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1. Full Text Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
by Nathalie Gaborit and Sabrina Le Bouter and Viktoria Szuts and Andras Varro and Denis Escande and Stanley Nattel and Sophie Demolombe
The Journal of Physiology, ISSN 0022-3751, 07/2007, Volume 582, Issue 2, pp. 675 - 693
The various cardiac regions have specific action potential properties appropriate to their electrical specialization, resulting from a specific pattern of... 
TRANSMURAL HETEROGENEITY | PHYSIOLOGY | TRANSIENT OUTWARD CURRENT | POTASSIUM CURRENTS | CURRENT I-TO | MESSENGER-RNA | CARDIAC PURKINJE-FIBERS | RECTIFIER K+ CURRENT | VENTRICULAR-WALL | DIFFERENTIAL DISTRIBUTION | NEUROSCIENCES | HUMAN ATRIAL MYOCYTES | Heart Atria | Humans | Middle Aged | Ion Channels - genetics | Male | Reference Values | Pericardium - metabolism | Purkinje Fibers - metabolism | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Endocardium - metabolism | Heart Ventricles | Tissue Distribution | Carrier Proteins - genetics | Ion Channels - metabolism | Myocardium - metabolism | Adult | Female | Transcription, Genetic | Cluster Analysis | Protein Isoforms - genetics | Genetic research | Calcium channels | Cardiovascular
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2. Full Text Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts
by Gaborit, Nathalie and Varro, Andras and Le Bouter, Sabrina and Szuts, Viktoria and Escande, Denis and Nattel, Stanley and Demolombe, Sophie
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2010, Volume 49, Issue 4, pp. 639 - 646
Abstract Gender-related differences in ventricular electrophysiology are known to be important determinants of human arrhythmic risk, but the underlying... 
Cardiovascular | Long QT syndrome | Brugada syndrome | Ion-channels | Sex | SCN5A MUTATION | DE-POINTES | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC CONDUCTION DEFECT | K+ CURRENTS | REPOLARIZATION | CELL BIOLOGY | BRUGADA-SYNDROME | TRANSIENT OUTWARD CURRENT | GENE-EXPRESSION | VENTRICULAR-WALL | SEX-DIFFERENCES | Connexin 43 - metabolism | Homeodomain Proteins - metabolism | Humans | Middle Aged | Ether-A-Go-Go Potassium Channels - metabolism | Immunoblotting | Male | Transcription Factors - genetics | ERG1 Potassium Channel | Ether-A-Go-Go Potassium Channels - genetics | Homeodomain Proteins - genetics | Potassium Channels - genetics | Long QT Syndrome - metabolism | Potassium Channels - metabolism | Transcription Factors - metabolism | Brugada Syndrome - metabolism | Ion Channels - metabolism | Myocardium - metabolism | Polymerase Chain Reaction | Adult | Female | In Vitro Techniques | Connexin 43 - genetics | DNA binding proteins | Analysis | Adenosine triphosphatase | Calmodulin
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3. Full Text Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs
by Jost, Norbert and Virág, László and Comtois, Philippe and Ördög, Balázs and Szuts, Viktória and Seprényi, György and Bitay, Miklós and Kohajda, Zsófia and Koncz, István and Nagy, Norbert and Szél, Tamás and Magyar, János and Kovács, Mária and Puskás, László G and Lengyel, Csaba and Wettwer, Erich and Ravens, Ursula and Nánási, Péter P and Papp, Julius Gy and Varró, András and Nattel, Stanley
The Journal of Physiology, ISSN 0022-3751, 09/2013, Volume 591, Issue 17, pp. 4189 - 4206
Key points •  Cardiac repolarization, through which heart‐cells return to their resting state after having fired, is a delicate process, susceptible to... 
LONG-QT | HEART | CELLULAR BASIS | PHYSIOLOGY | RABBIT | DIFFERENTIAL DISTRIBUTION | GUINEA-PIG | K+ CURRENTS | I-KS | EXPRESSION | NEUROSCIENCES | VENTRICULAR-MUSCLE | Potassium - metabolism | Species Specificity | Calcium - metabolism | Models, Cardiovascular | Heart - physiology | Humans | Middle Aged | RNA, Messenger - genetics | Cells, Cultured | Male | Sodium - metabolism | RNA, Messenger - metabolism | Potassium Channels - genetics | Action Potentials | Potassium Channels - metabolism | Animals | Myocytes, Cardiac - physiology | Sodium-Calcium Exchanger - metabolism | Dogs | Myocytes, Cardiac - metabolism | Adult | Female | Ion Transport | Research Papers
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4. Full Text Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues
by Dobrzynski, Halina and Anderson, Robert H and Atkinson, Andrew and Borbas, Zoltan and D'Souza, Alicia and Fraser, John F and Inada, Shin and Logantha, Sunil J.R.J and Monfredi, Oliver and Morris, Gwilym M and Moorman, Anton F.M and Nikolaidou, Thodora and Schneider, Heiko and Szuts, Viktoria and Temple, Ian P and Yanni, Joseph and Boyett, Mark R
Pharmacology and Therapeutics, ISSN 0163-7258, 08/2013, Volume 139, Issue 2, pp. 260 - 288
It is now over 100 years since the discovery of the cardiac conduction system, consisting of three main parts, the sinus node, the atrioventricular node and... 
Right ventricular outflow tract | Cardiac conduction system | Atrioventricular ring tissue | Channelopathies | Biopacemaking | Arrhythmias | HYPERPOLARIZATION-ACTIVATED CURRENT | TORSADES-DE-POINTES | SINUS NODE DYSFUNCTION | LONG-QT SYNDROME | BUNDLE-BRANCH-BLOCK | ARRHYTHMOGENIC PURKINJE-CELLS | CANINE VENTRICULAR-MUSCLE | FOCAL ATRIAL TACHYCARDIA | COMPUTER 3-DIMENSIONAL RECONSTRUCTION | PHARMACOLOGY & PHARMACY | HEART-RATE REDUCTION | Heart Conduction System - embryology | Animals | Heart Conduction System - physiology | Humans | Heart Conduction System - anatomy & histology | Ion Channels - genetics | Embryonic Development | Mutation
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5. Full Text Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases
by Gaborit, Nathalie and Wichter, Thomas and Varro, Andras and Szuts, Viktoria and Lamirault, Guillaume and Eckardt, Lars and Paul, Matthias and Breithardt, Günter and Schulze-Bahr, Eric and Escande, Denis and Nattel, Stanley and Demolombe, Sophie
European Heart Journal, ISSN 0195-668X, 2/2009, Volume 30, Issue 4, pp. 487 - 496
Aims Brugada syndrome is an inherited sudden-death arrhythmia syndrome. Na+-current dysfunction is central, but mutations in the SCN5A gene (encoding the... 
Ventricular tachycardia | Ion channels | Gene expression | Humans | CARDIAC & CARDIOVASCULAR SYSTEMS | MOUSE | MECHANISMS | GATED SODIUM-CHANNEL | REPOLARIZATION | CALCIUM | SUDDEN CARDIAC DEATH | ST-SEGMENT ELEVATION | HUMAN HEART | EXPRESSION | Brugada Syndrome - genetics | Brugada Syndrome - diagnosis | Brugada Syndrome - physiopathology | Middle Aged | Ion Channels - genetics | Male | Arrhythmogenic Right Ventricular Dysplasia - physiopathology | Arrhythmogenic Right Ventricular Dysplasia - genetics | Young Adult | Tachycardia, Ventricular - genetics | Adult | Female | NAV1.5 Voltage-Gated Sodium Channel | Gene Expression | Gene Expression Profiling - methods | Genotype | Mutation - genetics | Muscle Proteins - genetics | Phenotype | Tachycardia, Ventricular - physiopathology | Heart Ventricles - physiopathology | Heart Ventricles - metabolism | Sodium Channels - genetics | Transcription, Genetic - genetics
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6. Full Text In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart
by Bendahhou, Saïd and Marionneau, Céline and Haurogne, Karinne and Larroque, Marie-Madeleine and Derand, Renaud and Szuts, Viktoria and Escande, Denis and Demolombe, Sophie and Barhanin, Jacques
Cardiovascular Research, ISSN 0008-6363, 08/2005, Volume 67, Issue 3, pp. 529 - 538
Objective: The voltage-gated K channel KCNQ1 associates with the small KCNE1 β subunit to underlie the IKs repolarizing current in the heart. Based on sequence... 
Long QT syndrome | Repolarization | K channel | Arrhythmia | Membrane currents | PERIODIC PARALYSIS | OF-FUNCTION MUTATION | CARDIAC & CARDIOVASCULAR SYSTEMS | long QT syndrome | repolarization | CARDIAC-ARRHYTHMIA | POTASSIUM CHANNEL GENE | ATRIAL-FIBRILLATION | TARGETED DISRUPTION | membrane currents | arrhythmia | KVLQT1 | K+ CHANNEL | LANGE-NIELSEN-SYNDROME | INHIBITORY SUBUNIT | Cricetinae | KCNQ1 Potassium Channel - genetics | Heart Atria | Humans | Cercopithecus aethiops | RNA, Messenger - analysis | Reverse Transcriptase Polymerase Chain Reaction | Animals | Transfection - methods | Potassium Channels, Voltage-Gated - metabolism | Myocardium - metabolism | COS Cells | Ion Channel Gating | Potassium Channels, Voltage-Gated - genetics
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7. Full Text Altered expression of genes for kir ion channels in dilated cardiomyopathy
by Szuts, Viktoria and Ménesi, Dalma and Varga-Orvos, Zoltán and Zvara, Ágnes and Houshmand, Nazanin and Bitay, Miklós and Bogáts, Gábor and Virág, László and Baczkó, István and Szalontai, Balázs and Geramipoor, Amir and Cotella, Diego and Wettwer, Erich and Ravens, Ursula and Deák, Ferenc and Puskás, László G and Papp, Julius Gy and Kiss, Ibolya and Varró, András and Jost, Norbert
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2013, Volume 91, Issue 8, pp. 648 - 656
Dilated cardiomyopathy (DCM) is a multifactorial disease characterized by left ventricular dilation that is associated with systolic dysfunction and increased... 
SAP97 | Dilated cardiomyopathy | Inward rectifier potassium channels | Kir2.x | MYOCARDIUM | RECTIFYING POTASSIUM CHANNELS | PHYSIOLOGY | CURRENT I-K1 | PROTEIN | MYOCYTES | I-KR | I-K1 | CURRENTS | GUINEA-PIG HEART | PHARMACOLOGY & PHARMACY | inward rectifier potassium channels | K+ CHANNEL | CANINE | dilated cardiomyopathy | Cardiomyopathy, Dilated - genetics | Cardiomyopathy, Dilated - pathology | Gene Expression | Humans | Middle Aged | Male | Potassium Channels, Inwardly Rectifying - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cardiomyopathy, Dilated - metabolism | Blotting, Western | Young Adult | Myocytes, Cardiac - pathology | Patch-Clamp Techniques | Aging - genetics | Membrane Potentials | Protein Isoforms | Adolescent | Myocytes, Cardiac - metabolism | Adult | Female | Heart Ventricles - metabolism | Heart Ventricles - pathology | Cardiomyopathy | Physiological aspects | Genetic aspects | Ion channels | Research | Gene expression | Heart diseases | Health aspects | Action potential
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8. Effects of 6-epi-ophiobolin A on mechanical and physiological parameters of cardiomyocytes and on the reorganization and amounts of their kv4.x ion channels
by Szuts, Viktoria and ötvös, Ferenc and Bencsik, Ottó and Váró, György and Jarabin, János András and Kovács, András and Rovó, László and Kiss, József Géza and Szénási, Tibor and Véha, Antal and Szekeres, András and Vágvölgyi, Csaba and Halasy, Katalin and Szegletes, Zsolt
Acta Biologica Szegediensis, ISSN 1588-385X, 2016, Volume 60, Issue 2, pp. 157 - 166
Ophiobolin | Kv4.x ion channels | Nutrition | Cardiomyopathy | Transient outward current
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9. Full Text Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
: Regional ion channel subunit gene expression in the human heart
by Gaborit, Nathalie and Le Bouter, Sabrina and Szuts, Viktoria and Varro, Andras and Escande, Denis and Nattel, Stanley and Demolombe, Sophie
The Journal of Physiology, ISSN 0022-3751, 07/2007, Volume 582, Issue 2, pp. 675 - 693
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10. Altered expression of genes for Kir ion channels in dilated cardiomyopathy
by Viktoria Szuts and Dalma Ménesi and Zoltán Varga-Orvos and Ágnes Zvara and Nazanin Houshmand and Miklós Bitay and Gábor Bogáts and László Virág and István Baczkó and Balázs Szalontai and Amir Geramipoor and Diego Cotella and Erich Wettwer and Ursula Ravens and Ferenc Deák and László G Puskás and Julius Gy Papp and Ibolya Kiss and András Varró and Norbert Jost
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 08/2013, Volume 91, Issue 8, p. 648
Proteins | Cardiomyocytes | Iron | Gene expression
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11. Full Text Weaker contribution of IK1 current to the cardiac repolarization reserve in human versus dog ventricular muscle
by Jost, Norbert and Szűts, Viktoria and Virag, László and Seprényi, György and Szabad, János and Puskás, László and Gy, Julius
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2008, Volume 44, Issue 4, pp. 786 - 786
Cardiovascular
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12. Full Text Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
by Nagy, Norbert and Szűts, Viktória and Horváth, Zoltán and Seprényi, György and Farkas, Attila S and Acsai, Károly and Prorok, János and Bitay, Miklós and Kun, Attila and Pataricza, János and Papp, Julius Gy and Nánási, Péter P and Varró, András and Tóth, András
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2009, Volume 47, Issue 5, pp. 656 - 663
Abstract Small-conductance calcium-activated potassium channels (SK channels) have a significant role in neurons. Since they directly integrate calcium... 
Cardiovascular | Repolarization reserve | Action potential | Apamin | SK2 | Intracellular calcium | CARDIAC & CARDIOVASCULAR SYSTEMS | ATRIAL | CA2+-ACTIVATED K+ CHANNELS | HEART-FAILURE | MUSCLE | PROLONGATION | VENTRICULAR MYOCYTES | CELL BIOLOGY | INTRACELLULAR CA2 | CONTRACTION | EXPRESSION | INSIGHTS | Immunohistochemistry | Small-Conductance Calcium-Activated Potassium Channels - physiology | Humans | Rats | Male | Apamin - pharmacology | Rats, Sprague-Dawley | Blotting, Western | Small-Conductance Calcium-Activated Potassium Channels - metabolism | Microscopy, Confocal | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Myocardium - metabolism | Dogs | Heart - drug effects | Myocytes, Cardiac - metabolism | Female | Action Potentials - drug effects
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13. Full Text Weaker contribution of I K1 current to the cardiac repolarization reserve in human versus dog ventricular muscle
by Jost, Norbert and Szűts, Viktoria and Virag, László and Seprényi, György and Szabad, János and Puskás, László and Gy, Julius
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2008, Volume 44, Issue 4, pp. 786 - 786
Cardiovascular pharmacology | Ion currents | Electrophysiology
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14. Full Text Expression alterations of ion channels for IK1 current in dilated cardiomyopathy of human heart
by Szűts, Viktoria and Baczkó, István and Puskás, László G and Bódi, Zoltán and Csincsik, L and Houshmand, N and Jost, Norbert and Virág, László and Papp, Julius Gy and Varró, András
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2008, Volume 44, Issue 4, pp. 811 - 811
Cardiovascular
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15. Full Text Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology
by Szabolcs, Annamária and Tiszlavicz, László and Kaszaki, József and Pósa, Anikó and Berkó, Anikó and Varga, Ilona S and Boros, Imre and Szüts, Viktória and Lonovics, János and Takács, Tamás
Pancreas, ISSN 0885-3177, 10/2007, Volume 35, Issue 3, pp. 249 - 255
Objective: Our experiments were designed to investigate the effects of zerumbone pretreatment on cholecystokinin octapeptide (CCK-8) -induced acute... 
Rat | Zerumbone | Pancreatitis | RESVERATROL | OXIDATIVE STRESS | ACTIVATION | SUPEROXIDE DISMUTASE | rat | GINGER SESQUITERPENE | zerumbone | RAT MODEL | NITRIC-OXIDE | pancreatitis | CANCER-CELL-PROLIFERATION | FREE-RADICAL GENERATION | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | Interleukin-6 - analysis | Amylases - blood | Lipase - blood | Rats, Wistar | Sincalide - toxicity | Male | Pancreatitis - drug therapy | Sesquiterpenes - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Calcium - blood | Nitric Oxide Synthase Type II - analysis | Drug Evaluation, Preclinical | Acute Disease | Superoxide Dismutase - analysis | Rats | Antioxidants - pharmacology | Random Allocation | Pancreatitis - chemically induced | Tumor Necrosis Factor-alpha - analysis | Antioxidants - therapeutic use | Organ Size - drug effects | Animals | Aspartate Aminotransferases - blood | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Pancreatitis - pathology | I-kappa B Proteins - analysis | Pancreatitis - metabolism | Sesquiterpenes - pharmacology
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