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analysis (2) 2
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1. Full Text Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3)
by Poulsen, Anders and William, Anthony and Blanchard, Stéphanie and Lee, Angeline and Nagaraj, Harish and Wang, Haishan and Teo, Eeling and Tan, Evelyn and Goh, Kee Chuan and Dymock, Brian
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 4/2012, Volume 26, Issue 4, pp. 437 - 450
Macrocycles from our Aurora project were screened in a kinase panel and were found to be active on other kinase targets, mainly JAKs, FLT3 and CDKs.... 
Chemistry | Physical Chemistry | FLT3 | Structure-based design | Docking | Inhibitor | JAK2 | Animal Anatomy / Morphology / Histology | Subtype selectivity | Computer Applications in Chemistry | V617F MUTATION | COMPLEX | PROTEIN SECONDARY STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | JAK2/FLT3 | SOLVATION | PREDICTION | MECHANICS | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | THERAPY | BIOPHYSICS | FORCE-FIELD | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Amino Acid Sequence | Heterocyclic Compounds, 4 or More Rings - chemistry | Models, Molecular | Molecular Sequence Data | Pyrimidines - pharmacology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Pyrimidines - chemistry | Sequence Homology, Amino Acid | Protein Kinase Inhibitors - chemistry | Bridged-Ring Compounds - chemistry | Bridged-Ring Compounds - pharmacology | Drug Design | Oxygen - chemistry | Molecular Structure | Protein Kinase Inhibitors - pharmacology | Janus Kinase 2 - antagonists & inhibitors | Tyrosine | Rheumatoid factor | Mutual fund industry | Hydrogen | Rheumatoid arthritis | Oxygen | Inhibitor drugs | Hydrogen bonds | Microstructure | Residues | Panels | Macrocyclic compounds | Inhibitors | Selectivity | Kinases | Ethers
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2. Full Text Structure-based design of Aurora A & B inhibitors
by Poulsen, Anders and William, Anthony and Lee, Angeline and Blanchard, Stéphanie and Teo, Eeling and Deng, Weiping and Tu, Noah and Tan, Evelyn and Sun, Eric and Goh, Kay Lin and Ong, Wai Chung and Ng, Chee Pang and Goh, Kee Chuan and Bonday, Zahid
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 12/2008, Volume 22, Issue 12, pp. 897 - 906
The Aurora family of serine/threonine kinases are mitotic regulators involved in centrosome duplication, formation of the bipolar mitotic spindle and the... 
Chemistry | Bioactive conformation | Physical Chemistry | Structure-based design | Docking | Aurora kinase | Inhibitor | Conformational energy penalty | Animal Anatomy / Morphology / Histology | Subtype selectivity | Computer Applications in Chemistry | HESPERADIN | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLIDE | SOLVATION | MECHANICS | CYTOKINESIS | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | BIOPHYSICS | ACCURATE DOCKING | SCORING FUNCTIONS | REGULATORS | SERINE/THREONINE KINASE | Models, Molecular | Protein Kinase Inhibitors - chemistry | Molecular Structure | Protein Kinase Inhibitors - pharmacology | Aurora Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Proteins | Bipolar disorder | Phosphotransferases | Analysis | Oncology | Pharmacology | Kinases | Cancer
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3. Full Text Effects of individual characteristics on police officers' work-related attitudes
by Lim, Vivien K.G and Teo, Thompson S.H
Journal of Managerial Psychology, ISSN 0268-3946, 08/1998, Volume 13, Issue 5/6, pp. 334 - 342
This study examined the effects of police officers' individual characteristics, namely, ethnicity, gender, locus of control and job tenure on their... 
Control | Job satisfaction | Singapore | Gender | Police | Ethnic groups | Police psychology | Employee motivation | Analysis | Psychological aspects | Studies | Statistical analysis | Employee attitude
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