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1. Full Text Nucleobase synthesis in interstellar ices
by Oba, Yasuhiro and Takano, Yoshinori and Naraoka, Hiroshi and Watanabe, Naoki and Kouchi, Akira
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 8
The synthesis of nucleobases in natural environments, especially in interstellar molecular clouds, is the focus of a long-standing debate regarding prebiotic... 
Clouds | Molecular clouds | Thymine | Adenine | Chemical reactions | Stellar evolution | Photons | Ice | Xanthine | Organic chemistry | Ammonia | Photolysis | Star formation | Interstellar chemistry | Planetary evolution | Hypoxanthine | Cytosine | Astrochemistry | Chemical evolution | Star & galaxy formation | Uracil | Interstellar matter
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2. Full Text Epidemiologic features of 348 children with hepatitis C virus infection over a 30-year period: a nationwide survey in Japan
by Mizuochi, Tatsuki and Takano, Tomoko and Yanagi, Tadahiro and Ushijima, Kosuke and Suzuki, Mitsuyoshi and Miyoshi, Yoko and Ito, Yoshinori and Inui, Ayano and Tajiri, Hitoshi
Journal of Gastroenterology, ISSN 0944-1174, 3/2018, Volume 53, Issue 3, pp. 419 - 426
Although the epidemiology of hepatitis C virus (HCV) infection among children may be rapidly changing, few reports have characterized large nationwide cohorts... 
Liver histopathology | Cirrhosis | Medicine & Public Health | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | Genotype | Surgical Oncology | Maternal transmission | Natural history | FIBROSIS | PREVALENCE | PATHOLOGY | LIVER-DISEASE | GENOTYPES | NON-A | TRANSMISSION | HCV | GLOBAL EPIDEMIOLOGY | GASTROENTEROLOGY & HEPATOLOGY | PROGRESSION | Surveys | Virus diseases | Medical research | Liver | Medicine, Experimental | Interferon | Children | Biological response modifiers | Hepatitis C virus | Liver cirrhosis | Epidemiology | Histochemistry | Hepatocellular carcinoma | Infections | Ribavirin | Liver cancer | Hepatitis | Histopathology | Fibrosis | Hepatitis C | Genotypes
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3. Full Text Guidelines for the use and interpretation of assays for monitoring autophagy
by Klionsky, Daniel J and Abdalla, Fabio C and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi K and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Ann, David K and Anoopkumar-Dukie, Shailendra and Aoki, Hiroshi and Apostolova, Nadezda and Arancia, Giuseppe and Aris, John P and Asanuma, Katsuhiko and Asare, Nana Y.O and Ashida, Hisashi and Askanas, Valerie and Askew, David S and Auberger, Patrick and Baba, Misuzu and Backues, Steven K and Baehrecke, Eric H and Bahr, Ben A and Bai, Xue-Yuan and Bailly, Yannick and Baiocchi, Robert and Baldini, Giulia and Balduini, Walter and Ballabio, Andrea and Bamber, Bruce A and Bampton, Edward T.W and Juhász, Gábor and Bartholomew, Clinton R and Bassham, Diane C and Bast, Robert C and Batoko, Henri and Bay, Boon-Huat and Beau, Isabelle and Béchet, Daniel M and Begley, Thomas J and Behl, Christian and Behrends, Christian and Bekri, Soumeya and Bellaire, Bryan and Bendall, Linda J and Benetti, Luca and Berliocchi, Laura and Bernardi, Henri and Bernassola, Francesca and Besteiro, Sébastien and Bhatia-Kissova, Ingrid and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Boise, Lawrence H and Bonaldo, Paolo and Boone, David L and Bornhauser, Beat C and Bortoluci, Karina R and Bossis, Ioannis and Bost, Frédéric and Bourquin, Jean-Pierre and Boya, Patricia and Boyer-Guittaut, Michaël and Bozhkov, Peter V and Brady, Nathan R and Brancolini, Claudio and Brech, Andreas and Brenman, Jay E and Brennand, Ana and Bresnick, Emery H and Brest, Patrick and Bridges, Dave and Bristol, Molly L and Brookes, Paul S and Brown, Eric J and Brumell, John H and ... and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Experimentell patologi and Hälsouniversitetet and Cellbiologi
Autophagy, ISSN 1554-8627, 04/2012, Volume 8, Issue 4, pp. 445 - 544
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and... 
stress | vacuole | autolysosome | flux | LC3 | autophagosome | lysosome | phagophore | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Phagophore | Lysosome | Autolysosome | Flux | Autophagosome | Vacuole | Stress | ACTIVATED PROTEIN-KINASE | CHAPERONE-MEDIATED AUTOPHAGY | VACUOLE TARGETING PATHWAY | ENDOPLASMIC-RETICULUM STRESS | ISOLATED RAT HEPATOCYTES | STARVATION-INDUCED AUTOPHAGY | GLUCAGON-INDUCED AUTOPHAGY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | BREAST-CANCER CELLS | BETAINE HOMOCYSTEINE METHYLTRANSFERASE | Biological Assay - methods | Animals | Autophagy - genetics | Models, Biological | Humans | Life Sciences | Cellular Biology | Review | Medical and Health Sciences | Medicin och hälsovetenskap
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4. Full Text Isolation of underivatized amino acids by ion-pair high performance liquid chromatography for precise measurement of nitrogen isotopic composition of amino acids: Development of comprehensive LC×GC/C/IRMS method
by Takano, Yoshinori and Chikaraishi, Yoshito and Ohkouchi, Naohiko
International Journal of Mass Spectrometry, ISSN 1387-3806, 03/2015, Volume 379, pp. 16 - 25
Nitrogen isotopic composition of amino acids has been widely applied to biochemical, ecological, archeological, and biogeochemical studies in an attempt to... 
Ion-pair liquid chromatography | Gas chromatography | Precise 15N/14N measurement | Amino acids | Isotope ratio mass spectrometry | Precise | N measurement | N
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5. Full Text Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes
by Murase, Daiki and Hachiya, Akira and Takano, Kei and Hicks, Rachel and Visscher, Marty O and Kitahara, Takashi and Hase, Tadashi and Takema, Yoshinori and Yoshimori, Tamotsu
Journal of Investigative Dermatology, ISSN 0022-202X, 10/2013, Volume 133, Issue 10, pp. 2416 - 2424
Melanin in the epidermis determines the wide variation in skin color associated with ethnic skin diversity. Ethnic differences exist regarding melanosome loss... 
CELLS | SUBSTITUTE | TYROSINASE | FILOPODIA | MECHANISMS | MELANOGENESIS | BLACK-AND-WHITE | MODEL | HUMAN MELANOCYTES | PIGMENTATION | DERMATOLOGY | Epidermis - metabolism | Humans | Cells, Cultured | Melanoma | African Americans | European Continental Ancestry Group | Male | Autophagy - physiology | Keratinocytes - cytology | Foreskin - cytology | Keratinocytes - metabolism | Skin Neoplasms | Cell Line, Tumor | Adult | Female | Skin Pigmentation - physiology | Melanosomes - metabolism | Infant, Newborn | Epidermis - cytology
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6. Full Text Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation
by Nakamura, Masato, MD, PhD and Iijima, Raisuke, MD, PhD and Ako, Junya, MD, PhD and Shinke, Toshiro, MD, PhD and Okada, Hisayuki, MD, PhD and Ito, Yoshiaki, MD, PhD and Ando, Kenji, MD and Anzai, Hitoshi, MD, PhD and Tanaka, Hiroyuki, MD, PhD and Ueda, Yasunori, MD, PhD and Takiuchi, Shin, MD, PhD and Nishida, Yasunori, MD and Ohira, Hiroshi, MD and Kawaguchi, Katsuhiro, MD, PhD and Kadotani, Makoto, MD, PhD and Niinuma, Hiroyuki, MD, PhD and Omiya, Kazuto, MD, PhD and Morita, Takashi, MD, PhD and Zen, Kan, MD, PhD and Yasaka, Yoshinori, MD, PhD and Inoue, Kenji, MD, PhD and Ishiwata, Sugao, MD, PhD and Ochiai, Masahiko, MD, PhD and Hamasaki, Toshimitsu, MSc, PhD and Yokoi, Hiroyoshi, MD and NIPPON Investigators
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2017, Volume 10, Issue 12, pp. 1189 - 1198
Abstract Objectives The NIPPON (Nobori Dual Antiplatelet Therapy as Appropriate Duration) study was a multicenter randomized investigation of the... 
Cardiovascular | dual antiplatelet therapy | net adverse clinical and cerebrovascular event(s) | biodegradable polymer | stent thrombosis | drug-eluting stent(s) | Myocardial Infarction - mortality | Prospective Studies | Percutaneous Coronary Intervention - mortality | Humans | Middle Aged | Acute Coronary Syndrome - mortality | Male | Prosthesis Design | Aspirin - administration & dosage | Percutaneous Coronary Intervention - instrumentation | Acute Coronary Syndrome - complications | Time Factors | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - adverse effects | Ticlopidine - administration & dosage | Female | Stroke - mortality | Drug Therapy, Combination | Myocardial Infarction - etiology | Platelet Aggregation Inhibitors - adverse effects | Drug-Eluting Stents | Drug Administration Schedule | Japan | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Coronary Artery Disease - mortality | Ticlopidine - analogs & derivatives | Absorbable Implants | Stroke - etiology | Coronary Artery Disease - therapy | Coronary Artery Disease - diagnosis | Coronary Artery Disease - complications | Acute Coronary Syndrome - diagnosis | Intention to Treat Analysis | Acute Coronary Syndrome - therapy | Clopidogrel | Polymers - chemistry | Aged | Hemorrhage - chemically induced | Percutaneous Coronary Intervention - adverse effects | net adverse clinical and erebrovascular event(s) | CARDIAC & CARDIOVASCULAR SYSTEMS | THROMBOSIS | RISK | PERCUTANEOUS CORONARY INTERVENTION | CLOPIDOGREL | PREDICTORS | CLINICAL-TRIALS | COMPLICATIONS | DURATION
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7. Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder
by Hashimoto, Ryota and Nakazawa, Takanobu and Tsurusaki, Yoshinori and Yasuda, Yuka and Nagayasu, Kazuki and Matsumura, Kensuke and Kawashima, Hitoshi and Yamamori, Hidenaga and Fujimoto, Michiko and Ohi, Kazutaka and Umeda-Yano, Satomi and Fukunaga, Masaki and Fujino, Haruo and Kasai, Atsushi and Hayata-Takano, Atsuko and Shintani, Norihito and Takeda, Masatoshi and Matsumoto, Naomichi and Hashimoto, Hitoshi
Journal of Human Genetics, ISSN 1434-5161, 03/2016, Volume 61, Issue 3, pp. 199 - 206
Autism spectrum disorder (ASD) is a complex group of clinically heterogeneous neurodevelopmental disorders with unclear etiology and pathogenesis. Genetic... 
INDIVIDUALS | ENCEPHALOPATHY | NETWORK | DE-NOVO MUTATIONS | GENE | GENETICS & HEREDITY | VERSION | MICE | EXPRESSION | PERVASIVE DEVELOPMENTAL DISORDERS | CHILDREN | Autism Spectrum Disorder - genetics | Cell Line | Genetic Predisposition to Disease | Neurites | Humans | Middle Aged | Male | Exome | Young Adult | Animals | Adult | Female | Mice | Sequence Analysis | Index Medicus
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8. Full Text Five-weekly S-1 plus cisplatin therapy combined with trastuzumab therapy in HER2-positive gastric cancer: a phase II trial and biomarker study (WJOG7212G)
by Miura, Yuji and Sukawa, Yasutaka and Hironaka, Shuichi and Mori, Misuzu and Nishikawa, Kazuhiro and Tokunaga, Shinya and Okuda, Hiroyuki and Sakamoto, Takeshi and Taku, Keisei and Nishikawa, Kazuo and Moriwaki, Toshikazu and Negoro, Yuji and Kimura, Yutaka and Uchino, Keita and Shinozaki, Katsunori and Shinozaki, Hiroharu and Musha, Nobuyuki and Yoshiyama, Hirotsugu and Tsuda, Takashi and Miyata, Yoshinori and Sugimoto, Naotoshi and Shirakawa, Tsuyoshi and Ito, Miki and Yonesaka, Kimio and Yoshimura, Kenichi and Boku, Narikazu and Nosho, Katsuhiko and Takano, Toshimi and Hyodo, Ichinosuke
Gastric Cancer, ISSN 1436-3291, 1/2018, Volume 21, Issue 1, pp. 84 - 95
Five-weekly S-1 plus cisplatin (SP) therapy is the standard care for advanced gastric or esophagogastric junction cancer (GC/EGJC) in East Asia. However, its... 
First-line chemotherapy | Medicine & Public Health | Neuregulin 1 | S-1 | Gastroenterology | Abdominal Surgery | Oncology | Cancer Research | Gastric adenocarcinoma | Surgical Oncology | Trastuzumab | CELLS | MULTICENTER | Neuregulin 1 | RECEPTOR | COMBINATION | CHEMOTHERAPY | BREAST-CANCER | ONCOLOGY | RESISTANCE | GASTROENTEROLOGY & HEPATOLOGY | SERUM HER2 ECD | Antimitotic agents | Oncology, Experimental | Clinical trials | Product development | Research | Antineoplastic agents | Stomach cancer | Cancer | Anorexia | Toxicity | Survival | ErbB-2 protein | Cisplatin | Epidermal growth factor | Response rates | Neuregulin | Antitumor activity | Gastric cancer | Neutropenia | Index Medicus
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9. Full Text Development of a superconducting joint between a GdBa 2 Cu 3 O 7-Δ -coated conductor and YBa 2 Cu 3 O 7-Δ bulk: Towards a superconducting joint between RE (Rare Earth) Ba 2 Cu 3 O 7-Δ -coated conductors
by Jin, Xinzhe and Yanagisawa, Yoshinori and Maeda, Hideaki and Takano, Yoshiki
Superconductor Science and Technology, ISSN 0953-2048, 06/2015, Volume 28, Issue 7
persistent current mode | superconducting joint | crystal growth | bulk | Gd123 coated conductor
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10. Full Text Isolation of underivatized amino acids by ion-pair high performance liquid chromatography for precise measurement of nitrogen isotopic composition of amino acids: Development of comprehensive LCxGC/C/IRMS method
by Takano, Yoshinori and Chikaraishi, Yoshito and Ohkouchi, Naohiko
International Journal of Mass Spectrometry, ISSN 1387-3806, 03/2015, Volume 379, p. 16
Measurement | High performance liquid chromatography | Methods
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11. Full Text Contrasting Magnetic Behaviors in Rhodium‐ and Ruthenium‐Doped Cubic Perovskite SrFeO3: Nearly Ferromagnetic Metal versus Spin‐Glass Insulator
by Kinoshita, Masataka and Sakai, Hideaki and Hayashi, Naoaki and Tokura, Yoshinori and Takano, Mikio and Ishiwata, Shintaro
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2016, Volume 55, Issue 49, pp. 15292 - 15296
The effects of Rh and Ru doping for SrFeO 3 , a helimagnetic metal with a cubic perovskite structure, are studied by magnetic and resistivity measurements.... 
high-pressure synthesis | magnetic properties | ferromagnetism | perovskite phases | unusually high valence ions | MAGNETORESISTANCE | SRFE1-XCOXO3 | WEAK FERROMAGNETISM | CRYSTAL | SRRUO3 | CHEMISTRY, MULTIDISCIPLINARY | SR2FERUO6 | OXIDES | Perovskite | Ferromagnetism | Ruthenium | Magnetic properties