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Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer
Nature reviews. Cancer, ISSN 1474-175X, 2017, Volume 17, Issue 2, pp. 79 - 92
Life Sciences & Biomedicine | Oncology | Science & Technology | Epigenomics | ErbB Receptors - antagonists & inhibitors | Colorectal Neoplasms - genetics | Genomics | Humans | ErbB Receptors - genetics | Transcriptome | Consensus | Colorectal Neoplasms - etiology | Colorectal Neoplasms - immunology | Colorectal Neoplasms - drug therapy | Mutation | Precision Medicine | Care and treatment | Chemotherapy | Usage | Gene mutations | Colorectal cancer | Monoclonal antibodies | Diagnosis | Research | Vascular endothelial growth factor | Cancer | Index Medicus
Journal Article
The lancet oncology, ISSN 1470-2045, 2011, Volume 12, Issue 6, pp. 594 - 603
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | MAP Kinase Kinase 1 - antagonists & inhibitors | PTEN Phosphohydrolase - genetics | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Drug Resistance, Neoplasm | Proto-Oncogene Proteins - genetics | Phosphatidylinositol 3-Kinases - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplasm Metastasis | Class I Phosphatidylinositol 3-Kinases | Proto-Oncogene Proteins B-raf - genetics | Colorectal Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mutation | Colorectal Neoplasms - pathology | Care and treatment | Colorectal cancer | Monoclonal antibodies | Genetic aspects | Metastasis | Health aspects | Cancer | Genes | Index Medicus
Journal Article
Journal of clinical oncology, ISSN 0732-183X, 10/2012, Volume 30, Issue 29, pp. 3570 - 3577
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | Multivariate Analysis | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Follow-Up Studies | Colorectal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Antibodies, Monoclonal - therapeutic use | Male | Young Adult | Antibodies, Monoclonal, Humanized | Likelihood Functions | Neoplasm Metastasis | Neoplasm Invasiveness - pathology | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Cetuximab | Colorectal Neoplasms - mortality | Risk Assessment | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Treatment Outcome | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Aged | Mutation | Colorectal Neoplasms - pathology | Neoplasm Staging | Index Medicus
Journal Article
European journal of cancer (1990), ISSN 0959-8049, 10/2017, Volume 84, pp. 69 - 80
Hindgut | Midgut | Colorectal carcinoma | Predictive | Metastatic | Colon | Prognostic | Life Sciences & Biomedicine | Oncology | Science & Technology | Predictive Value of Tests | Receptor, Epidermal Growth Factor - genetics | Colonic Neoplasms - genetics | Colonic Neoplasms - drug therapy | Colorectal Neoplasms - genetics | Humans | Antineoplastic Agents - therapeutic use | Molecular Diagnostic Techniques | Neoplasm Metastasis | Receptor, Epidermal Growth Factor - metabolism | Rectal Neoplasms - genetics | Colorectal Neoplasms - drug therapy | Biomarkers, Tumor - metabolism | Rectal Neoplasms - pathology | Biomarkers, Tumor - antagonists & inhibitors | Rectal Neoplasms - drug therapy | Precision Medicine | Colorectal Neoplasms - enzymology | Gastrointestinal Microbiome | Treatment Outcome | Rectal Neoplasms - enzymology | Protein Kinase Inhibitors - therapeutic use | Colonic Neoplasms - pathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Biomarkers, Tumor - genetics | Colonic Neoplasms - enzymology | Mutation | Colorectal Neoplasms - pathology | Medical research | Care and treatment | Colorectal cancer | Medicine, Experimental | Drug therapy | Tumors | Cancer | Epidermal growth factor | Metastasis | Spleen | Impact prediction | Microbiomes | Patients | Flexing | Molecular chains | Metastases | Rectum | Index Medicus
Journal Article
Nature reviews. Clinical oncology, ISSN 1759-4774, 09/2009, Volume 6, Issue 9, pp. 519 - 527
Life Sciences & Biomedicine | Oncology | Science & Technology | ras Proteins - genetics | Exons | Colorectal Neoplasms - genetics | Humans | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Patient Selection | Antibodies, Monoclonal, Humanized | Neoplasm Metastasis | Codon | Base Sequence | Colorectal Neoplasms - drug therapy | Cetuximab | Amino Acid Sequence | Signal Transduction - genetics | Antibodies, Monoclonal - genetics | Point Mutation | Drug Resistance, Neoplasm - genetics | Valine - metabolism | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aspartic Acid - metabolism | Biomarkers, Tumor - genetics | ras Proteins - therapeutic use | Colorectal Neoplasms - pathology | Genes, ras | Amino Acid Substitution | Care and treatment | Ras genes | Gene mutations | Patient outcomes | Colorectal cancer | Genetic aspects | Health aspects | Index Medicus
Journal Article
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 10/2013, Volume 70, Issue 20, pp. 3791 - 3811
Life Sciences | Biochemistry, general | Xenopus | Life Sciences, general | Mouse | Transcription | Zic genes | Biomedicine general | Neurological disorders | Cell Biology | Neural development | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Multigene Family | Zinc Fingers | Gastrulation | Xenopus laevis - embryology | Xenopus Proteins - genetics | Homeodomain Proteins - metabolism | Humans | Transcription Factors - genetics | Homeodomain Proteins - genetics | Neural Crest - metabolism | Morphogenesis | Transcription Factors - metabolism | Phenotype | Animals | Gene Expression Regulation, Developmental | Neural Crest - embryology | Xenopus laevis - metabolism | Alleles | Body Patterning | Xenopus Proteins - metabolism | Mice | Xenopus laevis - genetics | Proteins | Genetic disorders | Genes | Genetic research | Development and progression | Genetic transcription | Amphibians | Index Medicus
Journal Article
Journal of clinical oncology, ISSN 0732-183X, 05/2011, Volume 29, Issue 15, pp. 2011 - 2019
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Prognosis | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized | Fluorouracil - therapeutic use | Neoplasm Metastasis | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Leucovorin - therapeutic use | Cetuximab | Camptothecin - analogs & derivatives | Colorectal Neoplasms - mortality | Camptothecin - therapeutic use | Proto-Oncogene Proteins - genetics | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Mutation | Colorectal Neoplasms - pathology | Index Medicus
Journal Article
Journal of clinical oncology, ISSN 0732-183X, 10/2013, Volume 31, Issue 30, pp. 3764 - 3775
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | Colorectal Neoplasms - mortality | Predictive Value of Tests | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras)