varela, Ana and Calle, Maríaisabel and Castillo, José and García, Alberto and Ciro, Juan and Villa, Clara and Panesso, Roberto and Flórez, Luz and Gallego, Argemiro and Puentes-Manosalva, Fabián and Medina, Leonor and Márquez, Kelly and Romero, Adalgiza Reyes and Hernández, Ricardo and Martínez, Julio and Gualteros, Wilson and Urbina, Zulma and Velandia, Julio and Benítez, Federico and Trochez, Adolfo and Villarreal, Andrés and Pabón, Pamela and López, Héctor and Quintero, Laureano and Rubiano, Andrés and Tamayo, Juan and Piñera, Marjoris and Navarro, Zadis and Rondón, Deborah and Bujan, Bárbara and Palacios, Leonel and Martínez, Daymis and Hernández, Yalisa and Fernández, Yaimara and Casola, Eugenio and Delgado, Rodolfo and Herrera, Carlos and Arbolaéz, Migdacelys and Domínguez, Mario and Iraola, Marcos and Rojas, Omar and Enseñat, Alba and Pastrana, Irene and Rodríguez, Daniel and De La Campa, Sergio Álvarez and ... and Crash 2 Trial Collaborators and CRASH-2 trial collaborators
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9734, pp. 23 - 32
Summary Background Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | BRAIN-INJURY | EPIDEMIOLOGY | Antifibrinolytic Agents - therapeutic use | Hemorrhage - therapy | Humans | Wounds and Injuries - complications | Hemorrhage - mortality | Male | Tranexamic Acid - therapeutic use | Hemorrhage - drug therapy | Blood Transfusion | Thrombosis - etiology | Hemorrhage - etiology | Adult | Female | Thrombosis - prevention & control | Prevention | Complications and side effects | Tranexamic acid | Dosage and administration | Research | Blood transfusion | Health aspects | Hemorrhage | Risk factors | Colleges & universities | Clinical trials | Blood pressure | Charitable foundations | Trauma | Injuries | Binding sites | Teaching hospitals
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2. Full Text The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
by Olldashi, Fatos and Kerçi, Mihal and Zhurda, Tefik and Ruçi, Klotilda and Banushi, Arben and Traverso, Mario Sardón and Jiménez, Juan and Balbi, Jorge and Dellera, Christian and Svampa, Silvana and Quintana, Gustavo and Piñero, Gustavo and Teves, Jorge and Seppelt, Ian and Mountain, David and Balogh, Zsolt and Zaman, Maniruz and Druwé, Patrick and Rutsaert, Robert and Mazairac, Guy and Pascal, Fogang and Yvette, Zognou and Chancellin, Djeuchon and Okwen, Patrick and Djokam-Liapoe, Jules and Jangwa, Ernest and Mbuagbaw, Lawrence and Fointama, Ninying and Baillie, Frank and Jiang, Ji-Yao and Gao, Guo-Yi and Bao, Yin-Hui and Morales, Carlos and Sierra, Juan and Naranjo, Santiago and Correa, Camilo and Gómez, Carolina and Herrera, Jorge and Caicedo, Liliana and Rojas, Alexei and Pastas, Henry and Miranda, Hugo and Constaín, Alfredo and Perdomo, Mayla and Muñoz, Diego and Duarte, Álvaro and Vásquez, Edwin and Ortiz, Camilo and Ayala, Bernardo and Delgado, Hernán and Benavides, Gloria and Rosero, Lorena and Mejía-Mantilla, Jorge and Varela, Ana and Calle, Maríaisabel and Castillo, José and García, Alberto and Ciro, Juan and Villa, Clara and Panesso, Roberto and Flórez, Luz and Gallego, Argemiro and Puentes-Manosalva, Fabián and Medina, Leonor and Márquez, Kelly and Romero, Adalgiza Reyes and Hernández, Ricardo and Martínez, Julio and Gualteros, Wilson and Urbina, Zulma and Velandia, Julio and Benítez, Federico and Trochez, Adolfo and Villarreal, Andrés and Pabón, Pamela and López, Héctor and Quintero, Laureano and Rubiano, Andrés and Tamayo, Juan and Piñera, Marjoris and Martínez, Daimi and Martínez, Heriberto and Casola, Eugenio and Domínguez, Mario and Herrera, Carlos and Iraola, Marcos and Rojas, Omar and Pastrana, Irene and Rodríguez, Daniel and De La Campa, Sergio Álvarez and Fortún, Thorvald and Larrea, Martha and Aragón, Lensky and Madrazo, Aida and Svoboda, Petr and Izurieta, Mario and Daccach, Alberto and Altamirano, Mónica and Ortega, Antonio and Cárdenas, Bolívar and ... and CRASH-2 Collaborators and CRASH-2 collaborators
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9771, pp. 1096 - 1101.e2
Summary Background The aim of the CRASH-2 trial was to assess the effects of early administration of tranexamic acid on death, vascular occlusive events, and... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | COAGULOPATHY | Antifibrinolytic Agents - therapeutic use | Hemorrhage - drug therapy | Time Factors | Humans | Wounds and Injuries - complications | Hemorrhage - mortality | Adult | Logistic Models | Tranexamic Acid - therapeutic use | Clinical trials | Data collection | Blood pressure | Statistical analysis | Acids | Charitable foundations
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3. Full Text Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients
by Menon and Harrison and MRC CRASH Trial Collaborators
BMJ, ISSN 0959-8138, 02/2008, Volume 336, Issue 7641, pp. 425 - 429
Objective To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain... 
High income | Health outcomes | Traumatic brain injury | Low income | Database models | Disabilities | Physical trauma | Computerized axial tomography | Calibration | Research | Modeling | MEDICINE, GENERAL & INTERNAL | HEAD-INJURY | MANAGEMENT | COUNTRIES | ADULTS | VARIABLES | PLACEBO-CONTROLLED TRIAL | MRC CRASH | Multivariate Analysis | Brain Injuries - diagnostic imaging | Prognosis | Glasgow Coma Scale | Humans | Accidents, Traffic - statistics & numerical data | Income | Tomography, X-Ray Computed | Brain Injuries - mortality | Cohort Studies | Outcome Assessment (Health Care) - standards
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4. Full Text Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): Randomised placebo-controlled trial
by Olldashi, Fatos and Muzha, Itan and Filipi, Nikolin and Lede, Roberto and Copertari, Pablo and Traverso, Carolina and Copertari, Alejandro and Vergara, Enrique Alfredo and Montenegro, Carolina and De Huidobro, Roberto Ruiz and Surt, Karina and Cialzeta, José and Lazzeri, Silvio and Piñero, Gustavo and Ciccioli, Fabiana and Videtta, Walter and Barboza, María Fernanda and Svampa, Silvana and Sciuto, Victor and Domeniconi, Gustavo and Bustamante, Marcelo and Waschbusch, Maximiliano and Gullo, María Paula and Drago, Daniel Alberto and Linares, Juan Carlos Arjona and Camputaro, Luis and Tróccoli, Gustavo and Galimberti, Hernán and Tallott, Mandy and Eybner, Christian and Buchinger, Walter and Fitzal, Sylvia and Mazairac, Guy and Oleffe, Véronique and Grollinger, Thierry and Delvaux, Philippe and Carlier, Laurent and Braet, Veronique and Jacques, Jean-Marie and De Knoop, Danielle and Nasi, Luiz and Choi, Humberto Kukhuyn and Schmitt, Mara and Gentil, André and Nacul, Flavio and Barrios, Pedro Bedoya and Xinkang, Chen and Hua, Lin Shao and Tian, Huang Han and Xiaodong, Cai and Gualteros, Wilson and Otero, Alvaro Ardila and Arango, Miguel and Ciro, Juan and Jaramillo, Hector and Garcia, Gloria and Gonzalez, Ignacio and Gomez, Carolina and Arias, Arturo and Fonseca, Marco and Mora, Carlos and Cabrera, Edgar Giovanni Luna and Betancurth, José Luis and Muñoz, Porfirio and Quiñónez, Jesus Alberto and Castillo, Maria Esther Gonzalez and Lopez, Orlando and Yepes, Rafael Perez and Cuellar, Diana Leon and Paez, Gerson and Chaves, Hernán Delgado and Ordoñez, Pablo Emilio and Plata, Ricardo and Pineda, Martha and Pulido, Libardo Enrique and Jaramillo, John Sergio Velez and Rebolledo, Carlos and Palma, Oscar and Soler, Caridad and Pastrana, Irene and Falero, Raul and Perera, Mario Domínguez and García, Agustín Arocha and Oliva, Raydel and Delgado, Hubiel López and Carnero, Aida Madrazo and López, Boris Leyva and Gallardo, Angel Lacerda and Morales, Amarilys Ortega and Lezcano, Humberto and Ferrer, Marcos Iraola and Bess, Irene Zamalea and Canino, Gladys Rivas and Ruiz, Ernesto Miguel Piferrer and Cruz, Orlando Garcia and Svoboda, Petr and Kantorová, Ilona and Ochmann, Jiří and Scheer, Peter and Kozumplík, Ladislav and ... and CRASH Trial Collaborators and CRASH trial collaborators
The Lancet, ISSN 0140-6736, 10/2004, Volume 364, Issue 9442, pp. 1321 - 1328
Background Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs... 
MEDICINE, GENERAL & INTERNAL | SPINAL-CORD-INJURY | METHYLPREDNISOLONE | BRAIN-INJURY | INTENSIVE-CARE | CARE MANAGEMENT | Glucocorticoids - administration & dosage | Double-Blind Method | Humans | Middle Aged | Risk Factors | Craniocerebral Trauma - mortality | Male | Survival Rate | Tomography, X-Ray Computed | Craniocerebral Trauma - diagnostic imaging | Craniocerebral Trauma - drug therapy | Glasgow Coma Scale | Adolescent | Adult | Female | Infusions, Intravenous | Methylprednisolone - administration & dosage
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5. Full Text Hyperglycemia and Short-term Outcome in Patients with Spontaneous Intracerebral Hemorrhage
by Godoy, Daniel A and Piñero, Gustavo R and Svampa, Silvana and Papa, Francesca and Di Napoli, Mario
Neurocritical Care, ISSN 1541-6933, 10/2008, Volume 9, Issue 2, pp. 217 - 229
Hyperglycemia has a detrimental effect in several acute neurological critical illnesses. No consensus exists on the optimal management of hyperglycemia in... 
Neurology | Prognosis | Medicine & Public Health | Outcome | Diagnostic accuracy | Risk factor | Internal Medicine | Insulin | Intracerebral hemorrhage | Glycemia | diagnostic accuracy | QUALITY-OF-CARE | MANAGEMENT | insulin | GLUCOSE LEVEL | BLOOD-GLUCOSE | GUIDELINES | prognosis | risk factor | CLINICAL NEUROLOGY | intracerebral hemorrhage | DIABETES-MELLITUS | glycemia | ADMISSION HYPERGLYCEMIA | ISCHEMIC-STROKE | outcome | ASSOCIATION STROKE COUNCIL | CRITICAL CARE MEDICINE | Critical Care - statistics & numerical data | Hypoglycemic Agents - therapeutic use | Multivariate Analysis | Predictive Value of Tests | Acute Disease | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Cerebral Hemorrhage - mortality | Blood Glucose | Male | Tomography, X-Ray Computed | Cerebral Hemorrhage - diagnostic imaging | Hyperglycemia - drug therapy | Pilot Projects | Female | Aged | Hyperglycemia - mortality | Insulin - therapeutic use | Hyperglycemia | Care and treatment | Blood sugar | Patient outcomes | Risk factors
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6. Full Text Latin American Consensus on the use of transcranial Doppler in the diagnosis of brain death
by Pardo, Alfredo Vivas and Cacciatori, Armando and Dorfman, Bernardo and Heredia, Carlos and Llano, Miguel and Puppo, Corina and Godoy, Daniel and Gomes Rodrigues, Daniela Laranja and Morocho, Diego and Solano, Edgardo and Pérez, Elsa and Fariña, Gerardo and Huelmo, Gimena and Previgliano, Ignacio and Moraes, Leandro and Mori, Lilián Benito and Magalhaes, Marcelo Duarte and Chumbe, María Mercedes and Domínguez Perera, Mario A and Hernández Ortiz, Olga H and Pinillos, Oscar and Schoon, Pablo and Romero, Ricardo and Da Re Gutiérrez, Sabrina and Svampa, Silvana and Carino, Silvia and Consensus Group on Transcranial Doppler in Diagnosis of Brain Death and Consensus Group on Transcranial Doppler in the Diagnosis of Brain Death
Revista Brasileira de Terapia Intensiva, ISSN 0103-507X, 07/2014, Volume 26, Issue 3, pp. 240 - 252
Transcranial Doppler evaluates cerebral hemodynamics in patients with brain injury and is a useful technical tool in diagnosing cerebral circulatory arrest,... 
Transcranial | Brain death/diagnosis | Brain death/ultrasonography | Consensus | Doppler | Ultrasonography | Ultrasonography, Doppler, Transcranial - methods | Humans | Brain Injuries - physiopathology | Hemodynamics - physiology | Brain Death - diagnosis | Brain Injuries - diagnosis | Latin America | Special | Doppler, transcranial | diagnosis | ultrasonography | Brain death
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7. Full Text Early Hyperglycemia and Intravenous Insulin—The Rationale and Management of Hyperglycemia for Spontaneous Intracerebral Hemorrhage Patients: Is Time for Change?
by Godoy, Daniel A and Godoy, Daniel A and Piñero, Gustavo R and Piñero, Gustavo R and Svampa, Silvana and Svampa, Silvana and Papa, Francesca and Papa, Francesca and Di Napoli, Mario and Di Napoli, Mario
Neurocritical Care, ISSN 1541-6933, 2/2009, Volume 10, Issue 1, pp. 150 - 153
Medicine & Public Health | Neurology | Internal Medicine | THERAPY | GLUCOSE CONTROL | INTENSIVE INSULIN | RESISTANCE | ISCHEMIC-STROKE | CLINICAL NEUROLOGY | CRITICAL CARE MEDICINE | Hypoglycemic Agents - therapeutic use | Time Factors | Humans | Risk Factors | Treatment Outcome | Hyperglycemia - etiology | Infusions, Intravenous | Cerebral Hemorrhage - complications | Hyperglycemia - drug therapy | Insulin - therapeutic use | Hyperglycemia
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8. Full Text Re‐Envisioning the Sublime: L.E.L.'s Valley of Linmouth
by Svampa, Maria Paola
Literature Compass, ISSN 1741-4113, 05/2008, Volume 5, Issue 3, pp. 554 - 564
This essay won the 2007 Literature Compass Graduate Essay Prize, Romanticism Section. The English romantic poetess Letitia Elizabeth Landon (1802–38), better... 
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