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FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 11/2018, Volume 8, p. 530
Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced... 
IMMUNITY | nivolumab | melanoma | OPEN-LABEL | BRAF | UNTREATED MELANOMA | prediction of efficacy | THERAPY | TAMs | ONCOLOGY | INFLAMMATION | sCD163 | MUTATION | TUMOR-ASSOCIATED MACROPHAGES | IPILIMUMAB | Prognosis | Patient outcomes | Melanoma | Physiological aspects | Biological markers | Drug therapy | Health aspects | Skin cancer
Journal Article
Nature Materials, ISSN 1476-1122, 2015, Volume 14, Issue 3, pp. 330 - 336
Organic compounds that exhibit highly efficient, stable blue emission are required to realize inexpensive organic light-emitting diodes for future displays and... 
LIGHT-EMITTING-DIODES | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MOLECULAR-ORBITAL METHODS | MATERIALS SCIENCE, MULTIDISCIPLINARY | COMPLEXES | CHEMISTRY, PHYSICAL | DEVICES | ABSORPTION | SINGLET | Studies | Fluorescence | Luminescence | Activated | Decay rate | Oscillator strengths | Emission | Illumination | Displays | Molecular orbitals | Electroluminescence
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2018, Volume 66, Issue 3, pp. 243 - 250
Phosphodiesterase (PDE) 10A is a dual hydrolase of cAMP and cGMP and highly expressed in striatal medium spiny neurons. Inhibition of PDE10A modulates the... 
conditioned avoidance response (CAR) | stilbene | quinoxaline | schizophrenia | pyrimidine | phosphodiesterase (PDE) 10A | Phosphodiesterase (PDE) 10A | Schizophrenia | Conditioned avoidance response (CAR) | Quinoxaline | Pyrimidine | Stilbene | DESIGN | CHEMISTRY, MEDICINAL | HYDROLYZES | PHOSPHORYLATION | CHEMISTRY, MULTIDISCIPLINARY | PHOSPHODIESTERASE PDE10A | POTENT | AVANAFIL | CGMP | PHARMACOLOGY & PHARMACY | DEFICITS | ERECTILE DYSFUNCTION | CAMP | Phosphoric Diester Hydrolases - metabolism | Pyrimidines - chemical synthesis | Phosphodiesterase Inhibitors - pharmacology | Quinoxalines - chemistry | Rats | Crystallography, X-Ray | Structure-Activity Relationship | Pyrimidines - pharmacology | Molecular Dynamics Simulation | Pyrimidines - chemistry | Phosphoric Diester Hydrolases - chemistry | Quinoxalines - pharmacology | Animals | Phosphodiesterase Inhibitors - metabolism | Inhibitory Concentration 50 | Avoidance Learning - drug effects | Phosphodiesterase Inhibitors - chemistry | Drug Evaluation, Preclinical | Quinoxalines - chemical synthesis | Binding Sites | Brain | Mental disorders | Homology | Optimization | Psychosis | Rodents | Cyclic GMP | Neostriatum | Conditioning | Phosphodiesterase | Signs and symptoms | Hydrolase | Neurons | Cyclic AMP | Quinoxalines | Erectile dysfunction | Pharmacology | Spiny neurons | Penetration | Inhibitors | Avoidance behavior | Pharmacokinetics | Tetrahydro-2H-pyran
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 01/2020, Volume 10, Issue 1, pp. 838 - 12
The hook length of the flagellum is controlled to about 55nm in Salmonella. The flagellar type III protein export apparatus secretes FliK to determine hook... 
MOLECULAR RULER | EFFICIENT EXPORT | SUBSTRATE-SPECIFICITY | T3S4 DOMAIN | MULTIDISCIPLINARY SCIENCES | SALMONELLA-TYPHIMURIUM | COMPONENTS | NEEDLE LENGTH | TERMINAL CYTOPLASMIC DOMAIN | HOOK-LENGTH CONTROL | FLHA | Proteins | Salmonella | Clonal deletion | Substrate specificity | Hook protein | Flagella | Protein transport
Journal Article
Journal Article
Physical Review B - Condensed Matter and Materials Physics, ISSN 1098-0121, 03/2015, Volume 91, Issue 9
The layered compound alpha-RuCl3 is composed of a honeycomb lattice of magnetic Ru3+ ions with the 4d(5) electronic state. We have investigated the magnetic... 
PHYSICS, CONDENSED MATTER | RESONANCE | SUPEREXCHANGE INTERACTION | NEUTRON-DIFFRACTION | TRICHLORIDE | IONS | NIBR2 | CRYSTAL | CRCL3 | SPIN-HAMILTONIAN PARAMETERS
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 4, pp. 615 - 619
The purpose of this study was to evaluate the association between therapy-induced hemoglobin (Hb) decreasing rapidity and severity with erythrocyte inosine... 
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2018, Volume 57, Issue 21, pp. 6136 - 6140
A Pd‐Au alloy efficiently catalyzed the [2+2+2] cycloaddition of substituted alkynes. Whereas monometallic Pd and Au catalysts were totally ineffective, Pd‐Au... 
nanoparticles | heterogeneous catalysis | Pd-Au alloys | alkynes | [2+2+2] cycloaddition | BENZENE | CARBON | ACETYLENE | COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | NANOCLUSTERS | SYNERGISTIC CATALYSIS | CHEMISTRY | PD SURFACE | Palladium catalysts | Nanoparticles | Heterogeneous catalysis | Palladium | Alloys | Substitutes | Palladium base alloys | Gold | Cycloaddition | Catalysts | Aromatic compounds | Catalysis | Alkynes
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 09/2019, Volume 55, Issue 68, pp. 10162 - 10165
Peripheral π-expansion of carbazole-based porphyrins was achieved for the first time by the Pt-catalyzed cyclization and the incorporation of a benzocarbazole... 
Journal Article
ISSN 1359-7345, 8/2019, Volume 55, Issue 68, pp. 1162 - 1165
Peripheral π-expansion of carbazole-based porphyrins was achieved for the first time by the Pt-catalyzed cyclization and the incorporation of a benzocarbazole... 
Journal Article
Materials Letters, ISSN 0167-577X, 02/2019, Volume 237, pp. 96 - 100
•The Pt nanoparticles loaded on carbon black particles showed monoclinically strained structures.•No correlation was observed between the monoclinic lattice... 
Nanoparticles | Carbon black | Platinum | FIB | Crystal structure | HRTEM | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | Crystal lattices | Monoclinic lattice | Lattice parameters | Carbon | Ion beams | Unit cell | Transmission electron microscopy | Image transmission | Atomic structure | Electrons | Structural analysis
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2019, Volume 55, Issue 68, pp. 10162 - 10165
Peripheral π-expansion of carbazole-based porphyrins was achieved for the first time by the Pt-catalyzed cyclization and the incorporation of a benzocarbazole... 
Carbazoles | Conjugation | Crystallography | Porphyrins
Journal Article
Zoo Biology, ISSN 0733-3188, 11/2019, Volume 38, Issue 6, pp. 490 - 497
Despite increasing interest in the behavior of zoo animals, studies of nocturnal behavior of zoo animals are limited. In this study, we investigated the... 
sleep | paradoxical sleep | season | behavior | giraffe | parturition | Animals, Zoo | Animals | Behavior, Animal - physiology | Female | Male | Antelopes - physiology | Seasons | Sleep - physiology | Torso | Parturition | Night | Summer | Sleep (REM) | Zoo animals | Posture | Seasonal variations | Sleep | Winter | Animal behavior | Infrared cameras | Behavior
Journal Article
ChemCatChem, ISSN 1867-3880, 01/2020, Volume 12, Issue 2, pp. 455 - 458
: Supported Pd nanoparticles catalyzed the reductive cycloisomerization of diynes to give 1,3‐dienes, and subsequent intermolecular [4+2] cycloaddition with... 
Heterogeneous catalyst | Reductive cycloisomerization | Palladium | [4+2] cycloaddition | 1,6-ENYNES | SILYLATIVE CYCLIZATION | HYDROGENATION | DIELS-ALDER REACTION | CHEMISTRY, PHYSICAL | DIMERIZATION | 1,6-DIYNES
Journal Article