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Journal of the American Society of Nephrology : JASN, ISSN 1046-6673, 2014, Volume 25, Issue 5, pp. 905 - 912
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 396 - 404
Molecules associated with the transforming growth factor beta (TGF-beta) superfamily, such as bone morphogenic proteins (BMPs) and TGF-beta, are key regulators... 
MEDICINE, RESEARCH & EXPERIMENTAL | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE FIBROSIS | DIABETIC-NEPHROPATHY | CELL BIOLOGY | RENAL FIBROSIS | TO-MESENCHYMAL TRANSITION | GROWTH-FACTOR-BETA | TRANSFORMING GROWTH-FACTOR-BETA-2 | BONE MORPHOGENETIC PROTEIN-7 | EXPRESSION | PROGRESSION | Captopril - pharmacology | Bone Morphogenetic Proteins - agonists | Bone Morphogenetic Protein Receptors - genetics | Peptides - pharmacokinetics | Apoptosis - genetics | Smad3 Protein - metabolism | Structure-Activity Relationship | Peptide Library | Fibrosis - metabolism | Smad3 Protein - genetics | Bone Morphogenetic Proteins - metabolism | Inflammation - metabolism | Kidney - metabolism | Peptides - chemical synthesis | Peptides - metabolism | Regeneration - genetics | Epithelial-Mesenchymal Transition | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Kidney Tubules - metabolism | Diabetic Nephropathies - pathology | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Diabetic Nephropathies - metabolism | Bone Morphogenetic Protein Receptors - metabolism | Bone Morphogenetic Protein Receptors, Type I - genetics | Rats | Bone Morphogenetic Protein Receptors, Type I - metabolism | Kidney - injuries | Rats, Sprague-Dawley | Bone Morphogenetic Protein Receptors, Type II - metabolism | Animals | Transforming Growth Factor beta - genetics | Inflammation - genetics | Mice | Transforming Growth Factor beta - metabolism | Physiological aspects | Cellular signal transduction | Research | Kidney diseases | Protein kinases | Risk factors | Signal transduction | Pharmacology | Kinases | Gene expression | Rodents | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 02/2015, Volume 116, Issue 5, pp. 857 - 866
RATIONALE:Endocardial fibroelastosis (EFE) is a unique form of fibrosis, which forms a de novo subendocardial tissue layer encapsulating the myocardium and... 
Endocardium | Endothelial cell | Congenital heart disease | Hypoplastic left heart syndrome | Endocardial fibroelastosis | Fibrosis | TRANSFORMATION | DE-NOVO | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | VIRUS | hypoplastic left heart syndrome | endothelial cell | AORTIC-VALVE | IDENTIFICATION | endocardial fibroelastosis | RARE VARIANTS | endocardium | LEFT-HEART SYNDROME | MEMBRANE-PROTEIN 1 | congenital heart disease | PERIPHERAL VASCULAR DISEASE | fibrosis | MUTATIONS | HEMATOLOGY | Recombinant Proteins - therapeutic use | Endocardial Fibroelastosis - drug therapy | Bone Morphogenetic Protein 7 - genetics | Humans | Hypoplastic Left Heart Syndrome - surgery | Rats, Inbred Lew | Infant | Cell Transdifferentiation - genetics | Endocardium - pathology | Antigens, CD - genetics | DNA Methylation | Cell Transdifferentiation - physiology | Gene Expression Regulation, Developmental | Cadherins - genetics | Genes, Reporter | Infant, Newborn | Animals, Newborn | Promoter Regions, Genetic | Epithelium - pathology | Mice, Inbred C57BL | Cells, Cultured | Transforming Growth Factor beta - physiology | Rats | Transplantation, Heterotopic | Heart Transplantation | Smad Proteins - genetics | Smad Proteins - physiology | Animals | Hypoplastic Left Heart Syndrome - pathology | Biomarkers | Signal Transduction - physiology | Mice | Bone Morphogenetic Protein 7 - physiology | Mesoderm - pathology | Bone Morphogenetic Protein 7 - therapeutic use | Endocardial Fibroelastosis - pathology | Index Medicus | endothelial mesenchymal transition
Journal Article
EBioMedicine, ISSN 2352-3964, 01/2015, Volume 2, Issue 1, pp. 19 - 36
Progression of chronic kidney disease remains a principal problem in clinical nephrology and there is a pressing need for novel therapeutics and biomarkers.... 
Epigenetics | DNA methylation | RASAL1 | Ten-Eleven Translocation (TET) | De-methylation | Fibrosis | MEDICINE, RESEARCH & EXPERIMENTAL | SEVERE HYPERTENSION | NEPHROPATHY | RENAL FIBROGENESIS | STANDARD TRIPLE THERAPY | FIBROBLAST ACTIVATION | CONGESTIVE HEART-FAILURE | DNA | GROWTH-FACTOR | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0137028 - e0137028
Rare neural cell adhesion molecule (NCAM) positive cells have been previously described within the normal human adult kidney interstitium, speculating that... 
ACTIVATION | STRUCTURAL BASIS | NCAM | REGENERATION | MULTIDISCIPLINARY SCIENCES | MYOFIBROBLASTS | MECHANISMS | IDENTIFICATION | BINDING | FIBROBLASTS | FGFR1 | Matrix Metalloproteinase 2 - metabolism | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Fibrosis - metabolism | RNA, Messenger - metabolism | Kidney - metabolism | Matrix Metalloproteinase 9 - metabolism | Protein Isoforms - metabolism | Proteins - metabolism | Up-Regulation - physiology | Neural Cell Adhesion Molecules - metabolism | Integrin alpha5beta1 - metabolism | Kidney Diseases - metabolism | Care and treatment | Fibrosis | Physiological aspects | Development and progression | Fibroblast growth factors | Genetic aspects | Research | Risk factors | Fibroblast growth factor | Nephrology | Matrix metalloproteinases | Transplants & implants | Homeostasis | Interstitial cells | Kinases | Tissues | Cell adhesion molecules | Cell adhesion & migration | Proteins | Epididymis | Rodents | Cell adhesion | Fibroblasts | Extracellular matrix | Fibroblast growth factor receptor 1 | Neural cell adhesion molecule | Kidneys | Rheumatology | Gene expression | Adhesion | Gelatinase B | Polymerase chain reaction | Studies | Pathology | Overexpression | Biopsy | Isoforms | Kidney diseases | Immunofluorescence | Clear cell-type renal cell carcinoma | Kidney transplantation | Tumors | Index Medicus
Journal Article
Journal Article
FRONTIERS IN MEDICINE, ISSN 2296-858X, 08/2018, Volume 5, p. 224
Background: Valproic acid ( VPA) has been approved for the treatment of seizure disorders. It is also commonly used in psychiatric disorders, such as... 
extracorporeal treatment | CARNITINE | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | OVERDOSE | hemodialysis | TOXICITY | valproic acid | HEMOPERFUSION | intoxication | hemodiafiltration | Divalproex | Care and treatment | Usage | Epilepsy | Drunkenness (Criminal law) | Research | Valproic acid | Health aspects
Journal Article
Fibrogenesis and Tissue Repair, ISSN 1755-1536, 04/2015, Volume 8, Issue 1, pp. 6 - 6
While kidney injury is associated with re-expression of numerous Wnt ligands and receptors, molecular mechanisms which underlie regulation of distinct Wnt... 
Fibrosis | Cilia | Epithelial
Journal Article