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Journal Article
Medicine, ISSN 0025-7974, 06/2018, Volume 97, Issue 23, p. e11084
Journal Article
Investigational New Drugs, ISSN 0167-6997, 4/2019, Volume 37, Issue 2, pp. 291 - 296
... Yusuke Chihara 1 & Koji Date 2 & Yoshizumi Takemura 3 & Nobuyo Tamiya 1 & Yoshihito Kohno 4 & Tatsuya Imabayashi 1 & Yoshiko Kaneko 1 & Tadaaki Yamada 1 & Mikio Ueda... 
Oncology | Medicine & Public Health | Pharmacology/Toxicology | Combination chemotherapy | Paclitaxel | Non-small cell lung cancer | BIWEEKLY PACLITAXEL | MONOTHERAPY | I/II | CHEMOTHERAPY | PHOSPHORYLASE | TRIAL | ONCOLOGY | GASTRIC-CANCER | FLUOROPYRIMIDINE | PHARMACOLOGY & PHARMACY | DIHYDROPYRIMIDINE-DEHYDROGENASE | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Prognosis | Follow-Up Studies | Carcinoma, Squamous Cell - pathology | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Lung Neoplasms - pathology | Male | Oxonic Acid - administration & dosage | Adenocarcinoma - drug therapy | Tissue Distribution | Maximum Tolerated Dose | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Tegafur - administration & dosage | Female | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Paclitaxel - administration & dosage | Drug Combinations | Complications and side effects | Chemotherapy, Combination | Dosage and administration | Research | Lung cancer, Non-small cell | Drug therapy | Toxicity | Lung cancer | Non-small cell lung carcinoma | Diarrhea | Patients | Studies | Chemotherapy | Stomatitis | Older people | Skin | Neutropenia | Cancer | Geriatrics | Index Medicus
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 316
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells. Vasculature in tumors, unlike that in wound healing, is immature and... 
Angiogenesis | Neovascularization | Tumor microenvironment | Cancer therapy | POTENTIAL TARGET | INDUCIBLE FACTOR-I | DENDRITIC CELLS | angiogenesis | neovascularization | cancer therapy | ANTIANGIOGENIC THERAPY | VESSEL CO-OPTION | ONCOLOGY | REGULATORY T-CELLS | tumor microenvironment | ANTI-ANGIOGENIC THERAPY | SUPPRESSOR-CELLS | VASCULAR E-SELECTIN | ENDOTHELIAL GROWTH-FACTOR
Journal Article
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 282
Previously, we reported that nicotine reduces erlotinib sensitivity in a xenograft model of PC9, an epidermal growth factor receptor-tyrosine kinase inhibitor... 
Non-small-cell lung cancer (NSCLC) | Cotinine | Erlotinib resistance | EGFR | Nicotine | nicotine | GEFITINIB | ANGIOGENESIS | cotinine | PROLIFERATION | erlotinib resistance | EGFR-TKI | non-small-cell lung cancer (NSCLC) | MULTIPLE ROLES | ACETYLCHOLINE-RECEPTORS | INHIBITION | METABOLISM | ONCOLOGY | SMOKING HISTORY | GROWTH
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 410
Reports on the use of cryobiopsy (CB) for lung cancer diagnosis are limited. The aims of the present study were to evaluate the safety and usefulness of CB... 
Bronchoscopy | Cell biology | Cryobiopsy | Lung cancer | Ultrasonography | MULTICENTER | ultrasonography | YIELD | INCREASES | OPEN-LABEL | cryobiopsy | bronchoscopy | lung cancer | CELL LUNG-CANCER | cell biology | DABRAFENIB PLUS TRAMETINIB | DISEASES | ONCOLOGY | FORCEPS BIOPSY | CRYOPROBE
Journal Article
Cancer Medicine, ISSN 2045-7634, 04/2019, Volume 8, Issue 4, pp. 1521 - 1529
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 365
Osimertinib is a mutant-selective EGFR inhibitor that is effective against non-small cell lung cancer (NSCLC) in patients with the EGFR-T790M mutation, who are... 
Osimertinib | Biomarker | Retrospective study | EGFR-T790M mutation | Non-small cell lung cancer | non-small cell lung cancer | GEFITINIB | ADENOCARCINOMA | PHASE-III | ACQUIRED-RESISTANCE | T790M | biomarker | ONCOLOGY | osimertinib | GROWTH-FACTOR | AFATINIB | retrospective study | AZD9291
Journal Article
Thoracic Cancer, ISSN 1759-7706, 03/2019, Volume 10, Issue 3, pp. 526 - 532
Background Cancer immunotherapy is under development as a promising alternative strategy for treating advanced non‐small cell lung cancer (NSCLC). However, the... 
Biomarker | bowel movement condition | non‐small cell lung cancer | retrospective study | immunotherapy | non-small cell lung cancer | CONSTIPATION | MELANOMA | ONCOLOGY | RESPIRATORY SYSTEM | MICROBIOME | NIVOLUMAB | DOCETAXEL | Humans | Middle Aged | Fecal Incontinence - chemically induced | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Fecal Incontinence - microbiology | Immunity - drug effects | Carcinoma, Non-Small-Cell Lung - microbiology | Aged, 80 and over | Female | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Kaplan-Meier Estimate | Carcinoma, Non-Small-Cell Lung - epidemiology | Constipation - epidemiology | Immunity - immunology | Constipation - pathology | Genes, cdc - drug effects | C-Reactive Protein - genetics | B7-H1 Antigen - genetics | Constipation - chemically induced | Immunotherapy - adverse effects | B7-H1 Antigen - antagonists & inhibitors | Constipation - microbiology | Gastrointestinal Microbiome - drug effects | Fecal Incontinence - pathology | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Gastrointestinal Microbiome - immunology | Programmed Cell Death 1 Receptor - genetics | Medical colleges | Medical research | Care and treatment | Gastrointestinal agents | Microbiota (Symbiotic organisms) | Analysis | Immunotherapy | Melanoma | Medicine, Experimental | Lung cancer, Small cell | Lung cancer, Non-small cell | Narcotics | Lung cancer | Medical records | Metastasis | Patients | Cancer therapies | Studies | Microbiota | Epidermal growth factor | Hospitals | Biomarkers | Laxatives | Mutation | Constipation | Age | Tumors | Original
Journal Article
Journal Article
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 04/2019, Volume 8, Issue 4, p. 450
Secondary sarcopenia is defined as a decrease in muscle mass due to disease or malnutrition. Several studies have reported that secondary sarcopenia is an... 
non-small cell lung cancer | DEFINITION | SURVIVAL | CACHEXIA | DISTRIBUTION WIDTH | SKELETAL-MUSCLE | MEDICINE, GENERAL & INTERNAL | OBESITY | red blood cell distribution width | psoas major muscle area | TO-LYMPHOCYTE RATIO | SUPPRESSOR-CELLS | OUTCOMES | NIVOLUMAB | sarcopenia
Journal Article
The Oncologist, ISSN 1083-7159, 08/2019, Volume 24, Issue 8, pp. 1033 - e617
Lessons Learned In terms of efficacy and safety, good results were obtained with S‐1 and paclitaxel (PTX) combination therapy. The findings suggest that S‐1... 
TRIAL | 2ND-LINE TREATMENT | ONCOLOGY | DOCETAXEL | CHEMOTHERAPY | I/II | Clinical Trial Results
Journal Article
Respiratory Medicine Case Reports, ISSN 2213-0071, 2018, Volume 25, pp. 261 - 263
NSCLC patients with EGFR mutations respond to EGFR-TKIs; however, the management of refractory tumors to EGFR-TKIs remains unclear. We demonstrated that... 
Liquid biopsy | SCLC transformation | Drug resistance | Repeated genetic testing | EGFR-T790M | Case Report
Journal Article
Journal Article