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Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 7, pp. 590 - 598
Summary Background Currently, crizotinib is the only drug that has been approved for treatment of ALK -rearranged non-small-cell lung cancer (NSCLC). We aimed... 
Hematology, Oncology and Palliative Medicine | FUSION | GENE | ONCOLOGY | C-MET | KINASE | CRIZOTINIB | ANAPLASTIC LYMPHOMA | INHIBITOR | ROS1 | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Piperidines - pharmacokinetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Lung Neoplasms - genetics | Protein Kinase Inhibitors - pharmacokinetics | Carcinoma, Large Cell - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Adenocarcinoma - drug therapy | Maximum Tolerated Dose | Carcinoma, Squamous Cell - drug therapy | Receptor Protein-Tyrosine Kinases - genetics | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Gene Rearrangement | Carbazoles - pharmacokinetics | Aged | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Care and treatment | Oncology, Experimental | Research | College teachers | Lung cancer, Non-small cell | Drug approval | Cancer
Journal Article
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2015, Volume 8, Issue 3, pp. 235 - 245
Journal Article
Journal Article
Respiratory Medicine Case Reports, ISSN 2213-0071, 2017, Volume 20, Issue C, pp. 160 - 163
Abstract MET is a driver oncogene in non-small-cell lung cancer (NSCLC), and its amplification is associated with acquired resistance to epidermal growth... 
Internal Medicine | Pulmonary/Respiratory | Crizotinib | Resistance | Non-small-cell lung cancer | MET amplification | Erlotinib
Journal Article
Journal Article
Journal Article
Annals of Hematology, ISSN 0939-5555, 12/2018, Volume 97, Issue 12, pp. 2345 - 2352
To investigate the prevalence and clinical value of abnormal findings detected via brain magnetic resonance imaging (MRI) in patients with intravascular large... 
Brain | Pons | Medicine & Public Health | Hematology | Magnetic resonance imaging | Oncology | Diagnosis | Intravascular large B-cell lymphoma | MANAGEMENT | INVOLVEMENT | HEMATOLOGY | VARIANT | HYPERTROPHIC PACHYMENINGITIS | Care and treatment | Chemotherapy | Brain research | Oncology, Experimental | Lymphomas | Research | Cancer
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2015, Volume 5, Issue 1, p. 15136
SQAP is a novel and promising anticancer agent that was obtained by structural modifications from a natural compound. SQAP inhibits angiogenesis in vivo... 
LUNG-CANCER | PAXILLIN | TYROSINE PHOSPHORYLATION | TARGETING ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | ALPHA-SULFOQUINOVOSYLMONOACYLGLYCEROL | ENDOTHELIAL-CELLS | PHAGE DISPLAY | POTENT RADIOSENSITIZER | TUMOR ANGIOGENESIS | EXPRESSION | Human Umbilical Vein Endothelial Cells | Focal Adhesion Kinase 1 - genetics | Lung Neoplasms - drug therapy | Carcinoma, Small Cell - genetics | Membrane Glycoproteins - metabolism | Antineoplastic Agents - chemical synthesis | Humans | Membrane Glycoproteins - chemistry | Peroxisomal Multifunctional Protein-2 - chemistry | Peroxisomal Multifunctional Protein-2 - genetics | DNA Repair Enzymes - genetics | Molecular Sequence Data | Glycolipids - chemical synthesis | Lung Neoplasms - pathology | Peptide Library | Carcinoma, Small Cell - enzymology | DNA-Binding Proteins - metabolism | DNA Repair Enzymes - metabolism | Carrier Proteins - chemistry | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Binding Sites | Focal Adhesion Kinase 1 - metabolism | DNA Repair Enzymes - chemistry | Lung Neoplasms - genetics | Amino Acid Sequence | Lung Neoplasms - enzymology | Carcinoma, Small Cell - drug therapy | Glycolipids - pharmacology | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Peroxisomal Multifunctional Protein-2 - metabolism | Membrane Glycoproteins - genetics | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Cell Movement - drug effects | Animals | Carrier Proteins - metabolism | Mice, Nude | Cell Line, Tumor | Protein Binding | Mice | Molecular Docking Simulation | Carcinoma, Small Cell - pathology | Focal Adhesion Kinase 1 - antagonists & inhibitors | Focal Adhesion Kinase 1 - chemistry | Ubiquitin | Phosphorylation | Leukocyte migration | Kinases | Endothelial cells | Cell adhesion & migration | Angiogenesis | Phage display | Proteasomes | Hypoxia | Surface plasmon resonance | Focal adhesion kinase | Umbilical vein | Cell migration | Cancer
Journal Article
Journal Article