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by Ghinda, Diana and Chen, Suzan and Bedaiwy, Mahmoud and Jabri, Hussam and Alshardan, Mohammad and Taccone, Michael S and Lai, Carolyn and Rabski, Jessica and Tsai, Eve and Dedek, Annemarie and Xu, Jian and Tsai, Eve and Lombroso, Paul and Hildebrand, Mike and Mothe, Andrea and Tator, Charles H and Siladi, Andrew and Nally, Jaqueline and Stirling, David and Keller, Anastasia and Buckley, Christian and Shum-Siu, Alice and Magnuson, David and Rosenbaum, Benjamin P and Kelly, Michael L and Ahuja, Christopher and Ahuja, Christopher and Nori, Satoshi and Khazaei, Mohamad and Ahlfors, Jan-Eric and Liu, Yang and Wang, Jian and Fuehrmann, Tobias and Pakulska, Malgosia and Hettiaratchi, Marian H and Poon, Peter and Shoichet, Molly S and Fehlings, Michael G and Fehlings, Michael G and Fehlings, Michael G and Hazrati, Lili-Naz and Cherian, Leela and Nilewski, Lizanne and Tour, James M and Kent, Thomas A and Robertson, Claudia S and Wilde, Elisabeth and Newsome, Mary and Scheibel, Randall and Troyanskaya, Maya and Velez, Carmen and Wade, Benjamin and Drennon, Ann Marie and York, Gerald and Bigler, Erin and Abildskov, Tracy and Taylor, Brian and Jaramillo, Carlos and Eapen, Blessen and Belanger, Heather and Morey, Rajendra and Haswell, Courtney and Levin, Harvey and Hinds, Sidney and Walker, William and Walker, William and Kochunov, Peter and Jahanshad, Neda and Thompson, Paul and Tate, David and Statz, Jonathan and Goodrich, Jessica and Goforth, Cdr Carl and Tschiffely, Anna E and Arena, John D and Smith, Douglas H and Wolf, John A and Johnson, Victoria E and Rhodes, James and Friess, Stuart and Lee, Taylor and Lycke, Roy J and Jang, Ikbeom and Vike, Nicole L and Nauman, Eric A and Talavage, Thomas M and Rispoli, Joseph V and Alonso-Escalante, Jose and Fulton, William and Sodhi, Chhinder and Hackam, David J and Nasr, Isam W and Hubbard, W B and Joseph, Binoy and Spry, Malinda L and Vekaria, Hemendra J and Saatman, Kathryn and Sullivan, Patrick G and Sullivan, Patrick G and Vascak, Michal and ...
Journal of Neurotrauma, ISSN 0897-7151, 08/2018, Volume 35, Issue 16, pp. A-1 - A-285
[...]the vast majority of basic science pain research ends at target identification and validation in rodent models of chronic pain without confirmation in... 
Abstracts | Neurosciences | Keywords | Traumatic brain injury | Cytokines | Central nervous system | Inflammation | Gene expression | Trauma | Studies | Brain research | Hospitals | Pain | Rodents | Stem cells | DNA methylation | Biomarkers | Spinal cord injuries | Growth factors | Research centers | Proteins
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 446 - 14
Hepatocellular carcinoma (HCC) cells are metabolically distinct from normal hepatocytes by expressing the high-affinity hexokinase (HK2) and suppressing... 
C-13-METABOLIC FLUX ANALYSIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | GROWTH | PARALLEL LABELING EXPERIMENTS | MASS ISOTOPOMER DISTRIBUTIONS | REDD1 | EXPRESSION | CANCER-THERAPY | MTOR | DELETION | Niacinamide - analogs & derivatives | Metformin - therapeutic use | Humans | Male | Antineoplastic Agents - therapeutic use | Metabolic Flux Analysis | Molecular Targeted Therapy | Carcinogenesis | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - pharmacology | Liver Neoplasms - enzymology | Hypoglycemic Agents - therapeutic use | Hexokinase - antagonists & inhibitors | Metformin - pharmacology | Liver Neoplasms - drug therapy | Oxidative Phosphorylation | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Carcinoma, Hepatocellular - enzymology | Mechanistic Target of Rapamycin Complex 1 - metabolism | Hep G2 Cells | Hypoglycemic Agents - pharmacology | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Sorafenib | Glycolysis | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Hexokinase - metabolism | Phosphorylation | Secretion | Serine | Pyruvic acid | Hepatocellular carcinoma | Fluxes | Glycine | Hexokinase | Liver cancer | Mitochondria | Depletion | Clonal deletion | Oxidative phosphorylation | Hepatocytes | Cell death | Rodents | Glucokinase | Deletion | Tumorigenesis | Lactic acid | Metformin | Inhibition | Apoptosis | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 06/2018, Volume 9, Issue 1, pp. 2539 - 1
In the originally published version of this Article, the colours of the bars in Fig. 4b were inadvertently switched during the production process, such that... 
Glycolysis | Hepatocellular carcinoma | Phosphorylation | Metformin | Oxidative phosphorylation | Hexokinase
Journal Article
by Do, Ron and Stitziel, Nathan O and Won, Hong-Hee and Jørgensen, Anders Berg and Duga, Stefano and Angelica Merlini, Pier and Kiezun, Adam and Farrall, Martin and Goel, Anuj and Zuk, Or and Guella, Illaria and Asselta, Rosanna and Lange, Leslie A and Peloso, Gina M and Auer, Paul L and Girelli, Domenico and Martinelli, Nicola and Farlow, Deborah N and DePristo, Mark A and Roberts, Robert and Stewart, Alexander F. R and Saleheen, Danish and Danesh, John and Epstein, Stephen E and Sivapalaratnam, Suthesh and Hovingh, G. Kees and Kastelein, John J and Samani, Nilesh J and Schunkert, Heribert and Erdmann, Jeanette and Shah, Svati H and Kraus, William E and Davies, Robert and Nikpay, Majid and Johansen, Christopher T and Wang, Jian and Hegele, Robert A and Hechter, Eliana and Marz, Winfried and Kleber, Marcus E and Huang, Jie and Johnson, Anew D and Li, Mingyao and Burke, Greg L and Gross, Myron and Liu, Yongmei and Assimes, Themistocles L and Heiss, Gerardo and Lange, Ethan M and Folsom, Aaron R and Taylor, Herman A and Olivieri, Oliviero and Hamsten, Anders and Clarke, Robert and Reilly, Dermot F and Yin, Wu and Rivas, Manuel A and Donnelly, Peter and Rossouw, Jacques E and Psaty, Bruce M and Herrington, David M and Wilson, James G and Rich, Stephen S and Bamshad, Michael J and Tracy, Russell P and Cupples, L. Aienne and Rader, Daniel J and Reilly, Muredach P and Spertus, John A and Cresci, Sharon and Hartiala, Jaana and Tang, W. H. Wilson and Hazen, Stanley L and Allayee, Hooman and Reiner, Alex P and Carlson, Christopher S and Kooperberg, Charles and Jackson, Rebecca D and Boerwinkle, Eric and Lander, Eric S and Schwartz, Stephen M and Siscovick, David S and McPherson, Ruth and Tybjaerg-Hansen, Anne and Abecasis, Goncalo R and Watkins, Hugh and Nickerson, Deborah A and Ardissino, Diego and Sunyaev, Shamil R and O'Donnell, Christopher J and Altshuler, David and Gabriel, Stacey and Kathiresan, Sekar and Gabriel, Stacey B and Altshuler, David M and Abecasis, Gonçalo R and Daly, Mark J and de Bakker, Paul I. W and Fennell, Tim and Garimella, Kiran and ... and NHLBI Exome Sequencing Project
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7537, pp. 102 - +
Journal Article
by Bhandari, Mohit and Guyatt, Gordon and Tornetta, Paul and Schemitsch, Emil H and Swiontkowski, Marc and Sanders, David and Walter, Stephen D and Gregory Tennent Sanders, David W and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Ford, Michael and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and McKee, Michael D and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, T. Desmond and Pacicca, Donna and Sledge, John B and Foster, Timothy E and Voloshin, Ilva and Bolton, Jill and Carlisle, Hope and Shaughnessy, Lisa and Obremskey, William T and LeCroy, C. Michael and Meinberg, Eric G and Messer, Terry M and Craig, William L and Dirschl, Douglas R and Caudle, Robert and Harris, Tim and Elhert, Kurt and Hage, William and Jones, Robert and Pieahita, Luis and ... and SPRINT Investigators and Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures Investigators
Journal of bone and joint surgery. American volume, ISSN 0021-9355, 2008, Volume 90A, Issue 12, pp. 2567 - 2578
Journal Article
by Schemitsch, Emil H and Bhandari, Mohit and Guyatt, Gordon and Sanders, David W and Swiontkowski, Marc and Tornetta, Paul and Walter, Stephen D and Zdero, Rad and Goslings, J. C and Teague, David and Jeray, Kyle and McKee, Michael D and Sprague, Sheila and Heels-Ansdell, Diane and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and Jones, Alan and O'Brien, Peter and Poolman, Rudolf and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Ford, Michael and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, Desmond and Pacicca, Donna and Sledge, John B and Foster, Timothy E and Voloshin, Ilva and Bolton, Jill and Carlisle, Hope and Shaughnessy, Lisa and Obremskey, William T and LeCroy, C. Michael and Meinberg, Eric G and Messer, Terry M and Craig, William L and ... and Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) Investigators
Journal of bone and joint surgery. American volume, ISSN 0021-9355, 2012, Volume 94A, Issue 19, pp. 1786 - 1793
Journal Article