Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (105) 105
kidney transplantation (83) 83
transplantation (82) 82
female (76) 76
male (76) 76
adult (74) 74
middle aged (69) 69
index medicus (68) 68
surgery (53) 53
kidneys (45) 45
immunosuppressive agents - therapeutic use (42) 42
treatment outcome (40) 40
tacrolimus (39) 39
immunology (35) 35
immunosuppressive agents - administration & dosage (33) 33
cyclosporine (32) 32
graft rejection - prevention & control (32) 32
sirolimus (32) 32
kidney transplantation - adverse effects (29) 29
recipients (27) 27
time factors (26) 26
immunosuppressive agents - adverse effects (25) 25
organ transplant recipients (25) 25
retrospective studies (25) 25
aged (24) 24
everolimus (23) 23
prospective studies (23) 23
risk factors (23) 23
transplants & implants (23) 23
immunosuppression (22) 22
pharmacology & pharmacy (22) 22
diseases of the genitourinary system. urology (21) 21
efficacy (21) 21
mycophenolic acid - analogs & derivatives (21) 21
biopsy (20) 20
drug therapy, combination (20) 20
immunosuppressive agents - pharmacokinetics (20) 20
pharmacokinetics (20) 20
safety (20) 20
young adult (20) 20
adolescent (19) 19
kidney transplantation - immunology (19) 19
mycophenolate-mofetil (19) 19
acute rejection (18) 18
calcineurin inhibitors (17) 17
graft rejection (17) 17
mycophenolate mofetil (17) 17
follow-up studies (16) 16
rejection (16) 16
cyclosporine - therapeutic use (15) 15
dose-response relationship, drug (15) 15
immunosuppressive agents (15) 15
mycophenolic acid - administration & dosage (15) 15
mycophenolic acid - therapeutic use (15) 15
renal-transplantation (15) 15
transplante de rim (15) 15
graft survival (14) 14
kidney transplantation - mortality (14) 14
sirolimus - adverse effects (14) 14
sirolimus - therapeutic use (14) 14
tacrolimus - administration & dosage (14) 14
allergy and immunology (13) 13
renal transplantation (13) 13
urology & nephrology (13) 13
kidney-transplantation (12) 12
sirolimus - administration & dosage (12) 12
analysis (11) 11
cyclosporine - administration & dosage (11) 11
drug administration schedule (11) 11
drug monitoring (11) 11
graft rejection - epidemiology (11) 11
graft rejection - immunology (11) 11
immunosuppressive agents - blood (11) 11
mycophenolic acid (11) 11
outcomes (11) 11
survival (11) 11
tacrolimus - therapeutic use (11) 11
area under curve (10) 10
delayed graft function (10) 10
kidney transplant (10) 10
kidney transplantation - methods (10) 10
multicenter (10) 10
patients (10) 10
renal function (10) 10
risk (10) 10
therapeutic drug monitoring (10) 10
toxicology (10) 10
brazil (9) 9
glomerular filtration rate (9) 9
health aspects (9) 9
immunotherapy (9) 9
kidney - pathology (9) 9
kidney diseases (9) 9
medical laboratory technology (9) 9
sirolimus - analogs & derivatives (9) 9
tacrolimus - adverse effects (9) 9
tissue donors (9) 9
corticosteroids (8) 8
cyclosporine - pharmacokinetics (8) 8
exposure (8) 8
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Tacrolimus Once-Daily Formulation in the Prophylaxis of Transplant Rejection in Renal or Liver Allograft Recipients: A Viewpoint by Helio Tedesco Silva Jr
by Helio Tedesco Silva Jr
Drugs, ISSN 0012-6667, 2007, Volume 67, Issue 13, pp. 1944 - 1945
Controlled release drugs | Tacrolimus | Renal transplant rejection | Adis Drug Profiles | Liver transplant rejection | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Tacrolimus - therapeutic use | Liver Transplantation | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Immunosuppressive Agents - adverse effects | Kidney Transplantation | Patient Compliance | Tacrolimus - adverse effects | Delayed-Action Preparations | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text The challenges associated with a calcineurin inhibitor free regimen after heart transplantation
by Silva, Helio Tedesco
Transplantation, ISSN 0041-1337, 09/2018, p. 1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial
by Rostaing, Lionel, MD, PhD and Bunnapradist, Suphamai, MD and Grinyó, Josep M., MD and Ciechanowski, Kazimierz, MD, PhD and Denny, Jason E., MD and Silva, Helio Tedesco, MD and Budde, Klemens, MD and Envarsus Study Grp and Envarsus Study Group
American Journal of Kidney Diseases, ISSN 0272-6386, 2015, Volume 67, Issue 4, pp. 648 - 659
Background 1-year data from this trial showed the noninferiority of a novel once-daily extended-release tacrolimus (LCPT; Envarsus XR) to immediate-release... 
Nephrology | tacrolimus | pill burden | transplant recipient | randomized controlled trial (RCT) | kidney transplantation | efficacy | Immunosuppression | bioavailability | treatment failure | Envarsus | safety | end-stage renal disease (ESRD) | formulation | biopsy-proven acute rejection | extended-release | CAPSULES | NONCOMPLIANCE | A-DAY | SOLID-ORGAN TRANSPLANTATION | RENAL-TRANSPLANT | CONVERSION | ADHERENCE | ACUTE REJECTION | PHARMACOKINETICS | UROLOGY & NEPHROLOGY | OUTCOMES | mmunosuppression | Prospective Studies | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Male | Kidney Transplantation | Time Factors | Adult | Female | Aged | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Early conversion of pediatric kidney transplant patients to everolimus with reduced tacrolimus and steroid elimination: Results of a randomized trial
by Tönshoff, Burkhard and Ettenger, Robert and Dello Strologo, Luca and Marks, Stephen D and Pape, Lars and Tedesco‐Silva, Helio and Bjerre, Anna and Christian, Martin and Meier, Matthias and Martzloff, El‐Djouher and Rauer, Barbara and Ng, Jennifer and Lopez, Patricia
American Journal of Transplantation, ISSN 1600-6135, 03/2019, Volume 19, Issue 3, pp. 811 - 822
In a 12‐month, multicenter, open‐label study, 106 children were randomized at 4 to 6 weeks after kidney transplantation to switch to everolimus with reduced... 
immunosuppressant—mechanistic target of rapamycin: everolimus | immunosuppressant—calcineurin inhibitor: tacrolimus | clinical research/practice | immunosuppressive regimens—minimization/withdrawal | kidney transplantation/nephrology | pediatrics | MAMMALIAN TARGET | SURGERY | MULTICENTER | CALCINEURIN INHIBITOR THERAPY | EFFICACY | RAPAMYCIN INHIBITORS | RECIPIENTS | CHILDREN | TRANSPLANTATION | immunosuppressive regimens-minimization/withdrawal | SPARING REGIMENS | LOW-DOSE CYCLOSPORINE | DE-NOVO THERAPY | immunosuppressant-mechanistic target of rapamycin: everolimus | immunosuppressant-calcineurin inhibitor: tacrolimus | Pediatrics | Transplantation | Kidneys | Tacrolimus | Mycophenolic acid | Renal function | Transplants & implants | Immunoproliferative diseases | Patients | Glomerular filtration rate | Graft rejection | Biopsy | Lymphocytes | Mycophenolate mofetil | Steroid hormones | Kidney transplantation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Everolimus plus early tacrolimus minimization: a phase III, randomized, open‐label, multicentre trial in renal transplantation
by Langer, Robert M and Hené, Ronald and Vitko, Stefan and Christiaans, Maarten and Tedesco‐Silva, Helio and Ciechanowski, Kazimierz and Cassuto, Elisabeth and Rostaing, Lionel and Vilatoba, Mario and Machein, Uwe and Ulbricht, Bettina and Junge, Guido and Dong, Gaohong and Pascual, Julio
Transplant International, ISSN 0934-0874, 05/2012, Volume 25, Issue 5, pp. 592 - 602
There is increasing interest in tacrolimus‐minimization regimens. ASSET was an open‐label, randomized, 12‐month study of everolimus plus tacrolimus in de‐novo... 
everolimus | calcineurin inhibitor minimization | tacrolimus | mammalian target of rapamycin inhibitor | proliferation signal inhibitors | SURGERY | EFFICACY | EARLY CYCLOSPORINE WITHDRAWAL | AZATHIOPRINE | RISK | CALCINEURIN INHIBITORS | RECIPIENTS | TRANSPLANTATION | ACUTE REJECTION | REDUCTION | MYCOPHENOLATE-MOFETIL | SIROLIMUS | Sirolimus - analogs & derivatives | Glomerular Filtration Rate | Graft Rejection - prevention & control | Humans | Middle Aged | Graft Rejection - etiology | Male | Treatment Outcome | Tacrolimus - adverse effects | Kidney Transplantation - methods | Calcineurin Inhibitors | Sirolimus - administration & dosage | Kidney Transplantation - physiology | Time Factors | Adult | Female | Immunosuppressive Agents - adverse effects | Kidney Transplantation - immunology | Everolimus | Immunosuppressive Agents - administration & dosage | Kidney Transplantation - adverse effects | Tacrolimus - administration & dosage | Clinical trials | Transplantation | Kidneys | Angiogenesis inhibitors | Tacrolimus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Clinicopathological Characteristics and Effect of Late Acute Rejection on Renal Transplant Outcomes
by Rodrigues, Carolina A and Franco, Marcello F and Cristelli, Marina P and Pestana, Jose O.M and Tedesco-Silva, Helio
Transplantation, ISSN 0041-1337, 10/2014, Volume 98, Issue 8, pp. 885 - 892
BACKGROUNDLate acute rejection (LAR) has been associated with inferior kidney allograft outcomes. METHODSWe retrospectively evaluated 355 episodes of... 
Chronic rejection | Acute rejection | Graft loss | Late rejection | Kidney transplant | SURGERY | IMPACT | KIDNEY-TRANSPLANTATION | INFLAMMATION | ALLOGRAFT SURVIVAL | IMMUNOLOGY | TRANSPLANTATION | Acute Disease | Glomerular Filtration Rate | Kidney - pathology | Humans | Middle Aged | Proportional Hazards Models | Male | Treatment Outcome | Adult | Female | Retrospective Studies | Graft Rejection - pathology | Kidney Transplantation - adverse effects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The Long Journey of mTOR Inhibitors and the Long Path That Is Still Ahead
by Tedesco Silva, Helio
Transplantation, ISSN 0041-1337, 02/2018, Volume 102, Issue 2S Suppl 1, pp. S1 - S2
RAPAMYCIN | SURGERY | IMMUNOLOGY | TRANSPLANTATION
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Targeting JAK/STAT Signaling to Prevent Rejection After Kidney Transplantation: A Reappraisal
by Baan, Carla C and Kannegieter, Nynke M and Felipe, Claudia Rosso and Tedesco Silva, Helio
Transplantation, ISSN 0041-1337, 09/2016, Volume 100, Issue 9, pp. 1833 - 1839
ABSTRACTThe profound involvement of cytokines in allograft rejection makes the molecules that control their actions, members of the Jak-Stat pathway, ideal... 
SURGERY | ALLOGRAFT-REJECTION | ACTIVATION | IMMUNOLOGY | RECIPIENTS | REGIMENS | CHEMOTHERAPY | JAK INHIBITOR CP-690,550 | TRANSPLANTATION | TOFACITINIB | IMMUNOSUPPRESSIVE DRUGS | T-CELLS | STANDARD | Phosphorylation | Humans | Immunosuppressive Agents - pharmacokinetics | Kidney - enzymology | Kidney - immunology | STAT Transcription Factors - metabolism | Protein Kinase Inhibitors - adverse effects | Molecular Targeted Therapy | Janus Kinase 3 - antagonists & inhibitors | Drug Dosage Calculations | Janus Kinase 3 - metabolism | Immunosuppressive Agents - administration & dosage | Graft Rejection - enzymology | Kidney - surgery | Protein Kinase Inhibitors - pharmacokinetics | Kidney - drug effects | Graft Rejection - prevention & control | Risk Factors | Treatment Outcome | Protein Kinase Inhibitors - administration & dosage | Animals | Signal Transduction - drug effects | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Drug Monitoring | Graft Survival - drug effects | Kidney Transplantation - adverse effects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text The Challenges Associated With a Calcineurin Inhibitor-free Regimen After Heart Transplantation
by Silva, Helio Tedesco
Transplantation, ISSN 0041-1337, 04/2019, Volume 103, Issue 4, pp. 664 - 665
SURGERY | HYPERTROPHY | FREE IMMUNOSUPPRESSION | EVEROLIMUS INITIATION | IMMUNOLOGY | RECIPIENTS | WITHDRAWAL | TRANSPLANTATION
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Randomized trial of everolimus-facilitated calcineurin inhibitor minimization over 24 months in renal transplantation
by Cibrik, Diane and Silva Jr, Helio Tedesco and Vathsala, Anantharaman and Lackova, Eva and Cornu-Artis, Catherine and Walker, Rowan G and Wang, Zailong and Zibari, Gazi B and Shihab, Fuad and Kim, Yu S
Transplantation, ISSN 0041-1337, 04/2013, Volume 95, Issue 7, pp. 933 - 942
Background. Strategies allowing calcineurin inhibitor minimization while maintaining efficacy may improve renal transplant outcomes. Methods. A2309 was a... 
Renal transplantation | Renal function | Cyclosporine | Everolimus | Calcineurin inhibitor toxicity | SURGERY | PREDICTOR | CLASSIFICATION | RISK | IMMUNOLOGY | TRANSPLANTATION | GLOMERULAR-FILTRATION-RATE | REJECTION | DISEASE | GRAFT-SURVIVAL | SIROLIMUS | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Cyclosporine - blood | Calcineurin Inhibitors | Glomerular Filtration Rate - drug effects | Immunosuppressive Agents - blood | Time Factors | Graft Rejection - mortality | Adult | Female | Drug Therapy, Combination | Sirolimus - adverse effects | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Graft Rejection - physiopathology | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Treatment Outcome | Sirolimus - blood | Cyclosporine - therapeutic use | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Cyclosporine - adverse effects | Immunosuppressive Agents - adverse effects | Kidney Transplantation - mortality | Graft Rejection - immunology | Drug Monitoring | Graft Survival - drug effects | Kidney Transplantation - immunology | Kidney Transplantation - adverse effects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text ATHENA: wisdom and warfare in defining the role of de novo mTOR inhibition in kidney transplantation
by Chadban, Steve and Tedesco-Silva, Helio
Kidney International, ISSN 0085-2538, 07/2019, Volume 96, Issue 1, pp. 27 - 30
ATHENA, published in this edition of Kidney International, is the third contemporary, multicenter, randomized, controlled trial to compare de novo use of... 
UROLOGY & NEPHROLOGY | EVEROLIMUS | EFFICACY | RECIPIENTS | SAFETY | CYCLOSPORINE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus
by Ueno, Priscilla and Felipe, Claudia and Ferreira, Alexandra and Cristelli, Marina and Viana, Laila and Mansur, Juliana and Basso, Geovana and Hannun, Pedro and Aguiar, Wilson and Tedesco Silva, Helio and Medina-Pestana, Jose
Transplantation, ISSN 0041-1337, 04/2017, Volume 101, Issue 4, pp. 844 - 850
BACKGROUNDDe novo use of mammalian target of rapamycin inhibitors after kidney transplantation is associated with a concentration-dependent incidence of wound... 
SURGERY | DELAYED GRAFT FUNCTION | DE-NOVO EVEROLIMUS | RISK | IMMUNOLOGY | TRANSPLANTATION | SURGICAL COMPLICATIONS | IMMUNOSUPPRESSION | LYMPHOCELE FORMATION | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | CYCLOSPORINE | Prednisone - adverse effects | Prospective Studies | Recombinant Fusion Proteins - adverse effects | Humans | Middle Aged | Risk Factors | Antibodies, Monoclonal - adverse effects | Male | Treatment Outcome | Tacrolimus - adverse effects | Mycophenolic Acid - adverse effects | Time Factors | Everolimus - adverse effects | Ultrasonography | Brazil | Adult | Female | Immunosuppressive Agents - adverse effects | Drug Therapy, Combination | Wound Healing - drug effects | Antilymphocyte Serum - adverse effects | Kidney Transplantation - adverse effects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation
by Henrique Pinto, Cahue and Tedesco-Silva Jr, Helio and Rosso Felipe, Claudia and Nicolau Ferreira, Alexandra and Cristelli, Marina and Almeida Viana, Laila and Aguiar, Wilson and Medina-Pestana, José
Brazilian Journal of Infectious Diseases, ISSN 1413-8670, 11/2016, Volume 20, Issue 6, pp. 576 - 584
The identification of the best strategy to manage cytomegalovirus infection is hampered by uncertainties regarding the risk/benefit ratios of universal... 
Cytomegalovirus | Kidney | Preemptive therapy | Transplant | SOLID-ORGAN TRANSPLANTATION | DIAGNOSIS | INFECTIOUS DISEASES | MANAGEMENT | PREVENT CYTOMEGALOVIRUS DISEASE | RENAL-TRANSPLANTATION | RECIPIENTS | REAL-TIME PCR | POLYMERASE-CHAIN-REACTION | REJECTION | PREDICTIVE FACTORS | Prospective Studies | Humans | Middle Aged | Risk Factors | Male | Kidney Transplantation - methods | Cytomegalovirus Infections - prevention & control | Female | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Cohort Studies | Kidney Transplantation - adverse effects | Premedication | Tacrolimus - administration & dosage | Infection | Care and treatment | Kidneys | Organ transplant recipients | Cytomegalovirus infections | Transplantation | Health aspects | Infection control
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Influence of ABCC2, CYP2C8, and CYP2J2 Polymorphisms on Tacrolimus and Mycophenolate Sodium–Based Treatment in Brazilian Kidney Transplant Recipients
by Genvigir, Fabiana D. V and Nishikawa, Alvaro M and Felipe, Claudia R and Tedesco‐Silva, Helio and Oliveira, Nagilla and Salazar, Antony B. C and Medina‐Pestana, Jose O and Doi, Sonia Q and Hirata, Mario H and Hirata, Rosario D. C
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, ISSN 0277-0008, 05/2017, Volume 37, Issue 5, pp. 535 - 545
STUDY OBJECTIVE To investigate the influence of single nucleotide polymorphisms (SNPs) in genes encoding metabolizing enzymes (CYP2C8, CYP2J2, and UGT2B7) and... 
UGT | tacrolimus | 2C8 | kidney transplantation | 2B7 | 2J2 | polymorphism | ABCG | CYP | ABCC | mycophenolate sodium | CYP2J2 | CYP2C8 | ABCC2 | UGT2B7 | ABCG2 | SOLID-ORGAN TRANSPLANTATION | CYTOCHROME-P450 2C8 | GENETIC POLYMORPHISMS | HAPLOTYPES | RENAL-TRANSPLANTATION | ADVERSE DRUG-REACTIONS | PHARMACOKINETICS | PHARMACOGENOMICS | PHARMACOLOGY & PHARMACY | EXPOSURE | SIROLIMUS | Prospective Studies | Tacrolimus - blood | Graft Rejection - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Male | Treatment Outcome | Tacrolimus - therapeutic use | Graft Rejection - epidemiology | Immunosuppressive Agents - blood | Mycophenolic Acid - therapeutic use | Cytochrome P-450 Enzyme System - genetics | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | Mycophenolic Acid - blood | Polymorphism, Single Nucleotide | Cytochrome P-450 CYP2C8 - genetics | Graft Rejection - genetics | Brazil - epidemiology | Kidney Transplantation - adverse effects | Medical research | Corticosteroids | Kidneys | Cytochrome P-450 | Organ transplant recipients | Nausea | Transplantation | Tacrolimus | Analysis | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Chromosomes | Immunology | Polymorphism | Kidney transplantation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Reduced Exposure to Calcineurin Inhibitors in Renal Transplantation
by Ekberg, Henrik and Tedesco-Silva, Helio and Demirbas, Alper and Vítko, Štefan and Nashan, Björn and Gürkan, Alp and Margreiter, Raimund and Hugo, Christian and Grinyó, Josep M and Frei, Ulrich and Vanrenterghem, Yves and Daloze, Pierre and Halloran, Philip F and ELITE Symphony Study and ELITE-Symphony Study and Enheten för forskning kring njurfunktion och njursjukdom and Lund University and Renal Research Unit and Lunds universitet
The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 25, pp. 2562 - 2575
This study examines the toxicity of immunosuppressive regimens in renal-transplant recipients. A regimen containing mycophenolate mofetil, daclizumab, low-dose... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Association of clinical events with everolimus exposure in kidney transplant patients receiving reduced cyclosporine
by Shihab, Fuad S and Cibrik, Diane and Chan, Laurence and Kim, Yu Seun and Carmellini, Mario and Walker, Rowan and Zibari, Gazi and Pattison, James and Cornu‐Artis, Catherine and Wang, Zailong and Tedesco‐Silva Jr, Helio
Clinical Transplantation, ISSN 0902-0063, 03/2013, Volume 27, Issue 2, pp. 217 - 226
Background The association between clinical events and everolimus exposure in patients receiving reduced-exposure calcineurin inhibitor therapy is poorly... 
everolimus | exposure | efficacy | therapeutic drug monitoring | kidney transplantation | Therapeutic drug monitoring | Efficacy | Exposure | Everolimus | Kidney transplantation | SURGERY | GLOMERULAR-FILTRATION-RATE | MULTICENTER | SAFETY | RENAL-TRANSPLANTATION | TACROLIMUS | TRANSPLANTATION | Follow-Up Studies | Humans | Immunosuppressive Agents - pharmacokinetics | Immunosuppressive Agents - therapeutic use | Middle Aged | Postoperative Complications - prevention & control | Male | Dose-Response Relationship, Drug | Graft Rejection - epidemiology | Cyclosporine - pharmacokinetics | Adult | Female | Drug Therapy, Combination | Postoperative Complications - chemically induced | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Drug Administration Schedule | Graft Rejection - prevention & control | Graft Survival | Linear Models | Logistic Models | Treatment Outcome | Kidney Transplantation | Postoperative Complications - epidemiology | Sirolimus - pharmacokinetics | Cyclosporine - therapeutic use | Cyclosporine - adverse effects | Cyclosporine - administration & dosage | Survival Analysis | Immunosuppressive Agents - adverse effects | Drug Monitoring
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data
by Knoll, Greg A and Kokolo, Madzouka B and Mallick, Ranjeeta and Beck, Andrew and Buenaventura, Chieny D and Ducharme, Robin and Barsoum, Rashad and Bernasconi, Corrado and Blydt-Hansen, Tom D and Ekberg, Henrik and Felipe, Claudia R and Firth, John and Gallon, Lorenzo and Gelens, Marielle and Glotz, Denis and Gossmann, Jan and Guba, Markus and Morsy, Ahmed Ali and Salgo, Rebekka and Scheuermann, Earnst H and Tedesco-Silva, Helio and Vitko, Stefan and Watson, Christopher and Fergusson, Dean A and Enheten för forskning kring njurfunktion och njursjukdom and Lund University and Renal Research Unit and Lunds universitet
BMJ : British Medical Journal, ISSN 0959-8138, 11/2014, Volume 349, Issue nov24 1, pp. g6679 - g6679
Objective To examine risk of malignancy and death in patients with kidney transplant who receive the immunosuppressive drug sirolimus. Design Systematic review... 
RESEARCH | MAMMALIAN TARGET | MEDICINE, GENERAL & INTERNAL | PHASE-II TRIAL | RENAL-ALLOGRAFT RECIPIENTS | NONMELANOMA SKIN-CANCER | RAPAMYCIN INHIBITORS | COMPARING SIROLIMUS | RANDOMIZED CONTROLLED-TRIAL | CALCINEURIN INHIBITORS | MAINTENANCE IMMUNOSUPPRESSION | MYCOPHENOLATE-MOFETIL | Urologi och njurmedicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Urology and Nephrology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights