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life sciences & biomedicine (15) 15
science & technology (15) 15
in vitro techniques (12) 12
animals (11) 11
biological and medical sciences (9) 9
respiratory system (9) 9
humans (8) 8
cattle (7) 7
muscle, smooth - physiology (7) 7
isoprostanes - pharmacology (6) 6
muscle, smooth - drug effects (6) 6
fundamental and applied biological sciences. psychology (5) 5
medical sciences (5) 5
muscle, smooth, vascular - drug effects (5) 5
biochemistry & molecular biology (4) 4
bronchi - physiology (4) 4
cell biology (4) 4
dose-response relationship, drug (4) 4
muscle relaxation - drug effects (4) 4
pharmacology & pharmacy (4) 4
physiology (4) 4
potassium chloride - pharmacology (4) 4
smooth muscle (4) 4
trachea - drug effects (4) 4
trachea - physiology (4) 4
vasoconstriction - drug effects (4) 4
vertebrates: respiratory system (4) 4
airway smooth muscle (3) 3
amides - pharmacology (3) 3
asthma (3) 3
bronchi - drug effects (3) 3
calcium (3) 3
carbachol - pharmacology (3) 3
cardiac & cardiovascular systems (3) 3
cardiovascular system & cardiology (3) 3
contraction (3) 3
dinoprostone - pharmacology (3) 3
enzyme inhibitors - pharmacology (3) 3
genistein - pharmacology (3) 3
indoles - pharmacology (3) 3
muscle contraction - drug effects (3) 3
pulmonary artery - drug effects (3) 3
pyridines - pharmacology (3) 3
research (3) 3
rho-associated kinases (3) 3
vasoconstriction - physiology (3) 3
vasoconstrictor agents - pharmacology (3) 3
abridged index medicus (2) 2
acetylcholine - pharmacology (2) 2
actins - metabolism (2) 2
aged (2) 2
bronchial hyperreactivity - physiopathology (2) 2
caffeine - pharmacology (2) 2
calcium - metabolism (2) 2
calcium - physiology (2) 2
calcium-transporting atpases - metabolism (2) 2
cardiology. vascular system (2) 2
coronary artery bypass (2) 2
dinoprost - analogs & derivatives (2) 2
dinoprost - pharmacology (2) 2
dinoprostone - analogs & derivatives (2) 2
intracellular signaling peptides and proteins (2) 2
isometric contraction - drug effects (2) 2
isoproterenol - pharmacology (2) 2
kinases (2) 2
lung - drug effects (2) 2
lung - physiology (2) 2
middle aged (2) 2
muscle contraction - physiology (2) 2
muscle relaxation - physiology (2) 2
muscle, smooth, vascular - physiology (2) 2
myosin-light-chain kinase - metabolism (2) 2
oxidative stress (2) 2
patch-clamp techniques (2) 2
pneumology (2) 2
protein-serine-threonine kinases - metabolism (2) 2
pulmonary artery - physiology (2) 2
pulmonary veins - drug effects (2) 2
pulmonary veins - physiology (2) 2
receptors, thromboxane - agonists (2) 2
receptors, thromboxane - antagonists & inhibitors (2) 2
relaxation (2) 2
rho kinase (2) 2
rhoa (2) 2
rhoa gtp-binding protein - metabolism (2) 2
sarcoplasmic reticulum (2) 2
sarcoplasmic reticulum calcium-transporting atpases (2) 2
signal transduction (2) 2
swine (2) 2
tyrosine kinase (2) 2
15-hydroxy-11 alpha,9 alpha-prosta-5,13-dienoic acid - pharmacology (1) 1
4-aminopyridine - pharmacology (1) 1
actin (1) 1
activated (1) 1
adrenergic beta-agonists - pharmacology (1) 1
adult (1) 1
advanced basic science (1) 1
aged, 80 and over (1) 1
air breathing (1) 1
airway hyperresponsiveness (1) 1
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1. Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature
by Janssen, Luke J and Tazzeo, Tracy
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 2002, Volume 301, Issue 3, pp. 1060 - 1066
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Pulmonary Veins - drug effects | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Swine | Pulmonary Veins - physiology | Receptors, Thromboxane - antagonists & inhibitors | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | Isoprostanes - physiology | Pulmonary Artery - drug effects | Lung - physiology | Receptors, Prostaglandin E, EP3 Subtype | Vasoconstriction - drug effects | Pulmonary Artery - physiology | Receptors, Prostaglandin E - physiology | Animals | Isoprostanes - pharmacology | Receptors, Prostaglandin E - agonists | Receptors, Thromboxane - agonists | Lung - drug effects | Receptors, Prostaglandin E - antagonists & inhibitors | Dinoprostone - analogs & derivatives | Receptors, Thromboxane - physiology | In Vitro Techniques | Lung - blood supply
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2. Full Text Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction
by Dyrda, Peter and Tazzeo, Tracy and DoHarris, Lindsay and Nilius, Berndt and Roman, Horia Nicolae and Lauzon, Anne-Marie and Aziz, Tariq and Lukic, Dusan and Janssen, Luke J
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 02/2011, Volume 44, Issue 2, pp. 213 - 221
Airway smooth muscle | TRPV channels | Thermoplasty | Myosin | Asthma | Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Hot Temperature - adverse effects | Acetylcholine - pharmacology | Isometric Contraction - drug effects | Myosin-Light-Chain Kinase - metabolism | Actins - metabolism | Trachea - drug effects | Bronchi - drug effects | Trachea - pathology | Muscle, Smooth - drug effects | TRPV Cation Channels - metabolism | Animals | Cattle | Isoproterenol - pharmacology | Protein Denaturation | Trachea - physiology | Muscle, Smooth - physiology | Myosins - metabolism | Bronchi - physiology | In Vitro Techniques | Isometric Contraction - physiology | Trachea - injuries | Index Medicus
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3. Full Text KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase
by Luke J. Janssen and Tracy Tazzeo and Jianmin Zuo and Evi Pertens and Shaf Keshavjee
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 10/2004, Volume 287, Issue 4, pp. 852 - 858
Respiratory System | Physiology | Life Sciences & Biomedicine | Science & Technology | Amides - pharmacology | Respiratory Mucosa - drug effects | Humans | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | rhoA GTP-Binding Protein - metabolism | Bronchi - drug effects | Muscle, Smooth - drug effects | Calcium - physiology | Potassium Chloride - pharmacology | rho-Associated Kinases | Muscle, Smooth - physiology | Respiratory Mucosa - physiology | Bronchi - physiology | Pyridines - pharmacology | In Vitro Techniques | Protein-Serine-Threonine Kinases - metabolism | Index Medicus
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4. Full Text Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling
by Caiqiong Liu and Tracy Tazzeo and Luke J. Janssen
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, pp. 1177 - 1184
Cholinergic responsiveness | Relaxation | Rho kinase | Sarcoplasmic reticulum | Airway smooth muscle | Contraction | RhoA | Respiratory System | Physiology | Life Sciences & Biomedicine | Science & Technology | Amides - pharmacology | Dinoprostone - pharmacology | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Enzyme Inhibitors - pharmacology | Carbachol - pharmacology | Muscle, Smooth - drug effects | Animals | Calcium - physiology | Isoprostanes - pharmacology | Cattle | Bronchial Hyperreactivity - physiopathology | rho-Associated Kinases | Trachea - physiology | Muscle, Smooth - physiology | Pyridines - pharmacology | In Vitro Techniques | Intracellular Signaling Peptides and Proteins - physiology | Studies | Signal transduction | Airway management | Protease inhibitors | Respiratory diseases | Kinases | Asthma | Index Medicus
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5. Full Text E-Ring Isoprostane Augments Cholinergic Neurotransmission in Bovine Trachealis via FP Prostanoid Receptors
by Paredes, Christine and Tazzeo, Tracy and Janssen, Luke J
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 12/2007, Volume 37, Issue 6, pp. 739 - 747
Isoprostane | Oxidative stress | Prostanoid receptor | Cholinergic neurotransmission | Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Choline - metabolism | Trachea - cytology | Acetylcholine - pharmacology | Trachea - drug effects | Trachea - metabolism | Receptors, Prostaglandin - metabolism | Dose-Response Relationship, Drug | Muscle, Smooth - drug effects | Animals | Receptors, Prostaglandin - agonists | Isoprostanes - pharmacology | Cattle | Muscle Contraction - drug effects | Receptors, Thromboxane - agonists | Receptors, Thromboxane - antagonists & inhibitors | Molecular Mimicry - drug effects | Synaptic Transmission - drug effects | Neurons - metabolism | Muscle Relaxation - drug effects | Muscle, Smooth - cytology | In Vitro Techniques | Neurons - drug effects | Receptors, Prostaglandin - antagonists & inhibitors | Index Medicus
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6. Full Text Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle
by Tazzeo, Tracy and Miller, John and Janssen, Luke J
British journal of pharmacology, ISSN 0007-1188, 10/2003, Volume 140, Issue 4, pp. 759 - 763
Prostanoid receptors | free radicals | pulmonary hypertension | oxidative stress | reactive oxygen species | Oxidative stress | Reactive oxygen species | Free radicals | Pulmonary hypertension | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Humans | Prostaglandins E - pharmacology | Alprostadil - analogs & derivatives | Bronchial Arteries - physiology | Receptors, Thromboxane A2, Prostaglandin H2 - physiology | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Bronchial Arteries - drug effects | Swine | Receptors, Thromboxane A2, Prostaglandin H2 - drug effects | Dinoprost - analogs & derivatives | Dioxanes - pharmacology | Dinoprost - pharmacology | Muscle, Smooth, Vascular - drug effects | Amides - pharmacology | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | F2-Isoprostanes - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | Alprostadil - pharmacology | Vasoconstriction - drug effects | Isoprostanes - antagonists & inhibitors | Animals | Isoprostanes - pharmacology | Signal Transduction - drug effects | Genistein - pharmacology | Dinoprostone - analogs & derivatives | Prostaglandins F, Synthetic - pharmacology | Signal Transduction - physiology | Pyridines - pharmacology | Dinoprostone - antagonists & inhibitors | Index Medicus | Papers
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7. Full Text Isoprostanes constrict human radial artery by stimulation of thromboxane receptors, Ca2+ release, and RhoA activation
by Mueed, Irem, PhD and Tazzeo, Tracy, BSc and Liu, Ciaqiong, BSc and Pertens, Evi, BSc and Zhang, Yongde, PhD and Cybulski, Irene, MD and Semelhago, Lloyd, MD and Noora, Joseph, MD and Lamy, Andre, MD and Teoh, Kevin, MD and Chu, Victor, MD and Janssen, Luke J., PhD
The Journal of thoracic and cardiovascular surgery, ISSN 0022-5223, 2008, Volume 135, Issue 1, pp. 131 - 138
Cardiothoracic Surgery | Cardiac & Cardiovascular Systems | Respiratory System | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Surgery | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Pneumology | Vasoconstrictor Agents - pharmacology | Signal Transduction | Calcium - metabolism | Humans | rhoA GTP-Binding Protein - metabolism | Vasoconstriction - drug effects | Receptors, Thromboxane A2, Prostaglandin H2 | Radial Artery - physiopathology | Isoprostanes - pharmacology | Receptors, Thromboxane - drug effects | Tissue and Organ Harvesting | Radial Artery - drug effects | In Vitro Techniques | Index Medicus | Abridged Index Medicus
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8. Full Text Role of Tyrosine Phosphorylation in U46619-induced Vasoconstriction of Pulmonary Vasculature and Its Modulation by Genistein, Daidzein, and Equol
by Liu, Caiqiong and Tazzeo, Tracy and Lippton, Howard and Janssen, Luke J
Journal of cardiovascular pharmacology, ISSN 0160-2446, 10/2007, Volume 50, Issue 4, pp. 441 - 448
Pulmonary vascular smooth muscle | Tyrosine kinase | ROCK | Contraction | RhoA | Thromoboxane A | Cardiac & Cardiovascular Systems | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Pulmonary Veins - drug effects | Protein-Tyrosine Kinases - metabolism | Isoflavones - pharmacology | Equol | Pulmonary Veins - metabolism | Phosphotyrosine - metabolism | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Pulmonary Artery - metabolism | Cattle | Potassium Chloride - pharmacology | Pulmonary Veins - physiology | Caffeine - pharmacology | Phosphorylation - drug effects | Phytoestrogens - pharmacology | Muscle, Smooth, Vascular - drug effects | Pulmonary Artery - drug effects | Calcimycin - pharmacology | Vasoconstriction - drug effects | Blotting, Western | Pulmonary Artery - physiology | Tyrosine - metabolism | Animals | Proteins - metabolism | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Genistein - pharmacology | Proteins - chemistry | In Vitro Techniques | Index Medicus
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9. Full Text Reduction of arterial graft smooth muscle mass by moderate heat therapy
by Mueed, Irem and Tazzeo, Tracy and Doharris, Lindsay and Aziz, Tariq and Chu, Victor and Janssen, Luke J
Translational research : the journal of laboratory and clinical medicine, ISSN 1931-5244, 2011, Volume 157, Issue 3, pp. 128 - 138
Internal Medicine | Life Sciences & Biomedicine | Medical Laboratory Technology | Medicine, General & Internal | General & Internal Medicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Biological and medical sciences | General aspects | Investigative techniques, diagnostic techniques (general aspects) | Medical sciences | Radial Artery - anatomy & histology | Humans | Middle Aged | Postoperative Complications - prevention & control | Femoral Artery - anatomy & histology | Radio Waves - therapeutic use | Radial Artery - transplantation | Coronary Vasospasm - prevention & control | Models, Animal | Femoral Artery - transplantation | Radial Artery - physiology | Muscle, Smooth, Vascular - physiology | Hot Temperature - therapeutic use | Rabbits | Coronary Artery Bypass - methods | Vasoconstriction | Rats | Coronary Artery Bypass - adverse effects | Animals | Perfusion | Muscle, Smooth, Vascular - anatomy & histology | Aged | Femoral Artery - physiology | In Vitro Techniques | Vascular Patency | Coronary artery bypass | Transplantation of organs, tissues, etc | Analysis | Index Medicus | Abridged Index Medicus
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10. Full Text Enhanced Myosin Phosphatase and Ca2+-Uptake Mediate Adrenergic Relaxation of Airway Smooth Muscle
by Janssen, Luke J and Tazzeo, Tracy and Zuo, Jianmin
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 04/2004, Volume 30, Issue 4, pp. 548 - 554
Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology
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11. Full Text Membrane potassium currents in human radial artery and their regulation by nitric oxide donor
by Zhang, Yongde and Tazzeo, Tracy and Chu, Victor and Janssen, Luke J
Cardiovascular research, ISSN 0008-6363, 07/2006, Volume 71, Issue 2, pp. 383 - 392
current | ATP-sensitive | Voltage-dependent | Nitric oxide | activated | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Muscle, Smooth, Vascular - metabolism | Humans | Middle Aged | Male | Penicillamine - analogs & derivatives | Guanylate Cyclase - antagonists & inhibitors | Potassium Channels - metabolism | Quinoxalines - pharmacology | Radial Artery | Glyburide - pharmacology | Potassium Channels, Voltage-Gated - metabolism | Oxadiazoles - pharmacology | Potassium Channels, Calcium-Activated - metabolism | Aged, 80 and over | Adult | Female | Nitric Oxide Donors - pharmacology | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Muscle, Smooth, Vascular - drug effects | Membrane Potentials - drug effects | Blotting, Western - methods | Penicillamine - pharmacology | Guanylate Cyclase - metabolism | Potassium Channels, Voltage-Gated - antagonists & inhibitors | Peptides - pharmacology | Tetraethylammonium Compounds - pharmacology | Patch-Clamp Techniques | Aged | Potassium Channels, Calcium-Activated - antagonists & inhibitors | In Vitro Techniques | Ion Channel Gating - drug effects | Coronary artery bypass | Index Medicus
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12. Full Text Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles
by Luke J. Janssen and Jennifer Wattie and Hwa Lu-Chao and Tracy Tazzeo
Journal of Applied Physiology, ISSN 8750-7587, 09/2001, Volume 91, Issue 3, pp. 1142 - 1151
Calcium ion-dependent chlorine ion current | Tyrosine kinase | Airway smooth muscle contraction | Rho kinase | Genistein | Phosphatidylinositol 3-kinase | Calcium ion-adenosinetriphosphatase | Airway hyperresponsiveness | Physiology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Air breathing | Vertebrates: respiratory system | Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics | Calcium-Transporting ATPases - antagonists & inhibitors | Calcium - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Sarcoplasmic Reticulum - enzymology | Muscle Relaxation - physiology | Bronchial Hyperreactivity - physiopathology | Chlorides - metabolism | rho-Associated Kinases | Trachea - physiology | Calcium-Transporting ATPases - metabolism | Indoles - pharmacology | Muscle, Smooth - physiology | Bronchi - physiology | Cholinergic Agonists - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Sarcoplasmic Reticulum Calcium-Transporting ATPases | Carbachol - pharmacology | Patch-Clamp Techniques | Animals | Muscle Contraction - drug effects | Muscle Contraction - physiology | Dogs | Genistein - pharmacology | Muscle Relaxation - drug effects | Receptors, Muscarinic - physiology | Ions | Throat | Bronchitis | Muscular system | Calcium | Respiratory system | Index Medicus
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13. Full Text Membrane potassium currents in human radial artery and their regulation by nitric oxide donor
: Reactive oxygen species as cardiovascular signaling molecules
by YONGDE ZHANG and TAZZEO, Tracy and CHU, Victor and JANSSEN, Luke J
Cardiovascular research, ISSN 0008-6363, 2006, Volume 71, Issue 2, pp. 383 - 392
Cardiology. Vascular system | Biological and medical sciences | Medical sciences
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14. Full Text Enhanced Myosin Phosphatase and Ca^sup 2+^-Uptake Mediate Adrenergic Relaxation of Airway Smooth Muscle
by Luke J Janssen and Tracy Tazzeo and Jianmin Zuo
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 04/2004, Volume 30, Issue 4, p. 548
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