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ChemBioChem, ISSN 1439-4227, 10/2019, Volume 20, Issue 20, pp. 2533 - 2534
Bottom‐up synthetic biology uses both biological and artificial chemical building blocks to create biomimetic systems, including artificial cells. Existing and... 
Organic chemistry | Synthetic biology | Biology | New technology | Biomimetics | Microfluidics
Journal Article
Current Opinion in Colloid & Interface Science, ISSN 1359-0294, 12/2016, Volume 26, pp. 50 - 57
In this review, we examine the interaction of nucleic acids with cell-like structures based on liquid–liquid phase separation of charged molecules (complex... 
Coacervate | Self-assembly | Protocells | Therapeutics | Lipid vesicle | Drug delivery | Nucleic acids | Synthetic cells | RNA | CHEMISTRY, PHYSICAL | LIQUID DROPLETS | COMPLEX COACERVATION | DELIVERY | PHASE-TRANSITION | GENE-EXPRESSION | EXOSOMES | SYSTEMS | SIRNA | PROTEINS | Usage | Analysis
Journal Article
Angewandte Chemie (International ed. in English), ISSN 1433-7851, 01/2020
In situ, reversible coacervate formation within lipid vesicles represents a key step in the development of responsive synthetic cellular models. Here we... 
Journal Article
ISSN 1359-7345, 1/2018, Volume 54, Issue 3, pp. 287 - 29
Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets, based on bovine serum albumin and glucose oxidase conjugated... 
Journal Article
NATURE CHEMISTRY, ISSN 1755-4330, 06/2014, Volume 6, Issue 6, pp. 527 - 533
Mechanisms of prebiotic compartmentalization are central to providing insights into how protocellular systems emerged on the early Earth. Protocell models are... 
COMPLEX | MACROMOLECULES | VESICLES | BEHAVIOR | ENCAPSULATION | POLYMER | CHEMISTRY | VISCOSITY | DRIVEN | CHEMISTRY, MULTIDISCIPLINARY | DROPLETS
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 3, pp. 287 - 290
Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets, based on bovine serum albumin and glucose oxidase conjugated... 
BIOINORGANIC PROTOCELLS | MODEL | CHEMISTRY, MULTIDISCIPLINARY | MEMBRANE | POLYMER | Glucose oxidase | Flow velocity | Serum albumin | Droplets | Microfluidics
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3643 - 9
Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via complex coacervation, which may have... 
PHASE-SEPARATION | CELLS | IN-VITRO | PROTEIN | CLEAVING HAMMERHEAD RIBOZYMES | MOBILITY | MULTIDISCIPLINARY SCIENCES | COMPLEX COACERVATION | MODEL | VIROID RNA | DROPLETS | Cell Compartmentation | Cellular Microenvironment | Catalysis | Origin of Life | Artificial Cells | RNA, Catalytic - metabolism | Coacervation | Phase separation | Oligonucleotides | Ribonucleic acid--RNA | Polymers | Molecular weight | Weight
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 3, pp. 287 - 290
Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets, based on bovine serum albumin and glucose oxidase conjugated... 
Journal Article
ISSN 1744-683X, 2/2015, Volume 11, Issue 1, pp. 1991 - 1997
Non-equilibrium pathways of lyotropic phase transitions such as the lamellar to inverse bicontinuous cubic phase transition are important dynamical processes... 
Journal Article
Journal Article
ISSN 1744-683X, 7/2013, Volume 9, Issue 31, pp. 7647 - 7656
The spontaneous phase separation of peptide/nucleotide droplets in water produces membrane-free chemically organized micro-compartments that offer new... 
Journal Article
Soft Matter, ISSN 1744-683X, 08/2013, Volume 9, Issue 31, pp. 7647 - 7656
The spontaneous phase separation of peptide/nucleotide droplets in water produces membrane-free chemically organized micro-compartments that offer new... 
COMPLEX | POLYMER SCIENCE | PHYSICS, MULTIDISCIPLINARY | VESICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | STEP | SELF-REPRODUCTION | ARTIFICIAL CELL | ENZYME CATALYSIS | MODELS | POLYMER | DONOR-ACCEPTOR SYSTEMS | ATP | Uptakes | Microscopy | Peptides | Fluorescence | Droplets | Dispersions | Nucleotides
Journal Article
Soft Matter, ISSN 1744-683X, 03/2015, Volume 11, Issue 10, pp. 1991 - 1997
Non-equilibrium pathways of lyotropic phase transitions such as the lamellar to inverse bicontinuous cubic phase transition are important dynamical processes... 
POLYMER SCIENCE | PHYSICS, MULTIDISCIPLINARY | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | X-RAY-SCATTERING | MODEL | MEMBRANE-FUSION | PRESSURE | TEMPERATURE | SURFACE | INTERMEDIATE | PROTEINS
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 07/2015, Volume 51, Issue 57, pp. 11429 - 11432
Cell-free gene expression of a fluorescent protein (mCherry) is demonstrated within the molecularly crowded matrix of a polysaccharide/polypeptide coacervate. 
Proteins | Polysaccharides | Polypeptides | Gene expression
Journal Article
Langmuir, ISSN 0743-7463, 09/2012, Volume 28, Issue 36, pp. 13018 - 13024
Monoacylglycerol based lipids are highly important model membrane components and attractive candidates for drug encapsulation and as delivery agents. However,... 
X-RAY | CHEMISTRY, PHYSICAL | SURFACTANT | CHEMISTRY, MULTIDISCIPLINARY | BEHAVIOR | MATERIALS SCIENCE, MULTIDISCIPLINARY | Thermodynamics | Glycerides - chemistry | Water - chemistry | Membranes, Artificial | Models, Molecular | Hydrostatic Pressure | Phase Transition
Journal Article
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