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Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 5080 - 5080
Abstract BACKGROUND: Elderly patients with Relapsed/Refractory (R/R) aggressive Large B-cell lymphoma (LBCL) and Peripheral T-cell lymphomas (PTCL), are... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 5216 - 5216
Abstract Calreticulin (CALR) mutations disrupting domains of the protein that regulate its intracellular trafficking were discovered in patients with... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 767 - 767
Abstract Introduction Effective therapies for R/R AML remain limited. MEK or MDM2 inhibition can downregulate MCL1, overcoming resistance to BCL2 inhibition.... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5550 - 5550
Abstract Introduction. Elderly patients with chronic lymphocytic leukemia (CLL) are often treated with chemoimmunotherapeutic regimens. Because of... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5465 - 5465
Abstract Background Deferasirox (DFX) is an oral iron chelator widely employed in the treatment of iron overload during thalassemic syndromes and... 
Journal Article
Experimental Hematology, ISSN 0301-472X, 2015, Volume 43, Issue 11, pp. 974 - 985.e1
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 4222 - 4222
Abstract Acute myeloid leukemia (AML) has been characterized by a growing number of recurrent genetic alterations, frequently causing the constitutive... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 5045 - 5045
Abstract Glycolysis is the central axis of cellular metabolism. The cancer cell bioenergetic status heavily relies on high glycolytic rates, even in aerobic... 
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 09/2019, Volume 25, Issue 17, pp. 5231 - 5241
Purpose: This study was aimed at evaluating the feasibility, safety, immunologic and clinical responses in patients with follicular lymphoma treated with... 
ONCOLOGY | VACCINATION
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 30, pp. 49451 - 49469
Journal Article
Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 31, pp. 21758 - 21769
Chronic Myeloid Leukemia (CML) is a stem cell disease sustained by a rare population of quiescent cells which are to some extent resistant to tyrosine kinase... 
Proteomic profile | Chronic myeloid leukemia | Cell signaling | Apoptosis | CD34+ cells
Journal Article
BLOOD, ISSN 0006-4971, 09/2019, Volume 132, Issue 12, pp. 935 - 945
We designed a trial in which postremission therapy of young patients with de novo acute myeloid leukemia (AML) was decided combining cytogenetics/genetics and... 
AML | POSTREMISSION THERAPY | MANAGEMENT | HEMATOPOIETIC-CELL TRANSPLANTATION | STANDARD-RISK | RECOMMENDATIONS | CLASSIFICATION | PROGNOSTIC RELEVANCE | HEMATOLOGY | MINIMAL RESIDUAL DISEASE | STRATIFICATION
Journal Article
ONCOTARGET, ISSN 1949-2553, 10/2015, Volume 6, Issue 31, pp. 32089 - 32103
Several chemo-resistance mechanisms including the Bcl-2 protein family overexpression and constitutive activation of the PI3K/Akt/mTOR signaling have been... 
MAMMALIAN TARGET | targeted therapies | FAMILY-MEMBERS | MCL-1 PHOSPHORYLATION | ACUTE MYELOID-LEUKEMIA | BH3 mimetic resistance | ANTIAPOPTOTIC BCL-2 | CELL BIOLOGY | mTOR inhibition | CELL LUNG-CANCER | Mcl-1 | acute lymphoblastic leukemia | ABT-737-INDUCED APOPTOSIS | IN-VIVO | CHRONIC LYMPHOCYTIC-LEUKEMIA | DEPENDENT MECHANISM | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Male | Peptide Fragments - pharmacology | Mechanistic Target of Rapamycin Complex 1 | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Biomimetics | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Adult | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Child | Proto-Oncogene Proteins - pharmacology | Sirolimus - analogs & derivatives | Sulfonamides - pharmacology | Piperazines - pharmacology | Sirolimus - pharmacology | Blotting, Western | Drug Synergism | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Cell Cycle - drug effects | Drug Resistance, Neoplasm - drug effects
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5469 - 5469
Abstract To evaluate the prognosis of patients with Essential Thrombocythemia (ET) in the first decade of the century we assessed retrospectively the... 
Journal Article
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