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animals (20) 20
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Diabetologia, ISSN 0012-186X, 5/2017, Volume 60, Issue 5, pp. 927 - 937
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2316 - 2327
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 2, pp. 383 - 395
Carcinoma‐associated fibroblasts (CAFs) play a key onco‐supportive role during prostate cancer (PCa) development and progression. We previously reported that... 
cancer‐associated fibroblast | microenvironment | prostate cancer | transforming growth factor beta | reactive oxygen species | in situ hybridization | cancer-associated fibroblast | CELLS | TGF-BETA | CROSS-TALK | LUNG-CANCER | GROWTH-FACTOR-BETA | ONCOLOGY | REACTIVE STROMA | SELENIUM SUPPLEMENTATION | PREDICTS CLINICAL PROGRESSION | CANCER PREVENTION | NADPH OXIDASES | Prostatic Neoplasms - metabolism | NADPH Oxidase 4 - genetics | Reactive Oxygen Species - metabolism | Cancer-Associated Fibroblasts - metabolism | Humans | Stromal Cells - metabolism | Transforming Growth Factor beta1 - metabolism | Cancer-Associated Fibroblasts - drug effects | Culture Media, Conditioned - pharmacology | Male | Cell Movement - drug effects | NADPH Oxidase 4 - metabolism | Prostatic Neoplasms - genetics | Sequence Analysis, RNA | Signal Transduction - drug effects | Cell Line, Tumor | Pyridines - pharmacology | Oxidative Stress - drug effects | Cancer-Associated Fibroblasts - cytology | Prostatic Neoplasms - drug therapy | Stromal Cells - cytology | Pyrazoles - pharmacology | Oxidases | Development and progression | RNA | Transforming growth factors | Prostate cancer | Biotechnology | Reactive oxygen species | Phenotypes | Stroma | Paracrine signalling | Activation | Pharmacology | mRNA | Kinases | Ribonucleic acid--RNA | NAD(P)H oxidase | Proteins | Cell activation | NOX4 protein | Cell lines | Fibroblasts | Attenuation | Inhibition | Conditioning | Prostate | Cell migration | Cancer | Recombinant | Tumor Immunology and Microenvironment
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 12/2011, Volume 19, Issue 23, pp. 6989 - 6999
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 06/2014, Volume 25, Issue 6, pp. 1237 - 1254
Journal Article
Circulation, ISSN 0009-7322, 05/2013, Volume 127, Issue 18, pp. 1888 - +
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2012, Volume 53, Issue 2, pp. 289 - 296
Reactive oxygen species (ROS) play a key role in chronic liver injury and fibrosis. Homologs of NADPH oxidases (NOXs) are major sources of ROS, but the exact... 
NADPH oxidase 4 | Liver fibrosis | Stellate cell activation | Hepatocyte apoptosis | NADPH OXIDASE | ACTIVATION | TGF-BETA | ISOFORMS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | FIBROGENESIS | MECHANISMS | HEPATIC STELLATE CELLS | ENDOCRINOLOGY & METABOLISM | NAD(P)H OXIDASES | STRESS | Liver - pathology | Pyrazoles - therapeutic use | Liver - enzymology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Bile Ducts - metabolism | Humans | NADPH Oxidases - metabolism | Hepatitis, Autoimmune - drug therapy | Hepatocytes - pathology | Smad3 Protein - metabolism | Liver Cirrhosis - enzymology | Hepatic Stellate Cells - cytology | Hepatitis, Autoimmune - pathology | Fas Ligand Protein - pharmacology | Ligation | Liver - drug effects | Gene Deletion | NADPH Oxidases - genetics | NADH, NADPH Oxidoreductases - metabolism | Hepatocytes - drug effects | Hepatic Stellate Cells - drug effects | Pyrazoles - pharmacology | Pyridines - therapeutic use | Liver Cirrhosis - drug therapy | NADH, NADPH Oxidoreductases - genetics | Bile Ducts - drug effects | NADPH Oxidases - antagonists & inhibitors | Rats | Bile Ducts - surgery | NADPH Oxidase 4 | NADPH Oxidase 1 | Reactive Oxygen Species - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Liver Cirrhosis - pathology | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Pyridines - pharmacology | Dactinomycin - pharmacology | Transforming Growth Factor beta - metabolism | Hepatitis, Autoimmune - enzymology | Hepatocytes - enzymology | Oxidases | Phosphates | Niacinamide | Purines | Liver diseases | Analysis | Liver | Fibrosis | Bone morphogenetic proteins | Transforming growth factors | Muscle proteins | Apoptosis | stellate cell activation | liver fibrosis | hepatocyte apoptosis | nicotinamide adenine dinucleotide phosphate reduced oxidase 4
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 06/2014, Volume 20, Issue 17, pp. 2726 - 2740
Journal Article
Journal Article
Clinical Science, ISSN 0143-5221, 02/2013, Volume 124, Issue 3, pp. 191 - 202
Nox (NADPH oxidase)-derived ROS (reactive oxygen species) have been implicated in the development of diabetic nephropathy. Of the Nox isoforms in the kidney,... 
Oxidative stress | Diabetes | NADPH oxidase | NOX inhibitor | Kidney | db/db mouse | KIDNEY-DISEASE | MEDICINE, RESEARCH & EXPERIMENTAL | DB/DB MICE | MECHANISMS | NEPHROPATHY | FAMILY | kidney | INDUCED OXIDATIVE STRESS | NOX4 | COMPLICATIONS | HYPERTENSION | diabetes | oxidative stress | NADPH OXIDASE INHIBITOR | Gene Expression Regulation, Enzymologic - drug effects | Superoxide Dismutase - genetics | Kidney - pathology | Diabetic Nephropathies - etiology | NADPH Oxidases - metabolism | Body Weight - drug effects | Male | Kidney - metabolism | Diabetic Nephropathies - physiopathology | NADPH Oxidases - genetics | Thiobarbituric Acid Reactive Substances - analysis | Blood Pressure - drug effects | Albuminuria - urine | NADH, NADPH Oxidoreductases - metabolism | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Type 2 - complications | Superoxide Dismutase - metabolism | Disease Models, Animal | Pyrazoles - pharmacology | NADH, NADPH Oxidoreductases - genetics | Kidney - drug effects | Blood Glucose - analysis | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Diabetes Mellitus, Type 2 - urine | NADPH Oxidase 4 | Albuminuria - prevention & control | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | NADPH Oxidase 1 | Diabetes Mellitus, Type 2 - blood | Animals | Mice | NADH, NADPH Oxidoreductases - antagonists & inhibitors | Superoxide Dismutase-1 | Vascular Cell Adhesion Molecule-1 - metabolism | Transforming Growth Factor beta - metabolism | Pyridones - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2018, Volume 110, Issue 1, pp. 109 - 120
Background: Cancer-associated fibroblasts (CAFs) are tumor-promoting and correlate with poor survival in many cancers, which has led to their emergence as... 
CELL LUNG-CANCER | PHASE-II TRIAL | OXIDATIVE STRESS | ONCOLOGY | NAB-PACLITAXEL | ACTIVATION PROTEIN | DEPENDENT INVASION | PANCREATIC-CANCER | MONOCLONAL-ANTIBODY | DIFFERENTIATION | STROMAL CELLS | Lung Neoplasms - drug therapy | Up-Regulation | Pyrazoles - therapeutic use | Reactive Oxygen Species - metabolism | Cell Count | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Head and Neck Neoplasms - chemistry | RNA Interference | Cancer-Associated Fibroblasts - chemistry | Aged, 80 and over | NADPH Oxidases - genetics | Adenocarcinoma - chemistry | Esophageal Neoplasms - chemistry | Lung Neoplasms - chemistry | NADPH Oxidases - antagonists & inhibitors | Head and Neck Neoplasms - drug therapy | Carcinoma, Squamous Cell - chemistry | Survival Rate | Adenocarcinoma - drug therapy | Disease Progression | Phenotype | Carcinoma, Squamous Cell - drug therapy | Head and Neck Neoplasms - genetics | Mice | Neoplasm Transplantation | Carcinoma, Non-Small-Cell Lung - chemistry | Carcinoma, Squamous Cell - genetics | Colorectal Neoplasms - chemistry | Cell Transdifferentiation - genetics | Myofibroblasts - chemistry | Actins - analysis | Cell Transdifferentiation - drug effects | Adult | Female | Adenocarcinoma - genetics | Cancer-Associated Fibroblasts - physiology | Pyridines - therapeutic use | Lung Neoplasms - genetics | Myofibroblasts - pathology | Carcinoma, Non-Small-Cell Lung - genetics | NADPH Oxidases - analysis | Mouth Neoplasms - chemistry | NADPH Oxidase 4 | Cancer-Associated Fibroblasts - pathology | Animals | Esophageal Neoplasms - genetics | Mouth Neoplasms - pathology | Oropharyngeal Neoplasms - chemistry | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Colorectal Neoplasms - pathology | Esophageal Neoplasms - drug therapy
Journal Article
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