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pseudomonas aeruginosa (10) 10
organic chemistry (9) 9
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pqs (3) 3
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catalyzes cyclodimerization (2) 2
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factor lasb (2) 2
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growth (2) 2
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menachinon-analoga (2) 2
menaquinone analogue (2) 2
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oxides (2) 2
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putrebactin (2) 2
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quorum-sensing systems (2) 2
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to-cell communication (2) 2
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Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 07/2018, Volume 84, Issue 13
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 07/2018, Volume 84, Issue 13, p. e00745-18
Only a small fraction of bacteria can autonomously initiate growth on agar plates. Nongrowing bacteria typically enter a metabolically inactive dormant state... 
Pathogens | Carbohydrates | Fractionation | Purification | Disaccharides | Agar | Oligosaccharides | Sulfation | Organic chemistry | Polysaccharides | Bacteria | Carrageenan | Sulfate | Molecular biology | D-Galactose | Sugars | Saccharides | Resuscitation | Carrageenans
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 4/2018, Volume 16, Issue 16, pp. 2814 - 2819
Bacteria engage in numerous collaborative and competitive interactions, which are often mediated by small molecule metabolites. Bacterial competition involves... 
SMALL-COLONY VARIANTS | CATALYZES CYCLODIMERIZATION | PSEUDOMONAS-AERUGINOSA | BIOSYNTHESIS | PUTREBACTIN | CHEMISTRY, ORGANIC | STAPHYLOCOCCUS-AUREUS | SIDEROPHORE | IDENTIFICATION | VIRULENCE | VIBRIO | Competition | Water-borne diseases | Siderophores | Secretion | Algae | Oxides | Iron | Metabolites | Antibiotics | Bacteria | Pseudomonas aeruginosa | N-Oxides | Vibrio
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2017, Volume 56, Issue 25, pp. 7005 - 7005
Chemical interactions of competing bacteria have major implications for health and disease of their human host. In their Communication on page 7271 ff., D.... 
Pseudomonas aeruginosa | virulence inhibition | menaquinone analogue | MRSA | AQNO | Chemical interactions | Bacteria | Virulence
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 11/2016, Volume 52, Issue 92, pp. 13440 - 13443
We explore the chemical space of Pseudomonas quinolone signal analogs as privileged structures and report the discovery of a thioquinolone as a potent... 
Pathogens | Virulence | Pseudomonas aeruginosa | Elastase | Derivatives | Pseudomonas | Zinc
Journal Article
ISSN 2041-6520, 7/2019, Volume 1, Issue 27, pp. 6624 - 6628
The Pseudomonas quinolone signal (PQS) is an important quorum sensing signal of the pathogen Pseudomonas aeruginosa . We discovered an additional activity of... 
Journal Article
Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 12/2016, Volume 12, Issue 1, pp. 2784 - 2792
The human pathogen Pseudomonas aeruginosa uses the pqs quorum sensing system to coordinate the production of its broad spectrum of virulence factors to... 
Pseudomonas aeruginosa | Protein labelling | PqsD | Activity-based probes | Quinolones | INFECTIONS | MECHANISM | ACIDS | ANALOGS | CHEMISTRY, ORGANIC | MOLECULES | ENZYME | activity-based probes | PATHWAY | protein labelling | BIOSYNTHESIS | FAMILIES | quinolones | INHIBITORS
Journal Article
Angewandte Chemie, ISSN 0044-8249, 06/2017, Volume 129, Issue 25, pp. 7109 - 7109
Journal Article
Angewandte Chemie, ISSN 0044-8249, 06/2017, Volume 129, Issue 25, pp. 7109 - 7109
Chemische Wechselwirkungen zwischen konkurrierenden Bakterien sind von großer Bedeutung für den Verlauf von Erkrankungen des Menschen. D. Szamosvári und T.... 
Pathogens | Pseudomonas aeruginosa
Journal Article
Angewandte Chemie, ISSN 0044-8249, 06/2017, Volume 129, Issue 25, pp. 7377 - 7381
Das Humanpathogen Pseudomonas aeruginosa produziert über 50 verschiedene Chinolone, von denen 16 zur Klasse der 2‐Alkyl‐4‐chinolon‐N‐oxide (AQNOs) gehören, die... 
Pathogens | Pseudomonas aeruginosa | Drug resistance
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 27, pp. 6624 - 6628
The Pseudomonas quinolone signal (PQS) is an important quorum sensing signal of the pathogen Pseudomonas aeruginosa. We discovered an additional activity of... 
Pathogens | Depletion | Antibiotics | Pseudomonas aeruginosa | Selectivity | Optimization
Journal Article
ISSN 1359-7345, 11/2016, Volume 52, Issue 92, pp. 1344 - 13443
We explore the chemical space of Pseudomonas quinolone signal analogs as privileged structures and report the discovery of a thioquinolone as a potent... 
Journal Article
ISSN 1359-7345, 6/2019, Volume 55, Issue 49, pp. 79 - 712
Expanding the chemical space of quinolones led to a tandem quinolone-alkyne-cyclisation reaction allowing chemoselective control of the synthesis of tricyclic... 
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2019, Volume 55, Issue 49, pp. 7009 - 7012
Expanding the chemical space of quinolones led to a tandem quinolone-alkyne-cyclisation reaction allowing chemoselective control of the synthesis of tricyclic... 
Organic chemistry | Malaria | Alkynes
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 04/2018, Volume 16, Issue 16, pp. 2814 - 2819
Bacteria engage in numerous collaborative and competitive interactions, which are often mediated by small molecule metabolites. Bacterial competition involves... 
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 2016, Volume 52, Issue 92, pp. 13440 - 13443
We explore the chemical space of Pseudomonas quinolone signal analogs as privileged structures and report the discovery of a thioquinolone as a potent... 
INFECTIONS | PQS | TO-CELL COMMUNICATION | MODULATORS | CHELATOR | CHEMISTRY, MULTIDISCIPLINARY | CYCLIZATION | DISCOVERY | QUORUM-SENSING SYSTEMS | FACTOR LASB | INSIGHTS
Journal Article
CHEMICAL SCIENCE, ISSN 2041-6520, 07/2019, Volume 10, Issue 27, pp. 6624 - 6628
The Pseudomonas quinolone signal (PQS) is an important quorum sensing signal of the pathogen Pseudomonas aeruginosa. We discovered an additional activity of... 
HHQ | BACTERIA | PQS | VIRULENCE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 49, pp. 7009 - 7012
Expanding the chemical space of quinolones led to a tandem quinolone-alkyne-cyclisation reaction allowing chemoselective control of the synthesis of tricyclic... 
RESPIRATORY-CHAIN | PLASMODIUM-FALCIPARUM | GROWTH | TOXOPLASMA-GONDII | ANTIMALARIALS | INHIBITORS | FUROQUINOLINE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
Journal Article
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