Chirality, ISSN 0899-0042, 08/2011, Volume 23, Issue 7, pp. 557 - 567
To evaluate the biological preference of chiral drug candidates for molecular target DNA, new potential metal‐based chemotherapeutic agents 1, 1a, 1b, 2, 2a,...
in vitro DNA‐binding studies | circular dichroism cleavage efficiency | chiral discrimination | topoisomerase II inhibitor | in vitro DNA-binding studies | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | CALF-THYMUS DNA | CRYSTAL-STRUCTURE | X-RAY-STRUCTURE | CHEMISTRY, ORGANIC | DOUBLE-STRANDED DNA | CLEAVAGE | ANTICANCER ACTIVITY | CHEMISTRY | PHARMACOLOGY & PHARMACY | VITRO ANTITUMOR-ACTIVITY | MAGNETIC-PROPERTIES | SCHIFF-BASE LIGANDS | DNA Topoisomerases, Type II - metabolism | Reproducibility of Results | Stereoisomerism | Humans | Substrate Specificity | DNA - metabolism | Topoisomerase II Inhibitors - metabolism | Benzyl Compounds - chemistry | Absorption | Animals | Copper - chemistry | Organometallic Compounds - metabolism | Topoisomerase II Inhibitors - chemistry | Cattle | Organometallic Compounds - chemical synthesis | Electrochemistry | Organometallic Compounds - chemistry | Topoisomerase II Inhibitors - chemical synthesis | Spectrum Analysis | Human | Transition metals | Inhibitors | Deoxyribonucleic acid | Chirality | Cleavage | TITRATION | COPPER COMPOUNDS | Three dimensional | Index Medicus
in vitro DNA‐binding studies | circular dichroism cleavage efficiency | chiral discrimination | topoisomerase II inhibitor | in vitro DNA-binding studies | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | CALF-THYMUS DNA | CRYSTAL-STRUCTURE | X-RAY-STRUCTURE | CHEMISTRY, ORGANIC | DOUBLE-STRANDED DNA | CLEAVAGE | ANTICANCER ACTIVITY | CHEMISTRY | PHARMACOLOGY & PHARMACY | VITRO ANTITUMOR-ACTIVITY | MAGNETIC-PROPERTIES | SCHIFF-BASE LIGANDS | DNA Topoisomerases, Type II - metabolism | Reproducibility of Results | Stereoisomerism | Humans | Substrate Specificity | DNA - metabolism | Topoisomerase II Inhibitors - metabolism | Benzyl Compounds - chemistry | Absorption | Animals | Copper - chemistry | Organometallic Compounds - metabolism | Topoisomerase II Inhibitors - chemistry | Cattle | Organometallic Compounds - chemical synthesis | Electrochemistry | Organometallic Compounds - chemistry | Topoisomerase II Inhibitors - chemical synthesis | Spectrum Analysis | Human | Transition metals | Inhibitors | Deoxyribonucleic acid | Chirality | Cleavage | TITRATION | COPPER COMPOUNDS | Three dimensional | Index Medicus
Journal Article
RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 11, pp. 6587 - 6597
Chiral pseudopeptide Cu(II) and Zn(II) complexes (1(S/R) and 2(S/R), respectively), were obtained by a de novo synthetic strategy employing pseudopeptide...
COPPER(II) COMPLEXES | CELLS | ANTICANCER | CRYSTAL-STRUCTURE | LIGAND | SPECTRAL CHARACTERIZATION | CYTOTOXIC ACTIVITY | BINDING | CANCER | CHEMISTRY, MULTIDISCIPLINARY | ZINC(II) COMPLEXES
COPPER(II) COMPLEXES | CELLS | ANTICANCER | CRYSTAL-STRUCTURE | LIGAND | SPECTRAL CHARACTERIZATION | CYTOTOXIC ACTIVITY | BINDING | CANCER | CHEMISTRY, MULTIDISCIPLINARY | ZINC(II) COMPLEXES
Journal Article
Journal of the American College of Radiology, ISSN 1546-1440, 11/2017, Volume 14, Issue 11, p. S406-S420
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jacr.2017.08.035 Byline: Bruno Policeni (a), Amanda S. Corey (b),...
Decision-making
Decision-making
Journal Article
Dalton Transactions, ISSN 1477-9226, 03/2013, Volume 42, Issue 10, pp. 3390 - 3401
New dimethyltin derived antitumor drug candidates (S)- and (R)-[4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(IV), 1 and (S)- and...
COPPER(II) COMPLEXES | DNA-BINDING | ORGANOTIN(IV) COMPLEXES | MOLECULAR-STRUCTURE | CRYSTAL-STRUCTURE | AMINO-ACIDS | X-RAY STRUCTURES | SCHIFF-BASE LIGANDS | DIORGANOTIN(IV) COMPLEXES | SOLID-STATE | CHEMISTRY, INORGANIC & NUCLEAR | Lung Neoplasms - drug therapy | Tin Compounds - toxicity | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Organotin Compounds - toxicity | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - toxicity | Organotin Compounds - chemical synthesis | Tin Compounds - therapeutic use | Osmolar Concentration | MCF-7 Cells | Drug Design | Coordination Complexes - toxicity | Cell Survival - drug effects | DNA - metabolism | DNA Cleavage - drug effects | Coordination Complexes - therapeutic use | DNA - chemistry | Tin Compounds - chemical synthesis | Animals | Mice, Nude | Schiff Bases - chemistry | K562 Cells | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Mice | Kinetics | Drug Screening Assays, Antitumor | Organotin Compounds - therapeutic use
COPPER(II) COMPLEXES | DNA-BINDING | ORGANOTIN(IV) COMPLEXES | MOLECULAR-STRUCTURE | CRYSTAL-STRUCTURE | AMINO-ACIDS | X-RAY STRUCTURES | SCHIFF-BASE LIGANDS | DIORGANOTIN(IV) COMPLEXES | SOLID-STATE | CHEMISTRY, INORGANIC & NUCLEAR | Lung Neoplasms - drug therapy | Tin Compounds - toxicity | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Organotin Compounds - toxicity | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - toxicity | Organotin Compounds - chemical synthesis | Tin Compounds - therapeutic use | Osmolar Concentration | MCF-7 Cells | Drug Design | Coordination Complexes - toxicity | Cell Survival - drug effects | DNA - metabolism | DNA Cleavage - drug effects | Coordination Complexes - therapeutic use | DNA - chemistry | Tin Compounds - chemical synthesis | Animals | Mice, Nude | Schiff Bases - chemistry | K562 Cells | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Mice | Kinetics | Drug Screening Assays, Antitumor | Organotin Compounds - therapeutic use
Journal Article
Journal of the American College of Radiology, ISSN 1546-1440, 11/2017, Volume 14, Issue 11
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jacr.2017.08.038 Byline: Jason W. Schroeder (a), Thomas Ptak (b),...
Decision-making | CT imaging
Decision-making | CT imaging
Journal Article
Journal of the American College of Radiology, ISSN 1546-1440, 05/2017, Volume 14, Issue 5, p. S34-S61
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jacr.2017.01.051 Byline: Michael B. Salmela (a), Shabnam Mortazavi...
Stroke (Disease) | Decision-making
Stroke (Disease) | Decision-making
Journal Article
Journal of the American College of Radiology, ISSN 1546-1440, 2017, Volume 14, Issue 5, pp. S34 - S61
Abstract Diseases of the cerebral vasculature represent a heterogeneous group of ischemic and hemorrhagic etiologies, which often manifest clinically as an...
Radiology | arteriovenous malformation | cerebrovascular disease | vasculitis | cerebral aneurysm | Appropriate Use Criteria | transient ischemic attack | stroke | Appropriateness Criteria | AUC | CAROTID-ARTERY STENOSIS | ANEURYSMAL SUBARACHNOID HEMORRHAGE | strike | DURAL ARTERIOVENOUS-FISTULAS | DIGITAL-SUBTRACTION-ANGIOGRAPHY | COMPUTED TOMOGRAPHIC ANGIOGRAPHY | ACUTE ISCHEMIC-STROKE | CENTRAL-NERVOUS-SYSTEM | RUPTURED INTRACRANIAL ANEURYSMS | TRANSCRANIAL DOPPLER SONOGRAPHY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | DEVELOPMENTAL VENOUS ANOMALIES | Stroke - diagnostic imaging | United States | Humans | Brain Ischemia - etiology | Cerebral Hemorrhage - diagnostic imaging | Diagnostic Imaging - methods | Magnetic Resonance Imaging | Stroke - etiology | Societies, Medical | Cerebrovascular Disorders - complications | Cerebrovascular Disorders - diagnostic imaging | Cerebral Hemorrhage - complications | Brain Ischemia - diagnostic imaging
Radiology | arteriovenous malformation | cerebrovascular disease | vasculitis | cerebral aneurysm | Appropriate Use Criteria | transient ischemic attack | stroke | Appropriateness Criteria | AUC | CAROTID-ARTERY STENOSIS | ANEURYSMAL SUBARACHNOID HEMORRHAGE | strike | DURAL ARTERIOVENOUS-FISTULAS | DIGITAL-SUBTRACTION-ANGIOGRAPHY | COMPUTED TOMOGRAPHIC ANGIOGRAPHY | ACUTE ISCHEMIC-STROKE | CENTRAL-NERVOUS-SYSTEM | RUPTURED INTRACRANIAL ANEURYSMS | TRANSCRANIAL DOPPLER SONOGRAPHY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | DEVELOPMENTAL VENOUS ANOMALIES | Stroke - diagnostic imaging | United States | Humans | Brain Ischemia - etiology | Cerebral Hemorrhage - diagnostic imaging | Diagnostic Imaging - methods | Magnetic Resonance Imaging | Stroke - etiology | Societies, Medical | Cerebrovascular Disorders - complications | Cerebrovascular Disorders - diagnostic imaging | Cerebral Hemorrhage - complications | Brain Ischemia - diagnostic imaging
Journal Article
International Journal of Phytoremediation, ISSN 1522-6514, 2018, Volume 21, Issue 2, pp. 160 - 169
In a first-ever report on this subject, it is shown that a common amphibious plant joyweed (Alternanthera sessilis) can be used in rapid and efficient...
bioremediation | domestic sewage treatment | SHEFROL | Alternanthera sessilis | WASTE-WATER TREATMENT | ENERGY | MACROPHYTES | SHEFROL (R) | COLOMBO DISTRICT | NITROGEN REMOVAL | SANITATION | ENVIRONMENTAL SCIENCES | CONSTRUCTED WETLANDS | HEAVY-METAL | GREY WATER | PATHOGENS | Biodegradation | Patents | Waste treatment | Biodegradability | Sewage treatment | Fecal coliforms | Hydraulic retention time | Retention time | Wastewater treatment | Heavy metals | Organic chemistry | Sewage disposal | Sewage | Laminar flow | Chemical oxygen demand | Bioreactors | Tertiary treatment | Suspended solids | Domestic wastes | Solid suspensions | Biochemical oxygen demand
bioremediation | domestic sewage treatment | SHEFROL | Alternanthera sessilis | WASTE-WATER TREATMENT | ENERGY | MACROPHYTES | SHEFROL (R) | COLOMBO DISTRICT | NITROGEN REMOVAL | SANITATION | ENVIRONMENTAL SCIENCES | CONSTRUCTED WETLANDS | HEAVY-METAL | GREY WATER | PATHOGENS | Biodegradation | Patents | Waste treatment | Biodegradability | Sewage treatment | Fecal coliforms | Hydraulic retention time | Retention time | Wastewater treatment | Heavy metals | Organic chemistry | Sewage disposal | Sewage | Laminar flow | Chemical oxygen demand | Bioreactors | Tertiary treatment | Suspended solids | Domestic wastes | Solid suspensions | Biochemical oxygen demand
Journal Article
9.
STUDY OF ORAL HYPOGLYCEMIC ACTIVITY OF RHIZOMES OF HEMIDESMUS INDICUS R. Br. IN ALBINO WISTAR RATS
International Journal of Pharmaceutical Sciences and Drug Research, 11/2016, Volume 7, Issue 11, pp. 4602 - 4602
The present study was carried out to evaluate oral hypoglycemic activity of rhizome of Hemidesmus indicus R.Br. in Albino wistar rats. Hemidesmus indicus...
Journal Article
AJIC: American Journal of Infection Control, ISSN 0196-6553, 2016, Volume 44, Issue 12, pp. 1495 - 1504
Highlights • We report INICC device-associated module data of 50 countries from 2010-2015. • We collected prospective data from 861,284 patients in 703 ICUs...
Infectious Disease | Infection Control | Limited resources countries | Health care-associated infection | Ventilator-associated pneumonia | Urinary tract infection | Bloodstream infection | Catheter-associated urinary tract infection | Antibiotic resistance | Hospital infection | Developing countries | Central line-associated bloodstream infections | SOCIOECONOMIC IMPACT | INFECTIOUS DISEASES | INTENSIVE-CARE UNITS | PREVENTION | CONTROL STRATEGY | MULTIDIMENSIONAL APPROACH | LIMITED-RESOURCE COUNTRIES | RATES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INICC REPORT | SAFETY NETWORK | Intensive Care Units | Prospective Studies | Cross Infection - etiology | Global Health | Humans | Middle Aged | Child, Preschool | Infant | Male | Incidence | Young Adult | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Infant, Newborn | Cross Infection - epidemiology | Drug resistance | Health aspects | Infection control
Infectious Disease | Infection Control | Limited resources countries | Health care-associated infection | Ventilator-associated pneumonia | Urinary tract infection | Bloodstream infection | Catheter-associated urinary tract infection | Antibiotic resistance | Hospital infection | Developing countries | Central line-associated bloodstream infections | SOCIOECONOMIC IMPACT | INFECTIOUS DISEASES | INTENSIVE-CARE UNITS | PREVENTION | CONTROL STRATEGY | MULTIDIMENSIONAL APPROACH | LIMITED-RESOURCE COUNTRIES | RATES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INICC REPORT | SAFETY NETWORK | Intensive Care Units | Prospective Studies | Cross Infection - etiology | Global Health | Humans | Middle Aged | Child, Preschool | Infant | Male | Incidence | Young Adult | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Infant, Newborn | Cross Infection - epidemiology | Drug resistance | Health aspects | Infection control
Journal Article
Turkish Journal of Biochemistry, ISSN 0250-4685, 05/2018, Volume 43, Issue 4, pp. 447 - 455
Background: Ocimum basilicum, Thymus vulgaris, and Rosmarinus officinalis have been used for the treatment of different ailments for a historically long time...
Flavonoids | Toxicity assay | Phytoconstituents | Antioxidant activity | Toksisite testi | Flavonoidler | Antioksidan aktivite | Total phenolic | Fitoconstituentler | Hayvan etüdü | Toplam fenolik | Animal study | WISTAR RATS | ESSENTIAL OILS | SAFETY | BIOCHEMISTRY & MOLECULAR BIOLOGY | THYMUS-VULGARIS | ROSEMARY | ANTIOXIDANT | CHEMICAL-COMPOSITION | ANTIMICROBIAL ACTIVITY | EXTRACT
Flavonoids | Toxicity assay | Phytoconstituents | Antioxidant activity | Toksisite testi | Flavonoidler | Antioksidan aktivite | Total phenolic | Fitoconstituentler | Hayvan etüdü | Toplam fenolik | Animal study | WISTAR RATS | ESSENTIAL OILS | SAFETY | BIOCHEMISTRY & MOLECULAR BIOLOGY | THYMUS-VULGARIS | ROSEMARY | ANTIOXIDANT | CHEMICAL-COMPOSITION | ANTIMICROBIAL ACTIVITY | EXTRACT
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 44, pp. 18961 - 18966
It is being realized that identification of subgroups within normal controls corresponding to contrasting disease susceptibility is likely to lead to more...
High altitude | Gene frequency | Genetic variation | Alleles | Medical genetics | Pulmonary edema | Population genetics | Genotypes | Human genetics | Altitude | Hypoxia | Phenotype | High-altitude pulmonary edema | Prakriti | Indian genome variation database | phenotype | Indian Genome Variation Database | hypoxia | high-altitude pulmonary edema | MULTIDISCIPLINARY SCIENCES | Medicine, Ayurvedic | Pulmonary Edema - genetics | Humans | Male | Hypoxia-Inducible Factor-Proline Dioxygenases | India | Polymorphism, Genetic | Procollagen-Proline Dioxygenase - genetics | Adaptation, Physiological - genetics |
High altitude | Gene frequency | Genetic variation | Alleles | Medical genetics | Pulmonary edema | Population genetics | Genotypes | Human genetics | Altitude | Hypoxia | Phenotype | High-altitude pulmonary edema | Prakriti | Indian genome variation database | phenotype | Indian Genome Variation Database | hypoxia | high-altitude pulmonary edema | MULTIDISCIPLINARY SCIENCES | Medicine, Ayurvedic | Pulmonary Edema - genetics | Humans | Male | Hypoxia-Inducible Factor-Proline Dioxygenases | India | Polymorphism, Genetic | Procollagen-Proline Dioxygenase - genetics | Adaptation, Physiological - genetics |