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Science, ISSN 0036-8075, 10/2005, Volume 310, Issue 5748, pp. 644 - 648
Journal Article
NATURE GENETICS, ISSN 1061-4036, 09/2015, Volume 47, Issue 9, pp. 1020 - 1020
TCF3-HLF-positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct mutation, gene expression and... 
PROGENITOR CELLS | CHROMOSOMAL TRANSLOCATIONS | SET ENRICHMENT ANALYSIS | RAS PATHWAY | GENETICS & HEREDITY | GENE-EXPRESSION | B-CELL DIFFERENTIATION | SEQUENCING DATA | CHAIN REARRANGEMENT | TRANSCRIPTION FACTOR | HEMATOPOIETIC STEM | Sequence Deletion | Oncogene Proteins, Fusion - metabolism | Coculture Techniques | Genomics | Humans | Drug Resistance, Neoplasm | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Antineoplastic Agents - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | DNA Mutational Analysis | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Immunoglobulin Light Chains, Surrogate - genetics | Gene Expression | Genetic Association Studies | Kaplan-Meier Estimate | PAX5 Transcription Factor - genetics | Mice, SCID | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Oncogene Proteins, Fusion - genetics | Mice, Inbred NOD | Mutation | Cohort Studies | Gene mutations | Genetic aspects | Acute lymphocytic leukemia | Research | Identification and classification | Health aspects | Risk factors | Bone marrow | Genes | Leukemia | cytarabine | integrative | leukemic stem cell | drug activity profiling | panobinostat | mTOR inhibitor | genomics | glucocorticoids | bortezomib | ABT-199 | dexamethasone | HSP90 | TCF3-PBX1 | vincristine | BH3-mimetics | leukemia xenograft model | next generation sequencing | TCF3-HLF | venetoclax | anthracycline | acute lymphoblastic leukemia | AUY922 | BCL2 | drug resistance | prednisone
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3194 - 3194
Journal Article
BMC Genomics, ISSN 1471-2164, 09/2016, Volume 17, Issue 1
Background: Genome-wide CRISPR-Cas9 dropout screens can identify genes whose knockout affects cell viability. Recent CRISPR screens detected thousands of... 
NRAS | Driver mutations | Kinase | Negative selection | EGFR | Whole genome CRISPR screen | Dropout | CELLS | DISCOVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | GENES | GENETICS & HEREDITY | Genome-wide association studies | Usage | Research | Gene mutations | Cancer cells
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2006, Volume 24, Issue 16, pp. 2480 - 2489
Journal Article
Nature, ISSN 0028-0836, 11/2006, Volume 444, Issue 7118, pp. 444 - 454
Journal Article
Current Gene Therapy, ISSN 1566-5232, 07/2015, Volume 15, Issue 4, pp. 416 - 427
Journal Article