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Journal Article
Science, ISSN 0036-8075, 7/2008, Volume 321, Issue 5887, pp. 408 - 411
When intracellular pathogens invade mammalian hosts, naive CD8(+) T cells differentiate into cytotoxic killers, which lyse infected target cells and secrete... 
T lymphocytes | Spleen | Pathology | Lymphocytic choriomeningitis virus | Cytokines | Neutrophils | Viruses | Reports | Infections | Mice | Genotypes | LINEAGE COMMITMENT | EFFECTOR | CD4 | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISTINCT | DIRECTS | DIFFERENTIATION | TRANSCRIPTION FACTOR | IL-21 | Lymphocytic choriomeningitis virus - immunology | T-Box Domain Proteins - physiology | Arenaviridae Infections - virology | Interferon-gamma - metabolism | Lymphocyte Depletion | CD4-Positive T-Lymphocytes - immunology | Lymphocytic choriomeningitis virus - isolation & purification | Wasting Syndrome - immunology | CD8-Positive T-Lymphocytes - metabolism | Wasting Syndrome - virology | Cell Differentiation | Lymphocytic choriomeningitis virus - physiology | Arenaviridae Infections - immunology | T-Box Domain Proteins - deficiency | Mice, Inbred C57BL | Arenaviridae Infections - pathology | T-Box Domain Proteins - genetics | Mice, Knockout | Antigens, Viral - immunology | Interleukin-17 - metabolism | Animals | Virus Replication | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic | Wasting Syndrome - pathology | Virus diseases | Killer cells | CD8 lymphocytes | Influence | Genetic aspects | Cell-mediated cytotoxicity | DNA binding proteins | Research | Properties | Cell differentiation | Immunology | Biomedical research | Cellular biology | Rodents | Index Medicus | Tc17 | autoimmunity | IL-17 | IL-23 | Th17 | IL-22 | RORγt
Journal Article
by Kahan, Brennan C and Koulenti, Desponia and Arvaniti, Kostoula and Beavis, Vanessa and Campbell, Douglas and Chan, Matthew and Moreno, Rui and Pearse, Rupert M and Beattie, Scott and Clavien, Pierre-Alain and Demartines, Nicolas and Fleisher, Lee A and Grocott, Mike and Haddow, James and Hoeft, Aneas and Holt, Peter and Pritchard, Naomi and Rhodes, Anew and Wijeysundera, Duminda and Wilson, Matt and Ahmed, Tahania and Everingham, Kirsty and Hewson, Russell and Januszewska, Marta and Phull, Mandeep-Kaur and Halliwell, Richard and Shulman, Mark and Myles, Paul and Schmid, Werner and Hiesmayr, Michael and Wouters, Patrick and de Hert, Stefan and Lobo, Suzana and Fang, Xiangming and Rasmussen, Lars and Futier, Emmanuel and Biais, Matthieu and Venara, Aurélien and Slim, Karem and Sander, Michael and Koulenti, Despoina and Chan, Mathew and Kulkarni, Atul and Chana, Susilo and Tantri, Aida and Geddoa, Emad and Abbas, Muntadhar and Della Rocca, Giorgio and Sivasakthi, Datin and Mansor, Marzida and Luna, Pastor and Bouwman, Arthur and Buhre, Wolfgang and Short, Tim and Osinaike, Tunde and Matos, Ricardo and Grigoras, Ioana and Kirov, Mikhail and Protsenko, Denis and Biccard, Bruce and Aldecoa, Cesar and Chew, Michelle and Hofer, Christoph and Hubner, Martin and Ditai, James and Szakmany, Tamas and Fleisher, Lee and Ferguson, Marissa and MacMahon, Michael and Cherian, Ritchie and Currow, Helen and Kanathiban, Kathirgamanathan and Gillespie, David and Pathmanathan, Edward and Phillips, Katherine and Reynolds, Jenifer and Rowley, Joanne and Douglas, Jeanene and Kerridge, Ross and Garg, Sameer and Bennett, Michael and Jain, Megha and Alcock, David and Terblanche, Nico and Cotter, Rochelle and Leslie, Kate and Stewart, Marcelle and Zingerle, Nicolette and Clyde, Antony and Hambidge, Oliver and Rehak, Adam and Cotterell, Sharon and Binh Quan Huynh, Wilson and McCulloch, Timothy and Ben-Menachem, Erez and Egan, Thomas and Cope, Jennifer and Fellinger, Paul and Haselberger, Simone and Holaubek, Caroline and ... and ISOS Grp and International Surgical Outcomes Study (ISOS) group and The International Surgical Outcomes Study (ISOS) group
Intensive care medicine, ISSN 0342-4642, 2017, Volume 43, Issue 7, pp. 971 - 979
Journal Article
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7712, pp. 125 - 129
Somatic mutations in the isocitrate dehydrogenase 2 gene (IDH2) contribute to the pathogenesis of acute myeloid leukaemia (AML) through the production of the... 
LUNG-CANCER | CELLS | GEFITINIB | MUTANT IDH2 | MULTIDISCIPLINARY SCIENCES | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | (R)-2-HYDROXYGLUTARATE | ENASIDENIB | Triazines - therapeutic use | Humans | Glutarates - blood | Isocitrate Dehydrogenase - antagonists & inhibitors | Aminopyridines - chemistry | Aminopyridines - therapeutic use | Enzyme Inhibitors - chemistry | HEK293 Cells | Protein Multimerization - genetics | Leukemia, Myeloid, Acute - drug therapy | Female | Triazines - chemistry | Mutant Proteins - antagonists & inhibitors | Allosteric Site - genetics | Triazines - pharmacology | Allosteric Site - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Mutant Proteins - genetics | Models, Molecular | Isocitrate Dehydrogenase - genetics | Leukemia, Myeloid, Acute - blood | Enzyme Inhibitors - therapeutic use | Disease Progression | Isoleucine - genetics | Drug Resistance, Neoplasm - genetics | Animals | Aminopyridines - pharmacology | Alleles | Glutamine - genetics | Glutarates - metabolism | Mice | Mutation | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Antimitotic agents | Pharmaceutical research | Research | Drug resistance | Antineoplastic agents | Glutamine | Plasma | Pathogenesis | Leukemia | Lung cancer | Cloning | Neutrophils | Kinases | Cancer therapies | Patients | Proteins | Disease resistance | Allosteric properties | Inhibitors | Bone marrow | Dimers | Inhibition | Target acquisition | Isocitrate dehydrogenase | Isoleucine | Neutropenia | Index Medicus | AG-120 | cancer metabolism | leukemia | AG-221 | metabolite | enasidenib | epigenetic | IDH1 | IDH2 | glioma | ivosidenib
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 8, pp. 723 - 732
Journal Article