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1. Full Text Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance
by Szakács, Gergely and Hall, Matthew D and Gottesman, Michael M and Boumendjel, Ahcène and Kachadourian, Remy and Day, Brian J and Baubichon-Cortay, Hélène and Di Pietro, Attilio
Chemical reviews, ISSN 0009-2665, 06/2014, Volume 114, Issue 11, pp. 5753 - 5774
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Neoplasms - genetics | Drug Resistance, Multiple - drug effects | Humans | Neoplasm Proteins - genetics | Neoplasms - pathology | Molecular Targeted Therapy - methods | Neoplasms - drug therapy | Care and treatment | Research | Drug resistance | Cancer | Chemotherapy | Toxicity | Index Medicus | Heels | Fitness | Review
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2. Full Text Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1
by Szöllősi, Dániel and Szakács, Gergely and Chiba, Peter and Stockner, Thomas
Biophysical journal, ISSN 0006-3495, 01/2018, Volume 114, Issue 2, pp. 331 - 342
Life Sciences & Biomedicine | Biophysics | Science & Technology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Protein Multimerization | Protein Structure, Quaternary | Models, Molecular | Protein Binding | Protein Domains | Nucleotides - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 - chemistry | Drug resistance in microorganisms | Chemotherapy | Nucleotides | Analysis | Cancer | Drugs | Switches | Amino acids | Activation | Hydrophobicity | Hydrogen bonding | Molecules | Conserved sequence | Hydrogen bonds | Energy | Chemical bonds | P-Glycoprotein | Dimerization | Adenosine triphosphate | Binding | Translocation | Multidrug resistance | Adenine | Glycoproteins | Electrostatic properties | Substrates | Simulation | Transmembrane domains | ATP | Transporter | Protein structure | Binding sites | Cytoplasm | Adenosine triphosphatase | Index Medicus | Channels and Transporters
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3. Full Text Heterologous expression of CTP: Phosphocholine cytidylyltransferase from Plasmodium falciparum rescues Chinese Hamster Ovary cells deficient in the Kennedy phosphatidylcholine biosynthesis pathway
by Marton, Lívia and Hajdú, Fanni and Nagy, Gergely N and Kucsma, Nóra and Szakács, Gergely and Vértessy, Beáta G
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8932 - 8
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Flow cytometry | CTP:phosphocholine | Lecithin | Developmental stages | Temperature-sensitive mutant | Cytidylyltransferase | High-throughput screening | Biosynthesis | Phosphocholine | Index Medicus
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4. Full Text An inventory of lysosomal ABC transporters
by Szakacs, Gergely and Abele, Rupert
FEBS letters, ISSN 0014-5793, 12/2020, Volume 594, Issue 23, pp. 3965 - 3985
endolysosomal system | peptide transport | cholesterol | ABC transporters | lysosomes | vitamin B12 | drug resistance | lipid | trafficking | surfactant | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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5. Full Text Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins
by Langó, Tamás and Róna, Gergely and Hunyadi-Gulyás, Éva and Turiák, Lilla and Varga, Julia and Dobson, László and Várady, György and Drahos, László and Vértessy, Beáta G and Medzihradszky, Katalin F and Szakács, Gergely and Tusnády, Gábor E
Scientific reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, pp. 42610 - 42610
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tandem Mass Spectrometry | Reproducibility of Results | Membrane Proteins - chemistry | Peptides - chemistry | Humans | Chromatography, Liquid | Models, Molecular | Protein Conformation | Protein Interaction Domains and Motifs | Structure-Activity Relationship | Proteins | Algorithms | Computer applications | Mass spectroscopy | Biotin | Kinetics | Nutrient uptake | Membrane proteins | Index Medicus
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6. Full Text Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System
by Balázs Sarkadi and László Homolya and Gergely Szakács and András Váradi
Physiological Reviews, ISSN 0031-9333, 10/2006, Volume 86, Issue 4, pp. 1179 - 1236
Life Sciences & Biomedicine | Physiology | Science & Technology | Amino Acid Sequence | Immune System - physiology | Humans | Organic Anion Transporters - chemistry | Multidrug Resistance-Associated Proteins - chemistry | Molecular Sequence Data | Organic Anion Transporters - immunology | Structure-Activity Relationship | ATP-Binding Cassette Transporters - chemistry | Organic Anion Transporters - genetics | Animals | ATP-Binding Cassette Transporters - genetics | Neoplasms - immunology | Multidrug Resistance-Associated Proteins - immunology | Multidrug Resistance-Associated Proteins - genetics | Neoplasms - physiopathology | ATP-Binding Cassette Transporters - immunology | Drug resistance | Adenosine triphosphate | Research | Studies | Proteins | ABC transporters | Biochemistry | Cellular biology | Index Medicus
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