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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2016, Volume 194, Issue 7, pp. 878 - 885
Obstructive sleep apnea is a state-dependent disease. One of the key factors that triggers upper airway collapse is decreased pharyngeal dilator muscle... 
Norepinephrine reuptake inhibitor | Pharmacological treatment | Pharyngeal dilator muscle | Sleep-disordered breathing | norepinephrine reuptake inhibitor | pharmacological treatment | sleep-disordered breathing | Original | pharyngeal dilator muscle
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 05/2018, Volume 197, Issue 9, pp. 1187 - 1197
Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis of a patient's own phenotypic causes ("traits") if a clinically... 
Pathophysiology | Personalized medicine | Endotype | RESPONSIVENESS | UPPER AIRWAY COLLAPSIBILITY | SLOW-WAVE | MECHANISMS | HYPOPNEA | personalized medicine | INDIVIDUALS | PRESSURE | endotype | RESPIRATORY SYSTEM | pathophysiology | LOOP GAIN | TRAITS | SEVERITY | CRITICAL CARE MEDICINE | Respiratory therapy | Automation | Compensation | Physiology | Sleep apnea | Patients | Methods | Original
Journal Article
The European respiratory journal, ISSN 0903-1936, 02/2018, Volume 51, Issue 2, pp. 1701419 - 1701419
In some individuals with obstructive sleep apnoea (OSA), the palate prolapses into the velopharynx during expiration, limiting airflow through the nose or... 
ENDOSCOPY | STIMULATION | VENTILATION | RESPIRATORY SYSTEM | RESPIRATION | RESISTANCE | POSITIVE AIRWAY PRESSURE | COLLAPSIBILITY | HYPERTENSION | ASSOCIATION | LUNG-VOLUME | Epiglottis | Sleep disorders | Tongue | Sleep | Apnea | Nose | Palate | Sleep apnea | Endoscopy | Respiration | Pharynx | Pressure
Journal Article
Journal Article
European Respiratory Journal, ISSN 0903-1936, 09/2017, Volume 50, Issue 3, pp. 1700345 - 1700345
Obstructive sleep apnoea (OSA) is characterised by pharyngeal obstruction occurring at different sites. Endoscopic studies reveal that epiglottic collapse... 
SURGERY | ENDOSCOPY | PRESSURE | INSPIRATORY FLOW SHAPES | RESPIRATORY SYSTEM | HYPOXEMIA | AIRWAY-OBSTRUCTION | Respiratory tract | Sleep disorders | Sleep | Apnea | Sleep apnea | Endoscopy | Respiration | Pharynx | Pressure | Sleep deprivation
Journal Article
Journal Article
European Heart Journal, ISSN 0195-668X, 09/2019, Volume 40, Issue 35, pp. 2989 - 2990
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 11/2019, Volume 8, Issue 11, p. 1846
Obstructive sleep apnea (OSA) is a highly prevalent condition with few therapeutic options. To date there is no approved pharmacotherapy for this disorder, but... 
DISCHARGE PATTERNS | AROUSAL THRESHOLD | SLOW-WAVE | RESPIRATORY ACTIVITY | OSA pharmacotherapy | L-TRYPTOPHAN | MEDICINE, GENERAL & INTERNAL | GENIOGLOSSUS MUSCLE-ACTIVITY | DOUBLE-BLIND | precision medicine | SUPPLEMENTAL OXYGEN | OSA phenotypes | POSITIVE AIRWAY PRESSURE | ROSTRAL FLUID SHIFT | OSA endotypes | osa phenotypes | osa endotypes | osa pharmacotherapy
Journal Article