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Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, pp. e0117021 - e0117021
While targeted therapy brought a new era in the treatment of BRAF mutant melanoma, therapeutic options for non-BRAF mutant cases are still limited. In order to... 
ZOLEDRONIC ACID | CANCER-CELLS | METASTATIC MELANOMA | POTENT INHIBITOR | IN-VITRO | SIGNALING PATHWAYS | N-RAS | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | BISPHOSPHONATE PAMIDRONATE | GENETIC ALTERATIONS | PTEN Phosphohydrolase - genetics | Prenylation - drug effects | Apoptosis - drug effects | Cell Survival | Membrane Proteins - genetics | Humans | Male | Zoledronic Acid | Melanoma - pathology | Mice, SCID | Animals | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Diphosphonates - therapeutic use | Mice | Imidazoles - therapeutic use | Mutation | Biochemistry | Health aspects | Melanoma | Apoptosis | Cell proliferation | Biotechnology | Animal models | Thoracic surgery | Liver | Xenotransplantation | Colorectal cancer | Raf protein | Cytotoxicity | Oncology | Activation | Metastasis | Kinases | Synergism | Cancer therapies | Anticancer properties | Proteins | Cell growth | Surgery | Xenografts | Cell cycle | Zoledronic acid | Inhibition | Spleen | Medical research | Enzymes | Poly(ADP-ribose) polymerase | Pharmacology | Breast cancer | Ribosomal protein S6 | Cisplatin | Pathology | Sensitivity | Acids | Hepatocytes | Cell death | Cell lines | Antitumor activity | Viability | Prostate | Colonization | Cell migration | PTEN protein | Index Medicus
Journal Article
Magyar onkologia, ISSN 0025-0244, 12/2015, Volume 59, Issue 4, pp. 324 - 328
The rapid selection of the efficient anticancer therapy may decrease the unwanted burden to patients and has financial consequences. Tumor models including... 
Index Medicus
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 12/2009, Volume 102, Issue 6, pp. 1265 - 1273
Journal Article
Journal of Neuropathology and Experimental Neurology, ISSN 0022-3069, 11/2011, Volume 70, Issue 11, pp. 979 - 991
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 48, pp. 79503 - 79514
Background: In non-small cell lung cancer (NSCLC) KRAS-mutant status is a negative prognostic and predictive factor. Nitrogen-containing bisphosphonates... 
Human non-small cell lung cancer | Zoledronic acid | Ras inhibitor | Xenograft model | PANCREATIC-CANCER | INDUCE APOPTOSIS | RAS ONCOGENES | CELL BIOLOGY | BREAST-CANCER | GROWTH-FACTOR RECEPTOR | LUNG-CANCER | xenograft model | IN-VITRO | BISPHOSPHONATES | zoledronic acid | human non-small cell lung cancer | TUMOR-GROWTH | ras inhibitor | PROTEIN PRENYLATION | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Neovascularization, Pathologic | Lung Neoplasms - pathology | Male | Vascular Endothelial Growth Factor A - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | A549 Cells | Genetic Predisposition to Disease | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Invasiveness | Carcinoma, Non-Small-Cell Lung - metabolism | Imidazoles - pharmacology | Cisplatin - pharmacology | Mice, SCID | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Phenotype | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice, Inbred BALB C | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Cell Cycle - drug effects | Diphosphonates - pharmacology | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 47 - 47
Journal Article
Journal Article
Investigational New Drugs, ISSN 0167-6997, 8/2016, Volume 34, Issue 4, pp. 416 - 423
Compared to classical chemotherapy, peptide-based drug targeting is a promising therapeutic approach for cancer, which can provide increased selectivity and... 
Colon cancer | GnRH-III | Daunorubicin | Medicine & Public Health | Oncology | In vivo tumor growth inhibition | Pharmacology/Toxicology | Targeted cancer therapy | Short chain fatty acids | LGNRH-III | GONADOTROPIN-RELEASING-HORMONE | DOXORUBICIN | ANTICANCER DRUG | CANCER | ONCOLOGY | CONJUGATE | PHARMACOLOGY & PHARMACY | RECEPTORS | Antibiotics, Antineoplastic - toxicity | Humans | Male | Pyrrolidonecarboxylic Acid - analogs & derivatives | Butyric Acid - chemistry | Pyrrolidonecarboxylic Acid - therapeutic use | Neovascularization, Pathologic - pathology | Butyric Acid - therapeutic use | Daunorubicin - toxicity | Antibiotics, Antineoplastic - chemistry | Liver - drug effects | Gonadotropin-Releasing Hormone - chemistry | Colorectal Neoplasms - drug therapy | Butyric Acid - toxicity | Female | Gonadotropin-Releasing Hormone - therapeutic use | Pyrrolidonecarboxylic Acid - chemistry | Daunorubicin - therapeutic use | Pyrrolidonecarboxylic Acid - toxicity | Daunorubicin - chemistry | HT29 Cells | Xenograft Model Antitumor Assays | Animals | Antibiotics, Antineoplastic - therapeutic use | Tumor Burden - drug effects | Neovascularization, Pathologic - drug therapy | Heart - drug effects | Cell Proliferation - drug effects | Mice | Colorectal Neoplasms - pathology | Gonadotropin-Releasing Hormone - toxicity | Complications and side effects | Dosage and administration | Research | Drug therapy | Studies | Medical research | Pharmacology | Cancer therapies | Colorectal cancer | Index Medicus | Preclinical Studies
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 1/2008, Volume 184, Issue 1, pp. 1 - 7
Tumor-induced anemia often occurs in cancer patients, and is corrected by recombinant human erythropoietins (rHuEPOs). Recent studies indicated that, besides... 
Recombinant human erythropoietin alpha | Tumor-induced angiogenesis | Tumorinduzierte Angio genese | Oncology | Menschliches Plattenepithelkarzinom | Radiation therapy | Radiotherapy | Tumor xenograft model | Strahlentherapie | Medicine & Public Health | Rekombinantes menschliches Erythropoetin alpha | Menschliches Xenotransplantationsmodell | Human squamous cell carcinoma | OXYGENATION | RECEPTOR | HYPOXIA | tumor xenograft model | RADIATION-THERAPY | recombinant human erythropoietin alpha | human squamous cell carcinoma | III ESOPHAGEAL CANCER | tumor-induced angiogenesis | ONCOLOGY | radiation therapy | ENDOTHELIAL-CELLS | GROWTH | HEMOGLOBIN LEVELS | ANEMIA | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Erythropoietin - pharmacology | Neoplasm Transplantation | Tumor Stem Cell Assay | Apoptosis - drug effects | Apoptosis - radiation effects | Carcinoma, Squamous Cell - pathology | Humans | Radiation-Sensitizing Agents - pharmacology | Cell Division - radiation effects | Transplantation, Heterologous | Recombinant Proteins | Carcinoma, Squamous Cell - radiotherapy | Mice, SCID | Cell Division - drug effects | Animals | Soft Tissue Neoplasms - radiotherapy | Soft Tissue Neoplasms - pathology | Cell Line, Tumor | Female | Mice | In Vitro Techniques | Development and progression | Erythropoietin | Growth factors | Radiation | Tumors | Hypoxia | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal Article
Clinical & Experimental Metastasis, ISSN 0262-0898, 4/2013, Volume 30, Issue 4, pp. 497 - 506
Journal Article