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The American Journal of Human Genetics, ISSN 0002-9297, 08/2009, Volume 85, Issue 2, pp. 248 - 253
Journal Article
Dermato-Endocrinology, ISSN 1938-1972, 07/2011, Volume 3, Issue 3, pp. 136 - 140
Vitamin A and its natural and synthetic metabolites (retinoids) affect growth and differentiation of human skin and among the genes affected by retinoids in... 
Keratinocytes | Keratin | Epidermis | Retinoids | Keratin mutations | Retinoic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e29471 - e29471
Keratosis linearis with ichthyosis congenita and keratoderma (KLICK) is an autosomal recessive skin disorder associated with a single-nucleotide deletion in... 
20S PROTEASOME | IN-VITRO | C/EBP-BETA | FILAGGRIN | BIOLOGY | KERATINOCYTES | CHOP | ENDOPLASMIC-RETICULUM STRESS | SKIN | DIFFERENTIATION | HUMAN EPIDERMIS | Epidermis - metabolism | RNA, Small Interfering - genetics | Epidermis - pathology | Protein Biosynthesis | Molecular Chaperones - metabolism | Skin Diseases - genetics | Skin Diseases - metabolism | Unfolded Protein Response - genetics | Humans | Gene Silencing | Molecular Chaperones - genetics | 5' Untranslated Regions - genetics | Skin Diseases - pathology | Endoplasmic Reticulum Stress - genetics | Gene Knockdown Techniques | Cell Differentiation - genetics | Phenotype | HeLa Cells | Mutation | Proteasome Endopeptidase Complex - metabolism | Skin Diseases - congenital | Intermediate Filament Proteins - metabolism | Molecular Chaperones - biosynthesis | Comparative analysis | Skin | Genetic transcription | Haplotypes | Transcription factors | Transcription | Laboratories | Staining | Homology | Filaggrin | CCAAT/enhancer-binding protein | Gene deletion | Proteins | Lysates | Genotype & phenotype | Immunology | Clonal deletion | Protein folding | Deletion | Maturation | Cloning | Keratinocytes | Cultures | siRNA | Ichthyosis | Hereditary diseases | Studies | Pathology | Genodermatosis | Biopsy | Aberration | Differentiation | Endoplasmic reticulum | Cancer | Apoptosis | Keratosis | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Clinical genetics | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | Medicinska och farmaceutiska grundvetenskaper | MEDICINE | Dermatologi och venerologi, klinisk genetik, invärtesmedicin | Klinisk genetik | Dermatology and venerology,clinical genetics, internal medicine
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2008, Volume 128, Issue 5, pp. 1212 - 1219
Detergents are skin irritants affecting keratinocytes. In this study, healthy volunteers were exposed to water (vehicle) and 1% sodium lauryl sulfate (SLS)... 
ATOPIC-DERMATITIS | FILAGGRIN | ENZYMES | EPIDERMIS | ENVELOPE | CALCIUM | KERATINOCYTES | IRRITANT CONTACT-DERMATITIS | DIFFERENTIATION | PERMEABILITY BARRIER | DERMATOLOGY | Skin - metabolism | Humans | Middle Aged | Transglutaminases - genetics | Male | Sodium Dodecyl Sulfate - toxicity | RNA, Messenger - metabolism | Intermediate Filament Proteins - genetics | Adult | Dermatitis, Irritant - pathology | Female | Patch Tests | Skin - pathology | Protein Precursors - genetics | Kallikreins - genetics | Irritants - toxicity | Reverse Transcriptase Polymerase Chain Reaction | Protein Precursors - metabolism | Keratinocytes - pathology | Keratinocytes - drug effects | Biopsy | Cell Differentiation - drug effects | Keratinocytes - metabolism | Transglutaminases - metabolism | Dermatitis, Irritant - physiopathology | Wound Healing - physiology | Skin - physiopathology | Intermediate Filament Proteins - metabolism | Kallikreins - metabolism | Index Medicus | Medical and Health Sciences | Intermediate Filament Proteins/genetics/metabolism | Dermatology and Venereal Diseases | Medicin och hälsovetenskap | Dermatologi och venereologi | Dermatitis; Irritant/pathology/physiopathology | Wound Healing/physiology | Mathematics | Klinisk medicin | MEDICINE | Protein Precursors/genetics/metabolism | Irritants/toxicity | Sodium Dodecyl Sulfate/toxicity | Kallikreins/genetics/metabolism | Natural Sciences | Keratinocytes/drug effects/metabolism/pathology | Dermatologi och venerologi, klinisk genetik, invärtesmedicin | Cell Differentiation/drug effects | Skin/metabolism/pathology/physiopathology | RNA; Messenger/metabolism | Transglutaminases/genetics/metabolism | Dermatology and venerology,clinical genetics, internal medicine | Clinical Medicine | Naturvetenskap | MEDICIN | Dermatologi och venerologi | Matematik | Dermatology and venerology
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2010, Volume 130, Issue 1, pp. 124 - 134
Journal Article
Journal of Dermatological Science, ISSN 0923-1811, 2012, Volume 69, Issue 3, pp. 195 - 201
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 08/2011, Volume 131, Issue 8, pp. 1684 - 1691
Epidermolysis bullosa simplex (EBS) is a blistering skin disease caused by mutations in keratin genes ( or ), with no existing therapies. Aggregates of... 
APOPTOSIS | TRIMETHYLAMINE N-OXIDE | CLINICAL-TRIAL | CYTOSKELETON | MUTANT KERATINS | DOWLING-MEARA | SODIUM 4-PHENYLBUTYRATE | MUTATIONS | CULTURED-CELLS | EXPRESSION | DERMATOLOGY | Proteostasis Deficiencies - metabolism | MAP Kinase Signaling System - physiology | Molecular Chaperones - metabolism | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Hot Temperature - adverse effects | Enzyme Inhibitors - pharmacology | Proteostasis Deficiencies - pathology | Imidazoles - pharmacology | Heat-Shock Response - physiology | HSP70 Heat-Shock Proteins - metabolism | Cell Division - physiology | Leupeptins - pharmacology | Keratinocytes - pathology | Epidermolysis Bullosa Simplex - pathology | MAP Kinase Signaling System - drug effects | Keratinocytes - metabolism | Cysteine Proteinase Inhibitors | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | HSP90 Heat-Shock Proteins - metabolism | Keratin-5 - metabolism | Pyridines - pharmacology | Proteasome Endopeptidase Complex - metabolism | Epidermolysis Bullosa Simplex - metabolism | Proteasome Inhibitors | Cell Line, Transformed | Index Medicus | Clinical Medicine | Medical and Health Sciences | Dermatology and Venereal Diseases | Medicin och hälsovetenskap | Dermatologi och venereologi | MEDICIN | Klinisk medicin | MEDICINE
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2011, Volume 6, Issue 12, pp. e28254 - e28254
Background: Several common genetic and environmental disease mechanisms are important for the pathophysiology behind atopic dermatitis (AD). Filaggrin (FLG)... 
GENE | ECZEMA | PATHOGENIC MECHANISMS | CALCIUM | BIOLOGY | BARRIER FUNCTION | VALIDATION | KERATINOCYTES | MUTATIONS | DIFFERENTIATION | EXPRESSION | Dermatitis, Atopic - genetics | Multigene Family | Oligonucleotide Array Sequence Analysis | Signal Transduction | Humans | Middle Aged | Gene Expression Regulation | Genotype | Lipid Metabolism | Male | Dermatitis, Atopic - pathology | Inflammation | Ichthyosis Vulgaris - genetics | RNA, Messenger - metabolism | Cell Adhesion | Ichthyosis Vulgaris - pathology | Intermediate Filament Proteins - genetics | Adult | Female | Surveys and Questionnaires | Aged | Cell Differentiation | Skin - pathology | Hydrogen-Ion Concentration | Advertising executives | RNA | Atopic dermatitis | Analysis | Genes | Skin | Genetic aspects | Gene expression | Ichthyosis | Pathogenesis | Homeostasis | Filaggrin | Family medical history | pH effects | Dermatitis | Genotype & phenotype | Keratin | Signal transduction | Alterations | Water loss | Pathways | Surgery | Lipid metabolism | Localization | Immunoglobulins | Congenital diseases | Dermatology | Metabolism | Patients | Allergies | Medicine | Signaling | Hospitals | DNA microarrays | Genotyping | Biopsy | Mutation | Differentiation | Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Dermatology and Venereal Diseases | Medicin och hälsovetenskap | Dermatologi och venereologi | pH
Journal Article
Dermato-Endocrinology, ISSN 1938-1972, 07/2011, Volume 3, Issue 3, pp. 136 - 140
Vitamin A and its natural and synthetic metabolites (retinoids) affect growth and differentiation of human skin and among the genes affected by retinoids in... 
Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | retinoic acid | keratin | keratin mutations | Review | keratinocytes | retinoids | epidermis | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Dermatology and Venereal Diseases | Medicin och hälsovetenskap | Dermatologi och venereologi
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2010, Volume 86, Issue 4, pp. 596 - 603
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/1998, Volume 253, Issue 1, pp. 192 - 192
Journal Article
Journal Article
Stem Cell Research, ISSN 1873-5061, 05/2019, Volume 37, pp. 101424 - 101424
We have generated MLi002-A, a new induced pluripotent stem cell (iPSC) line derived from keratinocytes of a skin punch biopsy of a female patient with the... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Research | Epidermolysis bullosa | Gene mutations | Stem cells
Journal Article
Experimental Dermatology, ISSN 0906-6705, 02/2018, Volume 27, Issue 2, pp. 196 - 199
Journal Article
Archives of Dermatological Research, ISSN 0340-3696, 9/2017, Volume 309, Issue 7, pp. 587 - 593
The keratin filament cytoskeleton is vital to the normal function of epithelial cells. It provides structural support and regulates different aspects of cell... 
Keratin | Medicine & Public Health | Dermatology | DNA damage | Keratinocyte | Mutation | Chk2 | Apoptosis |