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NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1869 - 9
Whole-genome sequencing (WGS) is becoming widely used in clinical medicine in diagnostic contexts and to inform treatment choice. Here we evaluate the... 
GENETIC-VARIATION | MUTATIONS | LEUKEMIA | SPECTRUM | MULTIDISCIPLINARY SCIENCES | RESOURCE
Journal Article
by Figlioli, Gisella and Bogliolo, Massimo and Catucci, Irene and Caleca, Laura and Lasheras, Sandra Viz and Pujol, Roser and Kiiski, Johanna I and Muranen, Taru A and Barnes, Daniel R and Dennis, Joe and Michailidou, Kyriaki and Bolla, Manjeet K and Leslie, Goska and Aalfs, Cora M and Adank, Muriel A and Adlard, Julian and Agata, Simona and Cadoo, Karen and Agnarsson, Bjarni A and Ahearn, Thomas and Aittomäki, Kristiina and Ambrosone, Christine B and Andrews, Lesley and Anton-Culver, Hoda and Antonenkova, Natalia N and Arndt, Volker and Arnold, Norbert and Aronson, Kristan J and Arun, Banu K and Asseryanis, Ella and Auber, Bernd and Auvinen, Päivi and Azzollini, Jacopo and Balmaña, Judith and Barkardottir, Rosa B and Barrowdale, Daniel and Barwell, Julian and Beane Freeman, Laura E and Beauparlant, Charles Joly and Beckmann, Matthias W and Behrens, Sabine and Benitez, Javier and Berger, Raanan and Bermisheva, Marina and Blanco, Amie M and Blomqvist, Carl and Bogdanova, Natalia V and Bojesen, Anders and Bojesen, Stig E and Bonanni, Bernardo and Borg, Ake and Brady, Angela F and Brauch, Hiltrud and Brenner, Hermann and Brüning, Thomas and Burwinkel, Barbara and Buys, Saundra S and Caldés, Trinidad and Caliebe, Almuth and Caligo, Maria A and Campa, Daniele and Campbell, Ian G and Canzian, Federico and Castelao, Jose E and Chang-Claude, Jenny and Chanock, Stephen J and Claes, Kathleen B. M and Clarke, Christine L and Collavoli, Anita and Conner, Thomas A and Cox, David G and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and de la Hoya, Miguel and Devilee, Peter and Diez, Orland and Ding, Yuan Chun and Dite, Gillian S and Ditsch, Nina and Domchek, Susan M and Dorfling, Cecilia M and dos-Santos-Silva, Isabel and Durda, Katarzyna and Dwek, Miriam and Eccles, Diana M and Ekici, Arif B and Eliassen, A. Heather and Ellberg, Carolina and Eriksson, Mikael and Evans, D. Gareth and Fasching, Peter A and Figueroa, Jonine and Flyger, Henrik and Foulkes, William D and Friebel, Tara M and Friedman, Eitan and Gabrielson, Marike and Gaddam, Pragna and Gago-Dominguez, Manuela and ... and ABCTB Investigators and KConFab and GEMO Study Collaborators
npj Breast Cancer, ISSN 2374-4677, 12/2019, Volume 5, Issue 1, pp. 1 - 14
Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and... 
Consortia | Medical research | Hospitals | Health services | Genes | Hormone replacement therapy | Breast cancer | Health risk assessment | Chromosomes | Deoxyribonucleic acid--DNA | Risk factors
Journal Article
by Blok, Lot Snijders and Rousseau, Justine and Twist, Joanna and Ehresmann, Sophie and Takaku, Motoki and Venselaar, Hanka and Rodan, Lance H and Nowak, Catherine B and Douglas, Jessica and Swoboda, Kathryn J and Steeves, Marcie A and Sahai, Inderneel and Stumpel, Connie T R M and Stegmann, Alexander P A and Wheeler, Patricia and Willing, Marcia and Fiala, Elise and Kochhar, Aaina and Gibson, William T and Cohen, Ana S A and Agbahovbe, Ruky and Innes, A Micheil and Au, P Y Billie and Rankin, Julia and Anderson, Ilse J and Skinner, Steven A and Louie, Raymond J and Warren, Hannah E and Afenjar, Alexandra and Keren, Boris and Nava, Caroline and Buratti, Julien and Isapof, Arnaud and Rodriguez, Diana and Lewandowski, Raymond and Propst, Jennifer and van Essen, Ton and Choi, Murim and Lee, Sangmoon and Chae, Jong H and Price, Susan and Schnur, Rhonda E and Douglas, Ganka and Wentzensen, Ingrid M and Zweier, Christiane and Reis, André and Bialer, Martin G and Moore, Christine and Koopmans, Marije and Brilstra, Eva H and Monroe, Glen R and van Gassen, Koen L I and van Binsbergen, Ellen and Newbury-Ecob, Ruth and Bownass, Lucy and Bader, Ingrid and Mayr, Johannes A and Wortmann, Saskia B and Jakielski, Kathy J and Strand, Edythe A and Kloth, Katja and Bierhals, Tatjana and Roberts, John D and Petrovich, Robert M and Machida, Shinichi and Kurumizaka, Hitoshi and Lelieveld, Stefan and Pfundt, Rolph and Jansen, Sandra and Deriziotis, Pelagia and Faivre, Laurence and Thevenon, Julien and Assoum, Mirna and Shriberg, Lawrence and Kleefstra, Tjitske and Brunner, Han G and Wade, Paul A and Fisher, Simon E and Campeau, Philippe M and DDD study and The DDD study
Nature communications, ISSN 2041-1723, 02/2019, Volume 10, Issue 1, pp. 883 - 4
The original version of this Article contained an error in the spelling of the author Laurence Faivre, which was incorrectly given as Laurence Faive. This has... 
DNA helicase | Neurodevelopmental disorders | Mutation
Journal Article
Genome medicine, ISSN 1756-994X, 07/2019, Volume 11, Issue 1, pp. 46 - 12
A multi-disciplinary approach to promote engagement, inform decision-making and support clinicians and patients is increasingly advocated to realise the... 
Rare diseases | Decision-making | Care and treatment | Analysis | Genetic research | Genetic aspects | Patients | Exome | Next-generation sequencing | Multidisciplinary team | Genome sequencing | Genetic disease
Journal Article
by Jiang, Xia and Jiang, Xia and Finucane, Hilary K and Finucane, Hilary K and Schumacher, Fredrick R and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Tyrer, Jonathan P and Han, Younghun and Han, Younghun and Michailidou, Kyriaki and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Aldrich, Melinda C and Andrew, Angeline S and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Anton-Culver, Hoda and Antoniou, Antonis C and Antoniou, Antonis C and Antonenkova, Natalia N and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Aronson, Kristan J and Arun, Banu K and Arun, Banu K and Bandera, Elisa V and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benitez, Javier and Benlloch, Sara and Benlloch, Sara and Berchuck, Andrew and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Bien, Stephanie A and Blomqvist, Carl and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brenton, James D and Brook, Mark N and Brook, Mark N and Brunet, Joan and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Buchanan, Daniel D and Burwinkel, Barbara and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caldés, Trinidad and Caligo, Maria A and Caligo, Maria A and Campbell, Ian and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Cannon-Albright, Lisa and Campa, Daniele and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Carvalho, André L and Chan, Andrew T and Chan, Andrew T and Chang-Claude, Jenny and Chang-Claude, Jenny and Chanock, Stephen J and Chanock, Stephen J and Chen, Chu and ... and Medicinska fakulteten and Klinisk kemi and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 431 - 23
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association... 
BREAST-CANCER | LUNG-CANCER | RISK-FACTORS | PARTITIONING HERITABILITY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | MENDELIAN RANDOMIZATION | CELL-TYPES | GENOME-WIDE ASSOCIATION | Lung Neoplasms - ethnology | Colorectal Neoplasms - genetics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Prostatic Neoplasms - diagnosis | Case-Control Studies | Colorectal Neoplasms - diagnosis | Ovarian Neoplasms - ethnology | Inheritance Patterns | Ovarian Neoplasms - genetics | Mental Disorders - genetics | Prostatic Neoplasms - genetics | Smoking - physiopathology | Head and Neck Neoplasms - ethnology | Female | Neoplasm Proteins - genetics | Breast Neoplasms - ethnology | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - ethnology | Ovarian Neoplasms - diagnosis | European Continental Ancestry Group | Smoking - genetics | Prostatic Neoplasms - ethnology | Head and Neck Neoplasms - pathology | Mental Disorders - physiopathology | Smoking - ethnology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Head and Neck Neoplasms - diagnosis | Head and Neck Neoplasms - genetics | Breast Neoplasms - diagnosis | Mental Disorders - ethnology | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Lung Neoplasms - diagnosis | Enrichment | Correlation | Statistical analysis | Ovarian carcinoma | Mental disorders | Lung cancer | Colorectal carcinoma | Genomes | Breast cancer | Regulatory sequences | Ovarian cancer | Etiology | Breast | Heritability | Neck | Solid tumors | Prostate cancer | Prostate | Cancer | Smoking | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
IMPLEMENTATION SCIENCE, ISSN 1748-5908, 08/2019, Volume 14, Issue 1, pp. 84 - 14
Journal Article
MALARIA JOURNAL, ISSN 1475-2875, 09/2019, Volume 18, Issue 1, pp. 1 - 7
Background Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high even among... 
INFECTIOUS DISEASES | ITN | Efficacy | BEDNETS | TROPICAL MEDICINE | MALARIA TRANSMISSION | DURABILITY | IMPACT | LASTING INSECTICIDAL NETS | Malawi | BED NETS | LLINS | Malaria control | PARASITOLOGY | Plasmodium falciparum | Medical research | Care and treatment | Malaria | Patient outcomes | Medicine, Experimental | Research
Journal Article
by Jiang, Xia and Finucane, Hilary K and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Han, Younghun and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Antoniou, Antonis C and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Arun, Banu K and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benlloch, Sara and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brook, Mark N and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caligo, Maria A and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chen, Chu and Christiani, David C and Claes, Kathleen B. M and Claessens, Frank and Clements, Judith and Collée, J. Margriet and Correa, Marcia Cruz and Couch, Fergus J and Cox, Angela and Cunningham, Julie M and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and deFazio, Anna and Devilee, Peter and Diez, Orland and Gago-Dominguez, Manuela and Donovan, Jenny L and Dörk, Thilo and Duell, Eric J and Dunning, Alison M and Dwek, Miriam and Eccles, Diana M and Edlund, Christopher K and Edwards, Digna R. Velez and Ellberg, Carolina and Evans, D. Gareth and Fasching, Peter A and Ferris, Robert L and Liloglou, Triantafillos and Figueiredo, Jane C and Fletcher, Olivia and Fortner, Renée T and Fostira, Florentia and Franceschi, Silvia and Friedman, Eitan and Gallinger, Steven J and Ganz, Patricia A and ...
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 8
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Heritability
Journal Article
by Kupers, LK and Monnereau, C and Sharp, GC and Yousefi, P and Salas, LA and Ghantous, A and Page, CM and Reese, SE and Wilcox, AJ and Czamara, D and Starling, AP and Novoloaca, A and Lent, S and Roy, R and Hoyo, C and Breton, CV and Allard, C and Just, AC and Bakulski, KM and Holloway, JW and Everson, TM and Xu, CJ and Huang, RC and van der Plaat, DA and Wielscher, M and Merid, SK and Ullemar, V and Rezwan, FI and Lahti, J and van Dongen, J and Langie, SAS and Richardson, TG and Magnus, MC and Nohr, EA and Xu, ZL and Duijts, L and Zhao, SS and Zhang, WM and Plusquin, M and DeMeo, DL and Solomon, O and Heimovaara, JH and Jima, DD and Gao, L and Bustamante, M and Perron, P and Wright, RO and Hertz-Picciotto, I and Zhang, HM and Karagas, MR and Gehring, U and Marsit, CJ and Beilin, LJ and Vonk, JM and Jarvelin, MR and Bergstrom, A and Ortqvist, AK and Ewart, S and Villa, PM and Moore, SE and Willemsen, G and Standaert, ARL and Haberg, SE and Sorensen, TIA and Taylor, JA and Raikkonen, K and Yang, IV and Kechris, K and Nawrot, TS and Silver, MJ and Gong, YY and Richiardi, L and Kogevinas, M and Litonjua, AA and Eskenazi, B and Huen, K and Mbarek, H and Maguire, RL and Dwyer, T and Vrijheid, M and Bouchard, L and Baccarelli, AA and Croen, LA and Karmaus, W and Anderson, D and de Vries, M and Sebert, S and Kere, J and Karlsson, R and Arshad, SH and Hamalainen, E and Routledge, MN and Boomsma, DI and Feinberg, AP and Newschaffer, CJ and Govarts, E and Moisse, M and Fallin, MD and Melen, E and Prentice, AM and ...
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1893 - 11
Journal Article