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Nature Reviews Clinical Oncology, ISSN 1759-4774, 11/2018, Volume 15, Issue 11, pp. 676 - 693
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 10/2019, Volume 25, Issue 19, pp. 5743 - 5751
Cancer immunotherapies utilizing immune checkpoint inhibitors (ICI) have demonstrated durable efficacy in a proportion of patients with advanced/metastatic... 
BREAST-CANCER | RESPONSES | ACTIVATION | ONCOLOGY | CHEMORADIOTHERAPY | THERAPIES | STAGE-III | CHEMOTHERAPY | IPILIMUMAB | CD8 T-CELLS | ADJUVANT
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 12/2017, Volume 17, Issue 12, pp. 765 - 765
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 10/2018, Volume 96, Issue 9, pp. 883 - 885
Androgen-deprivation therapy is standard-of-care for prostate cancer (PCa). Although nearly all patients respond to treatment, most will eventually progress to... 
DISCOVERY | IMMUNOLOGY | CELL BIOLOGY | Cell proliferation | Signal transduction | Androgens | Chemotherapy | Cell survival | Castration | Tumor cells | Interleukin 23 | Suppressor cells | Prostate cancer | Tumors
Journal Article
OncoImmunology, ISSN 2162-402X, 06/2019, Volume 8, Issue 6, p. e1593809
Tumor metastases are responsible for death in the majority of cancer patients. Here we have explored the role of the ectonucleotidase CD39 in select models of... 
CD39 | lung metastasis | NK | Tumors | TARGET | NATURAL-KILLER-CELLS | CD73 | ADENOSINE | IMMUNOLOGY | CANCER | ONCOLOGY | IMMUNOTHERAPY | GROWTH | REGULATORY T-CELLS | RECEPTORS | EXPRESSION
Journal Article
OncoImmunology, ISSN 2162-402X, 05/2019, Volume 8, Issue 5, p. e1581530
Adjuvant immunotherapies targeting CTLA4 or PD-1 recently demonstrated efficacy in the treatment of earlier stages of human cancer. We previously demonstrated... 
scheduling | metastases | irAEs | Neoadjuvant immunotherapy | surgery | SURVIVAL | STAGE-III MELANOMA | ONCOLOGY | IMMUNOLOGY | NIVOLUMAB | IPILIMUMAB
Journal Article
OncoImmunology, ISSN 2162-4011, 02/2019, Volume 8, Issue 2, p. e1546068
New clinical trials are now evaluating the efficacy of neoadjuvant immunotherapy in the context of primary tumor surgery. Using the orthotopic 4T1.2 mouse... 
mouse models | metastases | + | type I IFN | Batf3 | Neoadjuvant immunotherapy | surgery | DC | RESPONSES | DENDRITIC CELLS | ONCOLOGY | STAGE-III | IMMUNOLOGY | IPILIMUMAB | Batf3(+) DC
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2015, Volume 125, Issue 9, pp. 3338 - 3338
Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although, cancer immunoediting was first... 
Journal Article
The Lancet Oncology, ISSN 1470-2045, 12/2017, Volume 18, Issue 12, pp. e731 - e741
Use of immune checkpoint inhibitors targeting the programmed cell death protein-1/programmed cell death-ligand 1 and cytotoxic T lymphocyte-associated... 
TUMOR-INFILTRATING LYMPHOCYTES | ANTI-PD-1 THERAPY | NEOANTIGEN LANDSCAPE | STAGE-III MELANOMA | ONCOLOGY | PD-1 BLOCKADE | SQUAMOUS-CELL CARCINOMA | METASTATIC UROTHELIAL CARCINOMA | OPEN-LABEL | ANTITUMOR IMMUNITY | MESENCHYMAL TRANSITION | Medicine, Experimental | Medical research | Biological response modifiers | Cell death | Multiprocessing
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2077 - 2089
Multiple myeloma (MM) is an age-dependent hematological malignancy. Evaluation of immune interactions that drive MM relies on in vitro experiments that do not... 
Neoplasm Transplantation | Pore Forming Cytotoxic Proteins - genetics | Neoplasm Proteins - physiology | Neoplasm Proteins - immunology | Antibodies, Monoclonal - therapeutic use | Multiple Myeloma - immunology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Pyrazines - therapeutic use | Genes, myc | Receptors, Virus - genetics | Boronic Acids - therapeutic use | Cyclophosphamide - therapeutic use | Receptors, Virus - physiology | Multiple Myeloma - drug therapy | Receptors, Virus - deficiency | Pore Forming Cytotoxic Proteins - physiology | Antigens, Differentiation, T-Lymphocyte - physiology | Immunotherapy | Killer Cells, Natural - immunology | Interferon-gamma - genetics | Interferon-gamma - deficiency | Neoplasm Proteins - genetics | Genetic Predisposition to Disease | Bortezomib | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Interferon-gamma - physiology | Mice, Transgenic | Pore Forming Cytotoxic Proteins - deficiency | Tumor Burden | Immunologic Surveillance - immunology | Disease Progression | Mice, Knockout | Animals | Tumor Necrosis Factor Receptor Superfamily, Member 9 - antagonists & inhibitors | Antigens, Differentiation, T-Lymphocyte - genetics | Mice | Neoplasm Proteins - deficiency | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Multiple Myeloma - genetics | Crosses, Genetic
Journal Article