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in vitro techniques (12) 12
animals (11) 11
humans (9) 9
respiratory system (9) 9
cattle (7) 7
muscle, smooth - physiology (7) 7
index medicus (6) 6
isoprostanes - pharmacology (6) 6
muscle, smooth - drug effects (6) 6
contraction (5) 5
muscle, smooth, vascular - drug effects (5) 5
asthma (4) 4
biochemistry & molecular biology (4) 4
bronchi - physiology (4) 4
calcium (4) 4
cell biology (4) 4
dose-response relationship, drug (4) 4
lipid-peroxidation (4) 4
muscle relaxation - drug effects (4) 4
oxidative stress (4) 4
pharmacology & pharmacy (4) 4
physiology (4) 4
potassium chloride - pharmacology (4) 4
research (4) 4
smooth muscle (4) 4
trachea - drug effects (4) 4
trachea - physiology (4) 4
vasoconstriction - drug effects (4) 4
abridged index medicus (3) 3
airway smooth muscle (3) 3
amides - pharmacology (3) 3
bronchi - drug effects (3) 3
carbachol - pharmacology (3) 3
cardiac & cardiovascular systems (3) 3
cells (3) 3
dinoprostone - pharmacology (3) 3
enzyme inhibitors - pharmacology (3) 3
genistein - pharmacology (3) 3
indoles - pharmacology (3) 3
muscle contraction - drug effects (3) 3
oxidant stress (3) 3
pulmonary artery - drug effects (3) 3
pyridines - pharmacology (3) 3
rho-associated kinases (3) 3
signal transduction (3) 3
vasoconstriction - physiology (3) 3
vasoconstrictor agents - pharmacology (3) 3
8-epi-prostaglandin f2-alpha (2) 2
8-iso-prostaglandin e-2 (2) 2
acetylcholine - pharmacology (2) 2
actins - metabolism (2) 2
activation (2) 2
adult (2) 2
aged (2) 2
artery (2) 2
bronchial hyperreactivity - physiopathology (2) 2
bronchial thermoplasty (2) 2
caffeine (2) 2
caffeine - pharmacology (2) 2
calcium - metabolism (2) 2
calcium - physiology (2) 2
calcium-transporting atpases - metabolism (2) 2
canine (2) 2
chromatography-mass-spectrometry (2) 2
clinical trials (2) 2
coronary artery bypass (2) 2
coronary-artery (2) 2
cystic-fibrosis (2) 2
diabetes (2) 2
dinoprost - analogs & derivatives (2) 2
dinoprost - pharmacology (2) 2
dinoprostone - analogs & derivatives (2) 2
exhaled breath condensate (2) 2
female (2) 2
glucose (2) 2
glycemic control (2) 2
health aspects (2) 2
hyperglycemia (2) 2
hypertension (2) 2
hypoglycemia (2) 2
in-vivo (2) 2
inhibition (2) 2
insulin (2) 2
intracellular signaling peptides and proteins (2) 2
isometric contraction - drug effects (2) 2
isoproterenol - pharmacology (2) 2
k+ current (2) 2
kinases (2) 2
lung - drug effects (2) 2
lung - physiology (2) 2
mechanisms (2) 2
medicine, general & internal (2) 2
middle aged (2) 2
muscle contraction - physiology (2) 2
muscle relaxation - physiology (2) 2
muscle, smooth, vascular - physiology (2) 2
myosin light chain phosphatase (2) 2
myosin phosphatase (2) 2
myosin-light-chain kinase - metabolism (2) 2
patch-clamp techniques (2) 2
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1. Full Text Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial
by Feig, Denice S and Donovan, Lois E and Corcoy, Rosa and Murphy, Helen R and Murphy, Kellie E and Amiel, Stephanie A and Hunt, Katharine F and Asztalos, Elizabeth and Barrett, Jon F R and Sanchez, J Johanna and de Leiva, Alberto and Hod, Moshe and Jovanovic, Lois and Keely, Erin and McManus, Ruth and Hutton, Eileen K and Meek, Claire L and Stewart, Zoe A and Wysocki, Tim and O'Brien, Robert and Ruedy, Katrina and Kollman, Craig and Tomlinson, George and Grisoni, Jeannie and Byrne, Carolyn and Davenport, Katy and Neoh, Sandra and Gougeon, Claire and Oldford, Carolyn and Young, Catherine and Green, Louisa and Rossi, Benedetta and Rogers, Helen and Cleave, Barbara and Strom, Michelle and Adelantado, Juan María and Isabel Chico, Ana and Tundidor, Diana and Malcolm, Janine and Henry, Kathy and Morris, Damian and Morris, Juliet and Rayman, Gerry and Fowler, Duncan and Mitchell, Susan and Rosier, Josephine and Temple, Rosemary and Turner, Jeremy and Canciani, Gioia and Hewapathirana, Niranjala and Piper, Leanne and Kudirka, Anne and Watson, Margaret and Bonomo, Matteo and Pintaudi, Basilio and Bertuzzi, Federico and Daniela, Giuseppina and Mion, Elena and Lowe, Julia and Halperin, Ilana and Rogowsky, Anna and Adib, Sapida and Lindsay, Robert and Carty, David and Crawford, Isobel and Mackenzie, Fiona and McSorley, Therese and Booth, John and McInnes, Natalia and Smith, Ada and Stanton, Irene and Tazzeo, Tracy and Weisnagel, John and Mansell, Peter and Jones, Nia and Babington, Gayna and Spick, Dawn and MacDougall, Malcolm and Chilton, Sharon and Cutts, Terri and Perkins, Michelle and Scott, Eleanor and Endersby, Del and Dover, Anna and Dougherty, Frances and Johnston, Susan and Heller, Simon and Novodorsky, Peter and Hudson, Sue and Nisbet, Chloe and Ransom, Thomas and Coolen, Jill and Baxendale, Darlene and Holt, Richard and Forbes, Jane and Martin, Nicki and Walbridge, Fiona and Dunne, Fidelma and Conway, Sharon and Egan, Aoife and ... and CONCEPTT Collaborative Grp and CONCEPTT Collaborative Group
The Lancet, ISSN 0140-6736, 11/2017, Volume 390, Issue 10110, pp. 2347 - 2359
Pregnant women with type 1 diabetes are a high-risk population who are recommended to strive for optimal glucose control, but neonatal outcomes attributed to... 
HYPOGLYCEMIA | VALIDATION | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | CLINICAL-TRIAL | Women | Blood sugar monitoring | Pregnant women | Type 1 diabetes | Patient monitoring equipment | Glucose | Health aspects | Dextrose | Diabetes therapy | Pregnancy | Studies | Medical research | Womens health | Diabetes mellitus | Clinical trials | Neonates | Therapy | Intensive care | Diabetes mellitus (insulin dependent) | Gestation | Gestational age | Randomization | Hyperglycemia | Newborn babies | Vomiting | Hemoglobin | Monitoring | Age | Risk groups | Health | Health risks | Nausea | Hypoglycemia | Insulin | Obstetrics | Preeclampsia | Skin | Diabetes
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2. Full Text Caffeine relaxes smooth muscle through actin depolymerization
by Tazzeo, Tracy and Bates, Genevieve and Roman, Horia Nicolae and Lauzon, Anne-Marie and Khasnis, Mukta D and Eto, Masumi and Janssen, Luke J
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 08/2012, Volume 303, Issue 4, pp. L334 - L342
Tazzeo T, Bates G, Roman HN, Lauzon A, Khasnis MD, Eto M, Janssen LJ. Caffeine relaxes smooth muscle through actin depolymerization. Am J Physiol Lung Cell Mol... 
Ryanodine | handling | Excitation-contraction coupling | Airway smooth muscle | Asthma | PHYSIOLOGY | REVERSE-MODE | Ca2+ handling | airway smooth muscle | asthma | CA2+ STORE | TRACHEAL MYOCYTES | SIGNAL-TRANSDUCTION | CYCLOPIAZONIC ACID | PHOSPHODIESTERASE INHIBITORS | ryanodine | CONTRACTION | RESPIRATORY SYSTEM | CALCIUM | excitation-contraction coupling | MYOSIN PHOSPHATASE | ACTIVATES CL | Biopolymers - chemistry | Permeability - drug effects | Phosphoric Diester Hydrolases - metabolism | Myosin-Light-Chain Kinase - metabolism | Humans | Actins - metabolism | Phosphodiesterase Inhibitors - pharmacology | Enzyme Assays | Biopolymers - metabolism | Muscle, Smooth - drug effects | Polymerization - drug effects | Animals | Cattle | Muscle Contraction - drug effects | Muscle Contraction - physiology | Potassium Chloride - pharmacology | Caffeine - pharmacology | Theophylline - pharmacology | Indoles - pharmacology | Muscle, Smooth - physiology | Muscle Relaxation - drug effects | In Vitro Techniques | Muscle, Smooth - enzymology | Smooth muscle | Research | Actin | Caffeine
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3. Full Text Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction
by Dyrda, Peter and Tazzeo, Tracy and DoHarris, Lindsay and Nilius, Berndt and Roman, Horia Nicolae and Lauzon, Anne-Marie and Aziz, Tariq and Lukic, Dusan and Janssen, Luke J
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 02/2011, Volume 44, Issue 2, pp. 213 - 221
Despite the emerging use of bronchial thermoplasty in asthma therapy, the response of airway smooth muscle (ASM) to extreme temperatures is unknown. We... 
Airway smooth muscle | TRPV channels | Thermoplasty | Myosin | Asthma | CELLS | 2-AMINOETHOXYDIPHENYL BORATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIGHT-CHAIN | airway smooth muscle | myosin | REVERSIBLE PHOSPHORYLATION | TRPV2 | asthma | BRONCHIAL THERMOPLASTY | CAPSAICIN-RECEPTOR | CELL BIOLOGY | CATION CHANNELS | SMOOTH-MUSCLE | RESPIRATORY SYSTEM | HIGH-THRESHOLD | thermoplasty | Hot Temperature - adverse effects | Acetylcholine - pharmacology | Isometric Contraction - drug effects | Myosin-Light-Chain Kinase - metabolism | Actins - metabolism | Trachea - drug effects | Bronchi - drug effects | Trachea - pathology | Muscle, Smooth - drug effects | TRPV Cation Channels - metabolism | Animals | Cattle | Isoproterenol - pharmacology | Protein Denaturation | Trachea - physiology | Muscle, Smooth - physiology | Myosins - metabolism | Bronchi - physiology | In Vitro Techniques | Isometric Contraction - physiology | Trachea - injuries
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4. Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature
by Janssen, Luke J and Tazzeo, Tracy
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2002, Volume 301, Issue 3, pp. 1060 - 1066
Although isoprostanes generally act on smooth muscle via TXA(2)-selective prostanoid receptors (TPs), some suggest other prostanoid receptors or possibly even... 
PROSTANOID RECEPTORS | RAT | 8-ISO-PGF(2-ALPHA) | 8-ISO PROSTAGLANDIN-F2-ALPHA | PHARMACOLOGY & PHARMACY | ANGIOTENSIN-II | ENDOTHELIN-1 | ARTERY | HYPERTENSION | SMOOTH-MUSCLE CELLS | F2-ISOPROSTANE | Pulmonary Veins - drug effects | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Swine | Pulmonary Veins - physiology | Receptors, Thromboxane - antagonists & inhibitors | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | Isoprostanes - physiology | Pulmonary Artery - drug effects | Lung - physiology | Receptors, Prostaglandin E, EP3 Subtype | Vasoconstriction - drug effects | Pulmonary Artery - physiology | Receptors, Prostaglandin E - physiology | Animals | Isoprostanes - pharmacology | Receptors, Prostaglandin E - agonists | Receptors, Thromboxane - agonists | Lung - drug effects | Receptors, Prostaglandin E - antagonists & inhibitors | Dinoprostone - analogs & derivatives | Receptors, Thromboxane - physiology | In Vitro Techniques | Lung - blood supply
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5. Full Text KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase
by Luke J. Janssen and Tracy Tazzeo and Jianmin Zuo and Evi Pertens and Shaf Keshavjee
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 10/2004, Volume 287, Issue 4, pp. 852 - 858
Airway smooth muscle (ASM) cells express voltage-dependent Ca2+ channels, primarily of the L-subtype. These may play a role in excitation-contraction coupling... 
CELLS | PHYSIOLOGY | PROTEIN-KINASE | PHOSPHATASE | myosin light chain phosphatase | MECHANISMS | voltage-dependent calcium channels | T-TYPE | HYPERRESPONSIVENESS | Rho-associated kinase | INHIBITION | NONMUSCLE MYOSIN-II | RESPIRATORY SYSTEM | PORCINE TRACHEAL | Rho | MEDIATED CA2+ SENSITIZATION | Amides - pharmacology | Respiratory Mucosa - drug effects | Humans | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | rhoA GTP-Binding Protein - metabolism | Bronchi - drug effects | Muscle, Smooth - drug effects | Calcium - physiology | Potassium Chloride - pharmacology | rho-Associated Kinases | Muscle, Smooth - physiology | Respiratory Mucosa - physiology | Bronchi - physiology | Pyridines - pharmacology | In Vitro Techniques | Protein-Serine-Threonine Kinases - metabolism
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6. Full Text Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling
by Caiqiong Liu and Tracy Tazzeo and Luke J. Janssen
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, pp. 1177 - 1184
We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR). In this study, we examined the signaling mechanisms underlying... 
Cholinergic responsiveness | Relaxation | Rho kinase | Sarcoplasmic reticulum | Airway smooth muscle | Contraction | RhoA | OXIDATIVE STRESS | PHYSIOLOGY | LIPID-PEROXIDATION | 8-EPI-PROSTAGLANDIN F2-ALPHA | relaxation | EXHALED 8-ISOPROSTANE | airway smooth muscle | sarcoplasmic reticulum | CHROMATOGRAPHY-MASS-SPECTROMETRY | RESPIRATORY SYSTEM | cholinergic responsiveness | EXPIRED BREATH CONDENSATE | IN-VIVO | contraction | SMOOTH-MUSCLE-CELLS | CALCIUM MOBILIZATION | CYSTIC-FIBROSIS | Amides - pharmacology | Dinoprostone - pharmacology | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Enzyme Inhibitors - pharmacology | Respiratory System | Carbachol - pharmacology | Muscle, Smooth - drug effects | Animals | Calcium - physiology | Isoprostanes - pharmacology | Cattle | Bronchial Hyperreactivity - physiopathology | rho-Associated Kinases | Trachea - physiology | Muscle, Smooth - physiology | Pyridines - pharmacology | In Vitro Techniques | Intracellular Signaling Peptides and Proteins - physiology
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7. Full Text KC1 evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase
by Janssen, Luke J and Tazzeo, Tracy and Zuo, Jianmin and Pertens, Evi and Keshavjee, Shaf
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 10/2004, Volume 287, Issue 4, pp. L852 - L858
Rho | Voltage-dependent calcium channels | Myosin light chain phosphatase | Rho-associated kinase
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8. Full Text E-Ring Isoprostane Augments Cholinergic Neurotransmission in Bovine Trachealis via FP Prostanoid Receptors
by Paredes, Christine and Tazzeo, Tracy and Janssen, Luke J
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 12/2007, Volume 37, Issue 6, pp. 739 - 747
Isoprostanes are prostaglandin-like molecules that accumulate in oxidative stress and also exert powerful biological effects on a wide variety of tissues. We... 
Isoprostane | Oxidative stress | Prostanoid receptor | Cholinergic neurotransmission | EXHALED BREATH CONDENSATE | VASOCONSTRICTOR RESPONSES | LIPID-PEROXIDATION | K+ CURRENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | 8-ISO-PROSTAGLANDIN E-2 | cholinergic neurotransmission | CELL BIOLOGY | SIGNALING PATHWAY | RESPIRATORY SYSTEM | ENDOTHELIAL-CELLS | isoprostane | PARASYMPATHETIC NERVES | oxidative stress | PROSTAGLANDIN E-2 | prostanoid receptor | Choline - metabolism | Trachea - cytology | Acetylcholine - pharmacology | Trachea - drug effects | Trachea - metabolism | Receptors, Prostaglandin - metabolism | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Animals | Receptors, Prostaglandin - agonists | Isoprostanes - pharmacology | Cattle | Muscle Contraction - drug effects | Receptors, Thromboxane - agonists | Receptors, Thromboxane - antagonists & inhibitors | Molecular Mimicry - drug effects | Synaptic Transmission - drug effects | Neurons - metabolism | Muscle Relaxation - drug effects | Muscle, Smooth - cytology | In Vitro Techniques | Neurons - drug effects | Receptors, Prostaglandin - antagonists & inhibitors
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9. Full Text Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle
by Tazzeo, Tracy and Miller, John and Janssen, Luke J
British Journal of Pharmacology, ISSN 0007-1188, 10/2003, Volume 140, Issue 4, pp. 759 - 763
We investigated the effects of five different isoprostanes (8‐iso PGE1, 8‐iso PGE2, 8‐iso PGF1α, 8‐iso PGF2α and 8‐iso PGF2β) on vasomotor tone in human and... 
Prostanoid receptors | free radicals | pulmonary hypertension | oxidative stress | reactive oxygen species | Oxidative stress | Reactive oxygen species | Free radicals | Pulmonary hypertension | CONDENSATE | LIPID-PEROXIDATION | OXIDANT STRESS | RHO-KINASE | REPERFUSION | ANGIOTENSIN | prostanoid receptors | PHARMACOLOGY & PHARMACY | HYPERTENSION | CANINE | Humans | Prostaglandins E - pharmacology | Alprostadil - analogs & derivatives | Bronchial Arteries - physiology | Receptors, Thromboxane A2, Prostaglandin H2 - physiology | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Bronchial Arteries - drug effects | Swine | Receptors, Thromboxane A2, Prostaglandin H2 - drug effects | Dinoprost - analogs & derivatives | Dioxanes - pharmacology | Dinoprost - pharmacology | Muscle, Smooth, Vascular - drug effects | Amides - pharmacology | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | F2-Isoprostanes - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | Alprostadil - pharmacology | Vasoconstriction - drug effects | Isoprostanes - antagonists & inhibitors | Animals | Isoprostanes - pharmacology | Signal Transduction - drug effects | Genistein - pharmacology | Dinoprostone - analogs & derivatives | Prostaglandins F, Synthetic - pharmacology | Signal Transduction - physiology | Pyridines - pharmacology | Dinoprostone - antagonists & inhibitors | Papers
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10. Caffeine relaxes smooth muscle through actin depolymerization
by Tracy Tazzeo and Genevieve Bates and Horia Nicolae Roman and Anne-Marie Lauzon and Mukta D Khasnis and Masumi Eto and Luke J Janssen
American Journal of Physiology, ISSN 1040-0605, 08/2012, Volume 303, Issue 4, p. L334
  Caffeine is sometimes used in cell physiological studies to release internally stored ... We obtained evidence that caffeine may also act through a different... 
Phosphorylation | Calcium | Kinases | Cells | Binding sites | Caffeine
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11. Full Text Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation
by Mueed, Irem, PhD and Tazzeo, Tracy, BSc and Liu, Ciaqiong, BSc and Pertens, Evi, BSc and Zhang, Yongde, PhD and Cybulski, Irene, MD and Semelhago, Lloyd, MD and Noora, Joseph, MD and Lamy, Andre, MD and Teoh, Kevin, MD and Chu, Victor, MD and Janssen, Luke J., PhD
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2008, Volume 135, Issue 1, pp. 131 - 138
Objectives Radial artery vasospasm remains a potential cause of early graft failure after coronary bypass graft surgery, despite pretreatment with α-adrenergic... 
Cardiothoracic Surgery | SURGERY | REVASCULARIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | CORONARY-BYPASS SURGERY | KINASE | PHENOXYBENZAMINE | 8-ISO-PROSTAGLANDIN E-2 | SMOOTH-MUSCLE | PRETREATMENT | RESPIRATORY SYSTEM | INTERNAL MAMMARY | MYOSIN PHOSPHATASE | Vasoconstrictor Agents - pharmacology | Signal Transduction | Calcium - metabolism | Humans | rhoA GTP-Binding Protein - metabolism | Vasoconstriction - drug effects | Receptors, Thromboxane A2, Prostaglandin H2 | Radial Artery - physiopathology | Isoprostanes - pharmacology | Receptors, Thromboxane - drug effects | Tissue and Organ Harvesting | Radial Artery - drug effects | In Vitro Techniques
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12. Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca super(2+) handling and Rho/ROCK signaling
by Liu, Caiqiong and Tazzeo, Tracy and Janssen, Luke J
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, pp. L1177 - L1184
We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR). In this study, we examined the signaling mechanisms underlying... 
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13. Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling
by Caiqiong Liu and Tracy Tazzeo and Luke J Janssen
American Journal of Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, p. L1177
  We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR). In this study, we examined the signaling mechanisms underlying... 
Studies | Signal transduction | Airway management | Protease inhibitors | Respiratory diseases | Kinases | Asthma
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14. Full Text Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles
by Luke J. Janssen and Jennifer Wattie and Hwa Lu-Chao and Tracy Tazzeo
Journal of Applied Physiology, ISSN 8750-7587, 09/2001, Volume 91, Issue 3, pp. 1142 - 1151
We investigated the mechanisms underlying muscarinic excitation-contraction coupling in canine airway smooth muscle using organ bath, fura 2 fluorimetric, and... 
Calcium ion-dependent chlorine ion current | Tyrosine kinase | Airway smooth muscle contraction | Rho kinase | Genistein | Phosphatidylinositol 3-kinase | Calcium ion-adenosinetriphosphatase | Airway hyperresponsiveness | airway hyperresponsiveness | SPORT SCIENCES | PHYSIOLOGY | CA2+ STORES | DISTINCT PATHWAYS | calcium ion-adenosinetriphosphatase | AIRWAY MYOCYTES | tyrosine kinase | calcium ion-dependent chlorine ion current | airway smooth muscle contraction | CURRENTS | CYTOSOLIC CALCIUM | SWINE TRACHEALIS | SIGNAL-TRANSDUCTION | genistein | ACETYLCHOLINE-INDUCED CONTRACTIONS | RECEPTORS | CANINE | phosphatidylinositol 3-kinase | Calcium-Transporting ATPases - antagonists & inhibitors | Calcium - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Sarcoplasmic Reticulum - enzymology | Muscle Relaxation - physiology | Bronchial Hyperreactivity - physiopathology | Chlorides - metabolism | rho-Associated Kinases | Trachea - physiology | Calcium-Transporting ATPases - metabolism | Indoles - pharmacology | Muscle, Smooth - physiology | Bronchi - physiology | Cholinergic Agonists - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Sarcoplasmic Reticulum Calcium-Transporting ATPases | Carbachol - pharmacology | Patch-Clamp Techniques | Animals | Muscle Contraction - drug effects | Muscle Contraction - physiology | Dogs | Genistein - pharmacology | Muscle Relaxation - drug effects | Receptors, Muscarinic - physiology
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15. Full Text Enhanced Myosin Phosphatase and Ca2+-Uptake Mediate Adrenergic Relaxation of Airway Smooth Muscle
by Janssen, Luke J and Tazzeo, Tracy and Zuo, Jianmin
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2004, Volume 30, Issue 4, pp. 548 - 554
We examined the mechanisms underlying relaxations evoked by isoproterenol (Iso) in isolated porcine, bovine, or human tracheal and bronchial tissues (TSM and... 
CALCIUM-CHANNEL BLOCKER | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | TRACHEAL MYOCYTES | CELL BIOLOGY | BRL-38227 | ACTIVATOR | CONTRACTION | CA2 | RESPIRATORY SYSTEM | NIFEDIPINE | ASTHMA
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16. Full Text Reduction of arterial graft smooth muscle mass by moderate heat therapy
by Mueed, Irem and Tazzeo, Tracy and Doharris, Lindsay and Aziz, Tariq and Chu, Victor and Janssen, Luke J
Translational Research, ISSN 1931-5244, 2011, Volume 157, Issue 3, pp. 128 - 138
Radial artery (RA) graft spasm is a major cause of early graft failure in coronary artery bypass grafting surgeries. We explored the feasibility of thermal... 
Internal Medicine | MEDICINE, RESEARCH & EXPERIMENTAL | FOLLOW-UP | BYPASS-SURGERY | TRANSURETHRAL MICROWAVE THERMOTHERAPY | CORONARY-ARTERY | BRONCHIAL THERMOPLASTY | MEDICINE, GENERAL & INTERNAL | ANGIOPLASTY | RADIOFREQUENCY THERMAL BALLOON | MEDICAL LABORATORY TECHNOLOGY | IN-VITRO VASOREACTIVITY | HUMAN RADIAL ARTERY | PATENCY | Radial Artery - anatomy & histology | Humans | Middle Aged | Postoperative Complications - prevention & control | Femoral Artery - anatomy & histology | Radio Waves - therapeutic use | Radial Artery - transplantation | Coronary Vasospasm - prevention & control | Models, Animal | Femoral Artery - transplantation | Radial Artery - physiology | Muscle, Smooth, Vascular - physiology | Hot Temperature - therapeutic use | Rabbits | Coronary Artery Bypass - methods | Vasoconstriction | Rats | Coronary Artery Bypass - adverse effects | Animals | Perfusion | Muscle, Smooth, Vascular - anatomy & histology | Aged | Femoral Artery - physiology | In Vitro Techniques | Vascular Patency | Coronary artery bypass | Transplantation of organs, tissues, etc | Analysis
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17. Full Text CONCEPTT: Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial: A multi-center, multi-national, randomized controlled trial - Study protocol
by Feig, Denice S and Asztalos, Elizabeth and Corcoy, Rosa and De Leiva, Alberto and Donovan, Lois and Hod, Moshe and Jovanovic, Lois and Keely, Erin and Kollman, Craig and McManus, Ruth and Murphy, Kellie and Ruedy, Katrina and Sanchez, J.Johanna and Tomlinson, George and Murphy, Helen R and Feig, Denice and Cleave, Barbara and Donat, Diane and Gandhi, Shital and Strom, Michelle and Chico, Ana Isabel and José Martínez, M and Sánchez, Mireia and Tundidor, Diana and Amiel, Stephanie and Hunt, Katharine and Green, Louisa and Rogers, Helen and Rossi, Benedetta and Stodhart, Ben and Bonomo, Matteo and Bertuzzi, Federico and Corica, Giuseppina D and Fazio, Silvana and Giro, Roberto and Mion, Elena and Moletta, Andrea and Pintaudi, Basilio and Sorrentino, Rosa and Booth, John and McInnes, Natalia and Nykamp, Adelle and Otto, Rose and Smith, Ada and Stanton, Irene and Tazzeo, Tracy and Oldford, Carolyn and Young, Catherine and Gougeon, Claire and Houlden, Robyn and Breen, Adriana and Castorino, Kristin and Sansum, William and Erin Keely, Keely and Clark, Heather and Gaudet, Laura and Karovitch, Alan and Malcolm, Janine and Lowe, Julia and Rogowsky, Anna and Kudirka, Anne and Watson, Margaret and Morris, Damian and Farnworth, Frances and Fowler, Duncan and Mitchell, Sue and Rosier, Josephine and Murphy, Helen and Byrne, Caroline and Davenport, Katy and Grisoni, Jeannie and Mulrennan, Sandra and Neoh, Sandra and O'Sullivan, Esther and Simmons, David and Stewart, Zoe and Templin, Heike and Helen Murphy, Murphy and Turner, Jeremy and Canciani, Gioia and Hewapathirana, Niranjala and Jones, Louise and Piper, Leanne and Temple, Rosemary and Wallace, Tara and Maitland, Rahat and Banerjee, Anita and Briley, Annette and Brackenridge, Anna and Gilby, Pam and Gill, Carolyn and Reid, Anna and Singh, Claire and White, Sara and Wolfs, Maria and Scott, Eleanor and Endersby, Del and Maresh, Michael and Kearney, Gretta and Morris, Juliet and ... and CONCEPTT Collaborative Grp and CONCEPTT Collaborative Group and on behalf of the CONCEPTT Collaborative Group
BMC Pregnancy and Childbirth, ISSN 1471-2393, 07/2016, Volume 16, Issue 1, p. 167
Background: Women with type 1 diabetes strive for optimal glycemic control before and during pregnancy to avoid adverse obstetric and perinatal outcomes. For... 
Continuous glucose monitoring | Pregnancy | Preconception | Diabetes mellitus type 1 | Randomized controlled trial | GLYCEMIC CONTROL | OBSTETRICS & GYNECOLOGY | Hypoglycemia - diagnosis | Hypoglycemic Agents - therapeutic use | Pregnancy Complications - blood | Monitoring, Ambulatory - methods | Glycated Hemoglobin A - metabolism | Humans | Pregnancy Complications - diagnosis | Diabetes Mellitus, Type 1 - drug therapy | Young Adult | Birth Weight | Diabetes Mellitus, Type 1 - blood | Adolescent | Blood Glucose Self-Monitoring | Adult | Female | Hypoglycemia - blood | Blood Glucose - metabolism | Pregnancy in Diabetics - blood | Research Design | Infant, Newborn | Insulin - therapeutic use | Type 2 diabetes | Complications and side effects | Care and treatment | Usage | Pregnant women | Patient monitoring equipment | Glycosylated hemoglobin | Clinical trials | Research | Health aspects | Hyperglycemia | Systematic review | Glucose | Diabetes | Hypoglycemia | Insulin
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