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Web Resource
2011, Cytokines : intercellular mediators regulating host defense
Web Resource
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2007, Volume 104, Issue 29, pp. 12099 - 12104
CD4⁺ T cells producing IL-17 [T helper (Th)17], as distinct from Th1 or Th2 cells, have recently been shown to be associated with autoimmunity, but it is not... 
T lymphocytes | Cytometry | Receptors | Cytokines | Dendritic cells | Antibodies | Cultured cells | Cell differentiation | Cellular differentiation | Endothelial cells | Regulatory T cells | STAT | TGF-β retinoid-related orphan receptor | GAMMA | AUTOIMMUNE INFLAMMATION | MULTIDISCIPLINARY SCIENCES | INDUCTION | retinoid-related orphan receptor gamma t | regulatory T cells | TGF-beta | TRANSCRIPTION FACTOR FOXP3 | DIRECTS | GENERATION | INFECTION | DIFFERENTIATION | LINEAGE | Interleukin-1beta - pharmacology | Humans | RNA, Messenger - metabolism | Cell Lineage - drug effects | Receptors, Retinoic Acid - genetics | T-Lymphocytes, Helper-Inducer - drug effects | STAT1 Transcription Factor - metabolism | Receptors, Thyroid Hormone - genetics | T-Lymphocytes, Helper-Inducer - cytology | Dendritic Cells - drug effects | Female | STAT3 Transcription Factor - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 | Mice, Inbred C57BL | RNA, Messenger - genetics | Receptors, Retinoic Acid - metabolism | Interleukin-17 - biosynthesis | Gene Expression Regulation - drug effects | Receptors, Thyroid Hormone - metabolism | Transforming Growth Factor beta - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Interleukin-6 - pharmacology | Cell Differentiation - drug effects | Dendritic Cells - cytology | Mice | Interferon-gamma - pharmacology | Physiological aspects | Evaluation | Chemical properties | CD4 lymphocytes | Interleukin-6 | Signal transduction | Immunology | Rodents | Cells | Immune system | Index Medicus | Biological Sciences | TGF-β | retinoid-related orphan receptor γt
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 09/2007, Volume 66, Issue 9, pp. 1162 - 1167
Journal Article
Lancet, The, ISSN 0140-6736, 2008, Volume 371, Issue 9617, pp. 998 - 1006
Journal Article
Modern Rheumatology, ISSN 1439-7595, 2/2009, Volume 19, Issue 1, pp. 12 - 19
Journal Article
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2018, Volume 24, Issue 16, pp. 1766 - 1771
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 46, pp. 19961 - 19966
Although an immunoregulatory role of aryl hydrocarbon receptor (Ahr) has been demonstrated in T cells and macrophages, little is known about its function in... 
T lymphocytes | Dendritic cells | Cytokines | Coculture techniques | Antigen presenting cells | Ligands | Mice | Aryl hydrocarbon receptors | Macrophages | Cellular differentiation | Immune regulation | Dioxin receptor | Tryptophan catabolism | DIOXIN | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | PROLIFERATION | immune regulation | CUTTING EDGE | 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN | dioxin receptor | IDO | AH-RECEPTOR | tryptophan catabolism | EXPRESSION | T-CELLS | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Receptors, Aryl Hydrocarbon - deficiency | Bone Marrow Cells - cytology | Dendritic Cells - immunology | Mice, Inbred C57BL | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Regulatory - drug effects | Th17 Cells - drug effects | Animals | Dendritic Cells - enzymology | Lipopolysaccharides - pharmacology | T-Lymphocytes, Regulatory - cytology | Receptors, Aryl Hydrocarbon - metabolism | Th17 Cells - immunology | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Interleukin-10 - biosynthesis | Th17 Cells - cytology | Cell Proliferation - drug effects | Kynurenine - metabolism | Oligodeoxyribonucleotides - pharmacology | Bone Marrow Cells - metabolism | Cell receptors | Cellular control mechanisms | Genetic aspects | Research | Properties | Human immunogenetics | Proteins | Immunology | Metabolites | Gene expression | Lymphocytes | Index Medicus | Biological Sciences
Journal Article
1992, Chemical immunology, ISBN 9783805554404, Volume 51., ix, 330
Book
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 38, pp. 10625 - 10630
Immunomodulatory drugs (IMiDs) are a family of compounds derived from thalidomide. Binding of the IMiD molecule to the Lon protease Cereblon initiates the... 
Interferon | TLR | Cereblon | STAT1 | IMiD | IMMUNITY | TOLL-LIKE-RECEPTOR-4 | COMPLEX | IKAROS | MULTIDISCIPLINARY SCIENCES | LUPUS-ERYTHEMATOSUS | THALIDOMIDE | interferon | DEGRADATION | EXPRESSION | T-CELLS | E3 UBIQUITIN LIGASE | Toll-like receptors | Observations | Health aspects | Drug interactions | Homeostasis | Molecules | Mutation | Cytokines | Proteases | Binding sites | Index Medicus | Biological Sciences
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, pp. 242 - 242
Journal Article
Cytokine, ISSN 1043-4666, 09/2013, Volume 63, Issue 3, p. 242
Deregulated expression of IL-6 is responsible for several chronic inflammations and hemopoietic malignancies. Humanized antibody against 80kd IL-6R... 
Autoimmunity | RNA | Protein binding
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 46, pp. 11802 - 11807
Journal Article
Immunity, ISSN 1074-7613, 04/2016, Volume 44, Issue 4, pp. 720 - 722
IL-6-STAT3 axis is known as a key factor of tumor progression. In this issue of , Yu and colleagues (2016) show that IL-6-binding CD5, rather than IL-6... 
Signal Transduction - immunology | Phosphorylation | B-Lymphocytes - immunology | Humans | Receptors, Interleukin-6 | STAT3 Transcription Factor - metabolism | Interleukin-6 | B cells | Lymphocyte receptors | Angiogenesis | Lymphocytes | Rodents | Leukemia | Medical prognosis | Multiple myeloma | Physiology | Gene expression | Tumors | Ovarian cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 6, pp. E1214 - E1220
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 23, pp. 9409 - 9414
Posttranscriptional regulation of IL-6 has been largely uncharacterized, with the exception of the ribonuclease Regnase-1, which prevents autoimmunity by... 
Untranslated regions | T lymphocytes | RNA stability | Messenger RNA | Cytokines | HEK293 cells | Peritoneal macrophages | Gene expression regulation | Macrophages | Autoimmune diseases | Rna-protein complex | Immune regulation | RNA-protein complex | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | STABILIZATION | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | BINDING PROTEIN | immune regulation | IL-6-DEFICIENT MICE | ARYL-HYDROCARBON RECEPTOR | AU-RICH ELEMENTS | INFLAMMATORY CYTOKINES | CELL | INTERLEUKIN-6 GENE-EXPRESSION | RNA Stability - immunology | Tumor Necrosis Factor-alpha - metabolism | DNA-Binding Proteins - immunology | Enzyme-Linked Immunosorbent Assay | Mice, Inbred C57BL | RNA-Binding Proteins - immunology | 3' Untranslated Regions - genetics | Encephalomyelitis, Autoimmune, Experimental - immunology | Reverse Transcriptase Polymerase Chain Reaction | Lipopolysaccharides | DNA-Binding Proteins - metabolism | Ribonucleases - antagonists & inhibitors | Transcription Factors - metabolism | Macrophages - metabolism | Animals | Transfection | Interleukin-6 - blood | Luciferases | Interleukin-6 - immunology | Mice | Cell Culture Techniques | Transcription Factors - immunology | RNA-Binding Proteins - metabolism | Autoimmunity | Genetic aspects | Properties | Interleukin-6 | Enzymes | Abandoned mines | Rodents | Cells | Transfer RNA | Immune system | Index Medicus | Biological Sciences
Journal Article