American Journal of Gastroenterology, ISSN 0002-9270, 02/2015, Volume 110, Issue 2, pp. 223 - 262
This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the...
COST-EFFECTIVENESS ANALYSIS | DOUBLE-BALLOON ENTEROSCOPY | GENOTYPE-PHENOTYPE CORRELATIONS | CADHERIN GERMLINE MUTATIONS | NONPOLYPOSIS COLORECTAL-CANCER | MUIR-TORRE-SYNDROME | PEUTZ-JEGHERS-SYNDROME | LYNCH SYNDROME CARRIERS | FAMILIAL ADENOMATOUS POLYPOSIS | GASTROENTEROLOGY & HEPATOLOGY | DIFFUSE GASTRIC-CANCER | Gastrointestinal Neoplasms - genetics | Humans | Peutz-Jeghers Syndrome - therapy | Intestinal Polyposis - diagnosis | Colorectal Neoplasms, Hereditary Nonpolyposis - therapy | Intestinal Polyposis - congenital | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Neoplastic Syndromes, Hereditary - genetics | Adenomatous Polyposis Coli - therapy | Adenomatous Polyposis Coli - genetics | Hamartoma Syndrome, Multiple - genetics | Intestinal Polyposis - therapy | Genetic Testing - standards | Intestinal Polyposis - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Peutz-Jeghers Syndrome - genetics | Hamartoma Syndrome, Multiple - diagnosis | Hamartoma Syndrome, Multiple - therapy | Neoplastic Syndromes, Hereditary - therapy | Peutz-Jeghers Syndrome - diagnosis | Disease Management | Adenomatous Polyposis Coli - diagnosis
COST-EFFECTIVENESS ANALYSIS | DOUBLE-BALLOON ENTEROSCOPY | GENOTYPE-PHENOTYPE CORRELATIONS | CADHERIN GERMLINE MUTATIONS | NONPOLYPOSIS COLORECTAL-CANCER | MUIR-TORRE-SYNDROME | PEUTZ-JEGHERS-SYNDROME | LYNCH SYNDROME CARRIERS | FAMILIAL ADENOMATOUS POLYPOSIS | GASTROENTEROLOGY & HEPATOLOGY | DIFFUSE GASTRIC-CANCER | Gastrointestinal Neoplasms - genetics | Humans | Peutz-Jeghers Syndrome - therapy | Intestinal Polyposis - diagnosis | Colorectal Neoplasms, Hereditary Nonpolyposis - therapy | Intestinal Polyposis - congenital | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Neoplastic Syndromes, Hereditary - genetics | Adenomatous Polyposis Coli - therapy | Adenomatous Polyposis Coli - genetics | Hamartoma Syndrome, Multiple - genetics | Intestinal Polyposis - therapy | Genetic Testing - standards | Intestinal Polyposis - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Peutz-Jeghers Syndrome - genetics | Hamartoma Syndrome, Multiple - diagnosis | Hamartoma Syndrome, Multiple - therapy | Neoplastic Syndromes, Hereditary - therapy | Peutz-Jeghers Syndrome - diagnosis | Disease Management | Adenomatous Polyposis Coli - diagnosis
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 03/2015, Volume 60, Issue 3, pp. 722 - 733
The incidence and mortality rates of colorectal cancer (CRC) have been decreasing in adults over 50 years of age, however, these rates have been increasing in...
Colorectal cancer screening | Young adults | Review | Colorectal cancer | ADJUVANT CHEMOTHERAPY | SOCIETY-TASK-FORCE | FERTILITY PRESERVATION | MICROSATELLITE INSTABILITY | RISK | STAGE-II | COLON-CANCER | RECOMMENDATIONS | MYH MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | Colorectal Neoplasms - epidemiology | Prognosis | Humans | Carcinoma - diagnosis | Carcinoma - etiology | Colorectal Neoplasms - diagnosis | Incidence | Young Adult | Colorectal Neoplasms - etiology | Colorectal Neoplasms - therapy | Mass Screening | Carcinoma - epidemiology | Adult | Carcinoma - therapy | Population Surveillance | Practice Guidelines as Topic | Medical colleges | Mortality | Youth | Health care industry | Teenagers | Diagnosis | Cancer
Colorectal cancer screening | Young adults | Review | Colorectal cancer | ADJUVANT CHEMOTHERAPY | SOCIETY-TASK-FORCE | FERTILITY PRESERVATION | MICROSATELLITE INSTABILITY | RISK | STAGE-II | COLON-CANCER | RECOMMENDATIONS | MYH MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | Colorectal Neoplasms - epidemiology | Prognosis | Humans | Carcinoma - diagnosis | Carcinoma - etiology | Colorectal Neoplasms - diagnosis | Incidence | Young Adult | Colorectal Neoplasms - etiology | Colorectal Neoplasms - therapy | Mass Screening | Carcinoma - epidemiology | Adult | Carcinoma - therapy | Population Surveillance | Practice Guidelines as Topic | Medical colleges | Mortality | Youth | Health care industry | Teenagers | Diagnosis | Cancer
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2017, Volume 35, Issue 22, pp. 2588 - 2589
Journal Article
Gastroenterology, ISSN 0016-5085, 2017
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 2014, Volume 109, Issue 8, pp. 1159 - 1179
The Multi-Society Task Force, in collaboration with invited experts, developed guidelines to assist health care providers with the appropriate provision of...
Diagnosis, Differential | Genetic Predisposition to Disease | Genetic Testing | United States | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Evidence-Based Medicine | Consensus | Advisory Committees | Colorectal Neoplasms, Hereditary Nonpolyposis - therapy | Algorithms | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Pedigree
Diagnosis, Differential | Genetic Predisposition to Disease | Genetic Testing | United States | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Evidence-Based Medicine | Consensus | Advisory Committees | Colorectal Neoplasms, Hereditary Nonpolyposis - therapy | Algorithms | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Pedigree
Journal Article
Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 4, pp. 1076 - 1080.e2
Gastroenterology and Hepatology | HIGH-RISK INDIVIDUALS | PAPILLARY MUCINOUS TUMORS | STRONG FAMILY-HISTORY | BRCA2 MUTATIONS | DUCTAL ADENOCARCINOMAS | GERMLINE P16 MUTATIONS | LINKAGE ANALYSIS | CLINICAL-FEATURES | PRONE FAMILIES | INTRAEPITHELIAL NEOPLASIA | GASTROENTEROLOGY & HEPATOLOGY | Dysplastic Nevus Syndrome - genetics | Pancreatic Neoplasms - epidemiology | Early Detection of Cancer | Pancreatic Neoplasms - diagnosis | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Pancreatic Neoplasms - genetics | Pancreatitis, Chronic - genetics | Peutz-Jeghers Syndrome - genetics | Pancreatic cancer | Genetic aspects
Journal Article
JAMA: The Journal of the American Medical Association, ISSN 0098-7484, 10/2009, Volume 302, Issue 16, pp. 1790 - 1795
CONTEXT Lynch syndrome is an inherited cause of colorectal cancer caused by mutations of DNA mismatch repair (MMR) genes. A number of extracolonic tumors have...
INDIVIDUALS | MEDICINE, GENERAL & INTERNAL | GENE | NONPOLYPOSIS COLORECTAL-CANCER | MEDULLARY CARCINOMA | DNA-MISMATCH-REPAIR | PATIENT | MSH2 MUTATION CARRIERS | ENDOMETRIAL CANCER | HISTORY | ACCURACY | MutL Protein Homolog 1 | Pancreatic Neoplasms - epidemiology | Humans | Middle Aged | Male | Risk | DNA Mismatch Repair - genetics | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Germ-Line Mutation | Adult | Female | Registries | Nuclear Proteins - genetics | SEER Program | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Proportional Hazards Models | Genotype | Pancreatic Neoplasms - genetics | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | Phenotype | Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology | Pedigree | Adaptor Proteins, Signal Transducing - genetics | Aged | Causes of | Research | Gene mutations | Pancreatic cancer | DNA mismatch repair | Risk factors | Families & family life | Genetic disorders | Genes
INDIVIDUALS | MEDICINE, GENERAL & INTERNAL | GENE | NONPOLYPOSIS COLORECTAL-CANCER | MEDULLARY CARCINOMA | DNA-MISMATCH-REPAIR | PATIENT | MSH2 MUTATION CARRIERS | ENDOMETRIAL CANCER | HISTORY | ACCURACY | MutL Protein Homolog 1 | Pancreatic Neoplasms - epidemiology | Humans | Middle Aged | Male | Risk | DNA Mismatch Repair - genetics | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Germ-Line Mutation | Adult | Female | Registries | Nuclear Proteins - genetics | SEER Program | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Proportional Hazards Models | Genotype | Pancreatic Neoplasms - genetics | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | Phenotype | Colorectal Neoplasms, Hereditary Nonpolyposis - epidemiology | Pedigree | Adaptor Proteins, Signal Transducing - genetics | Aged | Causes of | Research | Gene mutations | Pancreatic cancer | DNA mismatch repair | Risk factors | Families & family life | Genetic disorders | Genes
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 1, pp. 49 - 55
Summary Background Lynch syndrome is caused by germline mutations in MSH2, MLH1, MSH6 , and PMS2 mismatch-repair genes and leads to a high risk of colorectal...
Hematology, Oncology and Palliative Medicine | STEM-CELLS | METHYLATION | HYPERMETHYLATION | MANAGEMENT | MSH2 | ONCOLOGY | REPAIR GENE HMSH2 | MUTATION CARRIERS | FAMILIES | SURVEILLANCE | TACSTD1 | Antigens, Neoplasm - genetics | Promoter Regions, Genetic | Sequence Deletion | Cell Adhesion Molecules - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Endometrial Neoplasms - etiology | Male | Risk | MutS Homolog 2 Protein - genetics | Epithelial Cell Adhesion Molecule | Colorectal Neoplasms - etiology | Endometrial Neoplasms - genetics | Gene Deletion | Adolescent | Adult | Female | Aged | Cohort Studies | Prevention | Molecular genetics | Endometrial cancer | Gene mutations | Oncology, Experimental | Research | Universities and colleges | Biometry | Cancer
Hematology, Oncology and Palliative Medicine | STEM-CELLS | METHYLATION | HYPERMETHYLATION | MANAGEMENT | MSH2 | ONCOLOGY | REPAIR GENE HMSH2 | MUTATION CARRIERS | FAMILIES | SURVEILLANCE | TACSTD1 | Antigens, Neoplasm - genetics | Promoter Regions, Genetic | Sequence Deletion | Cell Adhesion Molecules - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Endometrial Neoplasms - etiology | Male | Risk | MutS Homolog 2 Protein - genetics | Epithelial Cell Adhesion Molecule | Colorectal Neoplasms - etiology | Endometrial Neoplasms - genetics | Gene Deletion | Adolescent | Adult | Female | Aged | Cohort Studies | Prevention | Molecular genetics | Endometrial cancer | Gene mutations | Oncology, Experimental | Research | Universities and colleges | Biometry | Cancer
Journal Article
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 06/2018, Volume 319, Issue 23, pp. 2383 - 2385
The article discusses the findings of a study to evaluate whether inherited germline mutations in cancer predisposition genes are associated with an increased...
MEDICINE, GENERAL & INTERNAL | RISK | MANAGEMENT | CANCER | Adenocarcinoma | Pancreatic Neoplasms - genetics | Genetic Testing | Humans | Carcinoma, Pancreatic Ductal - genetics | Usage | Genetic aspects | Diagnosis | Pancreatic cancer | Risk factors | Genetic screening | Disease prevention | Medical treatment | Genetic testing | Pancreas | Medical diagnosis | Guidelines
MEDICINE, GENERAL & INTERNAL | RISK | MANAGEMENT | CANCER | Adenocarcinoma | Pancreatic Neoplasms - genetics | Genetic Testing | Humans | Carcinoma, Pancreatic Ductal - genetics | Usage | Genetic aspects | Diagnosis | Pancreatic cancer | Risk factors | Genetic screening | Disease prevention | Medical treatment | Genetic testing | Pancreas | Medical diagnosis | Guidelines
Journal Article
Gut, ISSN 0017-5749, 07/2013, Volume 62, Issue 7, pp. 1024 - 1033
Objective Pancreatic cysts are commonly detected in patients undergoing pancreatic imaging. Better approaches are needed to characterise these lesions. In this...
PAPILLARY MUCINOUS NEOPLASMS | HIGH-RISK INDIVIDUALS | K-RAS MUTATIONS | METHYLATION | EARLY-DIAGNOSIS | TELOMERASE ACTIVITY | SAMPLES | PREVALENCE | FAMILY-HISTORY | GASTROENTEROLOGY & HEPATOLOGY | CANCER | Early Detection of Cancer - methods | Pancreatic Neoplasms - diagnosis | Humans | Middle Aged | Male | Secretin | Case-Control Studies | Carcinoma, Pancreatic Ductal - genetics | GTP-Binding Protein alpha Subunits, Gs - genetics | Chromogranins | Neoplasm Proteins - secretion | Pancreatic Cyst - pathology | GTP-Binding Protein alpha Subunits, Gs - secretion | Duodenum - metabolism | Aged, 80 and over | Carcinoma, Pancreatic Ductal - diagnosis | Pancreatic Juice - metabolism | Female | Neoplasm Proteins - genetics | Genetic Predisposition to Disease | Pancreatic Neoplasms - pathology | Pancreatic Cyst - diagnosis | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Pancreatic Cyst - genetics | Aged | Biomarkers, Tumor - genetics | DNA, Neoplasm - genetics | Mutation | Early Diagnosis | Genetic aspects | Diagnosis | Research | Gene mutations | Pancreatic cancer | Studies | Hogs | Ultrasonic imaging | Surveillance | Cysts | Rodents | Family medical history | Endoscopy | Deoxyribonucleic acid--DNA | Tumors | GNAS | pancreatic juice | intraductal papillary mucinous neoplasm | pancreatic cyst
PAPILLARY MUCINOUS NEOPLASMS | HIGH-RISK INDIVIDUALS | K-RAS MUTATIONS | METHYLATION | EARLY-DIAGNOSIS | TELOMERASE ACTIVITY | SAMPLES | PREVALENCE | FAMILY-HISTORY | GASTROENTEROLOGY & HEPATOLOGY | CANCER | Early Detection of Cancer - methods | Pancreatic Neoplasms - diagnosis | Humans | Middle Aged | Male | Secretin | Case-Control Studies | Carcinoma, Pancreatic Ductal - genetics | GTP-Binding Protein alpha Subunits, Gs - genetics | Chromogranins | Neoplasm Proteins - secretion | Pancreatic Cyst - pathology | GTP-Binding Protein alpha Subunits, Gs - secretion | Duodenum - metabolism | Aged, 80 and over | Carcinoma, Pancreatic Ductal - diagnosis | Pancreatic Juice - metabolism | Female | Neoplasm Proteins - genetics | Genetic Predisposition to Disease | Pancreatic Neoplasms - pathology | Pancreatic Cyst - diagnosis | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Pancreatic Cyst - genetics | Aged | Biomarkers, Tumor - genetics | DNA, Neoplasm - genetics | Mutation | Early Diagnosis | Genetic aspects | Diagnosis | Research | Gene mutations | Pancreatic cancer | Studies | Hogs | Ultrasonic imaging | Surveillance | Cysts | Rodents | Family medical history | Endoscopy | Deoxyribonucleic acid--DNA | Tumors | GNAS | pancreatic juice | intraductal papillary mucinous neoplasm | pancreatic cyst
Journal Article
JAMA, ISSN 0098-7484, 08/2012, Volume 308, Issue 5, pp. 485 - 492
CONTEXT Patients with multiple colorectal adenomas may carry germline mutations in the APC or MUTYH genes. OBJECTIVES To determine the prevalence of pathogenic...
CANCER PATIENTS | MEDICINE, GENERAL & INTERNAL | MYH GENE-MUTATIONS | GERM-LINE MUTATIONS | FAP | FAMILIES | GUIDELINES | CHROMOSOME-5Q21 | IDENTIFICATION | EXPRESSION | POLYPOSIS PATIENTS | Adenomatous Polyposis Coli Protein - genetics | Cross-Sectional Studies | Adenoma - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | DNA Glycosylases - genetics | Male | Adenomatous Polyposis Coli - pathology | Sequence Analysis, DNA | Phenotype | DNA Mutational Analysis | Adenoma - pathology | Adult | Female | Mutation | Adenomatous Polyposis Coli - genetics | Colorectal Neoplasms - pathology | Care and treatment | Usage | Gene mutations | Colorectal cancer | Genetic aspects | Diagnosis | Research | Nucleotide sequencing | DNA sequencing | Surgical outcomes | Genetic testing | Tumors
CANCER PATIENTS | MEDICINE, GENERAL & INTERNAL | MYH GENE-MUTATIONS | GERM-LINE MUTATIONS | FAP | FAMILIES | GUIDELINES | CHROMOSOME-5Q21 | IDENTIFICATION | EXPRESSION | POLYPOSIS PATIENTS | Adenomatous Polyposis Coli Protein - genetics | Cross-Sectional Studies | Adenoma - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | DNA Glycosylases - genetics | Male | Adenomatous Polyposis Coli - pathology | Sequence Analysis, DNA | Phenotype | DNA Mutational Analysis | Adenoma - pathology | Adult | Female | Mutation | Adenomatous Polyposis Coli - genetics | Colorectal Neoplasms - pathology | Care and treatment | Usage | Gene mutations | Colorectal cancer | Genetic aspects | Diagnosis | Research | Nucleotide sequencing | DNA sequencing | Surgical outcomes | Genetic testing | Tumors
Journal Article
JAMA, ISSN 0098-7484, 08/2008, Volume 300, Issue 8, pp. 907 - 914
CONTEXT Patients with diverticular disease are frequently advised to avoid eating nuts, corn, popcorn, and seeds to reduce the risk of complications. However,...
COLORECTAL-CANCER RISK | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MANAGEMENT | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PROSTATE-CANCER | MEN | MAGNESIUM INTAKE | NATURAL-HISTORY | BLEEDING COLONIC DIVERTICULOSIS | PROSPECTIVE COHORT | Nuts | Prospective Studies | Zea mays | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Incidence | Diet | Health Surveys | Gastrointestinal Hemorrhage - etiology | Adult | Aged | Diverticulitis, Colonic - epidemiology | Diverticulitis, Colonic - complications | Colorectal diseases | Causes of | Corn | Health aspects | Gastrointestinal diseases | Disease | Digestive system | Hemorrhage | Men | Questionnaires | Food
COLORECTAL-CANCER RISK | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MANAGEMENT | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PROSTATE-CANCER | MEN | MAGNESIUM INTAKE | NATURAL-HISTORY | BLEEDING COLONIC DIVERTICULOSIS | PROSPECTIVE COHORT | Nuts | Prospective Studies | Zea mays | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Incidence | Diet | Health Surveys | Gastrointestinal Hemorrhage - etiology | Adult | Aged | Diverticulitis, Colonic - epidemiology | Diverticulitis, Colonic - complications | Colorectal diseases | Causes of | Corn | Health aspects | Gastrointestinal diseases | Disease | Digestive system | Hemorrhage | Men | Questionnaires | Food
Journal Article
Journal of Clinical Epidemiology, ISSN 0895-4356, 06/2018, Volume 98, pp. 133 - 143
To evaluate limitations of common statistical modeling approaches in deriving clinical prediction models and explore alternative strategies. A previously...
Validation | Events per variable | Regression analysis | Simulation | Sample size | Prediction model | RISK PREDICTION | PROGNOSTIC MODELS | LOGISTIC-REGRESSION ANALYSIS | EXTERNAL VALIDATION | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEALTH CARE SCIENCES & SERVICES | ACUTE MYOCARDIAL-INFARCTION | FRAMEWORK | MUTATIONS | SELECTION | Methods | Colorectal cancer | Statistical analysis | Computer simulation | Endometrial cancer | Decision making | Bias | Genes | Colorectal carcinoma | Performance prediction | Calibration | DNA repair | Datasets | Studies | Surveillance | Prediction models | Mismatch repair | Modelling | Mathematical models | Mutation | Statistical modelling | Age | Deoxyribonucleic acid--DNA
Validation | Events per variable | Regression analysis | Simulation | Sample size | Prediction model | RISK PREDICTION | PROGNOSTIC MODELS | LOGISTIC-REGRESSION ANALYSIS | EXTERNAL VALIDATION | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEALTH CARE SCIENCES & SERVICES | ACUTE MYOCARDIAL-INFARCTION | FRAMEWORK | MUTATIONS | SELECTION | Methods | Colorectal cancer | Statistical analysis | Computer simulation | Endometrial cancer | Decision making | Bias | Genes | Colorectal carcinoma | Performance prediction | Calibration | DNA repair | Datasets | Studies | Surveillance | Prediction models | Mismatch repair | Modelling | Mathematical models | Mutation | Statistical modelling | Age | Deoxyribonucleic acid--DNA
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 14, pp. 1713 - 1718
Purpose Prostate cancer has been described as a component tumor of Lynch syndrome (LS), with tumors obtained from mutation carriers demonstrating the DNA...
EXTRACOLONIC CANCERS | GENE | MSH2 | ONCOLOGY | NONPOLYPOSIS COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | FAMILIES | DNA-MISMATCH-REPAIR | GERMLINE MUTATIONS | BRCA1 | CARRIERS | United States - epidemiology | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Middle Aged | Male | Penetrance | Risk | DNA Mismatch Repair - genetics | Incidence | Prostatic Neoplasms - epidemiology | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Heterozygote | Aged | Odds Ratio | Original Reports | Guc43
EXTRACOLONIC CANCERS | GENE | MSH2 | ONCOLOGY | NONPOLYPOSIS COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | FAMILIES | DNA-MISMATCH-REPAIR | GERMLINE MUTATIONS | BRCA1 | CARRIERS | United States - epidemiology | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Middle Aged | Male | Penetrance | Risk | DNA Mismatch Repair - genetics | Incidence | Prostatic Neoplasms - epidemiology | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Heterozygote | Aged | Odds Ratio | Original Reports | Guc43
Journal Article
Familial Cancer, ISSN 1389-9600, 10/2018, Volume 17, Issue 4, pp. 567 - 567
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s10689-018-0074-6
ONCOLOGY | GENETICS & HEREDITY | Heterozygote | Mutation | Colorectal Neoplasms, Hereditary Nonpolyposis | Mismatch Repair Endonuclease PMS2 - genetics | Humans | Liver
ONCOLOGY | GENETICS & HEREDITY | Heterozygote | Mutation | Colorectal Neoplasms, Hereditary Nonpolyposis | Mismatch Repair Endonuclease PMS2 - genetics | Humans | Liver
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2015, Volume 33, Issue 31, pp. 3660 - 3667
The American Society of Clinical Oncology (ASCO) has long affirmed that the recognition and management of individuals with an inherited susceptibility to...
MORTALITY | INCIDENTAL FINDINGS | PANEL | ONCOLOGY | RECOMMENDATIONS | COLORECTAL-CANCER | RISK | Genetic Predisposition to Disease | Risk Assessment | United States | Genetic Testing - legislation & jurisprudence | Genomics | Humans | Medical Oncology - education | Medical Oncology - organization & administration | Quality Assurance, Health Care | Medical Oncology - legislation & jurisprudence | Societies, Medical | Neoplasms - genetics | Health Services Accessibility | Germ-Line Mutation | Genome, Human | Patient Protection and Affordable Care Act
MORTALITY | INCIDENTAL FINDINGS | PANEL | ONCOLOGY | RECOMMENDATIONS | COLORECTAL-CANCER | RISK | Genetic Predisposition to Disease | Risk Assessment | United States | Genetic Testing - legislation & jurisprudence | Genomics | Humans | Medical Oncology - education | Medical Oncology - organization & administration | Quality Assurance, Health Care | Medical Oncology - legislation & jurisprudence | Societies, Medical | Neoplasms - genetics | Health Services Accessibility | Germ-Line Mutation | Genome, Human | Patient Protection and Affordable Care Act
Journal Article
Psycho‐Oncology, ISSN 1057-9249, 07/2018, Volume 27, Issue 7, pp. 1711 - 1718
Objective Describe relationships between self‐reported personal demographics or familial characteristics and psychosocial outcomes (Patient Reported Outcome...
psychosocial | cancer | pancreatic cancer risk | patient reported outcomes | oncology | DISTRESS | SOCIAL SCIENCES, BIOMEDICAL | RISK | WORRY | PSYCHOLOGY | WOMEN | PSYCHOLOGY, MULTIDISCIPLINARY | HEREDITARY BREAST-CANCER | EXPERIENCE | BURDEN | Genetic Predisposition to Disease - psychology | Cross-Sectional Studies | Humans | Middle Aged | Anxiety - psychology | Adult | Female | Male | Pancreatic Neoplasms - psychology | Risk | Aged | Stress, Psychological - psychology | Psychological aspects | Genetic aspects | Pancreatic cancer | Domestic relations | Family characteristics | Measurement | Caregivers | Psychological distress | Perceptions | Risk perception | Caregiving | Health risk assessment | Psychosocial factors | Worry
psychosocial | cancer | pancreatic cancer risk | patient reported outcomes | oncology | DISTRESS | SOCIAL SCIENCES, BIOMEDICAL | RISK | WORRY | PSYCHOLOGY | WOMEN | PSYCHOLOGY, MULTIDISCIPLINARY | HEREDITARY BREAST-CANCER | EXPERIENCE | BURDEN | Genetic Predisposition to Disease - psychology | Cross-Sectional Studies | Humans | Middle Aged | Anxiety - psychology | Adult | Female | Male | Pancreatic Neoplasms - psychology | Risk | Aged | Stress, Psychological - psychology | Psychological aspects | Genetic aspects | Pancreatic cancer | Domestic relations | Family characteristics | Measurement | Caregivers | Psychological distress | Perceptions | Risk perception | Caregiving | Health risk assessment | Psychosocial factors | Worry
Journal Article