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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 10, pp. 4045 - 4050
Glaucoma, a major cause of blindness worldwide, is a neurodegenerative optic neuropathy in which vision loss is caused by loss of retinal ganglion cells... 
Glaucoma | Axons | Optic nerve | Eyes | Cell death | Neurons | Small interfering RNA | Mice | Physical trauma | Ganglia | Neuroprotection | Drug discovery | MAP3K12 | ELECTROPORATION | INHIBITOR SELECTIVITY | MULTIDISCIPLINARY SCIENCES | AXONAL REGENERATION | INJURY | DEGENERATION | drug discovery | PATHWAY | neuroprotection | IN-VIVO | NEURONS | MOUSE RETINA | GLAUCOMA | Glaucoma - etiology | Up-Regulation | Rats, Wistar | Humans | Cell Survival - genetics | Male | Retinal Ganglion Cells - pathology | Optic Nerve Diseases - pathology | Cell Death - genetics | RNA Interference | Optic Nerve Injuries - pathology | MAP Kinase Kinase Kinases - antagonists & inhibitors | Cell Survival - physiology | Disease Models, Animal | Optic Nerve Injuries - drug therapy | Cell Survival - drug effects | Retinal Ganglion Cells - enzymology | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Down-Regulation | Cells, Cultured | Rats | Glaucoma - drug therapy | Piperazines - pharmacology | Optic Nerve Injuries - enzymology | Animals | Cell Death - physiology | MAP Kinase Kinase Kinases - physiology | Protein Kinase Inhibitors - pharmacology | Optic Nerve Diseases - etiology | Retinal Ganglion Cells - drug effects | Genomics | Physiological aspects | Retina | Genetic aspects | Research | Health aspects | Genetic screening | Methods | Mitogen-activated protein kinases | Signal transduction | Rodents | Kinases | Cells | Apoptosis | Index Medicus | Biological Sciences
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2011, Volume 31, Issue 17, pp. 6468 - 6480
Studies using cultured neurons have established the critical role of microtubule regulators in neuronal polarization. The c-Jun N-terminal kinase (JNK) pathway... 
MIGRATION | CORTICAL-NEURONS | PHOSPHORYLATION | NEURITE INITIATION | REGENERATION | GROWTH | BRAIN-DEVELOPMENT | JNK PATHWAY | DEVELOPING CEREBRAL-CORTEX | DOUBLECORTIN-LIKE-KINASE | NEUROSCIENCES | Paclitaxel - pharmacology | Neurites - physiology | Tubulin Modulators - pharmacology | Male | Neurons - cytology | Axons - physiology | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Drug Interactions | Transfection - methods | Microtubules - drug effects | Female | Mitogen-Activated Protein Kinase 8 - genetics | RNA Interference - physiology | Neurites - drug effects | Physical Stimulation | MAP Kinase Kinase Kinases - genetics | Mice, Inbred C57BL | Mitogen-Activated Protein Kinase 8 - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Microtubules - physiology | Axons - drug effects | Gene Expression Regulation - physiology | Mice, Transgenic | MAP Kinase Kinase Kinases - metabolism | Signal Transduction - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Cell Polarity - genetics | Animals | Signal Transduction - drug effects | Models, Biological | Embryo, Nonmammalian | Neocortex - cytology | Signal Transduction - physiology | Mice | Antibodies, Monoclonal - metabolism | In Vitro Techniques | Neurofilament Proteins - metabolism | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2008, Volume 40, Issue 6, pp. 782 - 788
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0126942 - e0126942
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2006, Volume 26, Issue 46, pp. 11992 - 12002
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2006, Volume 26, Issue 51, pp. 13357 - 13362
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 10/1998, Volume 143, Issue 1, pp. 95 - 106
Journal Article
Journal Article
DEVELOPMENT, ISSN 0950-1991, 05/2006, Volume 133, Issue 9, pp. 1735 - 1735
In developing mammalian telencephalon, the loss of adherens junctions and cell cycle exit represent crucial steps in the differentiation of neuroepithelial... 
PROGENITOR CELLS | PROTEIN-KINASE-C | STEM-CELLS | PKC-LAMBDA | SMALL-MOLECULE | RETINAL LAMINATION | ATYPICAL PKC | EPITHELIAL POLARITY | aPKC | DEVELOPMENTAL BIOLOGY | brain | adherens junction | DEVELOPING TELENCEPHALON | neurogenesis | cell polarity | NEURONS ARISE
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1996, Volume 271, Issue 38, pp. 23512 - 23519
Although the involvement of protein kinase C (PKC) in the activation of the mitogen-activated protein (MAP) kinase pathway has been implicated through... 
RESPONSE ELEMENT | TRANSCRIPTIONAL ACTIVATION | IN-VITRO | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH-FACTORS | NPKC-EPSILON | BETA-GAMMA-SUBUNITS | REGULATORY DOMAIN | PHORBOL ESTERS | SIGNAL-TRANSDUCTION PATHWAY
Journal Article