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by Vimaleswaran, Karani S and Berry, Diane J and Lu, Chen and Tikkanen, Emmi and Pilz, Stefan and Hiraki, Linda T and Cooper, Jason D and Dastani, Zari and Li, Rui and Houston, Denise K and Wood, Andrew R and Michaëlsson, Karl and Vandenput, Liesbeth and Zgaga, Lina and Yerges-Armstrong, Laura M and McCarthy, Mark I and Dupuis, Josée and Kaakinen, Marika and Kleber, Marcus E and Jameson, Karen and Arden, Nigel and Raitakari, Olli and Viikari, Jorma and Lohman, Kurt K and Ferrucci, Luigi and Melhus, Håkan and Ingelsson, Erik and Byberg, Liisa and Lind, Lars and Lorentzon, Mattias and Salomaa, Veikko and Campbell, Harry and Dunlop, Malcolm and Mitchell, Braxton D and Herzig, Karl-Heinz and Pouta, Anneli and Hartikainen, Anna-Liisa and Streeten, Elizabeth A and Theodoratou, Evropi and Jula, Antti and Wareham, Nicholas J and Ohlsson, Claes and Frayling, Timothy M and Kritchevsky, Stephen B and Spector, Timothy D and Richards, J. Brent and Lehtimäki, Terho and Ouwehand, Willem H and Kraft, Peter and Cooper, Cyrus and März, Winfried and Power, Chris and Loos, Ruth J. F and Wang, Thomas J and Järvelin, Marjo-Riitta and Whittaker, John C and Hingorani, Aroon D and Hyppönen, Elina and Genetic Invest Anthropometric Trai and Genetic Investigation of Anthropometric Traits-GIANT Consortium and the Genetic Investigation of Anthropometric Traits (GIANT) consortium and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
PLoS medicine, ISSN 1549-1676, 2013, Volume 10, Issue 2, p. e1001383
BACKGROUND: Obesity is associated with vitamin D deficiency, and both are areas of active public health concern. We explored the causality and direction of the... 
MEDICINE, GENERAL & INTERNAL | INSTRUMENTAL VARIABLES | 25-HYDROXYVITAMIN D | D DEFICIENCY | BODY-MASS INDEX | RISK | GENETIC-VARIANTS | D INSUFFICIENCY | PREVALENCE | WEIGHT | ASSOCIATION | Multivariate Analysis | Humans | Middle Aged | Male | North America | Obesity - genetics | Mendelian Randomization Analysis | Aged, 80 and over | Adult | Female | Obesity - diagnosis | Body Mass Index | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Vitamin D Deficiency - genetics | Risk Assessment | Europe | Risk Factors | Obesity - ethnology | Linear Models | Biomarkers - blood | Evidence-Based Medicine | Vitamin D - blood | Vitamin D Deficiency - ethnology | Vitamin D Deficiency - prevention & control | Phenotype | Vitamin D Deficiency - diagnosis | Obesity - therapy | Vitamin D - analogs & derivatives | Aged | Polymorphism, Single Nucleotide | Obesity | Vitamin D | Physiological aspects | Calcifediol | Social medicine | Alfacalcidol | Research | Health aspects | Studies | Body mass index | Basic Medicine | cardiovascular-disease risk | 25-hydroxyvitamin d | common obesity | body-mass index | prevalence | instrumental variables | Endokrinologi och diabetes | d insufficiency | Medicinska grundvetenskaper | genome-wide association | genetic-variants | d deficiency | Endocrinology and Diabetes
Journal Article
Journal Article
by Shah, Sonia and Henry, Albert and Roselli, Carolina and Lin, Honghuang and Sveinbjörnsson, Garðar and Fatemifar, Ghazaleh and Hedman, Åsa K and Wilk, Jemma B and Morley, Michael P and Chaffin, Mark D and Helgadottir, Anna and Verweij, Niek and Dehghan, Abbas and Almgren, Peter and Andersson, Charlotte and Aragam, Krishna G and Ärnlöv, Johan and Backman, Joshua D and Biggs, Mary L and Bloom, Heather L and Brandimarto, Jeffrey and Brown, Michael R and Buckbinder, Leonard and Carey, David J and Chasman, Daniel I and Chen, Xing and Chen, Xu and Chung, Jonathan and Chutkow, William and Cook, James P and Delgado, Graciela E and Denaxas, Spiros and Doney, Alexander S and Dörr, Marcus and Dudley, Samuel C and Dunn, Michael E and Engström, Gunnar and Esko, Tõnu and Felix, Stephan B and Finan, Chris and Ford, Ian and Ghanbari, Mohsen and Ghasemi, Sahar and Giedraitis, Vilmantas and Giulianini, Franco and Gottdiener, John S and Gross, Stefan and Guðbjartsson, Daníel F and Gutmann, Rebecca and Haggerty, Christopher M and van der Harst, Pim and Hyde, Craig L and Ingelsson, Erik and Jukema, J. Wouter and Kavousi, Maryam and Khaw, Kay-Tee and Kleber, Marcus E and Køber, Lars and Koekemoer, Andrea and Langenberg, Claudia and Lind, Lars and Lindgren, Cecilia M and London, Barry and Lotta, Luca A and Lovering, Ruth C and Luan, Jian’an and Magnusson, Patrik and Mahajan, Anubha and Margulies, Kenneth B and März, Winfried and Melander, Olle and Mordi, Ify R and Morgan, Thomas and Morris, Andrew D and Morris, Andrew P and Morrison, Alanna C and Nagle, Michael W and Nelson, Christopher P and Niessner, Alexander and Niiranen, Teemu and O’Donoghue, Michelle L and Owens, Anjali T and Palmer, Colin N. A and Parry, Helen M and Perola, Markus and Portilla-Fernandez, Eliana and Psaty, Bruce M and Rice, Kenneth M and Ridker, Paul M and Romaine, Simon P. R and Rotter, Jerome I and Salo, Perttu and Salomaa, Veikko and van Setten, Jessica and Shalaby, Alaa A and Smelser, Diane T and Smith, Nicholas L and Stender, Steen and Stott, David J and Svensson, Per and ... and Regeneron Genetics Center and Regeneron Genetics Ctr and et al
Nature communications, ISSN 2041-1723, 2020, Volume 11, Issue 1, pp. 163 - 12
textabstractHeart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic... 
IMPUTATION | OBESITY | METAANALYSIS | CATALOG | MULTIDISCIPLINARY SCIENCES | DISEASE | RISK | LOCI | HYPERTENSION | EPIDEMIOLOGY | RESOURCE | Genome-Wide Association Study | Humans | Risk Factors | Ventricular Function, Left - genetics | Cardiomyopathies - pathology | Heart Failure - genetics | Heart Failure - pathology | Atrial Fibrillation - genetics | Case-Control Studies | Muscle Proteins - genetics | Cardiomyopathies - genetics | Carrier Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Adaptor Proteins, Signal Transducing - genetics | Coronary Artery Disease - genetics | Mendelian Randomization Analysis | Apoptosis Regulatory Proteins - genetics | Microfilament Proteins - genetics | Cardiac arrhythmia | Senescence | Pathogenesis | Cardiovascular disease | Genomes | Risk factors | Body mass index | Randomization | Fibrillation | Failure analysis | Genetic analysis | Heart diseases | Heart failure | Hypertension | Coronary artery | Functional analysis | Risk analysis | Coronary artery disease | Loci | Morbidity | Body mass | Body size | Gene loci | Heritability | Ventricle | Life Sciences | Human health and pathology | Cardiology and cardiovascular system | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
by Hinney, Anke and Kesselmeier, M and Jall, S and Volckmar, A.-L and Föcker, M and Antel, J and Heid, Iris and Winkler, Thomas W and Grant, S.F.A and Guo, Yongli and Bergen, Anew and Grant, Struan and Berrettini, Wade and Hakonarson, Hakon and Herpertz-Dahlmann, B and De Zwaan, M and Herzog, W and Ehrlich, Stefan and Zipfel, S and Egberts, Karin and Adan, R and Brandys, M and Elburg, Annemarie and Boraska Perica, V and Müller, T.D and Tschöp, M.H and Zeggini, Eleftheria and Bulik, C.M and Collier, David and Scherag, A and Hebebrand, J and Tschop, Matthias and Floyd, Jamie and Thornton, Laura and Huckins, L.M and Southam, Lorraine and Rayner, Nigel William and Tachmazidou, Ioanna and Klump, K.L and Treasure, J and Lewis, Cathryn and Schmidt, U and Tozzi, F and Iezebrink, K and Gorwood, P and Kas, Martien and Favaro, A and Santonastaso, P and Fernández-Aranda, F and Gratacos, M and Rybakowski, F and Dmitrzak-Weglarz, M and Kaprio, J and Keski-Rahkonen, A and Raevuori-Helkamaa, A and Furth, Eric and Slof-Op’t Landt, M.C.T and Hudson, J.I and Kaprio, Jaakko and Knudsen, G.P.S and Monteleone, P and Kaplan, A.S and Karwautz, A and Li, D and Komaki, G and Ando, T and Inoko, Hidetoshi and Esko, T and Fischer, Krista and Männik, K and Metspalu, A and Baker, J.H and Cone, R.D and Esko, Tõnu and DeSocio, J.E and Hilliard, C.E and O’Toole, J.K and Pantel, J and Szatkiewicz, J.P and Taico, C and Zerwas, S and Trace, S.E and Davis, Oliver S and Helder, S and Bühren, K and Burghardt, R and Imgart, H and Scherag, Ane and Boni, C and Ramoz, N and Versini, A and Danner, U.N and de Kove, C and Heniks, J and Koeleman, B.P.C and Ophoff, Roel and Strengman, Eric and Bruson, A and Clementi, Maurizio and Degortes, D and ... and WTCCC3 and GCAN and Children's Hosp Philadelphia and GIANT and GIANT, SFA Grant, EGG and GCAN, WTCCC3 and Price Foundation Collaborative Group, Children’s Hospital of Philadelphia/Price Foundation
Molecular psychiatry, ISSN 1359-4184, 02/2017, Volume 22, Issue 2, pp. 192 - 201
textabstractThe maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN,... 
PSYCHIATRY | NEUROSCIENCES | BIOCHEMISTRY & MOLECULAR BIOLOGY | Obesity | Cross-disorder | Shared | Eating disorder | Loci | Bulimia nervosa
Journal Article
by Cousminer, D.L and Berry, D.J and Timpson, N.J and Ang, W and Thiering, E and Byrne, E.M and Taal, H.R and Huikari, V and Bradfield, J.P and Kerkhof, M and Groen-Blokhuis, M.M and Kreiner-Møller, E and Marinelli, M and Holst, C and Leinonen, J.T and Perry, J.R and Surakka, I and Pietilainen, O.P and Kettunen, J and Anttila, V and Kaakinen, M and Sovio, U and Pouta, A and Das, S and Lagou, V and Power, C and Prokopenko, I and Evans, D.M and Kemp, J.P and St Pourcain, B and Ring, S.M and Palotie, A and Kajantie, E and Osmond, C and Lehtimäki, T and Viikari, J.S and Kähönen, M and Warrington, N.M and Lye, S.J and Palmer, L.J and Tiesler, C.M.T and Flexeder, C and Montgomery, G.W and Medland, S.E and Hofman, A and Hakonarson, H and Guxens, M and Bartels, M and Salomaa, V and Adair, L.S and Atalay, M and van Beijsterveldt, C.E.M and Bergen, N and Benke, K.S and Charoen, P and Coin, L and Cooper, C and Davis, O.S and Dedoussis, G.V and Elliott, P and Estivill, X and Feenstra, B and Frayling, T.M and Freathy, R.M and Gaillard, R and Geller, F and Gillman, M.W and Goh, L.K and Hattersley, A.T and Haworth, C.M and Hadley, D and Hedebrand, J and Hinney, A and Hirschhorn, J.N and Hocher, B and Holloway, J.W and Hottenga, J.J and Horikoshi, M and Iñiguez, C and Järvelin, M.R and Kilpeläinen, T.O and Kirin, M and Kowgier, M and Lakka, H.M and Lakka, T.A and Lange, L.A and Lawlor, D.A and Lewin, A and Lindgren, C.M and Lindi, V and Maggi, R and Marsh, J and Melbye, M and Middeldorp, C.M and Millwood, I and Mohlke, K.L and Mook-Kanamori, D.O and Murray, J.C and Nivard, M.G and Nohr, E.A and ...
Human molecular genetics, ISSN 0964-6906, 2013, Volume 22, Issue 13, pp. 2735 - 2747
The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growthfactors.Although... 
Journal Article
Nature (London), ISSN 0028-0836, 2010, Volume 467, Issue 7317, pp. 832 - 838
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide... 
Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Journal of Personalized Medicine, ISSN 2075-4426, 04/2015, Volume 5, Issue 2, pp. 96 - 106
The Estonian population-based biobank, with 52,000 participants' genetic and health data, is the largest epidemiological cohort in the Baltic region.... 
Biobanking | Databases | Estonian Biobank | Re-contacting | Registries | Personalized medicine | Electronic health records | Linking | databases | biobanking | re-contacting | linking | electronic health records | registries | personalized medicine
Journal Article
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