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Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
Journal Article
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
Journal Article
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
Journal Article
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, p. e31-e32
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A13186 - A13186
IntroductionHypertension (HTN) and related disorders constitute a major public-health burden. While genome-wide association studies have identified common... 
Journal Article
Journal of Diabetes and Its Complications, ISSN 1056-8727, 02/2019, Volume 33, Issue 2, p. 118
The TG/HDL-C ratio is used as a marker of insulin resistance (IR) in Caucasians; however, there is limited data in other ethnic groups. We hypothesized that... 
Journal Article
ISSN 1932-6203, 2017
In whites, the minor G allele of the atrial natriuretic peptide (ANP) genetic variant rs5068 is associated with higher circulating levels of ANP and B-type... 
Atrial natriuretic peptides | Atherosclerosis | African Americans | Genetics
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2015, Volume 11, Issue 8
  Genome wide association studies (GWAS) have revealed 11 independent risk loci for polycystic ovary syndrome (PCOS), a common disorder in young women... 
Obesity | Polycystic ovary syndrome | Insulin resistance | Gene loci | Womens health | Insulin
Journal Article
Journal Article
by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene ( ) lower plasma low-density lipoprotein cholesterol... 
DENSITY-LIPOPROTEIN CHOLESTEROL | FACTOR ACETYLHYDROLASES | PROTEIN | LDL | GENETICS & HEREDITY | PCSK9 | PLATELET-ACTIVATING-FACTOR | TRAITS | Genetic Code | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Male | Genetic Variation | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Adult | Cholesterol, LDL - blood | Female | Subtilisins - metabolism | African Continental Ancestry Group - genetics | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Association Studies | Gene Frequency | Mice, Inbred C57BL | Linear Models | Cholesterol, HDL - genetics | Sequence Analysis, DNA | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Cholesterol, LDL - genetics | Phenotype | Animals | Coronary Disease - genetics | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Subtilisins - genetics | Aged | Mice | Cohort Studies | Genetic code | Genetic variation | Physiological aspects | Genetic research | Genetic aspects | Research | Coronary heart disease | Population genetics | Lipids | Cardiovascular disease | Low density lipoprotein | Risk assessment | Deoxyribonucleic acid--DNA | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Jostins, Luke and Ripke, Stephan and Weersma, Rinse K and Duerr, Richard H and McGovern, Dermot P and Hui, Ken Y and Lee, James C and Schumm, L. Philip and Sharma, Yashoda and Anderson, Carl A and Essers, Jonah and Mitrovic, Mitja and Ning, Kaida and Cleynen, Isabelle and Theatre, Emilie and Spain, Sarah L and Raychaudhuri, Soumya and Goyette, Philippe and Wei, Zhi and Abraham, Clara and Achkar, Jean-Paul and Ahmad, Tariq and Amininejad, Leila and Ananthakrishnan, Ashwin N and Andersen, Vibeke and Anews, Jane M and Baidoo, Leonard and Balschun, Tobias and Bampton, Peter A and Bitton, Alain and Boucher, Gabrielle and Brand, Stephan and Büning, Carsten and Cohain, Ariella and Cichon, Sven and D'Amato, Mauro and de Jong, Dirk and Devaney, Kathy L and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Ferguson, Lynnette R and Franchimont, Denis and Fransen, Karin and Gearry, Richard and Georges, Michel and Gieger, Christian and Glas, Jürgen and Haritunians, Talin and Hart, Ailsa and Hawkey, Chris and Hedl, Matija and Hu, Xinli and Karlsen, Tom H and Kupcinskas, Limas and Kugathasan, Subra and Latiano, Anna and Laukens, Debby and Lawrance, Ian C and Lees, Charlie W and Louis, Edouard and Mahy, Gillian and Mansfield, John and Morgan, Angharad R and Mowat, Craig and Newman, William and Palmieri, Orazio and Ponsioen, Cyriel Y and Potocnik, Uros and Prescott, Natalie J and Regueiro, Miguel and Rotter, Jerome I and Russell, Richard K and Sanderson, Jeremy D and Sans, Miquel and Satsangi, Jack and Schreiber, Stefan and Simms, Lisa A and Sventoraityte, Jurgita and Targan, Stephan R and Taylor, Kent D and Tremelling, Mark and Verspaget, Hein W and de Vos, Martine and Wijmenga, Cisca and Wilson, David C and Winkelmann, Juliane and Xavier, Ramnik J and Zeissig, Sebastian and Zhang, Bin and Zhang, Clarence K and Zhao, Hongyu and Silverberg, Mark S and Annese, Vito and Hakonarson, Hakon and Brant, Steven R and Radford-Smith, Graham and Mathew, Christopher G and Rioux, John D and Schadt, Eric E and ... and Int IBD Genetics Consortium IIBDGC and International IBD Genetics Consortium (IIBDGC) and The International IBD Genetics Consortium (IIBDGC) and Region Örebro län and Örebro universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2012, Volume 491, Issue 7422, pp. 119 - 124
Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with... 
HYPER-IGE SYNDROME | RISK LOCI | NETWORK | NUMBER | METAANALYSIS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | MUTATIONS | EXPRESSION | Crohn Disease - genetics | Humans | Inflammatory Bowel Diseases - immunology | Colitis, Ulcerative - genetics | Mycobacterium tuberculosis - immunology | Inflammatory Bowel Diseases - physiopathology | Colitis, Ulcerative - immunology | Host-Pathogen Interactions - immunology | Mycobacterium tuberculosis - pathogenicity | Haplotypes - genetics | Mycobacterium - pathogenicity | Mycobacterium Infections - genetics | Inflammatory Bowel Diseases - genetics | Crohn Disease - microbiology | Mycobacterium Infections - microbiology | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Reproducibility of Results | Mycobacterium - immunology | Crohn Disease - immunology | Genome, Human - genetics | Phenotype | Colitis, Ulcerative - microbiology | Host-Pathogen Interactions - genetics | Polymorphism, Single Nucleotide - genetics | Inflammatory Bowel Diseases - microbiology | Crohn Disease - physiopathology | Colitis, Ulcerative - physiopathology | Inflammatory bowel disease | Candidates | Tuberculosis | Architecture | Genetics | Genomes | Diabetes | Gene expression | Health risk assessment | Immune system | Index Medicus | Rheumatology and Autoimmunity | Basic Medicine | Medical Genetics | Medicinsk genetik | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin
Journal Article
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6086, pp. 1314 - 1317
The intestinal microflora, typically equated with bacteria, influences diseases such as obesity and inflammatory bowel disease. Here, we show that the... 
Fungi | Haplotypes | Microorganisms | Inflammatory bowel diseases | Commensals | REPORTS | Bacteria | Mice | Colitis | Intestinal diseases | Ulcerative colitis | RESPONSES | INFECTIONS | CANDIDA-ALBICANS | RECOGNITION | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | SUSCEPTIBILITY | INFLAMMASOME | GUT MICROBIOTA | INDUCTION | GENOME-WIDE ASSOCIATION | Dextran Sulfate | Fungi - classification | Candida tropicalis - isolation & purification | Humans | Immunity, Mucosal | Fungi - isolation & purification | Colon - immunology | Colony Count, Microbial | Candida tropicalis - physiology | Lectins, C-Type - genetics | Colitis, Ulcerative - immunology | Intestines - immunology | Fungi - immunology | Lectins, C-Type - metabolism | Intestinal Mucosa - immunology | Fungi - physiology | Female | Lectins, C-Type - deficiency | Disease Susceptibility | Mice, Inbred C57BL | Candida tropicalis - pathogenicity | Antibodies, Fungal - blood | Intestinal Mucosa - microbiology | Immunity, Innate | Animals | Intestines - microbiology | Colitis, Ulcerative - microbiology | Colitis, Ulcerative - chemically induced | Candida tropicalis - immunology | Colon - microbiology | Polymorphism, Single Nucleotide | Metagenome | Microbiota (Symbiotic organisms) | Causes of | Physiological aspects | Lectins | Development and progression | Genetic aspects | Inflammatory bowel disease | Digestive system | Immune system | Index Medicus | Pathology | Health | Deletion | Mammals | Inhabitants
Journal Article