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in vitro techniques (12) 12
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muscle, smooth - physiology (7) 7
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pyridines - pharmacology (3) 3
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8-epi-prostaglandin f2-alpha (2) 2
8-iso-prostaglandin e-2 (2) 2
acetylcholine - pharmacology (2) 2
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bronchial hyperreactivity - physiopathology (2) 2
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intracellular signaling peptides and proteins (2) 2
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by Feig, Denice S and Donovan, Lois E and Corcoy, Rosa and Murphy, Helen R and Murphy, Kellie E and Amiel, Stephanie A and Hunt, Katharine F and Asztalos, Elizabeth and Barrett, Jon F R and Sanchez, J Johanna and de Leiva, Alberto and Hod, Moshe and Jovanovic, Lois and Keely, Erin and McManus, Ruth and Hutton, Eileen K and Meek, Claire L and Stewart, Zoe A and Wysocki, Tim and O'Brien, Robert and Ruedy, Katrina and Kollman, Craig and Tomlinson, George and Grisoni, Jeannie and Byrne, Carolyn and Davenport, Katy and Neoh, Sandra and Gougeon, Claire and Oldford, Carolyn and Young, Catherine and Green, Louisa and Rossi, Benedetta and Rogers, Helen and Cleave, Barbara and Strom, Michelle and Adelantado, Juan María and Isabel Chico, Ana and Tundidor, Diana and Malcolm, Janine and Henry, Kathy and Morris, Damian and Morris, Juliet and Rayman, Gerry and Fowler, Duncan and Mitchell, Susan and Rosier, Josephine and Temple, Rosemary and Turner, Jeremy and Canciani, Gioia and Hewapathirana, Niranjala and Piper, Leanne and Kudirka, Anne and Watson, Margaret and Bonomo, Matteo and Pintaudi, Basilio and Bertuzzi, Federico and Daniela, Giuseppina and Mion, Elena and Lowe, Julia and Halperin, Ilana and Rogowsky, Anna and Adib, Sapida and Lindsay, Robert and Carty, David and Crawford, Isobel and Mackenzie, Fiona and McSorley, Therese and Booth, John and McInnes, Natalia and Smith, Ada and Stanton, Irene and Tazzeo, Tracy and Weisnagel, John and Mansell, Peter and Jones, Nia and Babington, Gayna and Spick, Dawn and MacDougall, Malcolm and Chilton, Sharon and Cutts, Terri and Perkins, Michelle and Scott, Eleanor and Endersby, Del and Dover, Anna and Dougherty, Frances and Johnston, Susan and Heller, Simon and Novodorsky, Peter and Hudson, Sue and Nisbet, Chloe and Ransom, Thomas and Coolen, Jill and Baxendale, Darlene and Holt, Richard and Forbes, Jane and Martin, Nicki and Walbridge, Fiona and Dunne, Fidelma and Conway, Sharon and Egan, Aoife and ... and CONCEPTT Collaborative Grp and CONCEPTT Collaborative Group
The Lancet, ISSN 0140-6736, 11/2017, Volume 390, Issue 10110, pp. 2347 - 2359
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 08/2012, Volume 303, Issue 4, pp. L334 - L342
Journal Article
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 10/2004, Volume 287, Issue 4, pp. L852 - L858
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2003, Volume 140, Issue 4, pp. 759 - 763
We investigated the effects of five different isoprostanes (8‐iso PGE1, 8‐iso PGE2, 8‐iso PGF1α, 8‐iso PGF2α and 8‐iso PGF2β) on vasomotor tone in human and... 
Prostanoid receptors | free radicals | pulmonary hypertension | oxidative stress | reactive oxygen species | Oxidative stress | Reactive oxygen species | Free radicals | Pulmonary hypertension | CONDENSATE | LIPID-PEROXIDATION | OXIDANT STRESS | RHO-KINASE | REPERFUSION | ANGIOTENSIN | prostanoid receptors | PHARMACOLOGY & PHARMACY | HYPERTENSION | CANINE | Humans | Prostaglandins E - pharmacology | Alprostadil - analogs & derivatives | Bronchial Arteries - physiology | Receptors, Thromboxane A2, Prostaglandin H2 - physiology | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Bronchial Arteries - drug effects | Swine | Receptors, Thromboxane A2, Prostaglandin H2 - drug effects | Dinoprost - analogs & derivatives | Dioxanes - pharmacology | Dinoprost - pharmacology | Muscle, Smooth, Vascular - drug effects | Amides - pharmacology | Vasoconstrictor Agents - pharmacology | Dinoprostone - pharmacology | F2-Isoprostanes - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | Alprostadil - pharmacology | Vasoconstriction - drug effects | Isoprostanes - antagonists & inhibitors | Animals | Isoprostanes - pharmacology | Signal Transduction - drug effects | Genistein - pharmacology | Dinoprostone - analogs & derivatives | Prostaglandins F, Synthetic - pharmacology | Signal Transduction - physiology | Pyridines - pharmacology | Dinoprostone - antagonists & inhibitors | Papers
Journal Article
American Journal of Physiology, ISSN 1040-0605, 08/2012, Volume 303, Issue 4, p. L334
  Caffeine is sometimes used in cell physiological studies to release internally stored ... We obtained evidence that caffeine may also act through a different... 
Phosphorylation | Calcium | Kinases | Cells | Binding sites | Caffeine
Journal Article
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, pp. L1177 - L1184
We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR). In this study, we examined the signaling mechanisms underlying... 
Journal Article
American Journal of Physiology, ISSN 1040-0605, 12/2006, Volume 291, Issue 6, p. L1177
  We previously reported the ability of isoprostanes to induce airway hyperresponsiveness (AHR). In this study, we examined the signaling mechanisms underlying... 
Studies | Signal transduction | Airway management | Protease inhibitors | Respiratory diseases | Kinases | Asthma
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 09/2001, Volume 91, Issue 3, pp. 1142 - 1151
We investigated the mechanisms underlying muscarinic excitation-contraction coupling in canine airway smooth muscle using organ bath, fura 2 fluorimetric, and... 
Calcium ion-dependent chlorine ion current | Tyrosine kinase | Airway smooth muscle contraction | Rho kinase | Genistein | Phosphatidylinositol 3-kinase | Calcium ion-adenosinetriphosphatase | Airway hyperresponsiveness | airway hyperresponsiveness | SPORT SCIENCES | PHYSIOLOGY | CA2+ STORES | DISTINCT PATHWAYS | calcium ion-adenosinetriphosphatase | AIRWAY MYOCYTES | tyrosine kinase | calcium ion-dependent chlorine ion current | airway smooth muscle contraction | CURRENTS | CYTOSOLIC CALCIUM | SWINE TRACHEALIS | SIGNAL-TRANSDUCTION | genistein | ACETYLCHOLINE-INDUCED CONTRACTIONS | RECEPTORS | CANINE | phosphatidylinositol 3-kinase | Calcium-Transporting ATPases - antagonists & inhibitors | Calcium - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Sarcoplasmic Reticulum - enzymology | Muscle Relaxation - physiology | Bronchial Hyperreactivity - physiopathology | Chlorides - metabolism | rho-Associated Kinases | Trachea - physiology | Calcium-Transporting ATPases - metabolism | Indoles - pharmacology | Muscle, Smooth - physiology | Bronchi - physiology | Cholinergic Agonists - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Sarcoplasmic Reticulum Calcium-Transporting ATPases | Carbachol - pharmacology | Patch-Clamp Techniques | Animals | Muscle Contraction - drug effects | Muscle Contraction - physiology | Dogs | Genistein - pharmacology | Muscle Relaxation - drug effects | Receptors, Muscarinic - physiology
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2004, Volume 30, Issue 4, pp. 548 - 554
We examined the mechanisms underlying relaxations evoked by isoproterenol (Iso) in isolated porcine, bovine, or human tracheal and bronchial tissues (TSM and... 
CALCIUM-CHANNEL BLOCKER | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | TRACHEAL MYOCYTES | CELL BIOLOGY | BRL-38227 | ACTIVATOR | CONTRACTION | CA2 | RESPIRATORY SYSTEM | NIFEDIPINE | ASTHMA
Journal Article
Journal Article
by Feig, Denice S and Asztalos, Elizabeth and Corcoy, Rosa and De Leiva, Alberto and Donovan, Lois and Hod, Moshe and Jovanovic, Lois and Keely, Erin and Kollman, Craig and McManus, Ruth and Murphy, Kellie and Ruedy, Katrina and Sanchez, J.Johanna and Tomlinson, George and Murphy, Helen R and Feig, Denice and Cleave, Barbara and Donat, Diane and Gandhi, Shital and Strom, Michelle and Chico, Ana Isabel and José Martínez, M and Sánchez, Mireia and Tundidor, Diana and Amiel, Stephanie and Hunt, Katharine and Green, Louisa and Rogers, Helen and Rossi, Benedetta and Stodhart, Ben and Bonomo, Matteo and Bertuzzi, Federico and Corica, Giuseppina D and Fazio, Silvana and Giro, Roberto and Mion, Elena and Moletta, Andrea and Pintaudi, Basilio and Sorrentino, Rosa and Booth, John and McInnes, Natalia and Nykamp, Adelle and Otto, Rose and Smith, Ada and Stanton, Irene and Tazzeo, Tracy and Oldford, Carolyn and Young, Catherine and Gougeon, Claire and Houlden, Robyn and Breen, Adriana and Castorino, Kristin and Sansum, William and Erin Keely, Keely and Clark, Heather and Gaudet, Laura and Karovitch, Alan and Malcolm, Janine and Lowe, Julia and Rogowsky, Anna and Kudirka, Anne and Watson, Margaret and Morris, Damian and Farnworth, Frances and Fowler, Duncan and Mitchell, Sue and Rosier, Josephine and Murphy, Helen and Byrne, Caroline and Davenport, Katy and Grisoni, Jeannie and Mulrennan, Sandra and Neoh, Sandra and O'Sullivan, Esther and Simmons, David and Stewart, Zoe and Templin, Heike and Helen Murphy, Murphy and Turner, Jeremy and Canciani, Gioia and Hewapathirana, Niranjala and Jones, Louise and Piper, Leanne and Temple, Rosemary and Wallace, Tara and Maitland, Rahat and Banerjee, Anita and Briley, Annette and Brackenridge, Anna and Gilby, Pam and Gill, Carolyn and Reid, Anna and Singh, Claire and White, Sara and Wolfs, Maria and Scott, Eleanor and Endersby, Del and Maresh, Michael and Kearney, Gretta and Morris, Juliet and ... and CONCEPTT Collaborative Grp and CONCEPTT Collaborative Group and on behalf of the CONCEPTT Collaborative Group
BMC Pregnancy and Childbirth, ISSN 1471-2393, 07/2016, Volume 16, Issue 1, p. 167
Journal Article