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Acta Neuropathologica, ISSN 0001-6322, 4/2012, Volume 123, Issue 4, pp. 539 - 552
Journal Article
Science, ISSN 0036-8075, 12/2017, Volume 358, Issue 6370, pp. 1617 - 1622
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7409, pp. 106 - 110
Medulloblastomas are themost commonmalignant brain tumours in children(1). Identifying and understanding the genetic events that drive these tumours is... 
COMPLEX | STRUCTURAL BASIS | LANDSCAPE | CHILDHOOD | MULTIDISCIPLINARY SCIENCES | GENES | Transcription Factors - chemistry | Humans | Hedgehog Proteins - metabolism | Wnt Proteins - metabolism | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | TCF Transcription Factors - metabolism | Patched Receptors | Cerebellar Neoplasms - classification | DEAD-box RNA Helicases - metabolism | Medulloblastoma - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Child | DEAD-box RNA Helicases - chemistry | DNA Helicases - genetics | Intracellular Signaling Peptides and Proteins - genetics | DNA Helicases - chemistry | Histone-Lysine N-Methyltransferase - genetics | Signal Transduction | Models, Molecular | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nuclear Proteins - chemistry | beta Catenin - metabolism | Genome, Human - genetics | beta Catenin - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Histone Methyltransferases | Histone-Lysine N-Methyltransferase - metabolism | LIM Domain Proteins - genetics | Medulloblastoma - classification | Patched-1 Receptor | Receptors, Cell Surface - genetics | Medulloblastoma | Physiological aspects | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Metastasis | DNA sequencing | Cancer
Journal Article
Neuro-Oncology, ISSN 1522-8517, 2/2011, Volume 13, Issue 2, pp. 165 - 175
Recent studies have established miR-34a as a key effector of the p53 signaling pathway and have implicated its role in multiple cancer types. Here, we... 
Chemosensitivity | MAGE-A | miR-34a | Positive feedback mechanism | Medulloblastoma | p53 | APOPTOSIS | medulloblastoma | MDM2 INTERACTION | CELL-LINES | CLINICAL NEUROLOGY | FEEDBACK LOOP | G2/M ARREST | TUMOR-SUPPRESSIVE MIR-34A | CHEMOTHERAPEUTIC-AGENTS | ONCOLOGY | positive feedback mechanism | PROSTATE-CANCER | GENE-EXPRESSION | CHRONIC LYMPHOCYTIC-LEUKEMIA | chemosensitivity | RNA, Small Interfering - genetics | Luciferases - metabolism | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Humans | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | Neoplasm Proteins - metabolism | Immunoenzyme Techniques | Tumor Suppressor Protein p53 - genetics | Medulloblastoma - pathology | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Antineoplastic Agents - pharmacology | Cerebellar Neoplasms - pathology | Neoplasm Proteins - genetics | Cerebellar Neoplasms - metabolism | Antigens, Neoplasm - genetics | Melanoma-Specific Antigens | Cerebellar Neoplasms - drug therapy | RNA, Messenger - genetics | Tumor Suppressor Protein p53 - metabolism | Medulloblastoma - metabolism | Cisplatin - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mitomycin - pharmacology | Drug Resistance, Neoplasm - genetics | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | MicroRNAs - physiology | Cell Cycle - drug effects | Medulloblastoma - drug therapy | Basic and Translational Investigations
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 8/2004, Volume 166, Issue 3, pp. 407 - 418
We show here that β integrins selectively modulate insulin-like growth factor type I receptor (IGF-IR) signaling in response to IGF stimulation. The β integrin... 
Cell growth | Receptors | Phosphorylation | Epithelial cells | Cell adhesion | Cell lines | CHO cells | Human growth | Integrins | Tumors | Gab1 | PI 3-kinase | Laminin | IRS-1 | Prostate | laminin; prostate; Gab1; IRS-1; PI 3-kinase
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 4/2014, Volume 127, Issue 4, pp. 593 - 603
Journal Article
ACTA NEUROPATHOLOGICA, ISSN 0001-6322, 04/2014, Volume 127, Issue 4, pp. 593 - 603
Neural tumors often express neurotransmitter receptors as markers of their developmental lineage. Although these receptors have been well characterized in... 
STEM-CELLS | GABRA5 | C-MYC | HISTONE H2AX | PROLIFERATION | EXPRESSION PROFILES | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | QHii066 | Medulloblastoma | MYC | POOR-PROGNOSIS | CHILDHOOD MEDULLOBLASTOMA | GABA(A) RECEPTORS | IONIZING-RADIATION | HOXA5 | BRAIN | Allosteric properties
Journal Article
Neuro-Oncology, ISSN 1522-8517, 12/2010, Volume 12, Issue 12, pp. 1244 - 1256
Neuralized (Neurl) is a highly conserved E3 ubiquitin ligase, which in Drosophila acts upon Notch ligands to regulate Notch pathway signaling. Human... 
Deazaneplanocin | Jagged1 | Tumor suppressor | Notch | Neuralized1 | DEVELOPMENTAL REGULATORS | DNA METHYLATION | UBIQUITIN LIGASE | deazaneplanocin | tumor suppressor | PLASMA-MEMBRANE | POLYCOMB | CLINICAL NEUROLOGY | BRAIN-TUMORS | ONCOLOGY | COLORECTAL-CANCER | EMBRYONIC STEM-CELLS | TUMOR-SUPPRESSOR | HISTONE MODIFICATIONS | Transcription Factor HES-1 | Cell Proliferation | Receptors, Notch - metabolism | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | Child, Preschool | Infant | Receptors, Notch - genetics | Ubiquitin-Protein Ligases - physiology | Promoter Regions, Genetic - genetics | Immunoenzyme Techniques | Intercellular Signaling Peptides and Proteins - metabolism | DNA Methylation | Receptors, Notch - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - metabolism | Serrate-Jagged Proteins | Medulloblastoma - pathology | Cell Cycle Proteins - genetics | Adult | Membrane Proteins - metabolism | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Child | Cerebellar Neoplasms - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Drosophila Proteins | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Membrane Proteins - genetics | Cerebellum - metabolism | Down-Regulation | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Medulloblastoma - metabolism | Cerebellar Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Homeodomain Proteins - genetics | Cerebellum - pathology | Phenotype | Adolescent | Cell Line, Tumor | Apoptosis | Calcium-Binding Proteins - genetics | Basic and Translational Investigations
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 04/2014, Volume 127, Issue 4, p. 593
  Neural tumors often express neurotransmitter receptors as markers of their developmental lineage. Although these receptors have been well characterized in... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 08/2004, Volume 166, Issue 3, p. 407
  We show here that beta1 integrins selectively modulate insulin-like growth factor type I receptor (IGF-IR) signaling in response to IGF stimulation. The... 
Enzymes | Glycoproteins | Cell adhesion & migration
Journal Article
The Prostate, ISSN 0270-4137, 06/2005, Volume 64, Issue 1, pp. 83 - 91
BACKGROUND The effect of ionizing radiation on extracellular matrix (ECM)‐mediated cellular functions is an important area of research for translational... 
integrins | prostate cancer | fibronectin | extracellular matrix | Extracellular matrix | Prostate cancer | Fibronectin | Integrins
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2004, Volume 167, Issue 3, pp. 565 - 565
Journal Article