Frontiers in Immunology, ISSN 1664-3224, 2018, Volume 9, p. 2153
We conducted a prospective study of 312 patients (194 with multiple myeloma, 118 with lymphomas) receiving high-dose conditioning chemotherapy and autologous...
CL-LK | MASP | Mannose-binding lectin (MBL) | Collectin | Complement | Lymphoma | Mutliple myeloma | Hematopoietic stem cell transplantation (HSCT) | MULTIPLE-MYELOMA | MANNOSE-BINDING LECTIN | lymphoma | mutliple myeloma | RISK | IMMUNOLOGY | collectin | hematopoistic stem cell transplantation (HSCT) | LARGE COHORT | DEFICIENCY | PATHWAY | NON-HODGKIN-LYMPHOMA | STEM/PROGENITOR CELLS | mannose-binding lectin (MBL) | complement | SEVERE INFECTIONS | INNATE IMMUNITY | Chemotherapy | Usage | Care and treatment | Proteases | Serine | Transplantation | Research | Blood diseases | Hematopoietic stem cells | Cancer | hematopoietic stem cell transplantation (HSCT)
CL-LK | MASP | Mannose-binding lectin (MBL) | Collectin | Complement | Lymphoma | Mutliple myeloma | Hematopoietic stem cell transplantation (HSCT) | MULTIPLE-MYELOMA | MANNOSE-BINDING LECTIN | lymphoma | mutliple myeloma | RISK | IMMUNOLOGY | collectin | hematopoistic stem cell transplantation (HSCT) | LARGE COHORT | DEFICIENCY | PATHWAY | NON-HODGKIN-LYMPHOMA | STEM/PROGENITOR CELLS | mannose-binding lectin (MBL) | complement | SEVERE INFECTIONS | INNATE IMMUNITY | Chemotherapy | Usage | Care and treatment | Proteases | Serine | Transplantation | Research | Blood diseases | Hematopoietic stem cells | Cancer | hematopoietic stem cell transplantation (HSCT)
Journal Article
Annals of Hematology, ISSN 0939-5555, 12/2017, Volume 96, Issue 12, pp. 2103 - 2112
As a site of complicated interactions among cytokines, bone marrow niche has been the subject of many scientific studies, mainly in the context of the proteins...
Medicine & Public Health | Hematology | Angiopoietin | VEGF | Engraftment | Oncology | MMP-9 | Hematopoietic stem cell transplantation (HSCT) | MULTIPLE-MYELOMA | PROGENITOR CELLS | SURVIVAL | RECRUITMENT | MOBILIZATION | BONE-MARROW NICHE | BLOOD-VESSEL FORMATION | ANGIOPOIETIN-1 | TUMOR ANGIOGENESIS | HEMATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Hematologic Neoplasms - therapy | Vascular Endothelial Growth Factor A - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Neoplasm Proteins - biosynthesis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Angiopoietin-2 - biosynthesis | Hematopoietic Stem Cell Transplantation | Male | Lymphoma - blood | Multiple Myeloma - therapy | Lymphoma - therapy | Hematologic Neoplasms - blood | Adult | Female | Aged | Angiopoietin-1 - biosynthesis | Multiple Myeloma - blood | Bone marrow | Transplantation | Endothelial growth factors | Hematopoietic stem cells | Multiple myeloma | Stem cells | Transplants & implants | Cytokines
Medicine & Public Health | Hematology | Angiopoietin | VEGF | Engraftment | Oncology | MMP-9 | Hematopoietic stem cell transplantation (HSCT) | MULTIPLE-MYELOMA | PROGENITOR CELLS | SURVIVAL | RECRUITMENT | MOBILIZATION | BONE-MARROW NICHE | BLOOD-VESSEL FORMATION | ANGIOPOIETIN-1 | TUMOR ANGIOGENESIS | HEMATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Hematologic Neoplasms - therapy | Vascular Endothelial Growth Factor A - biosynthesis | Matrix Metalloproteinase 9 - biosynthesis | Neoplasm Proteins - biosynthesis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Angiopoietin-2 - biosynthesis | Hematopoietic Stem Cell Transplantation | Male | Lymphoma - blood | Multiple Myeloma - therapy | Lymphoma - therapy | Hematologic Neoplasms - blood | Adult | Female | Aged | Angiopoietin-1 - biosynthesis | Multiple Myeloma - blood | Bone marrow | Transplantation | Endothelial growth factors | Hematopoietic stem cells | Multiple myeloma | Stem cells | Transplants & implants | Cytokines
Journal Article
European Journal of Haematology, ISSN 0902-4441, 05/2018, Volume 100, Issue 5, pp. 426 - 435
Objective MicroRNAs engaged in angiogenesis and hematopoiesis can influence hematopoietic stem cells (HSCs) homing after transplantation by targeting bone...
engraftment | miRNA | multiple myeloma | hematopoietic stem cells transplantation | lymphoma | MULTIPLE-MYELOMA | PROGENITOR CELLS | COLONY-STIMULATING FACTOR | ANGIOGENESIS | ANGIOPOIETIN-1 | CANCER | ADHESION MOLECULE-1 | DIFFERENTIATION | BONE | HEMATOLOGY | MICRORNA EXPRESSION | Medical research | Chemotherapy | MicroRNA | Multiple myeloma | Stem cells | Bone marrow | Medicine, Experimental | Transplantation | Lymphomas | Hematopoietic stem cells | Cancer | Autografts | Angiogenesis | Transplants & implants | MicroRNAs | MiRNA | Bone marrow transplantation | Stem cell transplantation | Lymphoma | Cell migration
engraftment | miRNA | multiple myeloma | hematopoietic stem cells transplantation | lymphoma | MULTIPLE-MYELOMA | PROGENITOR CELLS | COLONY-STIMULATING FACTOR | ANGIOGENESIS | ANGIOPOIETIN-1 | CANCER | ADHESION MOLECULE-1 | DIFFERENTIATION | BONE | HEMATOLOGY | MICRORNA EXPRESSION | Medical research | Chemotherapy | MicroRNA | Multiple myeloma | Stem cells | Bone marrow | Medicine, Experimental | Transplantation | Lymphomas | Hematopoietic stem cells | Cancer | Autografts | Angiogenesis | Transplants & implants | MicroRNAs | MiRNA | Bone marrow transplantation | Stem cell transplantation | Lymphoma | Cell migration
Journal Article
Developmental period medicine, ISSN 1428-345X, 2017, Volume 21, Issue 2, p. 139
Sterile leukocyturia is an important and difficult clinical problem in children. In this paper, we described the most common nephrologic causes of sterile...
Urination Disorders - diagnosis | Urination Disorders - urine | Humans | Urination Disorders - etiology | Female | Male | Leukocytes | Urinary Tract Infections - complications | Child | Urinalysis - methods
Urination Disorders - diagnosis | Urination Disorders - urine | Humans | Urination Disorders - etiology | Female | Male | Leukocytes | Urinary Tract Infections - complications | Child | Urinalysis - methods
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5717 - 5717
Abstract Introduction MicroRNAs are a class of small (19-25 nucleotides), endogenous RNA which play a significant role in regulation of gene expressions, cell...
Journal Article
Leukemia & Lymphoma, ISSN 1042-8194, 10/2019, pp. 1 - 16
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 213 - 213
Abstract Objectives The treatment results of acute myeloid leukemia (AML) patients (pts) younger than 60yo are still unsatisfactory. The strategy of double...
Journal Article
Annals of Hematology, ISSN 0939-5555, 9/2013, Volume 92, Issue 9, pp. 1255 - 1262
In neoplastic disorders, endothelial cells take part in tumor progression and also influence the recovery of hematopoiesis after high-dose chemotherapy....
Engraftment | Oncology | Circulating endothelial cells | Medicine & Public Health | Hematology | Autologous hematopoietic stem cell transplantation | MULTIPLE-MYELOMA | PROGENITOR CELLS | ANGIOGENESIS | TUMOR | PERIPHERAL-BLOOD | ACUTE MYELOID-LEUKEMIA | CHEMOTHERAPY | BREAST-CANCER | CANCER-PATIENTS | HEMATOLOGY | RECONSTITUTION | Lymphoproliferative Disorders - surgery | Flow Cytometry - methods | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Male | Hematopoietic Stem Cells - metabolism | Lymphoproliferative Disorders - pathology | Endothelium, Vascular - metabolism | Adult | Endothelium, Vascular - pathology | Female | Aged | Apoptosis - physiology | Hematopoietic Stem Cell Transplantation - methods | Kinetics | Care and treatment | Chemotherapy | Analysis | Multiple myeloma | Stem cells | Development and progression | Lymphomas | Transplantation | Hematopoietic stem cells | Apoptosis | Endothelium | Cancer
Engraftment | Oncology | Circulating endothelial cells | Medicine & Public Health | Hematology | Autologous hematopoietic stem cell transplantation | MULTIPLE-MYELOMA | PROGENITOR CELLS | ANGIOGENESIS | TUMOR | PERIPHERAL-BLOOD | ACUTE MYELOID-LEUKEMIA | CHEMOTHERAPY | BREAST-CANCER | CANCER-PATIENTS | HEMATOLOGY | RECONSTITUTION | Lymphoproliferative Disorders - surgery | Flow Cytometry - methods | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Male | Hematopoietic Stem Cells - metabolism | Lymphoproliferative Disorders - pathology | Endothelium, Vascular - metabolism | Adult | Endothelium, Vascular - pathology | Female | Aged | Apoptosis - physiology | Hematopoietic Stem Cell Transplantation - methods | Kinetics | Care and treatment | Chemotherapy | Analysis | Multiple myeloma | Stem cells | Development and progression | Lymphomas | Transplantation | Hematopoietic stem cells | Apoptosis | Endothelium | Cancer
Journal Article
Journal of Clinical Apheresis, ISSN 0733-2459, 08/2015, Volume 30, Issue 4, pp. 247 - 251
The bone marrow niche functions are modulated by complicated cytokines network. The aim of our study was to evaluate the levels of VCAM‐1, VEGF, MMP‐9 and SDF...
cytokines | mobilization | hematopoietic stem cells | apheresis | MULTIPLE-MYELOMA | COLONY-STIMULATING FACTOR | REGENERATION | BONE-MARROW | G-CSF | STEM-CELL MOBILIZATION | TRANSPLANTATION | HEALTHY DONORS | HEMATOLOGY | OSTEOBLASTIC NICHE | BLOOD | Hematologic Neoplasms - therapy | Stem Cell Niche - immunology | Antigens, CD34 - metabolism | Humans | Middle Aged | Blood Component Removal - methods | Male | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Lymphoma - blood | Matrix Metalloproteinase 9 - metabolism | Multiple Myeloma - therapy | Lymphoma - therapy | Adult | Female | Hematopoietic Stem Cell Mobilization | Granulocyte Colony-Stimulating Factor - metabolism | Multiple Myeloma - blood | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Hematopoietic Stem Cell Transplantation | Hematologic Neoplasms - blood | Hematopoietic Stem Cells - cytology | Aged | Kinetics | Vascular Cell Adhesion Molecule-1 - metabolism | Care and treatment | Chemotherapy | Cytokines | Vascular endothelial growth factor | Multiple myeloma | Cancer
cytokines | mobilization | hematopoietic stem cells | apheresis | MULTIPLE-MYELOMA | COLONY-STIMULATING FACTOR | REGENERATION | BONE-MARROW | G-CSF | STEM-CELL MOBILIZATION | TRANSPLANTATION | HEALTHY DONORS | HEMATOLOGY | OSTEOBLASTIC NICHE | BLOOD | Hematologic Neoplasms - therapy | Stem Cell Niche - immunology | Antigens, CD34 - metabolism | Humans | Middle Aged | Blood Component Removal - methods | Male | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Lymphoma - blood | Matrix Metalloproteinase 9 - metabolism | Multiple Myeloma - therapy | Lymphoma - therapy | Adult | Female | Hematopoietic Stem Cell Mobilization | Granulocyte Colony-Stimulating Factor - metabolism | Multiple Myeloma - blood | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Hematopoietic Stem Cell Transplantation | Hematologic Neoplasms - blood | Hematopoietic Stem Cells - cytology | Aged | Kinetics | Vascular Cell Adhesion Molecule-1 - metabolism | Care and treatment | Chemotherapy | Cytokines | Vascular endothelial growth factor | Multiple myeloma | Cancer
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 4797 - 4797
BACKGROUND Nomacopan, a small protein biologic previously known as Coversin (AK576), is in Phase III clinical development for PNH. Patients completing COBALT,...
Journal Article
Journal of Clinical Apheresis, ISSN 0733-2459, 10/2013, Volume 28, Issue 5, pp. 341 - 348
Objective: Circulating endothelial cells (CECs) in patients with hematological malignancies are assessed as a noninvasive marker of angiogenesis. The aim of...
hematopoietic stem cells mobilization | circulating endothelial cells | efficacy | PROGENITOR CELLS | MULTIPLE-MYELOMA | BLOOD STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | PERIPHERAL-BLOOD | HEALTHY DONORS | CANCER-PATIENTS | HSC NICHES | HEMATOLOGY | OSTEOBLASTIC NICHE | MARROW VASCULAR NICHE | Antigens, CD34 - metabolism | Leukocyte Common Antigens - metabolism | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Glycoproteins - metabolism | Neovascularization, Pathologic | Male | Blood Component Removal | Case-Control Studies | Antigens, CD - metabolism | Young Adult | Multiple Myeloma - therapy | Flow Cytometry | Lymphoma - therapy | Peptides - metabolism | Time Factors | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Adult | Female | Granulocyte Colony-Stimulating Factor - metabolism | Leukemia, Myeloid, Acute - therapy | Cell Separation | AC133 Antigen | Annexin A5 - metabolism | Endothelial Cells - cytology | Hematopoietic Stem Cells - cytology | Aged | Apoptosis | Chemotherapy | Leukemia | Hematopoietic stem cells | Cancer | Endothelium
hematopoietic stem cells mobilization | circulating endothelial cells | efficacy | PROGENITOR CELLS | MULTIPLE-MYELOMA | BLOOD STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | PERIPHERAL-BLOOD | HEALTHY DONORS | CANCER-PATIENTS | HSC NICHES | HEMATOLOGY | OSTEOBLASTIC NICHE | MARROW VASCULAR NICHE | Antigens, CD34 - metabolism | Leukocyte Common Antigens - metabolism | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Glycoproteins - metabolism | Neovascularization, Pathologic | Male | Blood Component Removal | Case-Control Studies | Antigens, CD - metabolism | Young Adult | Multiple Myeloma - therapy | Flow Cytometry | Lymphoma - therapy | Peptides - metabolism | Time Factors | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Adult | Female | Granulocyte Colony-Stimulating Factor - metabolism | Leukemia, Myeloid, Acute - therapy | Cell Separation | AC133 Antigen | Annexin A5 - metabolism | Endothelial Cells - cytology | Hematopoietic Stem Cells - cytology | Aged | Apoptosis | Chemotherapy | Leukemia | Hematopoietic stem cells | Cancer | Endothelium
Journal Article
Pediatria i Medycyna Rodzinna, ISSN 1734-1531, 05/2019, Volume 15, Issue 1, pp. 22 - 25
Journal Article
Developmental period medicine, ISSN 1428-345X, 07/2015, Volume 19, Issue 3, pp. 351 - 355
Improvement in the quality of life in Europe and North America in last decades caused that economical and social aspects of living conditions of the population...
Malabsorption Syndromes - diagnosis | Prognosis | Vitamin B 12 Deficiency - diagnosis | Humans | Child, Preschool | Male | Treatment Outcome | Rare Diseases | Vitamin B 12 Deficiency - drug therapy | Vitamin B 12 - therapeutic use | Proteinuria - drug therapy | Anemia, Megaloblastic - diagnosis | Anemia, Megaloblastic - drug therapy | Female | Proteinuria - diagnosis | Malabsorption Syndromes - drug therapy | Child | Siblings
Malabsorption Syndromes - diagnosis | Prognosis | Vitamin B 12 Deficiency - diagnosis | Humans | Child, Preschool | Male | Treatment Outcome | Rare Diseases | Vitamin B 12 Deficiency - drug therapy | Vitamin B 12 - therapeutic use | Proteinuria - drug therapy | Anemia, Megaloblastic - diagnosis | Anemia, Megaloblastic - drug therapy | Female | Proteinuria - diagnosis | Malabsorption Syndromes - drug therapy | Child | Siblings
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2017, Volume 376, Issue 8, pp. 742 - 754
A third of patients with the DiGeorge syndrome have congenital kidney and urinary tract anomalies. This study provides evidence that haploinsufficiency of CRKL...
Medicine(all) | MORPHOGENESIS | MEDICINE, GENERAL & INTERNAL | MALFORMATIONS | LOW COPY REPEATS | MOUSE | DISORDERS | 22Q11.2 DELETION SYNDROME | TBX1 HAPLOINSUFFICIENCY | MUTATIONS | MICE LACKING | CRKL | Chromosome Deletion | Humans | Infant | Male | Urinary Tract - abnormalities | Zebrafish | Sequence Analysis, DNA | Haploinsufficiency | Exome | Young Adult | Animals | Kidney - abnormalities | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Female | Heterozygote | Models, Animal | Chromosomes, Human, Pair 22 | Mice | Nuclear Proteins - genetics | Child | DiGeorge Syndrome - genetics | Infant, Newborn | Genetics | Care and treatment | Diagnosis | Kidney diseases | Research | DiGeorge syndrome | Phenotypes | Kidneys | Nonsense mutation | Nervous system | Urinary tract | Gene deletion | Embryos | Defects | Clonal deletion | Chromosome 22 | Thymic hypoplasia | Urogenital system | Chromosomes
Medicine(all) | MORPHOGENESIS | MEDICINE, GENERAL & INTERNAL | MALFORMATIONS | LOW COPY REPEATS | MOUSE | DISORDERS | 22Q11.2 DELETION SYNDROME | TBX1 HAPLOINSUFFICIENCY | MUTATIONS | MICE LACKING | CRKL | Chromosome Deletion | Humans | Infant | Male | Urinary Tract - abnormalities | Zebrafish | Sequence Analysis, DNA | Haploinsufficiency | Exome | Young Adult | Animals | Kidney - abnormalities | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Female | Heterozygote | Models, Animal | Chromosomes, Human, Pair 22 | Mice | Nuclear Proteins - genetics | Child | DiGeorge Syndrome - genetics | Infant, Newborn | Genetics | Care and treatment | Diagnosis | Kidney diseases | Research | DiGeorge syndrome | Phenotypes | Kidneys | Nonsense mutation | Nervous system | Urinary tract | Gene deletion | Embryos | Defects | Clonal deletion | Chromosome 22 | Thymic hypoplasia | Urogenital system | Chromosomes
Journal Article
Central European Journal of Immunology, ISSN 1426-3912, 2016, Volume 41, Issue 3, pp. 260 - 267
Urinary tract infection (UTI) occurs in 1.1% of girls and 1.4% of boys during the first year of life. Asymptomatic bacteriuria (ABU) is usually detected...
Asymptomatic bacteriuria | Urinary tract infection | Transforming growth factor β1 | Interleukin-8 | Interleukin-6 | Clinical Immunology | interleukin-8 | asymptomatic bacteriuria | transforming growth factor β1 | urinary tract infection | interleukin-6
Asymptomatic bacteriuria | Urinary tract infection | Transforming growth factor β1 | Interleukin-8 | Interleukin-6 | Clinical Immunology | interleukin-8 | asymptomatic bacteriuria | transforming growth factor β1 | urinary tract infection | interleukin-6
Journal Article
Developmental period medicine, ISSN 1428-345X, 2018, Volume 22, Issue 4, pp. 371 - 375
Journal Article
Developmental period medicine, ISSN 1428-345X, 2018, Volume 22, Issue 4, p. 371
The incidence of horseshoe kidney is 1 per 400-800 live births. From 44-52% of the patients with horseshoe kidney have other coexisting abnormalities of the...
Journal Article
Archives of Medical Science, ISSN 1734-1922, 2019
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 3270 - 3270
Abstract Background In the last decade peripheral blood was the main source of hematopoietic stem cells (HSC) for autologous (auto-SCT) and allogeneic...
Journal Article
CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY, ISSN 1426-3912, 2019, Volume 44, Issue 3, pp. 262 - 268
Introduction: Kidney injury molecule-1 (KIM-1) is an important diagnostic and prognostic marker in acute kidney injury and chronic kidney disease of various...
NGAL | EARLY-DIAGNOSIS | biomarkers | GELATINASE-ASSOCIATED LIPOCALIN | IMMUNOLOGY | kidney injury molecule-1 | REFERENCE INTERVALS | KIM-1 | GESTATIONAL-AGE | children | acute kidney injury | urinary tract infection | BLOOD
NGAL | EARLY-DIAGNOSIS | biomarkers | GELATINASE-ASSOCIATED LIPOCALIN | IMMUNOLOGY | kidney injury molecule-1 | REFERENCE INTERVALS | KIM-1 | GESTATIONAL-AGE | children | acute kidney injury | urinary tract infection | BLOOD
Journal Article